LT4989B - Apolipoproteino b-100 epitopo mimeziniai peptidai, jų konkatemerai ir modifikuotieji peptidai, ir juos turinti vakcinos kompozicija - Google Patents
Apolipoproteino b-100 epitopo mimeziniai peptidai, jų konkatemerai ir modifikuotieji peptidai, ir juos turinti vakcinos kompozicija Download PDFInfo
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- LT4989B LT4989B LT2002051A LT2002051A LT4989B LT 4989 B LT4989 B LT 4989B LT 2002051 A LT2002051 A LT 2002051A LT 2002051 A LT2002051 A LT 2002051A LT 4989 B LT4989 B LT 4989B
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- peptide
- mimetic
- concatemer
- peptides
- apoliprotein
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Obesity (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Child & Adolescent Psychology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20000052055 | 2000-09-04 | ||
| KR10-2001-0054005A KR100472841B1 (ko) | 2000-09-04 | 2001-09-04 | 아포지단백질 비-100의 에피토프에 대한 모조 펩타이드,그들의 연쇄물 또는 변형체와 이들을 함유하는 백신 조성물 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| LT2002051A LT2002051A (en) | 2002-09-25 |
| LT4989B true LT4989B (lt) | 2003-01-27 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LT2002051A LT4989B (lt) | 2000-09-04 | 2002-04-29 | Apolipoproteino b-100 epitopo mimeziniai peptidai, jų konkatemerai ir modifikuotieji peptidai, ir juos turinti vakcinos kompozicija |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6825318B2 (zh) |
| EP (1) | EP1315517B1 (zh) |
| JP (1) | JP2004508029A (zh) |
| CN (1) | CN1231262C (zh) |
| AU (1) | AU8628601A (zh) |
| BG (1) | BG106655A (zh) |
| BR (1) | BR0107175A (zh) |
| CA (1) | CA2389739A1 (zh) |
| CZ (1) | CZ20021571A3 (zh) |
| EE (1) | EE200200238A (zh) |
| HU (1) | HUP0203251A2 (zh) |
| IL (1) | IL149379A0 (zh) |
| LT (1) | LT4989B (zh) |
| MX (1) | MXPA02004505A (zh) |
| NO (1) | NO20022147D0 (zh) |
| RU (1) | RU2313536C2 (zh) |
| SK (1) | SK6312002A3 (zh) |
| WO (1) | WO2002020040A1 (zh) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| AU2004248192A1 (en) * | 2003-06-11 | 2004-12-23 | Schering Aktiengesellschaft | Novel modified corin molecules having substitute activation sequences and uses thereof |
| KR100639397B1 (ko) * | 2004-03-18 | 2006-10-26 | (주)에스제이바이오메드 | 항비만용 면역원성 하이브리드 폴리펩타이드 및 이를포함하는 항비만 백신 조성물 |
| US20070054298A1 (en) * | 2005-08-12 | 2007-03-08 | Kent Kirshenbaum | Methods for enzyme-mediated coupling of oligomers |
| WO2007075335A2 (en) * | 2005-12-16 | 2007-07-05 | The Regents Of The University Of California | Modulation of in utero immune programming |
| US8961982B2 (en) * | 2005-12-16 | 2015-02-24 | The Regents Of The University Of California | Modulation of developmental immune programming and protection against cardiovascular disease, diabetes, infectious diseases, and cancer |
| KR100956893B1 (ko) * | 2006-09-25 | 2010-05-11 | (주)에스제이바이오메드 | 항비만용 면역원성 하이브리드 폴리펩타이드 및 이를포함하는 항비만 백신 조성물 |
| CN103520713B (zh) * | 2013-10-16 | 2015-10-28 | 西北农林科技大学 | 一种ApoB100酵母重组疫苗及其制备方法和应用 |
| US10858422B2 (en) | 2016-05-31 | 2020-12-08 | Abcentra, Llc | Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody |
| US10434141B2 (en) | 2016-05-31 | 2019-10-08 | Abcentra, Llc | Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody |
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| CA2283474A1 (en) * | 1997-03-04 | 1998-09-11 | Bio-Technology General Corp. | Isolation of tissue specific peptide ligands and their use for targeting pharmaceuticals to organs |
| AU2801299A (en) * | 1998-03-04 | 1999-09-20 | Bio-Technology General Corporation | Isolation of tissue specific peptide ligands and their use for targeting pharmaceuticals to organs |
| BR0108924A (pt) * | 2000-03-03 | 2003-04-29 | Smithkline Beecham Biolog | Composição umonogênica adaptada para administração a um hospedeiro humano para o tratamento ou prevenção da aterosclerose, vacina, e, método de tratamento ou profilaxia da aterosclerose |
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2001
- 2001-09-04 EP EP01965715A patent/EP1315517B1/en not_active Expired - Lifetime
- 2001-09-04 AU AU86286/01A patent/AU8628601A/en not_active Abandoned
- 2001-09-04 IL IL14937901A patent/IL149379A0/xx unknown
- 2001-09-04 WO PCT/KR2001/001492 patent/WO2002020040A1/en not_active Application Discontinuation
- 2001-09-04 MX MXPA02004505A patent/MXPA02004505A/es unknown
- 2001-09-04 RU RU2003109439/13A patent/RU2313536C2/ru not_active IP Right Cessation
- 2001-09-04 HU HU0203251A patent/HUP0203251A2/hu unknown
- 2001-09-04 JP JP2002524523A patent/JP2004508029A/ja active Pending
- 2001-09-04 CN CNB018030572A patent/CN1231262C/zh not_active Expired - Fee Related
- 2001-09-04 SK SK631-2002A patent/SK6312002A3/sk unknown
- 2001-09-04 CZ CZ20021571A patent/CZ20021571A3/cs unknown
- 2001-09-04 CA CA002389739A patent/CA2389739A1/en not_active Abandoned
- 2001-09-04 BR BR0107175-0A patent/BR0107175A/pt not_active Application Discontinuation
- 2001-09-04 EE EEP200200238A patent/EE200200238A/xx unknown
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2002
- 2002-04-25 BG BG106655A patent/BG106655A/bg unknown
- 2002-04-29 LT LT2002051A patent/LT4989B/lt not_active IP Right Cessation
- 2002-05-03 NO NO20022147A patent/NO20022147D0/no not_active Application Discontinuation
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2003
- 2003-03-04 US US10/378,707 patent/US6825318B2/en not_active Expired - Lifetime
Non-Patent Citations (8)
| Title |
|---|
| ALVING CR, WASSEF NM, POTTER M.: "Antibodies to cholesterol: biological implications of antibodies to lipids", CURR TOP MICROBIOL IMMUNOL., 1996, pages 181 - 186, XP002923267 |
| BRECHER G, WAXLER SH.: "Obesity in albino mice due to single injections of goldthioglucose", PROC SOC EXP BIOL MED., 1949, pages 498 - 501 |
| BROWN MS, GOLDSTEIN JL: "Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis", ANNU REV BIOCHEM., 1983, pages 223 - 261 |
| CARL R. ALVING ET AL.: "Immunization with cholesterol-rich liposomes induces anti-cholesterol antibodies and reduces diet-induced hypercholesterolemia and plaque formation", JOURNAL OF LABORATORY AND CLINICAL MEDICINE, 1996, pages 40 - 49, XP001095396, DOI: doi:10.1016/S0022-2143(96)90164-X |
| CARL R. ALVING ET AL.: "Naturally occurring autoantibodies to cholesterol in humans", BIOCHEMICAL SOCIETY TRANSACTIONS, 1989, pages 637 - 639 |
| DALUM I ET AL.: "Induction of cross-reactive antibodies against a self protein by immunization with a modified self protein containing a foreign T helper epitope", MOL IMMUNOL., 1997, pages 1113 - 1120, XP002920190, DOI: doi:10.1016/S0161-5890(97)00147-8 |
| JM BAILEY: "Cholesterol vaccines", SCIENCE, 1994, pages 1067 - 1068, XP002310090 |
| W PALINSKI ET AL.: "Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis", PROC NATL ACAD SCI USA., 1995, pages 821 - 825, XP002951783, DOI: doi:10.1073/pnas.92.3.821 |
Also Published As
| Publication number | Publication date |
|---|---|
| BG106655A (bg) | 2004-08-31 |
| CA2389739A1 (en) | 2002-03-14 |
| NO20022147L (no) | 2002-05-03 |
| LT2002051A (en) | 2002-09-25 |
| HUP0203251A2 (hu) | 2003-01-28 |
| SK6312002A3 (en) | 2002-09-10 |
| EE200200238A (et) | 2003-06-16 |
| CZ20021571A3 (cs) | 2002-09-11 |
| CN1231262C (zh) | 2005-12-14 |
| NO20022147D0 (no) | 2002-05-03 |
| MXPA02004505A (es) | 2004-09-10 |
| US20030211997A1 (en) | 2003-11-13 |
| EP1315517A1 (en) | 2003-06-04 |
| WO2002020040A1 (en) | 2002-03-14 |
| EP1315517A4 (en) | 2005-02-09 |
| JP2004508029A (ja) | 2004-03-18 |
| BR0107175A (pt) | 2002-07-02 |
| AU8628601A (en) | 2002-03-22 |
| RU2313536C2 (ru) | 2007-12-27 |
| CN1392798A (zh) | 2003-01-22 |
| IL149379A0 (en) | 2002-11-10 |
| US6825318B2 (en) | 2004-11-30 |
| RU2003109439A (ru) | 2004-07-20 |
| EP1315517B1 (en) | 2010-10-20 |
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| Date | Code | Title | Description |
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| MM9A | Lapsed patents |
Effective date: 20030904 |