LU79312A1 - Procede de preparation de nouvelles oximes derivees de l'acide 3-acetoxymethyl-7-amino thiazolyl acetamido cephalosporanique - Google Patents

Procede de preparation de nouvelles oximes derivees de l'acide 3-acetoxymethyl-7-amino thiazolyl acetamido cephalosporanique

Info

Publication number
LU79312A1
LU79312A1 LU79312A LU79312A LU79312A1 LU 79312 A1 LU79312 A1 LU 79312A1 LU 79312 A LU79312 A LU 79312A LU 79312 A LU79312 A LU 79312A LU 79312 A1 LU79312 A1 LU 79312A1
Authority
LU
Luxembourg
Prior art keywords
acetoxymethyl
preparation
amino thiazolyl
acetamido cephalosporanic
oximes derived
Prior art date
Application number
LU79312A
Other languages
English (en)
French (fr)
Inventor
R Heymes
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7708988A external-priority patent/FR2384782A1/fr
Priority claimed from FR7736512A external-priority patent/FR2421906A2/fr
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of LU79312A1 publication Critical patent/LU79312A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
LU79312A 1977-03-25 1978-03-24 Procede de preparation de nouvelles oximes derivees de l'acide 3-acetoxymethyl-7-amino thiazolyl acetamido cephalosporanique LU79312A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7708988A FR2384782A1 (fr) 1977-03-25 1977-03-25 Nouvelles oximes derivees de l'acide 3-acetoxymethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR7736512A FR2421906A2 (fr) 1977-12-05 1977-12-05 Nouvelles oximes derivees de l'acide 3-acetoxy methyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
LU79312A1 true LU79312A1 (fr) 1978-11-03

Family

ID=26219930

Family Applications (1)

Application Number Title Priority Date Filing Date
LU79312A LU79312A1 (fr) 1977-03-25 1978-03-24 Procede de preparation de nouvelles oximes derivees de l'acide 3-acetoxymethyl-7-amino thiazolyl acetamido cephalosporanique

Country Status (18)

Country Link
US (4) US4288434A (ru)
JP (2) JPS53119887A (ru)
AT (1) AT360153B (ru)
AU (1) AU520657B2 (ru)
CA (1) CA1125280A (ru)
CH (4) CH648555A5 (ru)
DE (2) DE2812625A1 (ru)
DK (1) DK159156C (ru)
ES (2) ES468169A1 (ru)
GB (2) GB1605175A (ru)
HU (1) HU182567B (ru)
IE (1) IE47361B1 (ru)
IT (1) IT1103478B (ru)
LU (1) LU79312A1 (ru)
NL (1) NL192041C (ru)
PH (1) PH15764A (ru)
PT (1) PT67815A (ru)
SE (2) SE439312B (ru)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE878514A (fr) * 1978-09-04 1980-02-29 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne
PH17188A (en) * 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
US4409217A (en) 1977-03-14 1983-10-11 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
SE439312B (sv) * 1977-03-25 1985-06-10 Roussel Uclaf Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra
FR2410655A1 (fr) * 1977-12-05 1979-06-29 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-substitue 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2432521A1 (fr) * 1978-03-31 1980-02-29 Roussel Uclaf Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2421907A1 (fr) * 1978-04-07 1979-11-02 Roussel Uclaf Nouvelles cephalosporines derivees de l'acide 7-/2-(2-amino 4-thiazolyl)2-(carboxymethoxyimino/acetamido 3-substitue cephalosporanique, leur procede de preparation et leur application comme medicaments
US4288435A (en) 1978-07-17 1981-09-08 Fujisawa Pharmaceutical Co., Ltd. 3,7-Disubstituted-3-cephem-4-carboxylic acid compounds and pharmaceutical antibacterial compositions containing them
US4284631A (en) 1978-07-31 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
US4372952A (en) 1978-07-31 1983-02-08 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4341775A (en) * 1978-09-11 1982-07-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
DE2945248A1 (de) * 1978-11-13 1980-05-22 Fujisawa Pharmaceutical Co Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel
US4237128A (en) 1979-04-12 1980-12-02 E. R. Squibb & Sons, Inc. 7-[2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1,1-dialkyl)alkoxyimino]acetamido]cephem sulfoxides
FR2466468A1 (fr) * 1979-10-02 1981-04-10 Glaxo Group Ltd Nouvelles cephalosporines, leur procede de preparation et leur application en therapeutique
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
US4252802A (en) * 1980-03-13 1981-02-24 E. R. Squibb & Sons, Inc. Hydroxamic acid derivatives of 7-[(2-amino-4-thiazolyl)-oximino] cephalosporins
GR76342B (ru) * 1981-02-02 1984-08-06 Fujisawa Pharmaceutical Co
EP0058250A3 (de) * 1981-02-17 1983-08-17 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Cephalosporinderivate, deren Herstellung und entsprechende pharmazeutische Präparate
IE53429B1 (en) * 1981-08-03 1988-11-09 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
US4493933A (en) * 1981-11-13 1985-01-15 Glaxo Group Limited Manufacture of antibiotics
JPS58135872A (ja) * 1981-11-13 1983-08-12 グラクソ・グル−プ・リミテツド 新規な化合物およびその製法
ATE30724T1 (de) 1982-06-28 1987-11-15 Bristol Myers Co Cephalosporinderivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen die sie enthalten.
EP0115770B2 (en) * 1983-01-07 1996-06-19 Takeda Chemical Industries, Ltd. Thiazole Derivatives
US4652651A (en) * 1983-05-31 1987-03-24 Hoffmann-La Roche Inc. Process for the manufacture of 1-sulpho-2-oxoazetidine carboxylic acid intermediates via catalytic ester cleavage
DE3485860T2 (de) * 1983-12-29 1993-01-14 Mochida Pharm Co Ltd Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.
AT381496B (de) * 1984-04-10 1986-10-27 Biochemie Gmbh Verfahren zur herstellung von cephalosporinantibiotika
US4610824A (en) * 1984-10-09 1986-09-09 E. R. Squibb & Sons, Inc. Hydrazide derivatives of monocyclic beta-lactam antibiotics
US4680409A (en) * 1984-10-09 1987-07-14 E. R. Squibb & Sons, Inc. Hydrazide containing derivatives of 2-amino-4-thiazole-acetic acid
US4840945A (en) * 1985-04-01 1989-06-20 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
US4647660A (en) * 1985-05-02 1987-03-03 E. R. Squibb & Sons, Inc. 3-acylamino-2-oxo-1-azetidinesulfonic acids
IL84128A (en) * 1986-10-13 1992-12-01 Eisai Co Ltd 3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them
CN1313452C (zh) * 2005-06-08 2007-05-02 浙江普洛化学有限公司 制备(z)－2－(2－氨基－4－噻唑)－2－羟基亚胺乙酸酯及其衍生物的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3971778A (en) * 1972-05-12 1976-07-27 Glaxo Laboratories Limited Cephalosporins having (α-etherified oximino)acylamido groups at the 7-position
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
GB1472534A (en) * 1973-07-06 1977-05-04 Glaxo Lab Ltd 7beta-hydroxyiminoacylamido-cephalosporins
CH617703A5 (en) * 1973-12-21 1980-06-13 Glaxo Operations Ltd Process for the preparation of the syn-isomer or of a mixture of syn- and anti-isomers of novel antibiotically active 7 beta -acylamino-ceph-3-em-4-carboxylic acids
US4095021A (en) * 1973-12-21 1978-06-13 Glaxo Laboratories Limited 3-Carbamoyloxymethyl or N-methyl-carbamoyloxymethyl-7-[2-carboxymethoxyimino-2-(fur-2-yl or thien-2-yl)acetamido]ceph-3-em-4-carboxylic acids and derivatives thereof
US4203899A (en) * 1974-12-19 1980-05-20 Takeda Chemical Industries, Ltd. Thiazolylacetamido compounds
DK154939C (da) 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
US4376203A (en) * 1976-01-23 1983-03-08 Roussell Uclaf Novel 3-acetoxymethyl-7-(iminoacetamido)-cephalosporanic acid derivatives
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
JPS6011713B2 (ja) * 1976-09-08 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
PH17188A (en) * 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
SE439312B (sv) * 1977-03-25 1985-06-10 Roussel Uclaf Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra

Also Published As

Publication number Publication date
SE8304239L (sv) 1983-08-02
JPS6237037B2 (ru) 1987-08-10
IE780604L (en) 1978-09-25
DE2812625C2 (ru) 1990-08-23
SE7802833L (sv) 1978-11-02
US4288434A (en) 1981-09-08
CH646159A5 (fr) 1984-11-15
US4386210A (en) 1983-05-31
IT7848604A0 (it) 1978-03-24
US4487937A (en) 1984-12-11
AU520657B2 (en) 1982-02-18
ATA218378A (de) 1980-05-15
CA1125280A (fr) 1982-06-08
PH15764A (en) 1983-03-24
DK129578A (da) 1978-09-26
DE2812625A1 (de) 1978-09-28
AU3447178A (en) 1979-09-27
NL192041C (nl) 1997-01-07
DE2858771C2 (ru) 1990-09-06
HU182567B (en) 1984-02-28
JPS53119887A (en) 1978-10-19
NL192041B (nl) 1996-09-02
SE453192B (sv) 1988-01-18
JPH0362711B2 (ru) 1991-09-26
NL7803166A (nl) 1978-09-27
IE47361B1 (en) 1984-03-07
SE8304239D0 (sv) 1983-08-02
AT360153B (de) 1980-12-29
ES477592A1 (es) 1979-08-01
IT1103478B (it) 1985-10-14
DK159156B (da) 1990-09-10
ES468169A1 (es) 1979-07-16
GB1605176A (en) 1982-11-17
DK159156C (da) 1991-02-11
US4483981A (en) 1984-11-20
CH633292A5 (fr) 1982-11-30
CH648555A5 (fr) 1985-03-29
CH639652A5 (fr) 1983-11-30
GB1605175A (en) 1982-11-17
SE439312B (sv) 1985-06-10
PT67815A (fr) 1978-04-01
JPS6425768A (en) 1989-01-27

Similar Documents

Publication Publication Date Title
LU79312A1 (fr) Procede de preparation de nouvelles oximes derivees de l'acide 3-acetoxymethyl-7-amino thiazolyl acetamido cephalosporanique
LU79216A1 (fr) Procede de preparation de nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique
PT66353A (fr) Procede de preparation de nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique
PT66099B (fr) Procede de preparation de nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique
RO75256A (ro) Procedeu pentru prepararea unor derivato ai acidului 1,2,3, tiadiazol-5-carboxilic
RO75757A (ro) Procedeu de purificare a compusilor vinilaromatici
LU79313A1 (fr) Procede de preparation de nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique
OA06016A (fr) Procédé de préparation d'une forme cristalline du sel de sodium d'un dérivé oximiné de l'acide 7- amino thiazolyl acétamido céphalosporanique.
BE863808A (fr) Procede de production de l'acide 5-methyltetrahydrofoliquded
BE872497A (fr) Nouvelles oximes derivees de l'acide 3-substitue 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et les compositions pharmaceutiques les renfermant
BE883909A (fr) Procede de preparation de chloro-2proprionate d'alcoyle par chloration de lactate d'alcoyle
PT69815A (fr) Procede de preparation de l' o-methallyloxyphenol
PT66944B (fr) Procede de preparation de nouvelles oximes derivees de l'acide 3-carbamoyloxymethyl 7-amino thiazolyl acetamido cephalosporanique
LU79080A1 (fr) Procede de preparation de nouvelles oximes derivees de 1'acide 3-thiadiazolyl thiomethyl 7-amino thiazolyl acetamido cephalosporanique
BE865298A (fr) Nouvelles oximes derivees de l'acide 3-acetoxy-methyl 7-amino thiazolyl acetamido cephalosporanique, procede de preparation et compositions pharmaceutiques
BE875378A (fr) Procede de preparation d'alcoylsilanes
PT69490A (fr) Procede de preparation de nouvelles oximes derivees de l'acide 3-azidomethyl 7-amino thiazolyl acetamido cephalosporanique
FR2279754A1 (fr) Procede de preparation de derives de l'acide 7-aminocephalosporanique
LU79998A1 (fr) Procede de preparation de nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamide cephalosporanique
RO74589A (ro) Procedeu de preparare a unor eteri oximici ai izonitrozocianecetamidei
OA05542A (fr) Procédé de préparation de nouvelles oximes dérivées de l'acide 7-amino thiazolyl acétamido céphalosporanique.
RO75093A (ro) Procedeu de preparare a acetonei din izobutiraldehida
FR2298552A1 (fr) Procede de preparation de derives d'acide 7-aminocephalosporanique
BE863860A (fr) Procede de preparation de l'alpha-naphtol
FR2304618A1 (fr) Procede de preparation d'oxydes d'hydroxyalkylphosphines