LV11747B - Alpha-1-antichymotrypsin analogues having elastase inhibitory activity - Google Patents
Alpha-1-antichymotrypsin analogues having elastase inhibitory activity Download PDFInfo
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- LV11747B LV11747B LVP-96-386A LV960386A LV11747B LV 11747 B LV11747 B LV 11747B LV 960386 A LV960386 A LV 960386A LV 11747 B LV11747 B LV 11747B
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- analogue
- antihimotrypsin
- human
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- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/221,078 US5674708A (en) | 1989-06-23 | 1994-03-31 | α-1-antichymotrypsin analogues having elastase inhibitory activity |
| PCT/US1994/004735 WO1995027055A1 (en) | 1994-03-31 | 1994-04-29 | α-1-ANTICHYMOTRYPSIN ANALOGUES HAVING ELASTASE INHIBITORY ACTIVITY |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| LV11747A LV11747A (lv) | 1997-04-20 |
| LV11747B true LV11747B (en) | 1997-10-20 |
Family
ID=22826247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LVP-96-386A LV11747B (en) | 1994-03-31 | 1996-10-21 | Alpha-1-antichymotrypsin analogues having elastase inhibitory activity |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5674708A (hu) |
| EP (1) | EP0754228A4 (hu) |
| JP (1) | JPH09512423A (hu) |
| CN (1) | CN1145637A (hu) |
| AU (1) | AU696995B2 (hu) |
| BG (1) | BG100939A (hu) |
| CA (1) | CA2186908A1 (hu) |
| CZ (1) | CZ281796A3 (hu) |
| FI (1) | FI963891A (hu) |
| HU (1) | HUT74901A (hu) |
| LV (1) | LV11747B (hu) |
| NO (1) | NO964022D0 (hu) |
| NZ (1) | NZ269619A (hu) |
| PL (1) | PL316433A1 (hu) |
| SI (1) | SI9420082A (hu) |
| SK (1) | SK138196A3 (hu) |
| WO (1) | WO1995027055A1 (hu) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5723316A (en) * | 1989-06-23 | 1998-03-03 | Trustees Of The University Of Pennsylvania | α-1-antichymotrypsin analogues having chymase inhibiting activity |
| US5827662A (en) * | 1989-06-23 | 1998-10-27 | The Trustees Of The University Of Pennsylvania | Methods for detecting genetic mutations resulting in protease inhibitor insufficiencies |
| US6458777B1 (en) | 1998-03-13 | 2002-10-01 | Mucosal Therapeutics Llc | Methods and compositions for treating and preventing mucositis |
| US6242473B1 (en) * | 1999-01-08 | 2001-06-05 | Maxim Pharmaceuticals, Inc. | Treatment and prevention of reactive oxygen metabolite-mediated cellular damage |
| AU2001292306A1 (en) * | 2000-09-29 | 2002-04-08 | Ono Pharmaceutical Co. Ltd. | Remedies for inflammatory bowel diseases |
| ES2239715T3 (es) * | 2001-04-30 | 2005-10-01 | Switch Biotech Aktiengesellschaft | Utilizacion de la alfa-1 quimotripsina en la preparacion de una composicion para el tratamiento, prevencion o diagnostico de las heridas de dificil cicatrizacion causadas por la diabetes. |
| DE10121255A1 (de) | 2001-04-30 | 2002-11-07 | Switch Biotech Ag | Verwendung von alpha 1-Antichymotrypsin Polypeptiden oder diese kodierende Nukleinsäuren, oder einer ein ACT Polypeptid oder diese kodierende Nukleinsäure exprimierende Zelle, zur Behandlung und/oder Prävention von diabetes-assoziierten und/oder arteriellen schlecht heilenden Wunden und zur Identifizierung von pharmakologisch aktiven Substanzen |
| EP1415664A1 (en) * | 2002-10-30 | 2004-05-06 | Switch Biotech Aktiengesellschaft | Use of alpha 1-antichymotrypsin in combination with alpha-1-antitrypsin for treating/preventing diabetes associated or poorly healing arterial wounds |
| CA2623957A1 (en) * | 2005-09-29 | 2007-04-05 | University Of Alberta | Compositions for and methods of granzyme b inhibition |
| US10531655B2 (en) | 2011-12-02 | 2020-01-14 | The Regents Of The University Of California | Reperfusion protection solution and uses thereof |
| WO2021020509A1 (ja) * | 2019-07-31 | 2021-02-04 | 株式会社ステムリム | 間葉系幹細胞の増殖促進または減少抑制のための組成物 |
| US20210051956A1 (en) * | 2019-08-23 | 2021-02-25 | The Hong Kong University Of Science And Technology | Elasnin, a bacteriostatic agent that has potent antibiofilm activities against both mono- and multi-species biofilm |
| WO2021053058A1 (en) | 2019-09-17 | 2021-03-25 | Mereo Biopharma 4 Limited | Alvelestat for use in the treatment of graft rejection, bronchiolitis obliterans syndrome and graft versus host disease |
| MX2022012942A (es) | 2020-04-16 | 2023-01-11 | Mereo Biopharma 4 Ltd | Metodos que involucran el inhibidor de la elastasa de neutrofilo alvelestat para el tratamiento de enfermedades respiratorias mediadas por deficiencia de alfa-1 antitripsina. |
| AU2022373971A1 (en) | 2021-10-20 | 2024-04-04 | Mereo Biopharma 4 Limited | Neutrophil elastase inhibitors for use in the treatment of fibrosis |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4732973A (en) * | 1984-06-14 | 1988-03-22 | Chiron Corporation | Active site modified protease α-1-antitrypsin inhibitors |
| US4916117A (en) * | 1986-12-24 | 1990-04-10 | John Lezdey | Treatment of inflammation using alpha 1-antichymotrypsin |
| US5008242A (en) * | 1986-12-24 | 1991-04-16 | John Lezdey | Treatment of inflammation using 1-antichymotrypsin |
| US5079336A (en) * | 1989-06-23 | 1992-01-07 | The Trustees Of The University Of Pennsylvania | α-1-antichymotrypsin, analogues and methods of production |
| US5252725A (en) * | 1989-06-23 | 1993-10-12 | The Trustees Of The University Of Pennsylvania | α-1-antichymotrypsin, analogues and methods of production |
| US5723316A (en) * | 1989-06-23 | 1998-03-03 | Trustees Of The University Of Pennsylvania | α-1-antichymotrypsin analogues having chymase inhibiting activity |
| US5266465A (en) * | 1989-06-23 | 1993-11-30 | The Trustees Of The University Of Pennsylvania | α-1-antichymotrypsin, analogues and methods of production |
-
1994
- 1994-03-31 US US08/221,078 patent/US5674708A/en not_active Expired - Fee Related
- 1994-04-29 AU AU73936/94A patent/AU696995B2/en not_active Ceased
- 1994-04-29 EP EP94923869A patent/EP0754228A4/en not_active Ceased
- 1994-04-29 NZ NZ269619A patent/NZ269619A/en unknown
- 1994-04-29 PL PL94316433A patent/PL316433A1/xx unknown
- 1994-04-29 CA CA002186908A patent/CA2186908A1/en not_active Abandoned
- 1994-04-29 SK SK1381-96A patent/SK138196A3/sk unknown
- 1994-04-29 JP JP7525637A patent/JPH09512423A/ja active Pending
- 1994-04-29 WO PCT/US1994/004735 patent/WO1995027055A1/en not_active Application Discontinuation
- 1994-04-29 CZ CZ962817A patent/CZ281796A3/cs unknown
- 1994-04-29 CN CN94195058A patent/CN1145637A/zh active Pending
- 1994-04-29 HU HU9602674A patent/HUT74901A/hu unknown
- 1994-04-29 SI SI9420082A patent/SI9420082A/sl unknown
-
1996
- 1996-09-24 NO NO964022A patent/NO964022D0/no not_active Application Discontinuation
- 1996-09-27 FI FI963891A patent/FI963891A/fi unknown
- 1996-10-21 LV LVP-96-386A patent/LV11747B/en unknown
- 1996-10-28 BG BG100939A patent/BG100939A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU9602674D0 (en) | 1996-11-28 |
| US5674708A (en) | 1997-10-07 |
| NO964022L (no) | 1996-09-24 |
| JPH09512423A (ja) | 1997-12-16 |
| LV11747A (lv) | 1997-04-20 |
| BG100939A (en) | 1997-10-31 |
| FI963891A0 (fi) | 1996-09-27 |
| EP0754228A4 (en) | 1997-12-10 |
| HUT74901A (en) | 1997-02-28 |
| SK138196A3 (en) | 1997-07-09 |
| AU7393694A (en) | 1995-10-23 |
| CN1145637A (zh) | 1997-03-19 |
| NZ269619A (en) | 1998-01-26 |
| AU696995B2 (en) | 1998-09-24 |
| FI963891A (fi) | 1996-09-27 |
| EP0754228A1 (en) | 1997-01-22 |
| NO964022D0 (no) | 1996-09-24 |
| SI9420082A (en) | 1997-06-30 |
| PL316433A1 (en) | 1997-01-06 |
| CA2186908A1 (en) | 1995-10-12 |
| WO1995027055A1 (en) | 1995-10-12 |
| CZ281796A3 (en) | 1997-05-14 |
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