LV10456B - Triazolopyridazine compounds, their production and use - Google Patents
Triazolopyridazine compounds, their production and use Download PDFInfo
- Publication number
- LV10456B LV10456B LVP-93-189A LV930189A LV10456B LV 10456 B LV10456 B LV 10456B LV 930189 A LV930189 A LV 930189A LV 10456 B LV10456 B LV 10456B
- Authority
- LV
- Latvia
- Prior art keywords
- compound
- group
- optionally substituted
- salt
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6178092 | 1992-03-18 | ||
| JP21890492 | 1992-08-18 | ||
| JP1456093 | 1993-02-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| LV10456A LV10456A (lv) | 1995-02-20 |
| LV10456B true LV10456B (en) | 1995-10-20 |
Family
ID=27280691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LVP-93-189A LV10456B (en) | 1992-03-18 | 1993-03-17 | Triazolopyridazine compounds, their production and use |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5389633A (da) |
| EP (1) | EP0562439B1 (da) |
| CN (1) | CN1040874C (da) |
| AT (1) | ATE181075T1 (da) |
| AU (1) | AU654430B2 (da) |
| CA (1) | CA2091874A1 (da) |
| DE (1) | DE69325199T2 (da) |
| DK (1) | DK0562439T3 (da) |
| EE (1) | EE9400357A (da) |
| ES (1) | ES2132147T3 (da) |
| FI (1) | FI104076B1 (da) |
| GR (1) | GR3030817T3 (da) |
| HK (1) | HK1009700A1 (da) |
| HU (2) | HU218791B (da) |
| LT (1) | LT3200B (da) |
| LV (1) | LV10456B (da) |
| MY (1) | MY108967A (da) |
| NO (1) | NO300774B1 (da) |
| NZ (1) | NZ247171A (da) |
| PH (1) | PH29998A (da) |
| RU (1) | RU2130458C1 (da) |
| TW (1) | TW255891B (da) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5571821A (en) * | 1993-05-20 | 1996-11-05 | Texas Biotechnology Corporation | Sulfonamides and derivatives thereof that modulate the activity of endothelin |
| US5464853A (en) * | 1993-05-20 | 1995-11-07 | Immunopharmaceutics, Inc. | N-(5-isoxazolyl)biphenylsulfonamides, N-(3-isoxazolyl)biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin |
| US5591761A (en) * | 1993-05-20 | 1997-01-07 | Texas Biotechnology Corporation | Thiophenyl-, furyl-and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin |
| US5962490A (en) * | 1987-09-25 | 1999-10-05 | Texas Biotechnology Corporation | Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin |
| US5594021A (en) * | 1993-05-20 | 1997-01-14 | Texas Biotechnology Corporation | Thienyl-, furyl- and pyrrolyl sulfonamides and derivatives thereof that modulate the activity of endothelin |
| US5514691A (en) * | 1993-05-20 | 1996-05-07 | Immunopharmaceutics, Inc. | N-(4-halo-isoxazolyl)-sulfonamides and derivatives thereof that modulate the activity of endothelin |
| US5736509A (en) * | 1990-12-14 | 1998-04-07 | Texas Biotechnology Corporation | Cyclic peptide surface feature mimics of endothelin |
| US5482939A (en) * | 1992-03-18 | 1996-01-09 | Takeda Chemical Industries, Ltd. | Triazolopyridazine compounds, their production and use |
| CA2120997A1 (en) * | 1993-04-12 | 1994-10-13 | Akio Miyake | Triazolopyridazine derivatives, their production and use |
| US6613804B2 (en) | 1993-05-20 | 2003-09-02 | Encysive Pharmaceuticals, Inc. | Biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin |
| US6030991A (en) * | 1993-05-20 | 2000-02-29 | Texas Biotechnology Corp. | Benzenesulfonamides and the use thereof to modulate the activity of endothelin |
| US6342610B2 (en) | 1993-05-20 | 2002-01-29 | Texas Biotechnology Corp. | N-aryl thienyl-, furyl-, and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin |
| TW304878B (da) * | 1993-09-21 | 1997-05-11 | Takeda Pharm Industry Co Ltd | |
| CN1046517C (zh) * | 1994-09-16 | 1999-11-17 | 武田药品工业株式会社 | 三唑并哒嗪,其制备和应用 |
| US5977117A (en) * | 1996-01-05 | 1999-11-02 | Texas Biotechnology Corporation | Substituted phenyl compounds and derivatives thereof that modulate the activity of endothelin |
| US5958905A (en) | 1996-03-26 | 1999-09-28 | Texas Biotechnology Corporation | Phosphoramidates, phosphinic amides and related compounds and the use thereof to modulate the activity of endothelin |
| US5804585A (en) * | 1996-04-15 | 1998-09-08 | Texas Biotechnology Corporation | Thieno-pyridine sulfonamides derivatives thereof and related compounds that modulate the activity of endothelin |
| DE69827786T2 (de) * | 1997-04-25 | 2005-11-24 | Takeda Pharmaceutical Co. Ltd. | Condensierte pyridazine derivate,deren herstellung und verwendung |
| CA2281090C (en) | 1997-04-28 | 2005-06-07 | Texas Biotechnology Corporation | Sulfonamide compounds and salts for treatment of endothelin-mediated disorders |
| US5783705A (en) * | 1997-04-28 | 1998-07-21 | Texas Biotechnology Corporation | Process of preparing alkali metal salys of hydrophobic sulfonamides |
| EP1059924A1 (en) * | 1998-03-04 | 2000-12-20 | Takeda Chemical Industries, Ltd. | Triazolo-pyridazine derivatives for the treatment of chronic obstructive pulmonary diseases |
| AU6003099A (en) | 1998-10-06 | 2000-04-26 | Takeda Chemical Industries Ltd. | Fused pyridazine compounds, process for the preparation of the same and uses thereof |
| CA2348022A1 (en) | 1998-10-21 | 2000-04-27 | Takeda Chemical Industries, Ltd. | Condensed pyridazine derivatives, their production and use |
| CN101981035B (zh) * | 2008-02-05 | 2013-08-28 | 赛诺菲-安万特 | 作为par1抑制剂的三唑*盐、其制备及其作为药物的用途 |
| CN102791715B (zh) | 2009-12-31 | 2016-04-27 | 卡洛斯三世国家癌症研究中心基金会 | 用作激酶抑制剂的三环化合物 |
| WO2012098387A1 (en) | 2011-01-18 | 2012-07-26 | Centro Nacional De Investigaciones Oncológicas (Cnio) | 6, 7-ring-fused triazolo [4, 3 - b] pyridazine derivatives as pim inhibitors |
| WO2013005057A1 (en) | 2011-07-07 | 2013-01-10 | Centro Nacional De Investigaciones Oncológicas (Cnio) | New compounds |
| WO2013005041A1 (en) | 2011-07-07 | 2013-01-10 | Centro Nacional De Investigaciones Oncológicas (Cnio) | Tricyclic heterocyclic compounds as kinase inhibitors |
| WO2013004984A1 (en) | 2011-07-07 | 2013-01-10 | Centro Nacional De Investigaciones Oncologicas (Cnio) | Tricyclic compounds for use as kinase inhibitors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3915968A (en) | 1973-09-21 | 1975-10-28 | Lepetit Spa | Triazolopyridazines |
| US4136182A (en) | 1976-05-26 | 1979-01-23 | The Dow Chemical Company | Triazolopyridazines used to alleviate bronchial spasms |
| PH27291A (en) * | 1989-01-31 | 1993-05-04 | Takeda Chemical Industries Ltd | Imidazolpyrimidazines their production and use |
| EP0440119A1 (en) * | 1990-01-31 | 1991-08-07 | Takeda Chemical Industries, Ltd. | Imidazopyridazine compounds, their production and use |
| EP0444549B1 (en) * | 1990-03-01 | 1995-01-25 | Takeda Chemical Industries, Ltd. | Imidazopyridazines their production and use |
-
1993
- 1993-03-05 LT LTIP390A patent/LT3200B/lt not_active IP Right Cessation
- 1993-03-06 TW TW082101665A patent/TW255891B/zh active
- 1993-03-10 MY MYPI93000429A patent/MY108967A/en unknown
- 1993-03-12 RU RU93004584A patent/RU2130458C1/ru active
- 1993-03-16 NZ NZ247171A patent/NZ247171A/en unknown
- 1993-03-16 AU AU35269/93A patent/AU654430B2/en not_active Ceased
- 1993-03-17 EP EP93104367A patent/EP0562439B1/en not_active Expired - Lifetime
- 1993-03-17 LV LVP-93-189A patent/LV10456B/en unknown
- 1993-03-17 ES ES93104367T patent/ES2132147T3/es not_active Expired - Lifetime
- 1993-03-17 US US08/032,296 patent/US5389633A/en not_active Expired - Fee Related
- 1993-03-17 FI FI931190A patent/FI104076B1/fi active
- 1993-03-17 DK DK93104367T patent/DK0562439T3/da active
- 1993-03-17 AT AT93104367T patent/ATE181075T1/de not_active IP Right Cessation
- 1993-03-17 DE DE69325199T patent/DE69325199T2/de not_active Expired - Fee Related
- 1993-03-17 HU HU9300759A patent/HU218791B/hu not_active IP Right Cessation
- 1993-03-17 NO NO930974A patent/NO300774B1/no not_active IP Right Cessation
- 1993-03-17 PH PH45897A patent/PH29998A/en unknown
- 1993-03-17 CA CA002091874A patent/CA2091874A1/en not_active Abandoned
- 1993-03-18 CN CN93103370A patent/CN1040874C/zh not_active Expired - Fee Related
-
1994
- 1994-11-10 EE EE9400357A patent/EE9400357A/xx unknown
-
1995
- 1995-05-31 HU HU95P/P00146P patent/HU211326A9/hu unknown
-
1998
- 1998-09-08 HK HK98110535A patent/HK1009700A1/xx not_active IP Right Cessation
-
1999
- 1999-07-20 GR GR990401905T patent/GR3030817T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69325199T2 (de) | 1999-12-16 |
| DE69325199D1 (de) | 1999-07-15 |
| HU211326A9 (en) | 1995-11-28 |
| MY108967A (en) | 1996-11-30 |
| FI931190A0 (fi) | 1993-03-17 |
| RU2130458C1 (ru) | 1999-05-20 |
| US5389633A (en) | 1995-02-14 |
| HU218791B (hu) | 2000-12-28 |
| PH29998A (en) | 1996-10-29 |
| NZ247171A (en) | 1994-09-27 |
| NO930974D0 (no) | 1993-03-17 |
| FI104076B (fi) | 1999-11-15 |
| EP0562439A1 (en) | 1993-09-29 |
| AU3526993A (en) | 1993-09-23 |
| GR3030817T3 (en) | 1999-11-30 |
| LV10456A (lv) | 1995-02-20 |
| ATE181075T1 (de) | 1999-06-15 |
| AU654430B2 (en) | 1994-11-03 |
| HUT65935A (en) | 1994-08-29 |
| CN1077958A (zh) | 1993-11-03 |
| ES2132147T3 (es) | 1999-08-16 |
| HU9300759D0 (en) | 1993-06-28 |
| EP0562439B1 (en) | 1999-06-09 |
| FI931190A (fi) | 1993-09-19 |
| HK1009700A1 (en) | 1999-06-04 |
| CN1040874C (zh) | 1998-11-25 |
| LT3200B (en) | 1995-03-27 |
| NO930974L (no) | 1993-09-20 |
| FI104076B1 (fi) | 1999-11-15 |
| LTIP390A (lt) | 1994-08-25 |
| NO300774B1 (no) | 1997-07-21 |
| DK0562439T3 (da) | 1999-11-15 |
| TW255891B (da) | 1995-09-01 |
| EE9400357A (et) | 1996-04-15 |
| CA2091874A1 (en) | 1993-09-19 |
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