LU85476A1 - Nouveaux derives de coumarine,leurs procedes de preparation,compositions pharmaceutiques les contenant et methodes d'utilisation - Google Patents

Nouveaux derives de coumarine,leurs procedes de preparation,compositions pharmaceutiques les contenant et methodes d'utilisation Download PDF

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Publication number
LU85476A1
LU85476A1 LU85476A LU85476A LU85476A1 LU 85476 A1 LU85476 A1 LU 85476A1 LU 85476 A LU85476 A LU 85476A LU 85476 A LU85476 A LU 85476A LU 85476 A1 LU85476 A1 LU 85476A1
Authority
LU
Luxembourg
Prior art keywords
group
formula
hydroxy
methyl
carbon atoms
Prior art date
Application number
LU85476A
Other languages
English (en)
French (fr)
Inventor
Aurelio Romeo
Francesco Della Valle
Original Assignee
Fidia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Spa filed Critical Fidia Spa
Publication of LU85476A1 publication Critical patent/LU85476A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
LU85476A 1983-07-29 1984-07-24 Nouveaux derives de coumarine,leurs procedes de preparation,compositions pharmaceutiques les contenant et methodes d'utilisation LU85476A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8348791A IT1212882B (it) 1983-07-29 1983-07-29 Derivati basici della cumarina
IT4879183 1983-07-29

Publications (1)

Publication Number Publication Date
LU85476A1 true LU85476A1 (fr) 1984-12-06

Family

ID=11268572

Family Applications (1)

Application Number Title Priority Date Filing Date
LU85476A LU85476A1 (fr) 1983-07-29 1984-07-24 Nouveaux derives de coumarine,leurs procedes de preparation,compositions pharmaceutiques les contenant et methodes d'utilisation

Country Status (25)

Country Link
US (1) US4737517A (xx)
EP (1) EP0133766B1 (xx)
JP (1) JPS6054378A (xx)
KR (1) KR870001483B1 (xx)
AR (2) AR240816A1 (xx)
AT (1) ATE60329T1 (xx)
AU (1) AU581853B2 (xx)
BE (1) BE900225A (xx)
CH (1) CH662563A5 (xx)
DE (1) DE3483989D1 (xx)
DK (1) DK354784A (xx)
ES (4) ES534581A0 (xx)
FI (1) FI85269C (xx)
FR (1) FR2549832B1 (xx)
GR (1) GR82014B (xx)
HU (2) HUT36815A (xx)
IL (1) IL72515A (xx)
IN (1) IN161176B (xx)
IT (1) IT1212882B (xx)
LU (1) LU85476A1 (xx)
MX (1) MX162759A (xx)
NO (1) NO843042L (xx)
NZ (1) NZ209003A (xx)
PT (1) PT78986B (xx)
ZA (1) ZA845670B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990008529A2 (en) * 1989-01-23 1990-08-09 Lehigh University 7-alkoxycoumarins, dihydropsoralens, and benzodipyranones as photo-activated therapeutic agents and inhibitors of epidermal growth factor
US5356929A (en) * 1989-01-23 1994-10-18 Lehigh University Reduced and quaternized psoralens as photo-activated therapeutics
US6251644B1 (en) 1990-04-16 2001-06-26 Baxter International, Inc. Method for inactivating non-enveloped viral contaminants with a photosensitizer by increasing viral permeability to the photosensitizer
US5516629A (en) * 1990-04-16 1996-05-14 Cryopharm Corporation Photoinactivation of viral and bacterial blood contaminants using halogenated coumarins
US5484951A (en) * 1990-10-19 1996-01-16 Octamer, Incorporated 5-iodo-6-amino-6-nitroso-1,2-benzopyrones useful as cytostatic and antiviral agents
US5482975A (en) * 1991-10-22 1996-01-09 Octamer, Inc. Adenosine diphosphoribose polymerase binding nitroso aromatic compounds useful as retroviral inactivating agents, anti-retroviral agents and anti-tumor agents
US5877185A (en) * 1991-10-22 1999-03-02 Octamer, Inc. Synergistic compositions useful as anti-tumor agents
US5783599A (en) * 1993-02-24 1998-07-21 Octamer Inc Methods of treating cancer and viral infections with 5-iodo-6-amino-and 5-iodo-6-nitroso-1 2-benzopyrones
WO1994024119A1 (en) * 1993-04-13 1994-10-27 Morinaga Milk Industry Co., Ltd. Coumarin derivative and use thereof
DE10352535A1 (de) * 2003-11-07 2005-06-16 Steag Microparts Gmbh Mikrostrukturierte Trennvorrichtung und Verfahren zum Abtrennen von flüssigen Bestandteilen aus einer Partikel enthaltenden Flüssigkeit
US20050245489A1 (en) * 2004-05-03 2005-11-03 Pinney Kevin G Chromene-containing compounds with anti-tubulin and vascular targeting activity
US7456214B2 (en) * 2004-05-03 2008-11-25 Baylor University Chromene-containing compounds with anti-tubulin and vascular targeting activity
BRPI0404130A (pt) * 2004-09-20 2006-05-02 Univ Rio De Janeiro cumarinas substituìdas, processo de produção de tais cumarinas e composições contendo as mesmas
CN104529972B (zh) * 2014-10-10 2016-05-18 北京工业大学 蛋白激酶抑制剂香豆素及其制备方法和医药应用
KR102053748B1 (ko) 2017-12-20 2019-12-09 강원대학교산학협력단 쿠마린 유도체를 포함하는 알레르기성 염증성 질환의 예방 또는 치료용 약학 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3515721A (en) * 1967-06-26 1970-06-02 Cassella Farbwerke Mainkur Ag 3-tertiary-aminoethyl-4-methyl or phenyl-7-ethoxycarbonylmethoxy - halo or mononitro coumarins and congeners
BE761985A (fr) * 1970-10-19 1971-07-01 Recordati Chem Pharm Procede de preparation de n-alcoyl-dimethylamines
US3880885A (en) * 1971-11-23 1975-04-29 Sandoz Ag Tertiary aminoethyl isochromans and isocoumarins
IT1088554B (it) * 1977-11-17 1985-06-10 F I D I A Spa Procedimento sellettivo per la preparazione di derivati della 7-indrossi cumarina
IT1160366B (it) * 1978-12-19 1987-03-11 F I D I A Spa Applicazioni in campo farmacologico e terapeutico dell'8-cloro-3(beta-dietilamincetil)-4-metil-7-etossi-carbonilmetossi cumarina cloridrato preparato allo stato puro con procedimento selettivo con particolare riguardo alla sua attivita' anti-aggregante piastrinica
US4321270A (en) * 1981-01-29 1982-03-23 E. R. Squibb & Sons, Inc. Substituted chromans
CA1205028A (en) * 1981-07-01 1986-05-27 Jerald C. Hinshaw Fluorescent chelates and labeled specific binding reagents prepared therefrom

Also Published As

Publication number Publication date
DK354784A (da) 1985-01-30
IL72515A0 (en) 1984-11-30
EP0133766A2 (en) 1985-03-06
NZ209003A (en) 1988-04-29
PT78986A (pt) 1985-02-20
ES545240A0 (es) 1987-06-01
FI842997A (fi) 1985-01-31
ES8602739A1 (es) 1985-12-16
AR240926A2 (es) 1991-03-27
ATE60329T1 (de) 1991-02-15
FI85269C (fi) 1992-03-25
ES8700246A1 (es) 1986-11-16
ES534581A0 (es) 1985-12-16
HU199819B (en) 1990-03-28
IL72515A (en) 1992-05-25
ES8608503A1 (es) 1986-07-16
ZA845670B (en) 1985-03-27
NO843042L (no) 1985-01-30
HUT36815A (en) 1985-10-28
AU581853B2 (en) 1989-03-09
KR870001483B1 (ko) 1987-08-13
AR240926A1 (es) 1991-03-27
KR850001189A (ko) 1985-03-16
GR82014B (xx) 1984-12-12
AR240816A2 (es) 1991-02-28
EP0133766A3 (en) 1985-12-27
PT78986B (en) 1986-06-18
FR2549832A1 (fr) 1985-02-01
JPH0475911B2 (xx) 1992-12-02
AR240816A1 (es) 1991-02-28
ES545238A0 (es) 1986-11-16
ES545239A0 (es) 1986-07-16
FI842997A0 (fi) 1984-07-27
MX162759A (es) 1991-06-25
DE3483989D1 (de) 1991-02-28
DK354784D0 (da) 1984-07-19
IT8348791A0 (it) 1983-07-29
BE900225A (fr) 1985-01-28
ES8706139A1 (es) 1987-06-01
IT1212882B (it) 1989-11-30
JPS6054378A (ja) 1985-03-28
FR2549832B1 (fr) 1987-08-14
CH662563A5 (fr) 1987-10-15
EP0133766B1 (en) 1991-01-23
AU3127484A (en) 1985-01-31
IN161176B (xx) 1987-10-10
US4737517A (en) 1988-04-12
FI85269B (fi) 1991-12-13

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