PL3630725T3 - Postać krystaliczna n-butylodeoksygalaktonojirymycyny - Google Patents

Postać krystaliczna n-butylodeoksygalaktonojirymycyny

Info

Publication number
PL3630725T3
PL3630725T3 PL18728624.0T PL18728624T PL3630725T3 PL 3630725 T3 PL3630725 T3 PL 3630725T3 PL 18728624 T PL18728624 T PL 18728624T PL 3630725 T3 PL3630725 T3 PL 3630725T3
Authority
PL
Poland
Prior art keywords
butyldeooxygalactonojirymycin
crystalline form
crystalline
Prior art date
Application number
PL18728624.0T
Other languages
English (en)
Inventor
Vitor Oliveira
Ivan POGORELIC
Jean-Paul Roduit
Original Assignee
Idorsia Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idorsia Pharmaceuticals Ltd filed Critical Idorsia Pharmaceuticals Ltd
Publication of PL3630725T3 publication Critical patent/PL3630725T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
PL18728624.0T 2017-06-01 2018-05-31 Postać krystaliczna n-butylodeoksygalaktonojirymycyny PL3630725T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP2017063287 2017-06-01
PCT/EP2018/064365 WO2018220131A1 (en) 2017-06-01 2018-05-31 Crystalline form of n-butyldeoxygalactonojirimycin

Publications (1)

Publication Number Publication Date
PL3630725T3 true PL3630725T3 (pl) 2026-03-23

Family

ID=62492649

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18728624.0T PL3630725T3 (pl) 2017-06-01 2018-05-31 Postać krystaliczna n-butylodeoksygalaktonojirymycyny

Country Status (27)

Country Link
US (2) US11306058B2 (pl)
EP (1) EP3630725B1 (pl)
JP (2) JP6937850B2 (pl)
KR (1) KR102612650B1 (pl)
CN (1) CN110799497A (pl)
AU (1) AU2018278247B2 (pl)
CA (1) CA3065147A1 (pl)
CL (1) CL2019003478A1 (pl)
DK (1) DK3630725T3 (pl)
EA (1) EA201992807A1 (pl)
ES (1) ES3059191T3 (pl)
FI (1) FI3630725T3 (pl)
HR (1) HRP20251697T1 (pl)
IL (1) IL270961B2 (pl)
LT (1) LT3630725T (pl)
MA (1) MA48944B1 (pl)
MX (1) MX2019014427A (pl)
MY (1) MY201196A (pl)
NZ (1) NZ760100A (pl)
PH (1) PH12019502635A1 (pl)
PL (1) PL3630725T3 (pl)
PT (1) PT3630725T (pl)
RS (1) RS67675B1 (pl)
SI (1) SI3630725T1 (pl)
TW (1) TWI770184B (pl)
UA (1) UA125938C2 (pl)
WO (1) WO2018220131A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS67675B1 (sr) * 2017-06-01 2026-02-27 Idorsia Pharmaceuticals Ltd Kristalni oblik n‐butildeoksigalaktonojirimicina
WO2021061701A1 (en) 2019-09-25 2021-04-01 Teva Pharmaceuticals International Gmbh Solid state forms of lucerastat salts and process for preparation thereof
WO2025017212A1 (en) 2023-07-20 2025-01-23 Katholieke Universiteit Leuven Udp-glucose ceramide glucosyltransferase synthase (ugcg) inhibitors in the treatment of cancer
TR2024011149A1 (tr) * 2024-08-23 2026-03-23 Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ Mi̇galastat i̇çeren kapsül formülasyonlari

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2086413A1 (en) * 1990-06-29 1991-12-30 Yohji Ezure Piperidine derivatives
US6291657B1 (en) * 1993-05-13 2001-09-18 Monsanto Company Deoxygalactonojirimycin derivatives
US6274597B1 (en) 1998-06-01 2001-08-14 Mount Sinai School Of Medicine Of New York University Method of enhancing lysosomal α-Galactosidase A
GB0100889D0 (en) 2001-01-12 2001-02-21 Oxford Glycosciences Uk Ltd Compounds
GB0229476D0 (en) * 2002-12-17 2003-01-22 Oxford Glycosciences Uk Ltd Novel process
FR2861991B1 (fr) * 2003-11-07 2008-01-18 Centre Nat Rech Scient Utilisation d'inhibiteurs de glucosidase pour une therapie de la mucoviscidose
US7884115B2 (en) 2004-09-28 2011-02-08 Allergan, Inc. Methods and compositions for the treatment of pain and other neurological conditions
AU2006247065B8 (en) 2005-05-17 2012-07-12 Amicus Therapeutics, Inc. A method for the treatment of Pompe disease using 1-deoxynojirimycin derivatives
CA2616537A1 (en) 2005-07-27 2007-02-01 University Of Florida Research Foundation, Inc. Small compounds that correct protein misfolding and uses thereof
AU2007241622A1 (en) 2006-04-24 2007-11-01 Academisch Medisch Centrum Improved treatment of cystic fibrosis
GB0712494D0 (en) 2007-06-27 2007-08-08 Isis Innovation Substrate reduction therapy
ITMI20122090A1 (it) * 2012-12-06 2014-06-07 Dipharma Francis Srl Sintesi di un inibitore delle glicosiltransferasi
RS67675B1 (sr) 2017-06-01 2026-02-27 Idorsia Pharmaceuticals Ltd Kristalni oblik n‐butildeoksigalaktonojirimicina

Also Published As

Publication number Publication date
IL270961B1 (en) 2024-11-01
PT3630725T (pt) 2026-01-27
TWI770184B (zh) 2022-07-11
KR102612650B1 (ko) 2023-12-11
JP2021185184A (ja) 2021-12-09
DK3630725T3 (da) 2026-02-09
MX2019014427A (es) 2020-02-05
HRP20251697T1 (hr) 2026-02-27
FI3630725T3 (fi) 2026-01-27
JP2020521796A (ja) 2020-07-27
JP7373529B2 (ja) 2023-11-02
SI3630725T1 (sl) 2026-01-30
AU2018278247B2 (en) 2022-07-28
CA3065147A1 (en) 2018-12-06
ES3059191T3 (en) 2026-03-19
JP6937850B2 (ja) 2021-09-22
TW201902876A (zh) 2019-01-16
PH12019502635A1 (en) 2020-07-13
IL270961B2 (en) 2025-03-01
CL2019003478A1 (es) 2020-06-05
BR112019025125A2 (pt) 2020-07-21
MA48944A (fr) 2020-04-08
US20200140385A1 (en) 2020-05-07
EP3630725B1 (en) 2025-10-29
LT3630725T (lt) 2026-01-12
WO2018220131A1 (en) 2018-12-06
CN110799497A (zh) 2020-02-14
US11306058B2 (en) 2022-04-19
EA201992807A1 (ru) 2020-05-20
US20220002245A1 (en) 2022-01-06
MA48944B1 (fr) 2025-12-31
IL270961A (en) 2020-01-30
KR20200011992A (ko) 2020-02-04
US11713297B2 (en) 2023-08-01
AU2018278247A1 (en) 2020-01-16
NZ760100A (en) 2026-03-27
EP3630725A1 (en) 2020-04-08
RS67675B1 (sr) 2026-02-27
MY201196A (en) 2024-02-09
UA125938C2 (uk) 2022-07-13

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