IT1178522B - Composti di 1,2,4-triazolone ad attivita' antidepressiva - Google Patents

Composti di 1,2,4-triazolone ad attivita' antidepressiva

Info

Publication number
IT1178522B
IT1178522B IT22922/84A IT2292284A IT1178522B IT 1178522 B IT1178522 B IT 1178522B IT 22922/84 A IT22922/84 A IT 22922/84A IT 2292284 A IT2292284 A IT 2292284A IT 1178522 B IT1178522 B IT 1178522B
Authority
IT
Italy
Prior art keywords
triazolone compounds
depressive activity
depressive
activity
triazolone
Prior art date
Application number
IT22922/84A
Other languages
English (en)
Other versions
IT8422922A0 (it
Inventor
Richard E Gammans
David W Smith
Joseph P Yevich
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24145128&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1178522(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IT8422922A0 publication Critical patent/IT8422922A0/it
Application granted granted Critical
Publication of IT1178522B publication Critical patent/IT1178522B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IT22922/84A 1983-09-30 1984-09-28 Composti di 1,2,4-triazolone ad attivita' antidepressiva IT1178522B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/538,027 US4613600A (en) 1983-09-30 1983-09-30 Antidepressant 1,2,4-triazolone compounds

Publications (2)

Publication Number Publication Date
IT8422922A0 IT8422922A0 (it) 1984-09-28
IT1178522B true IT1178522B (it) 1987-09-09

Family

ID=24145128

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22922/84A IT1178522B (it) 1983-09-30 1984-09-28 Composti di 1,2,4-triazolone ad attivita' antidepressiva

Country Status (25)

Country Link
US (1) US4613600A (it)
JP (1) JPS60100560A (it)
KR (1) KR880002624B1 (it)
AT (1) AT387963B (it)
AU (1) AU561460B2 (it)
BE (1) BE900714A (it)
CA (1) CA1237723A (it)
CH (1) CH661924A5 (it)
CY (1) CY1541A (it)
DE (1) DE3435745C2 (it)
DK (1) DK169546B1 (it)
ES (1) ES536286A0 (it)
FI (1) FI83310C (it)
FR (1) FR2552759B1 (it)
GB (1) GB2147297B (it)
GR (1) GR80475B (it)
HK (1) HK37391A (it)
IE (1) IE58084B1 (it)
IT (1) IT1178522B (it)
LU (1) LU85561A1 (it)
MY (1) MY102123A (it)
NL (1) NL8402946A (it)
SE (1) SE465928B (it)
YU (1) YU45667B (it)
ZA (1) ZA847589B (it)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4487773A (en) * 1981-03-16 1984-12-11 Mead Johnson & Company 1,2,4-Triazol-3-one antidepressants
YU44721B (en) * 1983-11-30 1990-12-31 Bristol Myers Co Process for obtaining 4-(2-phenoxyethyl)-1,2,4-triazolone
CA1331757C (en) * 1988-02-29 1994-08-30 Janssen Pharmaceutica Naamloze Vennootschap 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols
US5504086A (en) * 1989-10-17 1996-04-02 Ellinwood, Jr.; Everett H. Intraoral dosing method of administering trifluorobenzodiazepines, propoxyphene, and nefazodone
US5256664A (en) * 1992-04-28 1993-10-26 Bristol-Myers Squibb Company Antidepressant 3-halophenylpiperazinylpropyl derivatives of substituted triazolones and triazoldiones
DE4425144A1 (de) * 1994-07-15 1996-01-18 Basf Ag Triazolverbindungen und deren Verwendung
US6403593B1 (en) 1995-07-14 2002-06-11 Abbott Laboratories Triazole compounds and the use thereof
DE19728996A1 (de) 1997-07-07 1999-01-14 Basf Ag Triazolverbindungen und deren Verwendung
JP2002541192A (ja) 1999-04-09 2002-12-03 セプラコール， インク． Ｓ−ヒドロキシネファゾドン
AU4215300A (en) 1999-04-09 2000-11-14 Sepracor, Inc. R-hydroxynefazodone
US6586437B2 (en) 1999-04-09 2003-07-01 Sepracor Inc. (S)-hydroxynefazodone antipsychotic therapy
US6469008B2 (en) 1999-04-09 2002-10-22 Sepracor Inc. (R)-hydroxynefazodone antipsychotic therapy
US20030129186A1 (en) 2001-07-25 2003-07-10 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
EP1737473A4 (en) * 2004-04-19 2009-08-26 Noven Therapeutics Llc COMBINATIONS OF LITHIUM AND USES THEREOF
PT1889198E (pt) 2005-04-28 2015-03-06 Proteus Digital Health Inc Sistema fármaco-informático
WO2008036682A2 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
US9339500B2 (en) * 2008-03-04 2016-05-17 Intra-Cellular Therapies, Inc. Methods of treating vasomotor symptoms
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
WO2012072665A1 (en) 2010-11-30 2012-06-07 Pharmaneuroboost N.V. Compositions comprising pipamperone and serotonin antagonist reuptake inhibitors
US9072660B2 (en) 2011-09-09 2015-07-07 The Board Of Trustees Of The Leland Stanford Junior University Topical itraconazole formulations and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1066857B (it) * 1965-12-15 1985-03-12 Acraf Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione
IT1052119B (it) * 1972-10-16 1981-06-20 Sigma Tau Ind Farmaceuti Derivati del triazolinone e procedimento per la loro preparazione
US4338317A (en) * 1981-03-16 1982-07-06 Mead Johnson & Company Phenoxyethyl-1,2,4,-triazol-3-one antidepressants

Also Published As

Publication number Publication date
AT387963B (de) 1989-04-10
IE58084B1 (en) 1993-06-30
FR2552759A1 (fr) 1985-04-05
GB2147297B (en) 1987-04-15
FI843779L (fi) 1985-03-31
MY102123A (en) 1992-03-31
JPS60100560A (ja) 1985-06-04
SE8404869D0 (sv) 1984-09-28
FI83310B (fi) 1991-03-15
CY1541A (en) 1991-03-22
YU172184A (en) 1986-10-31
DE3435745C2 (de) 1994-11-03
ES8601966A1 (es) 1985-11-16
AU561460B2 (en) 1987-05-07
JPH0542435B2 (it) 1993-06-28
GB2147297A (en) 1985-05-09
KR850002270A (ko) 1985-05-10
GB8424535D0 (en) 1984-11-07
FI843779A0 (fi) 1984-09-26
NL8402946A (nl) 1985-04-16
US4613600A (en) 1986-09-23
HK37391A (en) 1991-05-24
GR80475B (en) 1985-01-31
ES536286A0 (es) 1985-11-16
IE842476L (en) 1985-03-30
CA1237723A (en) 1988-06-07
KR880002624B1 (ko) 1988-12-07
DE3435745A1 (de) 1985-04-11
LU85561A1 (fr) 1985-06-04
BE900714A (fr) 1985-03-28
ATA310884A (de) 1988-09-15
ZA847589B (en) 1985-05-29
DK468284A (da) 1985-03-31
FR2552759B1 (fr) 1988-10-07
CH661924A5 (de) 1987-08-31
FI83310C (fi) 1991-06-25
AU3364884A (en) 1985-04-04
SE465928B (sv) 1991-11-18
IT8422922A0 (it) 1984-09-28
DK169546B1 (da) 1994-11-28
YU45667B (sh) 1992-07-20
DK468284D0 (da) 1984-09-28
SE8404869L (sv) 1985-03-31

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970929