PL3630725T3 - Postać krystaliczna n-butylodeoksygalaktonojirymycyny - Google Patents

Postać krystaliczna n-butylodeoksygalaktonojirymycyny

Info

Publication number
PL3630725T3
PL3630725T3 PL18728624.0T PL18728624T PL3630725T3 PL 3630725 T3 PL3630725 T3 PL 3630725T3 PL 18728624 T PL18728624 T PL 18728624T PL 3630725 T3 PL3630725 T3 PL 3630725T3
Authority
PL
Poland
Prior art keywords
butyldeooxygalactonojirymycin
crystalline form
crystalline
Prior art date
Application number
PL18728624.0T
Other languages
English (en)
Inventor
Vitor Oliveira
Ivan POGORELIC
Jean-Paul Roduit
Original Assignee
Idorsia Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idorsia Pharmaceuticals Ltd filed Critical Idorsia Pharmaceuticals Ltd
Publication of PL3630725T3 publication Critical patent/PL3630725T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/46Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
PL18728624.0T 2017-06-01 2018-05-31 Postać krystaliczna n-butylodeoksygalaktonojirymycyny PL3630725T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP2017063287 2017-06-01
PCT/EP2018/064365 WO2018220131A1 (en) 2017-06-01 2018-05-31 Crystalline form of n-butyldeoxygalactonojirimycin

Publications (1)

Publication Number Publication Date
PL3630725T3 true PL3630725T3 (pl) 2026-03-23

Family

ID=62492649

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18728624.0T PL3630725T3 (pl) 2017-06-01 2018-05-31 Postać krystaliczna n-butylodeoksygalaktonojirymycyny

Country Status (26)

Country Link
US (2) US11306058B2 (pl)
EP (1) EP3630725B1 (pl)
JP (2) JP6937850B2 (pl)
KR (1) KR102612650B1 (pl)
CN (1) CN110799497A (pl)
AU (1) AU2018278247B2 (pl)
CA (1) CA3065147A1 (pl)
CL (1) CL2019003478A1 (pl)
DK (1) DK3630725T3 (pl)
EA (1) EA201992807A1 (pl)
ES (1) ES3059191T3 (pl)
FI (1) FI3630725T3 (pl)
HR (1) HRP20251697T1 (pl)
IL (1) IL270961B2 (pl)
LT (1) LT3630725T (pl)
MA (1) MA48944B1 (pl)
MX (1) MX2019014427A (pl)
MY (1) MY201196A (pl)
PH (1) PH12019502635A1 (pl)
PL (1) PL3630725T3 (pl)
PT (1) PT3630725T (pl)
RS (1) RS67675B1 (pl)
SI (1) SI3630725T1 (pl)
TW (1) TWI770184B (pl)
UA (1) UA125938C2 (pl)
WO (1) WO2018220131A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018278247B2 (en) * 2017-06-01 2022-07-28 Idorsia Pharmaceuticals Ltd Crystalline form of N-butyldeoxygalactonojirimycin
US20220411371A1 (en) * 2019-09-25 2022-12-29 Teva Pharmaceuticals International Gmbh Solid state forms of lucerastat and process for preparation thereof
WO2025017212A1 (en) 2023-07-20 2025-01-23 Katholieke Universiteit Leuven Udp-glucose ceramide glucosyltransferase synthase (ugcg) inhibitors in the treatment of cancer
WO2026043459A2 (en) * 2024-08-23 2026-02-26 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Capsule formulations comprising migalastat

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2086413A1 (en) * 1990-06-29 1991-12-30 Yohji Ezure Piperidine derivatives
US6291657B1 (en) 1993-05-13 2001-09-18 Monsanto Company Deoxygalactonojirimycin derivatives
US6274597B1 (en) 1998-06-01 2001-08-14 Mount Sinai School Of Medicine Of New York University Method of enhancing lysosomal α-Galactosidase A
GB0100889D0 (en) 2001-01-12 2001-02-21 Oxford Glycosciences Uk Ltd Compounds
GB0229476D0 (en) * 2002-12-17 2003-01-22 Oxford Glycosciences Uk Ltd Novel process
FR2861991B1 (fr) * 2003-11-07 2008-01-18 Centre Nat Rech Scient Utilisation d'inhibiteurs de glucosidase pour une therapie de la mucoviscidose
US7884115B2 (en) 2004-09-28 2011-02-08 Allergan, Inc. Methods and compositions for the treatment of pain and other neurological conditions
EP1896083B1 (en) 2005-05-17 2016-03-02 Amicus Therapeutics, Inc. A method for the treatment of pompe disease using 1-deoxynojirimycin and derivatives
CN101267779A (zh) 2005-07-27 2008-09-17 福罗里达大学研究基金会有限公司 使用热休克治疗眼睛疾病
AU2007241622A1 (en) 2006-04-24 2007-11-01 Academisch Medisch Centrum Improved treatment of cystic fibrosis
GB0712494D0 (en) 2007-06-27 2007-08-08 Isis Innovation Substrate reduction therapy
ITMI20122090A1 (it) * 2012-12-06 2014-06-07 Dipharma Francis Srl Sintesi di un inibitore delle glicosiltransferasi
AU2018278247B2 (en) 2017-06-01 2022-07-28 Idorsia Pharmaceuticals Ltd Crystalline form of N-butyldeoxygalactonojirimycin

Also Published As

Publication number Publication date
PH12019502635A1 (en) 2020-07-13
KR102612650B1 (ko) 2023-12-11
DK3630725T3 (da) 2026-02-09
EA201992807A1 (ru) 2020-05-20
US20220002245A1 (en) 2022-01-06
MX2019014427A (es) 2020-02-05
MA48944B1 (fr) 2025-12-31
ES3059191T3 (en) 2026-03-19
JP2020521796A (ja) 2020-07-27
MA48944A (fr) 2020-04-08
TWI770184B (zh) 2022-07-11
FI3630725T3 (fi) 2026-01-27
AU2018278247A1 (en) 2020-01-16
CL2019003478A1 (es) 2020-06-05
MY201196A (en) 2024-02-09
EP3630725A1 (en) 2020-04-08
JP7373529B2 (ja) 2023-11-02
EP3630725B1 (en) 2025-10-29
UA125938C2 (uk) 2022-07-13
TW201902876A (zh) 2019-01-16
IL270961B1 (en) 2024-11-01
WO2018220131A1 (en) 2018-12-06
HRP20251697T1 (hr) 2026-02-27
LT3630725T (lt) 2026-01-12
IL270961A (en) 2020-01-30
KR20200011992A (ko) 2020-02-04
SI3630725T1 (sl) 2026-01-30
RS67675B1 (sr) 2026-02-27
US11713297B2 (en) 2023-08-01
IL270961B2 (en) 2025-03-01
US20200140385A1 (en) 2020-05-07
PT3630725T (pt) 2026-01-27
BR112019025125A2 (pt) 2020-07-21
CA3065147A1 (en) 2018-12-06
AU2018278247B2 (en) 2022-07-28
JP2021185184A (ja) 2021-12-09
CN110799497A (zh) 2020-02-14
JP6937850B2 (ja) 2021-09-22
US11306058B2 (en) 2022-04-19

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