LT3840837T - Arginazės inhibitoriai ir jų panaudojimo būdai - Google Patents

Arginazės inhibitoriai ir jų panaudojimo būdai

Info

Publication number
LT3840837T
LT3840837T LTEPPCT/EP2019/072341T LTEP2019072341T LT3840837T LT 3840837 T LT3840837 T LT 3840837T LT EP2019072341 T LTEP2019072341 T LT EP2019072341T LT 3840837 T LT3840837 T LT 3840837T
Authority
LT
Lithuania
Prior art keywords
methods
arginase inhibitors
arginase
inhibitors
Prior art date
Application number
LTEPPCT/EP2019/072341T
Other languages
English (en)
Lithuanian (lt)
Inventor
Dedong Wu
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of LT3840837T publication Critical patent/LT3840837T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/22Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
LTEPPCT/EP2019/072341T 2018-08-22 2019-08-21 Arginazės inhibitoriai ir jų panaudojimo būdai LT3840837T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862721113P 2018-08-22 2018-08-22
PCT/EP2019/072341 WO2020038983A1 (en) 2018-08-22 2019-08-21 Arginase inhibitors and methods of use thereof

Publications (1)

Publication Number Publication Date
LT3840837T true LT3840837T (lt) 2024-06-10

Family

ID=67742403

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/EP2019/072341T LT3840837T (lt) 2018-08-22 2019-08-21 Arginazės inhibitoriai ir jų panaudojimo būdai

Country Status (25)

Country Link
US (1) US11952392B2 (https=)
EP (2) EP4371614A3 (https=)
JP (1) JP7441210B2 (https=)
KR (1) KR102668252B1 (https=)
CN (1) CN112584900B (https=)
AU (1) AU2019323663B2 (https=)
CA (1) CA3109100A1 (https=)
CL (1) CL2021000430A1 (https=)
DK (1) DK3840837T3 (https=)
EA (1) EA202190532A1 (https=)
ES (1) ES2980252T3 (https=)
FI (1) FI3840837T3 (https=)
HR (1) HRP20240694T1 (https=)
HU (1) HUE066903T2 (https=)
IL (1) IL280924B2 (https=)
LT (1) LT3840837T (https=)
MA (1) MA53427B1 (https=)
MX (1) MX2021002042A (https=)
PL (1) PL3840837T3 (https=)
PT (1) PT3840837T (https=)
RS (1) RS65608B1 (https=)
SG (1) SG11202101618PA (https=)
SI (1) SI3840837T1 (https=)
SM (1) SMT202400221T1 (https=)
WO (1) WO2020038983A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI877770B (zh) 2018-02-27 2025-03-21 美商英塞特公司 作為a2a / a2b抑制劑之咪唑并嘧啶及三唑并嘧啶
EP3810610A1 (en) 2018-05-18 2021-04-28 Incyte Corporation Fused pyrimidine derivatives as a2a / a2b inhibitors
WO2020010197A1 (en) 2018-07-05 2020-01-09 Incyte Corporation Fused pyrazine derivatives as a2a / a2b inhibitors
TWI829857B (zh) 2019-01-29 2024-01-21 美商英塞特公司 作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶
PH12021551902A1 (en) * 2019-02-08 2022-08-01 Astrazeneca Ab Arginase inhibitors and methods of use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201503168VA (en) * 2010-04-22 2015-06-29 Mars Inc Inhibitors of arginase and their therapeutic applications
US10143699B2 (en) * 2015-06-23 2018-12-04 Calithera Biosciences, Inc. Compositions and methods for inhibiting arginase activity
JP2020502259A (ja) * 2016-11-08 2020-01-23 カリセラ バイオサイエンシズ,インコーポレイテッド アルギナーゼ阻害剤併用療法
CN114989205A (zh) 2016-12-22 2022-09-02 卡里塞拉生物科学股份公司 用于抑制精氨酸酶活性的组合物和方法
CN117186134A (zh) 2018-02-17 2023-12-08 阿斯利康(瑞典)有限公司 精氨酸酶抑制剂及其使用方法
EP3765006A4 (en) 2018-03-13 2022-02-23 Merck Sharp & Dohme Corp. ARGINASE INHIBITORS AND METHODS OF USE
CN111770756B (zh) 2018-04-27 2023-03-31 四川科伦博泰生物医药股份有限公司 非天然氨基酸类衍生物、包含其的药物组合物及其制备方法和用途

Also Published As

Publication number Publication date
KR102668252B1 (ko) 2024-05-21
CL2021000430A1 (es) 2021-09-03
EP4371614A2 (en) 2024-05-22
JP2021535111A (ja) 2021-12-16
EP3840837B1 (en) 2024-03-20
HUE066903T2 (hu) 2024-09-28
MA53427B1 (fr) 2024-06-28
KR20210049120A (ko) 2021-05-04
AU2019323663B2 (en) 2022-07-14
MX2021002042A (es) 2021-04-28
SMT202400221T1 (it) 2024-07-09
IL280924B1 (en) 2024-06-01
PL3840837T3 (pl) 2024-08-19
IL280924B2 (en) 2024-10-01
IL280924A (en) 2021-04-29
US20210332068A1 (en) 2021-10-28
ES2980252T3 (es) 2024-09-30
PT3840837T (pt) 2024-06-14
FI3840837T3 (fi) 2024-06-03
SG11202101618PA (en) 2021-03-30
US11952392B2 (en) 2024-04-09
JP7441210B2 (ja) 2024-02-29
EP4371614A3 (en) 2025-09-24
CN112584900A (zh) 2021-03-30
AU2019323663A1 (en) 2021-04-08
EP3840837A1 (en) 2021-06-30
WO2020038983A1 (en) 2020-02-27
SI3840837T1 (sl) 2024-07-31
RS65608B1 (sr) 2024-07-31
CA3109100A1 (en) 2020-02-27
HRP20240694T1 (hr) 2024-08-16
MA53427A (fr) 2021-12-01
EA202190532A1 (ru) 2021-07-08
CN112584900B (zh) 2025-07-15
DK3840837T3 (da) 2024-06-10

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