MA27914A1 - Procede de commande de la structure cristalline du risedronate - Google Patents
Procede de commande de la structure cristalline du risedronateInfo
- Publication number
- MA27914A1 MA27914A1 MA28754A MA28754A MA27914A1 MA 27914 A1 MA27914 A1 MA 27914A1 MA 28754 A MA28754 A MA 28754A MA 28754 A MA28754 A MA 28754A MA 27914 A1 MA27914 A1 MA 27914A1
- Authority
- MA
- Morocco
- Prior art keywords
- risedronate
- controlling
- crystalline structure
- hydrate
- ethylidene
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- IIDJRNMFWXDHID-UHFFFAOYSA-N Risedronic acid Chemical compound OP(=O)(O)C(P(O)(O)=O)(O)CC1=CC=CN=C1 IIDJRNMFWXDHID-UHFFFAOYSA-N 0.000 title abstract 2
- 229940089617 risedronate Drugs 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000013078 crystal Substances 0.000 abstract 1
- 230000006911 nucleation Effects 0.000 abstract 1
- 238000010899 nucleation Methods 0.000 abstract 1
- 238000010979 pH adjustment Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Glass Compositions (AREA)
- Steroid Compounds (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Seasonings (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pyridine Compounds (AREA)
- Yarns And Mechanical Finishing Of Yarns Or Ropes (AREA)
- Pens And Brushes (AREA)
Abstract
Procédé de commande de la structure cristalline du risédronate La présente invention concerne la découverte surprenante selon laquelle la forme hydratée du sel d'acide 3-pyridyl-1-hydroxyéthylidène-1, 1-bisphosphonique (Risédronate) peut être contrôlée de manière sélective dans un procédé qui fait appel à une étape d'ajustement de pH plutôt qu'à une étape de nucléation à base de solvant.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49122203P | 2003-07-30 | 2003-07-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA27914A1 true MA27914A1 (fr) | 2006-05-02 |
Family
ID=34115482
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA28754A MA27914A1 (fr) | 2003-07-30 | 2006-01-26 | Procede de commande de la structure cristalline du risedronate |
Country Status (20)
Country | Link |
---|---|
US (1) | US7002014B2 (fr) |
EP (1) | EP1651656B1 (fr) |
JP (1) | JP4423614B2 (fr) |
KR (1) | KR100786044B1 (fr) |
CN (1) | CN100439377C (fr) |
AT (1) | ATE493423T1 (fr) |
AU (1) | AU2004261561B9 (fr) |
BR (1) | BRPI0413067A (fr) |
CA (1) | CA2529470C (fr) |
CO (1) | CO5660304A2 (fr) |
DE (1) | DE602004030801D1 (fr) |
IL (1) | IL172676A (fr) |
IS (1) | IS2915B (fr) |
MA (1) | MA27914A1 (fr) |
MX (1) | MXPA06001129A (fr) |
NO (1) | NO335393B1 (fr) |
NZ (1) | NZ544030A (fr) |
RU (1) | RU2319706C2 (fr) |
SG (1) | SG144151A1 (fr) |
WO (1) | WO2005012314A1 (fr) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1775302A1 (fr) | 2005-10-11 | 2007-04-18 | Sandoz A/S | Méthode pour la préparation de risedronate de sodium cristallin |
JP5052816B2 (ja) * | 2006-04-26 | 2012-10-17 | 株式会社パーマケム・アジア | 3−ピリジル−1−ヒドロキシエチリデン−1、1−ビスホスホン酸ナトリウム塩2.5水和物a型結晶の製造方法 |
JP5354858B2 (ja) * | 2006-05-09 | 2013-11-27 | 株式会社Adeka | スルホンアミド化合物の金属塩を含有するポリエステル樹脂組成物 |
KR20090005206A (ko) | 2006-05-11 | 2009-01-12 | 인드-스위프트 래버러토리즈 리미티드 | 순수한 리세드론산 또는 염의 제조 방법 |
WO2008044245A2 (fr) * | 2006-10-10 | 2008-04-17 | Matrix Laboratories Ltd | Procédé de préparation de risédronate sodium hemipentahydrate |
KR100828705B1 (ko) * | 2006-12-04 | 2008-05-09 | 씨제이제일제당 (주) | 리세드론산 나트륨 수화물의 제조방법 |
KR100775440B1 (ko) * | 2006-12-20 | 2007-11-12 | 동우신테크 주식회사 | 리세드로네이트 나트륨 헤미펜타히드레이트의 제조방법 |
KR100798855B1 (ko) * | 2007-02-14 | 2008-01-28 | 주식회사 엔지켐 | 리세드론산 나트륨 헤미펜타하이드레이트의 제조방법 |
KR100812528B1 (ko) * | 2007-04-12 | 2008-03-12 | 보령제약 주식회사 | 리세드로네이트 나트륨염의 헤미펜타히드레이트의 선택적결정화방법 |
WO2009050731A2 (fr) * | 2007-06-20 | 2009-04-23 | Alkem Laboratories Ltd | Procédé inédit de préparation de l'acide risédronique |
WO2009034580A1 (fr) * | 2007-09-11 | 2009-03-19 | Fleming Laboratories Limited | Procédé amélioré de préparation de risédronate monosodique hémipentahydraté |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL77243A (en) * | 1984-12-21 | 1996-11-14 | Procter & Gamble | Pharmaceutical compositions containing geminal diphosphonic acid compounds and certain such novel compounds |
KR100274734B1 (ko) * | 1991-11-22 | 2000-12-15 | 제이코버스 코넬리스 레이서 | 리제드로네이트 지연-방출성 조성물 |
US6410520B2 (en) * | 2000-02-01 | 2002-06-25 | The Procter & Gamble Company | Selective crystallization of 3-pyridyl-1-hydroxyethylidene-1, 1-bisphosphonic acid sodium as the hemipentahydrate or monohydrate |
-
2004
- 2004-07-15 BR BRPI0413067-7A patent/BRPI0413067A/pt not_active Application Discontinuation
- 2004-07-15 SG SG200804444-8A patent/SG144151A1/en unknown
- 2004-07-15 CN CNB2004800205190A patent/CN100439377C/zh not_active Expired - Lifetime
- 2004-07-15 JP JP2006521878A patent/JP4423614B2/ja not_active Expired - Lifetime
- 2004-07-15 NZ NZ544030A patent/NZ544030A/en not_active IP Right Cessation
- 2004-07-15 MX MXPA06001129A patent/MXPA06001129A/es active IP Right Grant
- 2004-07-15 WO PCT/US2004/022703 patent/WO2005012314A1/fr active Application Filing
- 2004-07-15 AU AU2004261561A patent/AU2004261561B9/en not_active Expired
- 2004-07-15 DE DE602004030801T patent/DE602004030801D1/de not_active Expired - Lifetime
- 2004-07-15 KR KR1020067000683A patent/KR100786044B1/ko active IP Right Grant
- 2004-07-15 EP EP04778281A patent/EP1651656B1/fr not_active Expired - Lifetime
- 2004-07-15 AT AT04778281T patent/ATE493423T1/de not_active IP Right Cessation
- 2004-07-15 CA CA2529470A patent/CA2529470C/fr not_active Expired - Lifetime
- 2004-07-15 RU RU2006102357/04A patent/RU2319706C2/ru active
- 2004-07-29 US US10/901,692 patent/US7002014B2/en not_active Expired - Lifetime
-
2005
- 2005-12-18 IL IL172676A patent/IL172676A/en active IP Right Grant
-
2006
- 2006-01-25 IS IS8262A patent/IS2915B/is unknown
- 2006-01-26 MA MA28754A patent/MA27914A1/fr unknown
- 2006-02-27 NO NO20060950A patent/NO335393B1/no unknown
- 2006-02-27 CO CO06019211A patent/CO5660304A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN100439377C (zh) | 2008-12-03 |
CO5660304A2 (es) | 2006-07-31 |
KR20060054297A (ko) | 2006-05-22 |
NO20060950L (no) | 2006-02-27 |
IL172676A0 (en) | 2006-04-10 |
SG144151A1 (en) | 2008-07-29 |
DE602004030801D1 (de) | 2011-02-10 |
AU2004261561B2 (en) | 2008-06-26 |
ATE493423T1 (de) | 2011-01-15 |
NZ544030A (en) | 2008-05-30 |
MXPA06001129A (es) | 2006-04-11 |
CA2529470A1 (fr) | 2005-02-10 |
US7002014B2 (en) | 2006-02-21 |
RU2319706C2 (ru) | 2008-03-20 |
AU2004261561A1 (en) | 2005-02-10 |
KR100786044B1 (ko) | 2007-12-17 |
WO2005012314A1 (fr) | 2005-02-10 |
IL172676A (en) | 2010-12-30 |
RU2006102357A (ru) | 2006-07-27 |
JP4423614B2 (ja) | 2010-03-03 |
US20050026869A1 (en) | 2005-02-03 |
BRPI0413067A (pt) | 2006-10-17 |
IS8262A (is) | 2006-01-25 |
EP1651656A1 (fr) | 2006-05-03 |
NO335393B1 (no) | 2014-12-08 |
JP2007500189A (ja) | 2007-01-11 |
IS2915B (is) | 2014-12-15 |
CN1823078A (zh) | 2006-08-23 |
CA2529470C (fr) | 2010-11-23 |
EP1651656B1 (fr) | 2010-12-29 |
AU2004261561B9 (en) | 2008-10-30 |
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