FR2552759B1 - Composes de la 1,2,4-triazolone et leur application pharmacologique - Google Patents

Composes de la 1,2,4-triazolone et leur application pharmacologique

Info

Publication number
FR2552759B1
FR2552759B1 FR8414932A FR8414932A FR2552759B1 FR 2552759 B1 FR2552759 B1 FR 2552759B1 FR 8414932 A FR8414932 A FR 8414932A FR 8414932 A FR8414932 A FR 8414932A FR 2552759 B1 FR2552759 B1 FR 2552759B1
Authority
FR
France
Prior art keywords
triazolone compounds
pharmacological application
pharmacological
triazolone
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8414932A
Other languages
English (en)
Other versions
FR2552759A1 (fr
Inventor
Richard E Gammans
David W Smith
Joseph P Yevich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24145128&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2552759(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FR2552759A1 publication Critical patent/FR2552759A1/fr
Application granted granted Critical
Publication of FR2552759B1 publication Critical patent/FR2552759B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms
FR8414932A 1983-09-30 1984-09-28 Composes de la 1,2,4-triazolone et leur application pharmacologique Expired FR2552759B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/538,027 US4613600A (en) 1983-09-30 1983-09-30 Antidepressant 1,2,4-triazolone compounds

Publications (2)

Publication Number Publication Date
FR2552759A1 FR2552759A1 (fr) 1985-04-05
FR2552759B1 true FR2552759B1 (fr) 1988-10-07

Family

ID=24145128

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8414932A Expired FR2552759B1 (fr) 1983-09-30 1984-09-28 Composes de la 1,2,4-triazolone et leur application pharmacologique

Country Status (25)

Country Link
US (1) US4613600A (fr)
JP (1) JPS60100560A (fr)
KR (1) KR880002624B1 (fr)
AT (1) AT387963B (fr)
AU (1) AU561460B2 (fr)
BE (1) BE900714A (fr)
CA (1) CA1237723A (fr)
CH (1) CH661924A5 (fr)
CY (1) CY1541A (fr)
DE (1) DE3435745C2 (fr)
DK (1) DK169546B1 (fr)
ES (1) ES536286A0 (fr)
FI (1) FI83310C (fr)
FR (1) FR2552759B1 (fr)
GB (1) GB2147297B (fr)
GR (1) GR80475B (fr)
HK (1) HK37391A (fr)
IE (1) IE58084B1 (fr)
IT (1) IT1178522B (fr)
LU (1) LU85561A1 (fr)
MY (1) MY102123A (fr)
NL (1) NL8402946A (fr)
SE (1) SE465928B (fr)
YU (1) YU45667B (fr)
ZA (1) ZA847589B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4487773A (en) * 1981-03-16 1984-12-11 Mead Johnson & Company 1,2,4-Triazol-3-one antidepressants
YU44721B (en) * 1983-11-30 1990-12-31 Bristol Myers Co Process for obtaining 4-(2-phenoxyethyl)-1,2,4-triazolone
CA1331757C (fr) * 1988-02-29 1994-08-30 Janssen Pharmaceutica Naamloze Vennootschap 5-lipoxygenase inhibant les 4-(4-phenyl-1-piperazinyl)phenols
US5504086A (en) * 1989-10-17 1996-04-02 Ellinwood, Jr.; Everett H. Intraoral dosing method of administering trifluorobenzodiazepines, propoxyphene, and nefazodone
US5256664A (en) * 1992-04-28 1993-10-26 Bristol-Myers Squibb Company Antidepressant 3-halophenylpiperazinylpropyl derivatives of substituted triazolones and triazoldiones
DE4425144A1 (de) * 1994-07-15 1996-01-18 Basf Ag Triazolverbindungen und deren Verwendung
US6403593B1 (en) 1995-07-14 2002-06-11 Abbott Laboratories Triazole compounds and the use thereof
DE19728996A1 (de) 1997-07-07 1999-01-14 Basf Ag Triazolverbindungen und deren Verwendung
US6586437B2 (en) 1999-04-09 2003-07-01 Sepracor Inc. (S)-hydroxynefazodone antipsychotic therapy
US6469008B2 (en) 1999-04-09 2002-10-22 Sepracor Inc. (R)-hydroxynefazodone antipsychotic therapy
DE60028955T2 (de) * 1999-04-09 2007-07-05 Sepracor Inc., Marlborough R-hydroxynefazodon
US6465469B1 (en) 1999-04-09 2002-10-15 Sepracor Inc. S-hydroxynefazodone
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
US20050233010A1 (en) * 2004-04-19 2005-10-20 Satow Philip M Lithium combinations, and uses related thereto
SI1889198T1 (sl) 2005-04-28 2015-02-27 Proteus Digital Health, Inc. Farma-informacijski sistem
MX2009002893A (es) 2006-09-18 2009-07-10 Raptor Pharmaceutical Inc Tratamiento de trastornos hepaticos mediante la administracion de conjugados de la proteina asociada al receptor (rap).
US9339500B2 (en) * 2008-03-04 2016-05-17 Intra-Cellular Therapies, Inc. Methods of treating vasomotor symptoms
WO2010095940A2 (fr) 2009-02-20 2010-08-26 To-Bbb Holding B.V. Sustème d'administration de médicament à base de glutathionne
NZ596876A (en) 2009-05-06 2014-01-31 Lab Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
WO2012072665A1 (fr) 2010-11-30 2012-06-07 Pharmaneuroboost N.V. Compositions comprenant de la pipampérone et des antagonistes/inhibiteurs de la recapture de la sérotonine
US9072660B2 (en) 2011-09-09 2015-07-07 The Board Of Trustees Of The Leland Stanford Junior University Topical itraconazole formulations and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1066857B (it) * 1965-12-15 1985-03-12 Acraf Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione
IT1052119B (it) * 1972-10-16 1981-06-20 Sigma Tau Ind Farmaceuti Derivati del triazolinone e procedimento per la loro preparazione
US4338317A (en) * 1981-03-16 1982-07-06 Mead Johnson & Company Phenoxyethyl-1,2,4,-triazol-3-one antidepressants

Also Published As

Publication number Publication date
YU45667B (sh) 1992-07-20
ES8601966A1 (es) 1985-11-16
GB2147297B (en) 1987-04-15
KR880002624B1 (ko) 1988-12-07
DK468284D0 (da) 1984-09-28
FR2552759A1 (fr) 1985-04-05
AU3364884A (en) 1985-04-04
ES536286A0 (es) 1985-11-16
FI83310B (fi) 1991-03-15
CA1237723A (fr) 1988-06-07
HK37391A (en) 1991-05-24
YU172184A (en) 1986-10-31
IE842476L (en) 1985-03-30
AU561460B2 (en) 1987-05-07
CY1541A (en) 1991-03-22
BE900714A (fr) 1985-03-28
AT387963B (de) 1989-04-10
FI83310C (fi) 1991-06-25
SE8404869L (sv) 1985-03-31
DE3435745C2 (de) 1994-11-03
IT8422922A0 (it) 1984-09-28
ZA847589B (en) 1985-05-29
DE3435745A1 (de) 1985-04-11
SE8404869D0 (sv) 1984-09-28
ATA310884A (de) 1988-09-15
IE58084B1 (en) 1993-06-30
NL8402946A (nl) 1985-04-16
SE465928B (sv) 1991-11-18
IT1178522B (it) 1987-09-09
CH661924A5 (de) 1987-08-31
GB8424535D0 (en) 1984-11-07
FI843779A0 (fi) 1984-09-26
JPS60100560A (ja) 1985-06-04
DK468284A (da) 1985-03-31
MY102123A (en) 1992-03-31
JPH0542435B2 (fr) 1993-06-28
DK169546B1 (da) 1994-11-28
FI843779L (fi) 1985-03-31
LU85561A1 (fr) 1985-06-04
GR80475B (en) 1985-01-31
GB2147297A (en) 1985-05-09
US4613600A (en) 1986-09-23
KR850002270A (ko) 1985-05-10

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