LU85561A1 - 1,2,4-triazol-3-ones,antidepressives - Google Patents

1,2,4-triazol-3-ones,antidepressives Download PDF

Info

Publication number
LU85561A1
LU85561A1 LU85561A LU85561A LU85561A1 LU 85561 A1 LU85561 A1 LU 85561A1 LU 85561 A LU85561 A LU 85561A LU 85561 A LU85561 A LU 85561A LU 85561 A1 LU85561 A1 LU 85561A1
Authority
LU
Luxembourg
Prior art keywords
compound
formula
radical
hydrogen atom
pharmaceutically acceptable
Prior art date
Application number
LU85561A
Other languages
English (en)
French (fr)
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24145128&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU85561(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of LU85561A1 publication Critical patent/LU85561A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
LU85561A 1983-09-30 1984-09-28 1,2,4-triazol-3-ones,antidepressives LU85561A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/538,027 US4613600A (en) 1983-09-30 1983-09-30 Antidepressant 1,2,4-triazolone compounds
US53802783 1983-09-30

Publications (1)

Publication Number Publication Date
LU85561A1 true LU85561A1 (fr) 1985-06-04

Family

ID=24145128

Family Applications (1)

Application Number Title Priority Date Filing Date
LU85561A LU85561A1 (fr) 1983-09-30 1984-09-28 1,2,4-triazol-3-ones,antidepressives

Country Status (25)

Country Link
US (1) US4613600A (de)
JP (1) JPS60100560A (de)
KR (1) KR880002624B1 (de)
AT (1) AT387963B (de)
AU (1) AU561460B2 (de)
BE (1) BE900714A (de)
CA (1) CA1237723A (de)
CH (1) CH661924A5 (de)
CY (1) CY1541A (de)
DE (1) DE3435745C2 (de)
DK (1) DK169546B1 (de)
ES (1) ES536286A0 (de)
FI (1) FI83310C (de)
FR (1) FR2552759B1 (de)
GB (1) GB2147297B (de)
GR (1) GR80475B (de)
HK (1) HK37391A (de)
IE (1) IE58084B1 (de)
IT (1) IT1178522B (de)
LU (1) LU85561A1 (de)
MY (1) MY102123A (de)
NL (1) NL8402946A (de)
SE (1) SE465928B (de)
YU (1) YU45667B (de)
ZA (1) ZA847589B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4487773A (en) * 1981-03-16 1984-12-11 Mead Johnson & Company 1,2,4-Triazol-3-one antidepressants
YU44721B (en) * 1983-11-30 1990-12-31 Bristol Myers Co Process for obtaining 4-(2-phenoxyethyl)-1,2,4-triazolone
CA1331757C (en) * 1988-02-29 1994-08-30 Janssen Pharmaceutica Naamloze Vennootschap 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols
US5504086A (en) * 1989-10-17 1996-04-02 Ellinwood, Jr.; Everett H. Intraoral dosing method of administering trifluorobenzodiazepines, propoxyphene, and nefazodone
US5256664A (en) * 1992-04-28 1993-10-26 Bristol-Myers Squibb Company Antidepressant 3-halophenylpiperazinylpropyl derivatives of substituted triazolones and triazoldiones
DE4425144A1 (de) * 1994-07-15 1996-01-18 Basf Ag Triazolverbindungen und deren Verwendung
US6403593B1 (en) 1995-07-14 2002-06-11 Abbott Laboratories Triazole compounds and the use thereof
DE19728996A1 (de) 1997-07-07 1999-01-14 Basf Ag Triazolverbindungen und deren Verwendung
US6586437B2 (en) 1999-04-09 2003-07-01 Sepracor Inc. (S)-hydroxynefazodone antipsychotic therapy
AU4215400A (en) 1999-04-09 2000-11-14 Sepracor, Inc. S-hydroxynefazodone
WO2000061128A2 (en) * 1999-04-09 2000-10-19 Sepracor Inc. R-hydroxynefazodone
US6469008B2 (en) 1999-04-09 2002-10-22 Sepracor Inc. (R)-hydroxynefazodone antipsychotic therapy
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
EP1737473A4 (de) * 2004-04-19 2009-08-26 Noven Therapeutics Llc Lithium-kombinationen und relevante verwendungen
CN103259027A (zh) 2005-04-28 2013-08-21 普罗透斯数字保健公司 药物信息系统
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(rap)-접합체 투여에 의한 간 질환의 치료
US9339500B2 (en) * 2008-03-04 2016-05-17 Intra-Cellular Therapies, Inc. Methods of treating vasomotor symptoms
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
TWI556839B (zh) 2009-05-06 2016-11-11 研究室護膚股份有限公司 包含活性劑-磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
WO2012072665A1 (en) 2010-11-30 2012-06-07 Pharmaneuroboost N.V. Compositions comprising pipamperone and serotonin antagonist reuptake inhibitors
US9072660B2 (en) 2011-09-09 2015-07-07 The Board Of Trustees Of The Leland Stanford Junior University Topical itraconazole formulations and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1066857B (it) * 1965-12-15 1985-03-12 Acraf Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione
IT1052119B (it) * 1972-10-16 1981-06-20 Sigma Tau Ind Farmaceuti Derivati del triazolinone e procedimento per la loro preparazione
US4338317A (en) * 1981-03-16 1982-07-06 Mead Johnson & Company Phenoxyethyl-1,2,4,-triazol-3-one antidepressants

Also Published As

Publication number Publication date
CH661924A5 (de) 1987-08-31
AT387963B (de) 1989-04-10
DE3435745A1 (de) 1985-04-11
CA1237723A (en) 1988-06-07
DK468284D0 (da) 1984-09-28
BE900714A (fr) 1985-03-28
DK169546B1 (da) 1994-11-28
YU45667B (sh) 1992-07-20
IT8422922A0 (it) 1984-09-28
ES8601966A1 (es) 1985-11-16
IE58084B1 (en) 1993-06-30
HK37391A (en) 1991-05-24
DK468284A (da) 1985-03-31
ATA310884A (de) 1988-09-15
YU172184A (en) 1986-10-31
US4613600A (en) 1986-09-23
ZA847589B (en) 1985-05-29
AU561460B2 (en) 1987-05-07
GR80475B (en) 1985-01-31
DE3435745C2 (de) 1994-11-03
ES536286A0 (es) 1985-11-16
JPH0542435B2 (de) 1993-06-28
IT1178522B (it) 1987-09-09
CY1541A (en) 1991-03-22
SE465928B (sv) 1991-11-18
GB2147297B (en) 1987-04-15
NL8402946A (nl) 1985-04-16
SE8404869L (sv) 1985-03-31
MY102123A (en) 1992-03-31
FI843779L (fi) 1985-03-31
GB8424535D0 (en) 1984-11-07
KR850002270A (ko) 1985-05-10
FI843779A0 (fi) 1984-09-26
IE842476L (en) 1985-03-30
FR2552759B1 (fr) 1988-10-07
FI83310B (fi) 1991-03-15
FI83310C (fi) 1991-06-25
JPS60100560A (ja) 1985-06-04
AU3364884A (en) 1985-04-04
SE8404869D0 (sv) 1984-09-28
FR2552759A1 (fr) 1985-04-05
GB2147297A (en) 1985-05-09
KR880002624B1 (ko) 1988-12-07

Similar Documents

Publication Publication Date Title
LU85561A1 (fr) 1,2,4-triazol-3-ones,antidepressives
LU84011A1 (fr) 2-phenoxyalkyl-1,2,4-triazol-3-ones antidepressives
EP0202164B1 (de) (Benzoyl-4-piperidino)-2-phenyl-1-alkanolderivate, ihre Herstellung und ihre Verwendung als Heilmittel
BE851310A (fr) Nouveaux derives de la tetrahydro-equinocandine b
LU79761A1 (fr) Procede de preparation de nouveaux composes de phtalazine et de composition pharmaceutique les contenant
CH642618A5 (fr) Phenethanolamines et compositions pharmaceutiques en contenant.
EP1315709A1 (de) Aminoalkykbenzoyl-benzofurane oder benzothiophene, verfahren zu ihrer herstellung und die enthaltende zusammensetzungen
EP0341231B1 (de) Substituierte 1-(1H-Imidazol-4-yl)alkyl-Benzamide
EP0004494B1 (de) 1,3-Dihydro-3-(1-(2-(2,3-dihydro-1,4-benzodioxin-2-yl)2-hydroxy-äthyl)piperidin-4-yl)2H-indol-2-on Derivate, Verfahren zu ihrer Herstellung, ihre Verwendung als Arzneimittel und diese enthaltende pharmazeutische Zubereitungen
EP0269599B1 (de) Substituierte 1H-Imidazole
FR2522658A1 (fr) Application a titre de medicaments de derives du trans 4-amino benz (c,d) indol-5-ol ainsi que de leurs sels, compositions les renfermant, nouveaux derives et leur procede de preparation
FR2558158A1 (fr) Derives de l'indole ethenyl phenol, leurs sels, procede de preparation, application a titre de medicaments, compositions les renfermant et intermediaires
EP0275742B1 (de) 5-Hydroxymethyl-Derivate des 2-Oxazolidinons, deren Herstellung und deren Anwendung in der Therapie
LU86405A1 (fr) Derive antipsychotique du benzisothiazole s-oxyde
EP0008259A1 (de) Piperidylbenzimidazolinon-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
CA1100968A (fr) Procedes de preparation de nouvelles piperazines disubstituees
EP0433167B1 (de) Piperidinderivate, Verfahren zur Herstellung sowie diese enthaltende pharmazeutische Präparate
EP0275762B1 (de) Indol-Carboxamid-Derivate und ihre Salze, Verfahren und Zwischenprodukte zur Herstellung, Anwendung als Heilmittel und Zusammenstellungen, die sie enthalten
EP0259228B1 (de) 5-Aminomethyl-2-oxazolidinon-Derivate, ihre Herstellung und ihre Anwendung in der Heilkunde
FR2647451A1 (fr) Derives d'imidazo(1,2-a)pyridine, procede de preparation, compositions pharmaceutiques les contenant
FR2677355A1 (fr) Nouveaux derives de l'oxazole, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2677477A1 (fr) Nouveaux derives de l'oxazole leur preparation, leur utilisation et les compositions pharmaceutiques qui les contiennent.
FR2549054A1 (fr) 1-phenoxy-3-hydroxyindolylalkylamino-2-propanols, leur preparation et leur application pharmacologique
EP0662081B1 (de) Ureidoacetamid-derivate,irhe herstellung und sie enthaltende medikamente
EP0157762B1 (de) Substituierte, piperidinoguanidine, verfahren zu ihrer herstellung, und diese enthaltende pharmazeutische zusammensetzungen