LT4800B - Aii antagonisto sulėtinto atpalaidavimo preparatas, jo gavimas ir panaudojimas - Google Patents
Aii antagonisto sulėtinto atpalaidavimo preparatas, jo gavimas ir panaudojimas Download PDFInfo
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- LT4800B LT4800B LT2000082A LT2000082A LT4800B LT 4800 B LT4800 B LT 4800B LT 2000082 A LT2000082 A LT 2000082A LT 2000082 A LT2000082 A LT 2000082A LT 4800 B LT4800 B LT 4800B
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- sustained release
- angiotensin
- acid
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- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 1
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- 125000003718 tetrahydrofuranyl group Chemical group 0.000 description 1
- 150000004044 tetrasaccharides Chemical class 0.000 description 1
- XWMXMWHHTIEXRE-UHFFFAOYSA-N thiadiazole 1-oxide Chemical group O=S1C=CN=N1 XWMXMWHHTIEXRE-UHFFFAOYSA-N 0.000 description 1
- 229910052723 transition metal Inorganic materials 0.000 description 1
- 150000003624 transition metals Chemical class 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 235000013337 tricalcium citrate Nutrition 0.000 description 1
- 150000003627 tricarboxylic acid derivatives Chemical class 0.000 description 1
- ITMCEJHCFYSIIV-UHFFFAOYSA-N triflic acid Chemical compound OS(=O)(=O)C(F)(F)F ITMCEJHCFYSIIV-UHFFFAOYSA-N 0.000 description 1
- PLSARIKBYIPYPF-UHFFFAOYSA-H trimagnesium dicitrate Chemical compound [Mg+2].[Mg+2].[Mg+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O PLSARIKBYIPYPF-UHFFFAOYSA-H 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
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- ACWBQPMHZXGDFX-QFIPXVFZSA-N valsartan Chemical compound C1=CC(CN(C(=O)CCCC)[C@@H](C(C)C)C(O)=O)=CC=C1C1=CC=CC=C1C1=NN=NN1 ACWBQPMHZXGDFX-QFIPXVFZSA-N 0.000 description 1
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- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
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- 239000011592 zinc chloride Substances 0.000 description 1
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- 229940118827 zinc phenolsulfonate Drugs 0.000 description 1
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 description 1
- 229910000368 zinc sulfate Inorganic materials 0.000 description 1
- 229960001763 zinc sulfate Drugs 0.000 description 1
- VRGNUPCISFMPEM-ZVGUSBNCSA-L zinc;(2r,3r)-2,3-dihydroxybutanedioate Chemical compound [Zn+2].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O VRGNUPCISFMPEM-ZVGUSBNCSA-L 0.000 description 1
- MCOGTQGPHPAUJN-UHFFFAOYSA-L zinc;2-hydroxyacetate Chemical compound [Zn+2].OCC([O-])=O.OCC([O-])=O MCOGTQGPHPAUJN-UHFFFAOYSA-L 0.000 description 1
- BOVNWDGXGNVNQD-UHFFFAOYSA-L zinc;2-hydroxybenzenesulfonate Chemical compound [Zn+2].OC1=CC=CC=C1S([O-])(=O)=O.OC1=CC=CC=C1S([O-])(=O)=O BOVNWDGXGNVNQD-UHFFFAOYSA-L 0.000 description 1
- JDLYKQWJXAQNNS-UHFFFAOYSA-L zinc;dibenzoate Chemical compound [Zn+2].[O-]C(=O)C1=CC=CC=C1.[O-]C(=O)C1=CC=CC=C1 JDLYKQWJXAQNNS-UHFFFAOYSA-L 0.000 description 1
- MLVWCBYTEFCFSG-UHFFFAOYSA-L zinc;dithiocyanate Chemical compound [Zn+2].[S-]C#N.[S-]C#N MLVWCBYTEFCFSG-UHFFFAOYSA-L 0.000 description 1
- FYGDTMLNYKFZSV-BYLHFPJWSA-N β-1,4-galactotrioside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@H](CO)O[C@@H](O[C@@H]2[C@@H](O[C@@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-BYLHFPJWSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5236698 | 1998-03-04 |
Publications (2)
Publication Number | Publication Date |
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LT2000082A LT2000082A (en) | 2001-03-26 |
LT4800B true LT4800B (lt) | 2001-06-25 |
Family
ID=12912818
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LT2000082A LT4800B (lt) | 1998-03-04 | 2000-08-31 | Aii antagonisto sulėtinto atpalaidavimo preparatas, jo gavimas ir panaudojimas |
Country Status (21)
Country | Link |
---|---|
US (2) | US6589547B1 (no) |
EP (1) | EP1058541B1 (no) |
KR (1) | KR20010086245A (no) |
CN (1) | CN1291888A (no) |
AT (1) | ATE258430T1 (no) |
AU (1) | AU2745199A (no) |
BR (1) | BR9908474A (no) |
CA (1) | CA2318446C (no) |
DE (1) | DE69914460T2 (no) |
EE (1) | EE200000499A (no) |
ES (1) | ES2214013T3 (no) |
HU (1) | HUP0101439A3 (no) |
ID (1) | ID25640A (no) |
IL (1) | IL137979A0 (no) |
LT (1) | LT4800B (no) |
LV (1) | LV12585B (no) |
NO (1) | NO20004350L (no) |
PL (1) | PL342684A1 (no) |
SK (1) | SK11902000A3 (no) |
WO (1) | WO1999044590A1 (no) |
ZA (1) | ZA991706B (no) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ID25640A (id) * | 1998-03-04 | 2000-10-19 | Takeda Chemical Industries Ltd | Preparat pelepasan terus menerus untuk antagonistik aii, produksi dan penggunaannya |
PT1197223E (pt) | 1999-04-28 | 2005-04-29 | Takeda Pharmaceutical | Preventivos/medicamentos/inibidores da progressao de retinopatia simples ou retinopatia pre-proliferativa |
SE9903028D0 (sv) * | 1999-08-27 | 1999-08-27 | Astra Ab | New use |
US6833381B2 (en) * | 2000-02-18 | 2004-12-21 | Takeda Chemical Industries, Ltd. | TNF-α inhibitors |
CA2400845A1 (en) * | 2000-02-21 | 2001-08-23 | Takeda Chemical Industries, Ltd. | Sustained-release preparation of physiologically active compound slightly soluble in water and production process and use of the same |
EP1312379A4 (en) * | 2000-08-25 | 2004-08-25 | Takeda Chemical Industries Ltd | FIBRINOGENIC REDUCTION AGENTS |
WO2002034263A1 (fr) * | 2000-10-25 | 2002-05-02 | Takeda Chemical Industries, Ltd. | Agents preventifs/remedes destines a l'hypertension portale |
WO2002074340A1 (fr) * | 2001-03-16 | 2002-09-26 | Takeda Chemical Industries, Ltd. | Procede de fabrication d'une preparation a liberation continue |
CA2456034A1 (en) * | 2001-08-03 | 2003-02-20 | Takeda Chemical Industries, Ltd. | Sustained-release medicines |
BRPI0105509B8 (pt) * | 2001-11-05 | 2021-05-25 | Univ Minas Gerais | formulações do peptídeo angiotensina-(1-7) usando as ciclodextrinas, lipossomas e o polímero plga |
WO2003041739A1 (en) | 2001-11-13 | 2003-05-22 | Takeda Chemical Industries, Ltd. | Anticaner agents |
EP1452176A4 (en) * | 2001-12-03 | 2009-01-21 | Takeda Pharmaceutical | MEANS FOR IMPROVING INSULIN RESISTANCE |
US7407778B2 (en) * | 2002-02-07 | 2008-08-05 | Pettegrew Jay W | Compounds, compositions and methods for treating neuropsychiatric disorders |
US7700074B2 (en) * | 2002-02-07 | 2010-04-20 | Pettegrew Jay W | Method and system for diagnosis of neuropsychiatric disorders including chronic alcoholism |
EP1579872B8 (en) * | 2002-12-27 | 2012-11-07 | Takeda Pharmaceutical Company Limited | Body weight gain inhibitor |
US20050038093A1 (en) * | 2003-05-02 | 2005-02-17 | Boehringer Ingelheim International Gmbh | Treating diabetic retinopathy with angiotensin II receptor blockers |
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Also Published As
Publication number | Publication date |
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US7294344B2 (en) | 2007-11-13 |
US20030198676A1 (en) | 2003-10-23 |
ES2214013T3 (es) | 2004-09-01 |
WO1999044590A1 (en) | 1999-09-10 |
EP1058541B1 (en) | 2004-01-28 |
KR20010086245A (ko) | 2001-09-10 |
PL342684A1 (en) | 2001-07-02 |
CN1291888A (zh) | 2001-04-18 |
DE69914460D1 (de) | 2004-03-04 |
NO20004350L (no) | 2000-10-03 |
LV12585A (en) | 2000-12-20 |
LT2000082A (en) | 2001-03-26 |
CA2318446A1 (en) | 1999-09-10 |
IL137979A0 (en) | 2001-10-31 |
LV12585B (en) | 2001-03-20 |
BR9908474A (pt) | 2000-12-05 |
US6589547B1 (en) | 2003-07-08 |
HUP0101439A2 (hu) | 2001-10-28 |
SK11902000A3 (sk) | 2001-02-12 |
CA2318446C (en) | 2008-09-23 |
HUP0101439A3 (en) | 2002-09-30 |
ATE258430T1 (de) | 2004-02-15 |
NO20004350D0 (no) | 2000-09-01 |
AU2745199A (en) | 1999-09-20 |
ZA991706B (en) | 2000-10-03 |
DE69914460T2 (de) | 2004-10-28 |
ID25640A (id) | 2000-10-19 |
EE200000499A (et) | 2002-02-15 |
EP1058541A1 (en) | 2000-12-13 |
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