LT3515924T - Kristalinės formos - Google Patents

Kristalinės formos

Info

Publication number
LT3515924T
LT3515924T LTEPPCT/EP2017/073858T LT17073858T LT3515924T LT 3515924 T LT3515924 T LT 3515924T LT 17073858 T LT17073858 T LT 17073858T LT 3515924 T LT3515924 T LT 3515924T
Authority
LT
Lithuania
Prior art keywords
crystalline forms
crystalline
forms
Prior art date
Application number
LTEPPCT/EP2017/073858T
Other languages
English (en)
Lithuanian (lt)
Inventor
Daniel Leuenberger
Stefan Reber
Markus Von Raumer
Original Assignee
Idorsia Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idorsia Pharmaceuticals Ltd filed Critical Idorsia Pharmaceuticals Ltd
Publication of LT3515924T publication Critical patent/LT3515924T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
LTEPPCT/EP2017/073858T 2016-09-22 2017-09-21 Kristalinės formos LT3515924T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP2016072562 2016-09-22
PCT/EP2017/073858 WO2018055016A1 (en) 2016-09-22 2017-09-21 Crystalline forms

Publications (1)

Publication Number Publication Date
LT3515924T true LT3515924T (lt) 2022-03-10

Family

ID=59923448

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/EP2017/073858T LT3515924T (lt) 2016-09-22 2017-09-21 Kristalinės formos

Country Status (27)

Country Link
US (4) US10730896B2 (OSRAM)
EP (2) EP3515924B1 (OSRAM)
JP (1) JP7097369B2 (OSRAM)
KR (1) KR102552795B1 (OSRAM)
CN (1) CN109715639B (OSRAM)
AU (1) AU2017331930B2 (OSRAM)
CA (1) CA3037794A1 (OSRAM)
CL (1) CL2019000728A1 (OSRAM)
CY (1) CY1125052T1 (OSRAM)
DK (1) DK3515924T3 (OSRAM)
EA (1) EA201990723A1 (OSRAM)
ES (1) ES2908572T3 (OSRAM)
HR (1) HRP20220234T1 (OSRAM)
HU (1) HUE057772T2 (OSRAM)
IL (1) IL265445B2 (OSRAM)
LT (1) LT3515924T (OSRAM)
MA (1) MA46266B1 (OSRAM)
MX (1) MX381590B (OSRAM)
MY (1) MY193080A (OSRAM)
PH (1) PH12019500567B1 (OSRAM)
PL (1) PL3515924T3 (OSRAM)
PT (1) PT3515924T (OSRAM)
RS (1) RS62946B1 (OSRAM)
SI (1) SI3515924T1 (OSRAM)
TW (1) TWI752086B (OSRAM)
UA (1) UA124073C2 (OSRAM)
WO (1) WO2018055016A1 (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3515924T (pt) 2016-09-22 2022-03-11 Idorsia Pharmaceuticals Ltd Formas cristalinas
US11179390B2 (en) 2017-03-15 2021-11-23 Idorsia Pharmaceuticals Ltd Subcutaneous administration of a P2Y12 receptor antagonist
EP4181872B1 (en) 2020-07-15 2025-11-26 Viatris Asia Pacific Pte. Ltd. Aqueous pharmaceutical composition comprising a p2y12 receptor antagonist
MX2024000653A (es) 2021-07-13 2024-01-31 Idorsia Pharmaceuticals Ltd Un proceso para la sintesis de ester de butilo de acido 4-((r)-2-{[6-((s)-3-metoxi-pirrolidin-1-il)-2-fenil-pirimidin-4-c arbonil]-amino}-3-fosfono-propionil)-piperazin-1-carboxilico.

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5373586A (en) 1976-12-09 1978-06-30 Mitsubishi Chem Ind Ltd New penicillin derivatives
CA2020437A1 (en) 1989-07-05 1991-01-06 Yoshihide Fuse Cinnamamide derivative
DE60022508T2 (de) 1999-06-14 2006-06-08 Eli Lilly And Co., Indianapolis Inhibitoren von serin proteasen
US6861424B2 (en) 2001-06-06 2005-03-01 Schering Aktiengesellschaft Platelet adenosine diphosphate receptor antagonists
ES2348942T3 (es) 2002-12-11 2010-12-17 Bayer Schering Pharma Aktiengesellschaft Compuestos de 2-aminocarbonil-quinolina como antagonistas del receptor plaquetario de adenosin difosfato.
CA2521313A1 (en) 2003-04-09 2004-10-28 Wyeth Derivatives of 2-(8,9-dioxo-2,6-diazabicyclo(5.2.o)non-1(7)-3n-2-yl)-al kyl phosphonic acid and their use as n-methyl-d-aspartate (nmda) recetor antagonists
TW200640877A (en) 2005-04-28 2006-12-01 Actelion Pharmaceuticals Ltd Pyrimidine derivatives
WO2007046075A1 (en) 2005-10-21 2007-04-26 Actelion Pharmaceuticals Ltd Piperazine derivatives as antimalarial agents
CL2007002920A1 (es) 2006-10-13 2008-06-06 Actelion Pharmaceuticals Ltd Compuestos derivados de 2-aminocarbonilpiridina; composicion farmaceutica; y uso para el tratamiento de trastornos vasculares oclusivos.
AR063518A1 (es) 2006-10-25 2009-01-28 Actelion Pharmaceuticals Ltd Derivados 2-fenil-6-aminocarbonil-pirimidina; composicion farmaceutica; y su uso para tratar y/o prevenir enfermedades vasculares perifericas viscerales, hepaticas y renales, enfermedades cardiovasculares y enfermedades cerebrovasculares asociados con la agregacion de plaquetas, incluyendo trombosis
JP4785881B2 (ja) 2007-02-27 2011-10-05 大塚製薬株式会社 医薬
MX2009011089A (es) 2007-04-23 2009-10-30 Sanofi Aventis Derivados de quinolina-carboxamida en calidad de antagonistas de p2y12.
CN101868469B (zh) 2007-11-29 2014-04-02 埃科特莱茵药品有限公司 膦酸衍生物及其作为p2y12受体拮抗剂
WO2009080227A2 (en) 2007-12-26 2009-07-02 Sanofi-Aventis Pyrazole-carboxamide derivatives as p2y12 antagonists
WO2009080226A2 (en) 2007-12-26 2009-07-02 Sanofis-Aventis Heterocyclic pyrazole-carboxamides as p2y12 antagonists
AR071653A1 (es) 2008-04-11 2010-07-07 Actelion Pharmaceuticals Ltd Derivados 2-fenil-4-ciclopropil-pirimidina
AR071652A1 (es) 2008-04-11 2010-07-07 Actelion Pharmaceuticals Ltd Derivados 2- fenil-piridina substituidos
MA33260B1 (fr) 2009-04-08 2012-05-02 Actelion Pharmaceuticals Ltd 6-(3-azabicyclo[3.1.0.]hex-3-yl)-2-phenylpyrimidines
SG175297A1 (en) 2009-04-22 2011-12-29 Actelion Pharmaceuticals Ltd Thiazole derivatives and their use as p2y12 receptor antagonists
PT3515924T (pt) 2016-09-22 2022-03-11 Idorsia Pharmaceuticals Ltd Formas cristalinas
US11179390B2 (en) 2017-03-15 2021-11-23 Idorsia Pharmaceuticals Ltd Subcutaneous administration of a P2Y12 receptor antagonist
EP4181872B1 (en) 2020-07-15 2025-11-26 Viatris Asia Pacific Pte. Ltd. Aqueous pharmaceutical composition comprising a p2y12 receptor antagonist

Also Published As

Publication number Publication date
WO2018055016A1 (en) 2018-03-29
DK3515924T3 (da) 2022-03-21
US11365209B2 (en) 2022-06-21
MA46266B1 (fr) 2022-02-28
JP2019529553A (ja) 2019-10-17
RS62946B1 (sr) 2022-03-31
TW201813965A (zh) 2018-04-16
HRP20220234T1 (hr) 2022-05-13
KR102552795B1 (ko) 2023-07-06
IL265445A (en) 2019-05-30
PH12019500567B1 (en) 2024-01-31
MY193080A (en) 2022-09-26
EP3515924A1 (en) 2019-07-31
US20220275011A1 (en) 2022-09-01
EP3515924B1 (en) 2021-12-15
BR112019004845A2 (pt) 2019-06-04
MX381590B (es) 2025-03-12
AU2017331930B2 (en) 2021-07-15
CA3037794A1 (en) 2018-03-29
TWI752086B (zh) 2022-01-11
CY1125052T1 (el) 2024-02-16
US12227532B2 (en) 2025-02-18
PT3515924T (pt) 2022-03-11
MX2019003093A (es) 2019-07-18
AU2017331930A1 (en) 2019-03-07
HUE057772T2 (hu) 2022-06-28
CL2019000728A1 (es) 2019-07-05
SI3515924T1 (sl) 2022-04-29
EP3981774A1 (en) 2022-04-13
US20250163086A1 (en) 2025-05-22
UA124073C2 (uk) 2021-07-14
US10730896B2 (en) 2020-08-04
NZ750772A (en) 2023-10-27
MA46266A (fr) 2019-07-31
US20210009614A1 (en) 2021-01-14
US20200017534A1 (en) 2020-01-16
IL265445B2 (en) 2024-05-01
PL3515924T3 (pl) 2022-04-11
JP7097369B2 (ja) 2022-07-07
IL265445B1 (en) 2024-01-01
CN109715639A (zh) 2019-05-03
KR20190052704A (ko) 2019-05-16
EA201990723A1 (ru) 2019-10-31
ES2908572T3 (es) 2022-05-03
CN109715639B (zh) 2022-04-19
PH12019500567A1 (en) 2019-11-18

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