LU88258I2 - - Google Patents

Info

Publication number
LU88258I2
LU88258I2 LU88258C LU88258C LU88258I2 LU 88258 I2 LU88258 I2 LU 88258I2 LU 88258 C LU88258 C LU 88258C LU 88258 C LU88258 C LU 88258C LU 88258 I2 LU88258 I2 LU 88258I2
Authority
LU
Luxembourg
Prior art keywords
genes
recombinant dna
dna molecules
polypeptides
hosts
Prior art date
Application number
LU88258C
Other languages
English (en)
Inventor
Kenneth Murray
Heinz Ernst Schaller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27260648&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU88258(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of LU88258I2 publication Critical patent/LU88258I2/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5761Hepatitis B
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5761Hepatitis B
    • G01N33/5764Hepatitis B surface antigen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185Escherichia
    • C12R2001/19Escherichia coli
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806Antigenic peptides or proteins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/22Viral peptide or viral protein
    • Y10S930/223Hepatitis related

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Communicable Diseases (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
LU88258C 1978-12-22 1979-12-20 LU88258I2 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB7849907 1978-12-22
GB7850039 1978-12-27
GB7937910 1979-11-01

Publications (1)

Publication Number Publication Date
LU88258I2 true LU88258I2 (es) 1994-02-03

Family

ID=27260648

Family Applications (4)

Application Number Title Priority Date Filing Date
LU88257C LU88257I2 (es) 1978-12-22 1979-12-20
LU88258C LU88258I2 (es) 1978-12-22 1979-12-20
LU88259C LU88259I2 (es) 1978-12-22 1979-12-21
LU88256C LU88256I2 (es) 1978-12-22 1979-12-21

Family Applications Before (1)

Application Number Title Priority Date Filing Date
LU88257C LU88257I2 (es) 1978-12-22 1979-12-20

Family Applications After (2)

Application Number Title Priority Date Filing Date
LU88259C LU88259I2 (es) 1978-12-22 1979-12-21
LU88256C LU88256I2 (es) 1978-12-22 1979-12-21

Country Status (25)

Country Link
US (1) US4710463A (es)
EP (2) EP0374869A1 (es)
JP (5) JP2530801B2 (es)
AT (1) ATE26127T1 (es)
AU (1) AU539535B2 (es)
BR (1) BR7908410A (es)
CY (1) CY1422A (es)
DD (1) DD147855A5 (es)
DE (3) DE182442T1 (es)
DK (2) DK171727B1 (es)
ES (1) ES8105035A1 (es)
FI (1) FI86437C (es)
GR (1) GR73675B (es)
HK (2) HK26688A (es)
IE (1) IE53176B1 (es)
IL (1) IL59007A (es)
IN (1) IN151589B (es)
LU (4) LU88257I2 (es)
MX (1) MX9202875A (es)
NL (2) NL930012I2 (es)
NO (2) NO794196L (es)
NZ (1) NZ192465A (es)
PT (1) PT70626B (es)
SG (1) SG60387G (es)
YU (1) YU44186B (es)

Families Citing this family (156)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2480779B2 (fr) * 1979-08-30 1986-07-18 Anvar Vecteur contenant une sequence nucleotidique de l'antigene de surface du virus de l'hepatite b et procede de fabrication d'une molecule immunogene mettant en oeuvre ce vecteur
US6297355B1 (en) * 1978-12-22 2001-10-02 Biogen, Inc. Polypeptides displaying HBV antigenicity or hbv antigen specificity
IE52036B1 (en) * 1979-05-24 1987-05-27 Univ California Non-passageable viruses
USRE34705E (en) * 1979-08-30 1994-08-23 Institut Pasteur Nucleotidic sequence coding the surface antigen of the hepatitis B virus, vector containing said nucleotidic sequence, process allowing the obtention thereof and antigen obtained thereby
DE3176404D1 (en) * 1980-04-22 1987-10-08 Pasteur Institut Vaccine against viral hepatitis b, method and transformed eucaryotic cells for the preparation of this vaccine
FR2495636B2 (fr) * 1980-12-09 1989-10-06 Pasteur Institut Procede de transformation de cellules, notamment eucaryotes, par un fragment d'adn circulaire du virus de l'hepatite b et preparations contenant les produits d'expression desdits adn
FR2480780B1 (fr) * 1980-04-22 1985-12-06 Pasteur Institut Procede de transformation de cellules, notamment eucaryotes, par un adn circulaire tel que celui du virus de l'hepatite b et preparations contenant les produits d'expression desdits adn
IL63224A (en) * 1980-07-17 1985-05-31 Scripps Clinic Res Synthetic peptide specific antigenic determinant and method of manufacturing antigenic materials therefrom
US5145782A (en) * 1980-12-08 1992-09-08 The Regents Of The University Of California DNA expression vector suitable for direct expression of a foreign gene
NZ199722A (en) 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
EP0062286A1 (en) * 1981-03-31 1982-10-13 Albert Einstein College Of Medicine Of Yeshiva University Diagnostic test for hepatitis B virus
US5332664A (en) * 1981-07-15 1994-07-26 Celltech Limited Human calcitonin precursor polyprotein structural gene
ATE53235T1 (de) * 1981-08-04 1990-06-15 Univ California Synthese von menschlichen viralen antigenen mit hilfe von hefe.
GR76274B (es) * 1981-08-04 1984-08-04 Univ California
US4769238A (en) * 1981-08-04 1988-09-06 The Regents Of The University Of California Synthesis of human virus antigens by yeast
US4803164A (en) * 1981-08-31 1989-02-07 Genentech, Inc. Preparation of hepatitis b surface antigen in yeast
NZ201705A (en) * 1981-08-31 1986-03-14 Genentech Inc Recombinant dna method for production of hepatitis b surface antigen in yeast
ZW18282A1 (en) * 1981-08-31 1983-03-23 Genentech Inc Preparation of polypeptides in vertebrate cell culture
AU8746582A (en) * 1981-09-02 1983-03-10 Biogen N.V. Hepatitis b virus e type antigen
JPS5890517A (ja) * 1981-11-24 1983-05-30 Japan Found Cancer B型肝炎ウイルスの表面抗原を合成する新規な組換え体及びその製法
US4741901A (en) * 1981-12-03 1988-05-03 Genentech, Inc. Preparation of polypeptides in vertebrate cell culture
US7767449B1 (en) * 1981-12-24 2010-08-03 Health Research Incorporated Methods using modified vaccinia virus
US4603112A (en) * 1981-12-24 1986-07-29 Health Research, Incorporated Modified vaccinia virus
US4762708A (en) * 1982-02-18 1988-08-09 University Patents, Inc. Materials and methods for herpes simplex virus vaccination
AU1678783A (en) * 1982-07-20 1984-01-26 Molecular Genetics, Inc. Production of herpes simplex viral proteins
IL69202A (en) * 1982-09-08 1991-08-16 Smith Kline Rit Surface antigen polypeptides of hbv virus produced in yeast and the preparation thereof
US4820642A (en) * 1983-04-04 1989-04-11 The Regents Of The University Of California Amplified expression vector
GB8321789D0 (en) * 1983-08-12 1983-09-14 Biogen Nv Vaccines and compositions against hepatitis
FR2560890B1 (fr) * 1984-03-07 1987-10-16 Grp Genie Genetique Composition utile pour la fabrication de vaccins contenant des particules portant l'antigene de surface du virus de l'hepatite b et le recepteur de l'albumine serique humaine polymerisee, cellules animales capables de produire de telles particules et procede pour leur obtention
WO1985004103A1 (en) * 1984-03-09 1985-09-26 Scripps Clinic And Research Foundation Synthetic hepatitis b virus vaccine including both t cell anc b cell determinants
US5683688A (en) 1984-05-31 1997-11-04 Genentech, Inc. Unglycosylated recombinant human lymphotoxin polypeptides and compositions
IL75318A (en) * 1984-05-31 1994-08-26 Genentech Inc Recombinant human memotoxin and methods for its recombinant production
EP0171908A3 (en) * 1984-07-11 1987-07-15 Takeda Chemical Industries, Ltd. Hepatitis b virus surface antigen and production thereof
US4769239A (en) * 1984-08-21 1988-09-06 Merck & Co., Inc. Vaccine against varicella-zoster virus
US9328391B1 (en) * 1984-08-22 2016-05-03 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Cloning and expression of HIV-1 DNA
US4722840A (en) * 1984-09-12 1988-02-02 Chiron Corporation Hybrid particle immunogens
JPS6170989A (ja) * 1984-09-13 1986-04-11 Takeda Chem Ind Ltd 組み換えdnaおよびその用途
JPS6226300A (ja) * 1984-10-10 1987-02-04 セントコ−・インコ−ポレ−テツド Htlv−3dnaのクロ−ニングおよび発現
GB8431171D0 (en) * 1984-12-11 1985-01-23 Technology Licence Co Ltd Monoclonal antibodies
US6534285B1 (en) 1984-12-24 2003-03-18 Genentech, Inc. Molecularly cloned acquired immunodeficiency syndrome polypeptides and their methods of use
US5853978A (en) * 1985-12-04 1998-12-29 Genentech, Inc. Molecularly cloned acquired immunodeficiency syndrome polypeptides and methods of use
JPS61233700A (ja) * 1984-12-24 1986-10-17 ジエネンテク,インコ−ポレイテツド 分子クロ−ンされたエイズ関連ポリペプチド
FI861417A0 (fi) * 1985-04-15 1986-04-01 Endotronics Inc Hepatitis b ytantigen framstaelld med rekombinant-dna-teknik, vaccin, diagnostiskt medel och cellinjer samt foerfaranden foer framstaellning daerav.
JPH084507B2 (ja) * 1985-10-03 1996-01-24 武田薬品工業株式会社 新規dnaおよびポリペプチド
JPS62236496A (ja) * 1986-04-07 1987-10-16 Green Cross Corp:The HBsAgの製造方法
CA1310602C (en) * 1986-06-03 1992-11-24 Hajime Horii Yeast promoter and process for preparing heterologous protein
ES2061500T5 (es) * 1986-06-17 2003-05-16 Chiron Corp Diagnosis y vacunas de la hepatitis delta, su preparacion y uso.
JPS63214181A (ja) * 1986-07-23 1988-09-06 ベ−リングベルケ、アクチエンゲゼルシャフト ヒト・パピロ−マ・ウイルス18型の発現生成物、これらのタンパク質に特異的な抗体およびこれらの抗体または対応するdnaを含む診断助剤
US4818688A (en) * 1986-11-21 1989-04-04 E. I. Du Pont De Nemours And Company Assays for antibody to hepatitis B core antigen
NZ219515A (en) 1987-02-10 1989-09-27 Wellcome Found Fusion proteins comprising influenza virus ha and a nonnatural antigenic epitope
ATE135403T1 (de) * 1987-03-10 1996-03-15 New England Biolabs Inc Herstellung und reinigung eines proteins, das mit einem bindungsprotein fusioniert ist
WO1988010300A1 (en) * 1987-06-22 1988-12-29 Medico Labs Ag Heterologous viral peptide particle immunogens
US4880750A (en) * 1987-07-09 1989-11-14 Miragen, Inc. Individual-specific antibody identification methods
CA1340876C (en) * 1987-08-10 2000-01-18 Michael Leigh Dyall-Smith The vp7 gene of human rotavirus 4
EP0311228A3 (en) * 1987-10-09 1990-05-02 Repligen Corporation Recombinant polypeptides and their uses, including assay for aids virus
JP2791418B2 (ja) 1987-12-02 1998-08-27 株式会社ミドリ十字 異種蛋白質の製造方法、組換えdna、形質転換体
EP0491077A1 (en) * 1990-12-19 1992-06-24 Medeva Holdings B.V. A composition used as a therapeutic agent against chronic viral hepatic diseases
DE4107612A1 (de) 1991-03-09 1992-09-10 Behringwerke Ag Rekombinante proteine mit der immunreaktivitaet des hepatitis b virus e antigens (hbeag), verfahren zu ihrer herstellung und ihre verwendung in immunoassays und impfstoffen
US5173427A (en) * 1991-08-01 1992-12-22 Becton Dickinson And Company Vectors and hosts with increased expression of HBCAG
US5175272A (en) * 1991-08-01 1992-12-29 Becton Dickinson And Company DNA sequences with increased expression of HBcAg
US5175094A (en) * 1991-08-01 1992-12-29 Becton Dickinson And Company Increased expression of HBcAg
US6607727B1 (en) 1991-08-26 2003-08-19 The Scripps Research Institute Peptides for inducing cytotoxic T lymphocyte responses to hepatitus B virus
US5780036A (en) * 1991-08-26 1998-07-14 The Scripps Research Institute Peptides for inducing cytotoxic T lymphocyte responses to hepattis B virus
US6297048B1 (en) 1992-02-04 2001-10-02 Chiron Corporation Hepatitis therapeutics
US5808032A (en) * 1992-03-30 1998-09-15 Suntory Limited Anti-HBS antibody genes and expression plasmids therefor
US6235288B1 (en) 1992-08-26 2001-05-22 The Scripps Research Institute Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus
FR2711670B1 (fr) * 1993-10-22 1996-01-12 Pasteur Institut Vecteur nucléotidique, composition le contenant et vaccin pour l'immunisation à l'encontre d'une hépatite.
US5726011A (en) * 1994-03-31 1998-03-10 Virginia Commonwealth University Method for diagnosing chronic hepatitis B virus infection
ES2126332T3 (es) * 1994-12-09 1999-03-16 Imp College Innovations Ltd Metodo para la identificacion de genes implicados en la adaptacion de un microorganismo a su entorno.
US5993820A (en) * 1996-11-12 1999-11-30 Michigan State University Chimeric LTB vaccines
US20030100520A1 (en) * 1997-01-21 2003-05-29 Philip Needleman Immunological process and constructs for increasing the hdl cholesterol concentration by dna vaccination
GB9712370D0 (en) 1997-06-14 1997-08-13 Aepact Ltd Therapeutic systems
US6231864B1 (en) 1998-02-12 2001-05-15 Immune Complex Corporation Strategically modified hepatitis B core proteins and their derivatives
JP2002511257A (ja) * 1998-04-14 2002-04-16 カイロン コーポレイション 目的の遺伝子を発現するための非クローニング技術
DE69942925D1 (de) * 1998-09-04 2010-12-16 Emergent Product Dev Uk Ltd Abgeschwächte Salmonella SP12 Mutante als Antigen-Träger.
KR100715954B1 (ko) 1998-12-04 2007-05-09 바이오겐 아이덱 엠에이 인코포레이티드 펩티드 리간드에 의하여 부착된 다중 면역원성 성분을보유한 hbv 코어 항원 입자
EP1230257A4 (en) * 1998-12-23 2003-08-13 Thompson Boyce Plant Res EXPRESSION OF IMMUNOGENOUS HEPATITIS B SURFACE ANTIGEN IN TRANSGENIC PLANTS
GB9910812D0 (en) * 1999-05-10 1999-07-07 Microscience Ltd Vaccine composition
US6268178B1 (en) 1999-05-25 2001-07-31 Phage Biotechnology Corp. Phage-dependent super-production of biologically active protein and peptides
GB0008419D0 (en) * 2000-04-05 2000-05-24 Bioinvent Int Ab A method for invitro molecular evolution of antibody function
GB0008966D0 (en) * 2000-04-13 2000-05-31 Imp College Innovations Ltd Vectors for gene therapy
US7001760B2 (en) * 2000-04-20 2006-02-21 Wang-Schick Ryu Hepatitis B virus vectors for gene therapy
US6583279B1 (en) 2001-01-26 2003-06-24 Becton, Dickinson And Company Sequences and methods for detection of hepatitis B virus
US7202354B2 (en) 2001-03-30 2007-04-10 Abbott Laboratories Hepatitis B virus surface antigen mutant and methods of detection thereof
GB0217033D0 (en) 2002-07-23 2002-08-28 Delta Biotechnology Ltd Gene and polypeptide sequences
US8876532B2 (en) 2002-07-31 2014-11-04 Dentsply International Inc. Bone repair putty
GB0226105D0 (en) * 2002-11-08 2002-12-18 St Georges S Entpr Ltd Pain relief agents
GB0304993D0 (en) * 2003-03-05 2003-04-09 Univ Nottingham Trent Novel screening method
DK1605971T3 (da) * 2003-03-26 2010-08-16 Wyeth Llc Immunogene sammensætninger og fremgangsmåder
WO2005066348A2 (en) * 2004-01-05 2005-07-21 Emd Lexigen Research Center Corp. Interleukin-12 targeted to oncofoetal fibronectin
GB0420091D0 (en) * 2004-09-10 2004-10-13 Univ Nottingham Trent Medical implant materials
US20060193849A1 (en) * 2005-02-25 2006-08-31 Antisoma Plc Biological materials and uses thereof
GB0514661D0 (en) * 2005-07-16 2005-08-24 Medical Res Council Methods
JP4352032B2 (ja) 2005-08-23 2009-10-28 シャープ株式会社 携帯通信機器
DE602005005196T2 (de) 2005-09-05 2008-06-26 Immatics Biotechnologies Gmbh Tumor-assoziierte Peptide, welche an unterschiedliche menschliche Leukozytenantigene der Klasse II binden
ES2330013T3 (es) 2005-09-05 2009-12-03 Immatics Biotechnologies Gmbh Peptidos asociados a tumores unidos a moleculas del antigeno de leucocito humano (hla) de clase i o ii y vacunas contra el cancer relacionadas.
GB0519398D0 (en) * 2005-09-23 2005-11-02 Antisoma Plc Biological materials and uses thereof
GB0607354D0 (en) 2006-04-12 2006-05-24 Bioinvent Int Ab Agent, Composition And Method
GB0607798D0 (en) * 2006-04-20 2006-05-31 Alligator Bioscience Ab Novel polypeptides and use thereof
EP2021791A2 (en) * 2006-05-31 2009-02-11 Unilever N.V. Method of screening for compounds that alter skin and/or hair pigmentation
KR100836745B1 (ko) * 2007-01-31 2008-06-10 (주)두비엘 Hbv 백신 및 그의 제조 방법
NZ592261A (en) 2007-07-27 2012-09-28 Immatics Biotechnologies Gmbh Novel immunotherapy against neuronal and brain tumors
PL2562183T3 (pl) 2007-07-27 2016-03-31 Immatics Biotechnologies Gmbh Nowe epitopy immunogenne do immunoterapii
KR101383476B1 (ko) 2007-11-01 2014-04-11 아스테라스 세이야쿠 가부시키가이샤 면역억제 폴리펩티드 및 핵산
US20100249373A1 (en) * 2007-11-27 2010-09-30 Richard Martin Ogborne Screening methods
CN102851313B (zh) * 2008-01-28 2015-01-28 多贝尔有限公司 一种乙型肝炎疫苗及其制备工艺
DK2105501T3 (da) 2008-03-27 2015-11-23 Immatics Biotechnologies Gmbh Hidtil ukendt immunterapi mod neuronale tumorer og hjernetumorer
HUE024541T2 (hu) 2008-05-14 2016-01-28 Immatics Biotechnologies Gmbh Szurvivinbõl és neurocanból származó új és hatásos II-es osztályú MHC peptidek
EP2326344A4 (en) 2008-06-16 2013-08-07 Prokarium Ltd VACCINES WITH SALMONELLA VECTOR AGAINST CHLAMYDIA AND METHOD OF ADMINISTRATION
EP2172211B1 (en) 2008-10-01 2014-12-03 Immatics Biotechnologies GmbH Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of glioblastoma (GBM) and other cancers
GB0905790D0 (en) 2009-04-03 2009-05-20 Alligator Bioscience Ab Novel polypeptides and use thereof
US9150647B2 (en) 2009-12-18 2015-10-06 Kancera Ab Biological inhibitors of ROR1 capable of inducing cell death
GB201019331D0 (en) 2010-03-19 2010-12-29 Immatics Biotechnologies Gmbh Methods for the diagnosis and treatment of cancer based on AVL9
GB201004551D0 (en) 2010-03-19 2010-05-05 Immatics Biotechnologies Gmbh NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer
GB201020995D0 (en) 2010-12-10 2011-01-26 Bioinvent Int Ab Biological materials and uses thereof
US9452212B2 (en) 2011-04-14 2016-09-27 Dynavax Technologies Corporation Methods and compositions for eliciting an immune response against hepatitis B virus
GB2490655A (en) 2011-04-28 2012-11-14 Univ Aston Modulators of tissue transglutaminase
GB201115280D0 (en) 2011-09-05 2011-10-19 Alligator Bioscience Ab Antibodies, uses and methods
GB201219678D0 (en) 2012-11-01 2012-12-12 Benf Ab Ketone body inhibitors and uses thereof
WO2014134561A2 (en) 2013-03-01 2014-09-04 Boehringer Ingelheim Vetmedica, Inc. Quantification of vaccine compositions
TWI777195B (zh) 2013-08-05 2022-09-11 德商伊瑪提克斯生物科技有限公司 新穎肽類,細胞及其用於治療多種腫瘤的用途,其製造方法及包含其等之醫藥組成物(三)
GB201319446D0 (en) 2013-11-04 2013-12-18 Immatics Biotechnologies Gmbh Personalized immunotherapy against several neuronal and brain tumors
GB201408255D0 (en) 2014-05-09 2014-06-25 Immatics Biotechnologies Gmbh Novel immunotherapy against several tumours of the blood, such as acute myeloid leukemia (AML)
GB201411037D0 (en) 2014-06-20 2014-08-06 Immatics Biotechnologies Gmbh Novel immunotherapy against several tumors of the blood, in particular chronic lymphoid leukemai (CLL)
GB201501017D0 (en) 2014-12-23 2015-03-04 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers
ES2970246T3 (es) 2015-03-27 2024-05-27 Immatics Biotechnologies Gmbh Péptidos novedosos y combinación de péptidos para usarse en inmunoterapia contra diferentes tumores
GB201505585D0 (en) 2015-03-31 2015-05-13 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carinoma (RCC) and other cancers
GB201507030D0 (en) 2015-04-24 2015-06-10 Immatics Biotechnologies Gmbh Immunotherapy against lung cancers, in particular NSCLC
GB201507719D0 (en) 2015-05-06 2015-06-17 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides and scaffolds thereof for use in immunotherapy against colorectal carcinoma (CRC) and other cancers
PE20230321A1 (es) 2015-07-01 2023-02-22 Immatics Biotechnologies Gmbh Nuevos peptidos y nuevas combinaciones de peptidos para el uso en la inmunoterapia contra el cancer de ovario y otros tipos de cancer
GB201511546D0 (en) 2015-07-01 2015-08-12 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
SI3319985T1 (sl) 2015-07-06 2021-01-29 Immatics Biotechnologies Gmbh Novi peptidi in kombinacija peptidov za uporabo v imunoterapiji proti raku prostate in drugim oblikam raka
GB201513921D0 (en) 2015-08-05 2015-09-23 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers
GB201522667D0 (en) 2015-12-22 2016-02-03 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against breast cancer and other cancers
GB201602918D0 (en) 2016-02-19 2016-04-06 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against NHL and other cancers
CN116375797A (zh) 2016-03-01 2023-07-04 伊玛提克斯生物技术有限公司 用于膀胱癌和其他癌症免疫治疗的肽、肽组合物和细胞类药物
CN116731156A (zh) 2016-03-16 2023-09-12 伊玛提克斯生物技术有限公司 用于癌症免疫治疗的转染t细胞和t细胞受体
IL261787B2 (en) 2016-03-16 2023-03-01 Immatics Biotechnologies Gmbh Nucleic acid-treated t-cells and receptor t-cells for use in immunotherapy against types of cancer
CR20180530A (es) 2016-04-06 2019-03-11 Immatics Biotechnologies Gmbh Nuevos peptidos y nuevas combinaciones de peptidos para el uso en la inmunoterapia contra la leucemia mieloide aguda (lma) y otros tipos de cancer
TW202304970A (zh) 2016-08-26 2023-02-01 德商英麥提克生物技術股份有限公司 用於頭頸鱗狀細胞癌和其他癌症免疫治療的新型肽和支架
TWI796314B (zh) 2017-01-27 2023-03-21 德商英麥提克生物技術股份有限公司 用於卵巢癌和其他癌症免疫治療的新型肽和肽組合物
CN111533797A (zh) 2017-04-10 2020-08-14 伊玛提克斯生物技术有限公司 用于癌症免疫治疗的肽及其肽组合物
TW201841934A (zh) 2017-04-10 2018-12-01 德商英麥提克生物技術股份有限公司 用於治療癌症免疫治療的新穎肽及其肽組合物
EA201992416A1 (ru) 2017-04-10 2020-02-25 Имматикс Байотекнолоджиз Гмбх Пептиды и комбинации пептидов для применения в иммунотерапии лейкозов и других видов рака
JP2020530759A (ja) 2017-07-07 2020-10-29 イマティクス バイオテクノロジーズ ゲーエムベーハー Nsclc、sclc、およびその他のがんをはじめとする肺がんに対する免疫療法で使用するための新規ペプチドおよびペプチド併用
WO2019007974A1 (en) 2017-07-07 2019-01-10 Immatics Biotechnologies Gmbh NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY OF LUNG CANCER, INCLUDING NSCLC, CPPC AND OTHER CANCERS
DE102018107224A1 (de) 2018-02-21 2019-08-22 Immatics Biotechnologies Gmbh Peptide und Kombinationen von Peptiden nicht-kanonischen Ursprungs zur Verwendung in der Immuntherapie gegen verschiedene Krebsarten
TW202016131A (zh) 2018-05-16 2020-05-01 德商英麥提克生物技術股份有限公司 用於抗癌免疫治療的肽
US10925947B2 (en) 2018-06-29 2021-02-23 Immatics Biotechnologies Gmbh A*03 restricted peptides for use in immunotherapy against cancers and related methods
TW202019955A (zh) 2018-07-31 2020-06-01 德商英麥提克生物技術股份有限公司 B*07 限制肽和肽組合的抗癌免疫治療和相關方法
US11945850B2 (en) 2018-09-17 2024-04-02 Immatics Biotechnologies Gmbh B*44 restricted peptides for use in immunotherapy against cancers and related methods
TW202024121A (zh) 2018-09-18 2020-07-01 德商英麥提克生物技術股份有限公司 A*01 限制肽和肽組合物在抗癌免疫治療中的用途和相關方法
TW202039535A (zh) 2018-12-18 2020-11-01 德商英麥提克生物技術股份有限公司 B*08限制肽和肽組合物抗癌免疫治療和相關方法
DE102020125457A1 (de) 2020-09-29 2022-03-31 Immatics Biotechnologies Gmbh Amidierte Peptide und ihre deamidierten Gegenstücke, die durch HLA-A*02-Moleküle präsentiert werden, zur Verwendung in der Immuntherapie gegen verschiedene Krebsarten
TW202229312A (zh) 2020-09-29 2022-08-01 德商英麥提克生物技術股份有限公司 由非hla-a*02顯露以用於不同類型癌症之免疫治療的醯胺化肽及其脫醯胺化對應物
TW202241925A (zh) 2021-01-15 2022-11-01 德商英麥提克生物技術股份有限公司 用於不同類型癌症免疫治療的hla展示肽

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4102996A (en) * 1977-04-20 1978-07-25 Merck & Co., Inc. Method of preparing hepatitis B core antigen
FR2444713A1 (fr) * 1978-12-18 1980-07-18 Pasteur Institut Procede de production d'un adn comprenant le genome du virus de l'hepatite b et vecteur le comportant
FR2480779B2 (fr) * 1979-08-30 1986-07-18 Anvar Vecteur contenant une sequence nucleotidique de l'antigene de surface du virus de l'hepatite b et procede de fabrication d'une molecule immunogene mettant en oeuvre ce vecteur
US4241175A (en) * 1978-12-18 1980-12-23 Merck & Co., Inc. Assay for hepatitis B core antibody
IE52036B1 (en) * 1979-05-24 1987-05-27 Univ California Non-passageable viruses
JPH0612193B2 (ja) * 1985-08-23 1994-02-16 日立化成工業株式会社 給 湯 機
DE4326945C2 (de) * 1993-08-11 1996-10-24 Schott Glaswerke Regeleinrichtung für die Gaszufuhr zu einer Gaskocheinrichtung mit unter einer durchgehenden Kochfläche angeordneten Gasstrahlungsbrennern

Also Published As

Publication number Publication date
ES487106A0 (es) 1981-05-16
NZ192465A (en) 1983-09-30
FI86437B (fi) 1992-05-15
DE182442T1 (de) 1988-08-11
HK14991A (en) 1991-03-15
DK84194A (da) 1994-07-12
DE2967697D1 (de) 1990-08-16
DD147855A5 (de) 1981-04-22
SG60387G (en) 1988-09-23
DK171727B1 (da) 1997-04-14
NO794196L (no) 1980-06-24
IE53176B1 (en) 1988-08-17
AU5417079A (en) 1980-06-26
IN151589B (es) 1983-05-28
IE792494L (en) 1980-06-22
YU44186B (en) 1990-04-30
LU88259I2 (es) 1994-02-03
NL930012I2 (nl) 1994-08-16
JP2511962B2 (ja) 1996-07-03
FI794001A (fi) 1980-06-23
NL930012I1 (nl) 1993-05-03
YU312779A (en) 1984-02-29
PT70626A (en) 1980-01-01
JPS63159397A (ja) 1988-07-02
EP0013828B2 (en) 1996-03-20
HK26688A (en) 1988-04-22
JPS6352883A (ja) 1988-03-07
LU88256I2 (es) 1994-02-03
AU539535B2 (en) 1984-10-04
BR7908410A (pt) 1980-09-09
GR73675B (es) 1984-03-29
NL930013I1 (nl) 1993-05-03
ES8105035A1 (es) 1981-05-16
DK548079A (da) 1980-06-23
ATE26127T1 (de) 1987-04-15
FI86437C (fi) 1992-08-25
JPS6366129A (ja) 1988-03-24
JP2512746B2 (ja) 1996-07-03
JPS6356292A (ja) 1988-03-10
IL59007A0 (en) 1980-03-31
JP2527438B2 (ja) 1996-08-21
JP2511961B2 (ja) 1996-07-03
MX9202875A (es) 1992-06-30
CY1422A (en) 1988-09-02
EP0013828B1 (en) 1987-03-25
DE2967652D1 (en) 1987-04-30
JPS55104887A (en) 1980-08-11
US4710463A (en) 1987-12-01
JP2530801B2 (ja) 1996-09-04
IL59007A (en) 1983-11-30
EP0013828A1 (en) 1980-08-06
LU88257I2 (es) 1994-02-03
PT70626B (en) 1983-01-10
NO861548L (no) 1980-06-24
EP0374869A1 (en) 1990-06-27

Similar Documents

Publication Publication Date Title
AU539535B2 (en) Recombinant dna molecules
EP0091527A3 (en) Dna sequences, recombinant dna molecules and processes for producing human serum albumin-like polypeptides
IE811049L (en) Cloned fmdv antigens
KE3747A (en) Recombinant dna,hosts transformed with it and polypeptides produced by the hosts;processes for their preparation;detection processes using the polypeptides;compositions and means containing the polypeptides;dna sequences
DE3853693D1 (de) DNA- und RNA-Moleküle des westlichen Subtyps des FSME-Virus, Polypeptide, die von diesen Molekülen codiert werden, und deren Verwendung.
DK0714441T3 (da) Rekombinante Cladosporium herbarum allergener
MY102686A (en) Recombinant dna molecules and their method of production.
ATA71388A (de) Dna- und rna-moleküle des westlichen subtyps des fsme-virus, polypeptide, die von diesen molekülen codiert werden, und deren verwendung