LT3840837T - Arginazės inhibitoriai ir jų panaudojimo būdai - Google Patents
Arginazės inhibitoriai ir jų panaudojimo būdaiInfo
- Publication number
- LT3840837T LT3840837T LTEPPCT/EP2019/072341T LTEP2019072341T LT3840837T LT 3840837 T LT3840837 T LT 3840837T LT EP2019072341 T LTEP2019072341 T LT EP2019072341T LT 3840837 T LT3840837 T LT 3840837T
- Authority
- LT
- Lithuania
- Prior art keywords
- methods
- arginase inhibitors
- arginase
- inhibitors
- Prior art date
Links
- 102000004452 Arginase Human genes 0.000 title 1
- 108700024123 Arginases Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/22—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862721113P | 2018-08-22 | 2018-08-22 | |
| PCT/EP2019/072341 WO2020038983A1 (en) | 2018-08-22 | 2019-08-21 | Arginase inhibitors and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT3840837T true LT3840837T (lt) | 2024-06-10 |
Family
ID=67742403
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEPPCT/EP2019/072341T LT3840837T (lt) | 2018-08-22 | 2019-08-21 | Arginazės inhibitoriai ir jų panaudojimo būdai |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US11952392B2 (lt) |
| EP (2) | EP3840837B1 (lt) |
| JP (1) | JP7441210B2 (lt) |
| KR (1) | KR102668252B1 (lt) |
| CN (1) | CN112584900A (lt) |
| AU (1) | AU2019323663B2 (lt) |
| CA (1) | CA3109100A1 (lt) |
| CL (1) | CL2021000430A1 (lt) |
| DK (1) | DK3840837T3 (lt) |
| EA (1) | EA202190532A1 (lt) |
| ES (1) | ES2980252T3 (lt) |
| FI (1) | FI3840837T3 (lt) |
| HR (1) | HRP20240694T1 (lt) |
| HU (1) | HUE066903T2 (lt) |
| IL (1) | IL280924B2 (lt) |
| LT (1) | LT3840837T (lt) |
| MA (1) | MA53427A (lt) |
| MX (1) | MX2021002042A (lt) |
| PL (1) | PL3840837T3 (lt) |
| PT (1) | PT3840837T (lt) |
| RS (1) | RS65608B1 (lt) |
| SG (1) | SG11202101618PA (lt) |
| SI (1) | SI3840837T1 (lt) |
| WO (1) | WO2020038983A1 (lt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112384515A (zh) | 2018-02-27 | 2021-02-19 | 因赛特公司 | 作为a2a/a2b抑制剂的咪唑并嘧啶和三唑并嘧啶 |
| JP7391046B2 (ja) | 2018-05-18 | 2023-12-04 | インサイト・コーポレイション | Ａ２ａ／ａ２ｂ阻害剤としての縮合ピリミジン誘導体 |
| EP3818063A1 (en) | 2018-07-05 | 2021-05-12 | Incyte Corporation | Fused pyrazine derivatives as a2a / a2b inhibitors |
| TWI829857B (zh) | 2019-01-29 | 2024-01-21 | 美商英塞特公司 | 作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶 |
| MA56324B1 (fr) * | 2019-02-08 | 2023-10-31 | Astrazeneca Ab 151 85 Soedertaelje | Inhibiteurs de l'arginase et leurs procédés d'utilisation |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103068830B (zh) * | 2010-04-22 | 2016-06-29 | 马尔斯公司 | 精氨酸酶抑制剂及其治疗应用 |
| WO2016210106A1 (en) * | 2015-06-23 | 2016-12-29 | Calithera Biosciences, Inc. | Compositions and methods for inhibiting arginase activity |
| WO2018089490A1 (en) * | 2016-11-08 | 2018-05-17 | Calithera Biosciences, Inc. | Arginase inhibitor combination therapies |
| PT3559009T (pt) | 2016-12-22 | 2021-05-04 | Calithera Biosciences Inc | Composições e métodos para inibir a atividade da arginase |
| WO2019159120A1 (en) | 2018-02-17 | 2019-08-22 | Astrazeneca Ab | Arginase inhibitors and methods of use thereof |
| EP3765006A4 (en) | 2018-03-13 | 2022-02-23 | Merck Sharp & Dohme Corp. | ARGINASE INHIBITORS AND METHODS OF USE |
| CN111770756B (zh) | 2018-04-27 | 2023-03-31 | 四川科伦博泰生物医药股份有限公司 | 非天然氨基酸类衍生物、包含其的药物组合物及其制备方法和用途 |
-
2019
- 2019-08-21 PT PT197586837T patent/PT3840837T/pt unknown
- 2019-08-21 DK DK19758683.7T patent/DK3840837T3/da active
- 2019-08-21 HR HRP20240694TT patent/HRP20240694T1/hr unknown
- 2019-08-21 EA EA202190532A patent/EA202190532A1/ru unknown
- 2019-08-21 EP EP19758683.7A patent/EP3840837B1/en active Active
- 2019-08-21 HU HUE19758683A patent/HUE066903T2/hu unknown
- 2019-08-21 KR KR1020217007915A patent/KR102668252B1/ko active IP Right Grant
- 2019-08-21 RS RS20240642A patent/RS65608B1/sr unknown
- 2019-08-21 EP EP24162089.7A patent/EP4371614A2/en active Pending
- 2019-08-21 AU AU2019323663A patent/AU2019323663B2/en active Active
- 2019-08-21 ES ES19758683T patent/ES2980252T3/es active Active
- 2019-08-21 LT LTEPPCT/EP2019/072341T patent/LT3840837T/lt unknown
- 2019-08-21 JP JP2021509794A patent/JP7441210B2/ja active Active
- 2019-08-21 SI SI201930758T patent/SI3840837T1/sl unknown
- 2019-08-21 FI FIEP19758683.7T patent/FI3840837T3/fi active
- 2019-08-21 WO PCT/EP2019/072341 patent/WO2020038983A1/en active Application Filing
- 2019-08-21 CA CA3109100A patent/CA3109100A1/en active Pending
- 2019-08-21 PL PL19758683.7T patent/PL3840837T3/pl unknown
- 2019-08-21 MX MX2021002042A patent/MX2021002042A/es unknown
- 2019-08-21 IL IL280924A patent/IL280924B2/en unknown
- 2019-08-21 CN CN201980055111.3A patent/CN112584900A/zh active Pending
- 2019-08-21 US US17/269,569 patent/US11952392B2/en active Active
- 2019-08-21 SG SG11202101618PA patent/SG11202101618PA/en unknown
- 2019-08-21 MA MA053427A patent/MA53427A/fr unknown
-
2021
- 2021-02-19 CL CL2021000430A patent/CL2021000430A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR102668252B1 (ko) | 2024-05-21 |
| EA202190532A1 (ru) | 2021-07-08 |
| JP7441210B2 (ja) | 2024-02-29 |
| HRP20240694T1 (hr) | 2024-08-16 |
| AU2019323663B2 (en) | 2022-07-14 |
| CA3109100A1 (en) | 2020-02-27 |
| PL3840837T3 (pl) | 2024-08-19 |
| PT3840837T (pt) | 2024-06-14 |
| IL280924A (en) | 2021-04-29 |
| EP4371614A2 (en) | 2024-05-22 |
| KR20210049120A (ko) | 2021-05-04 |
| IL280924B1 (en) | 2024-06-01 |
| ES2980252T3 (es) | 2024-09-30 |
| IL280924B2 (en) | 2024-10-01 |
| US20210332068A1 (en) | 2021-10-28 |
| SG11202101618PA (en) | 2021-03-30 |
| RS65608B1 (sr) | 2024-07-31 |
| US11952392B2 (en) | 2024-04-09 |
| FI3840837T3 (fi) | 2024-06-03 |
| HUE066903T2 (hu) | 2024-09-28 |
| DK3840837T3 (da) | 2024-06-10 |
| CL2021000430A1 (es) | 2021-09-03 |
| EP3840837B1 (en) | 2024-03-20 |
| CN112584900A (zh) | 2021-03-30 |
| WO2020038983A1 (en) | 2020-02-27 |
| SI3840837T1 (sl) | 2024-07-31 |
| AU2019323663A1 (en) | 2021-04-08 |
| MA53427A (fr) | 2021-12-01 |
| MX2021002042A (es) | 2021-04-28 |
| JP2021535111A (ja) | 2021-12-16 |
| EP3840837A1 (en) | 2021-06-30 |
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