DK3630725T3 - Krystallinsk form af n-butyldeoxygalactonojirimycin - Google Patents
Krystallinsk form af n-butyldeoxygalactonojirimycinInfo
- Publication number
- DK3630725T3 DK3630725T3 DK18728624.0T DK18728624T DK3630725T3 DK 3630725 T3 DK3630725 T3 DK 3630725T3 DK 18728624 T DK18728624 T DK 18728624T DK 3630725 T3 DK3630725 T3 DK 3630725T3
- Authority
- DK
- Denmark
- Prior art keywords
- butyldeoxygalactonojirimycin
- crystalline form
- crystalline
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP2017063287 | 2017-06-01 | ||
| PCT/EP2018/064365 WO2018220131A1 (en) | 2017-06-01 | 2018-05-31 | Crystalline form of n-butyldeoxygalactonojirimycin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3630725T3 true DK3630725T3 (da) | 2026-02-09 |
Family
ID=62492649
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18728624.0T DK3630725T3 (da) | 2017-06-01 | 2018-05-31 | Krystallinsk form af n-butyldeoxygalactonojirimycin |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US11306058B2 (da) |
| EP (1) | EP3630725B1 (da) |
| JP (2) | JP6937850B2 (da) |
| KR (1) | KR102612650B1 (da) |
| CN (1) | CN110799497A (da) |
| AU (1) | AU2018278247B2 (da) |
| CA (1) | CA3065147A1 (da) |
| CL (1) | CL2019003478A1 (da) |
| DK (1) | DK3630725T3 (da) |
| EA (1) | EA201992807A1 (da) |
| FI (1) | FI3630725T3 (da) |
| HR (1) | HRP20251697T1 (da) |
| IL (1) | IL270961B2 (da) |
| LT (1) | LT3630725T (da) |
| MA (1) | MA48944B1 (da) |
| MX (1) | MX2019014427A (da) |
| MY (1) | MY201196A (da) |
| PH (1) | PH12019502635A1 (da) |
| PT (1) | PT3630725T (da) |
| RS (1) | RS67675B1 (da) |
| SI (1) | SI3630725T1 (da) |
| TW (1) | TWI770184B (da) |
| UA (1) | UA125938C2 (da) |
| WO (1) | WO2018220131A1 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3630725T3 (da) * | 2017-06-01 | 2026-02-09 | Idorsia Pharmaceuticals Ltd | Krystallinsk form af n-butyldeoxygalactonojirimycin |
| WO2021061701A1 (en) | 2019-09-25 | 2021-04-01 | Teva Pharmaceuticals International Gmbh | Solid state forms of lucerastat salts and process for preparation thereof |
| WO2025017212A1 (en) | 2023-07-20 | 2025-01-23 | Katholieke Universiteit Leuven | Udp-glucose ceramide glucosyltransferase synthase (ugcg) inhibitors in the treatment of cancer |
| WO2026043459A2 (en) * | 2024-08-23 | 2026-02-26 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Capsule formulations comprising migalastat |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992000277A1 (en) * | 1990-06-29 | 1992-01-09 | Nippon Shinyaku Co., Ltd. | Piperidine derivative |
| US6291657B1 (en) | 1993-05-13 | 2001-09-18 | Monsanto Company | Deoxygalactonojirimycin derivatives |
| US6274597B1 (en) | 1998-06-01 | 2001-08-14 | Mount Sinai School Of Medicine Of New York University | Method of enhancing lysosomal α-Galactosidase A |
| GB0100889D0 (en) | 2001-01-12 | 2001-02-21 | Oxford Glycosciences Uk Ltd | Compounds |
| GB0229476D0 (en) | 2002-12-17 | 2003-01-22 | Oxford Glycosciences Uk Ltd | Novel process |
| FR2861991B1 (fr) * | 2003-11-07 | 2008-01-18 | Centre Nat Rech Scient | Utilisation d'inhibiteurs de glucosidase pour une therapie de la mucoviscidose |
| WO2006037069A1 (en) | 2004-09-28 | 2006-04-06 | Allergan, Inc. | Compositions comprising nb-dnj, ne-dnj or d-glucaro-delta-lactam and their uses for the treatment of pain and other neurological conditions |
| EP3782655A1 (en) | 2005-05-17 | 2021-02-24 | Amicus Therapeutics, Inc. | A method for the treatment of pompe disease using 1-deoxynojirimycin and derivatives |
| AU2006272497B2 (en) | 2005-07-27 | 2012-07-19 | University Of Florida Research Foundation, Inc. | Small compounds that correct protein misfolding and uses thereof |
| ATE479696T1 (de) | 2006-04-24 | 2010-09-15 | Amc Amsterdam | Verbessertes verfahren zur behandlung von cystischer fibrose |
| GB0712494D0 (en) | 2007-06-27 | 2007-08-08 | Isis Innovation | Substrate reduction therapy |
| ITMI20122090A1 (it) * | 2012-12-06 | 2014-06-07 | Dipharma Francis Srl | Sintesi di un inibitore delle glicosiltransferasi |
| DK3630725T3 (da) * | 2017-06-01 | 2026-02-09 | Idorsia Pharmaceuticals Ltd | Krystallinsk form af n-butyldeoxygalactonojirimycin |
-
2018
- 2018-05-31 DK DK18728624.0T patent/DK3630725T3/da active
- 2018-05-31 MX MX2019014427A patent/MX2019014427A/es unknown
- 2018-05-31 UA UAA201912130A patent/UA125938C2/uk unknown
- 2018-05-31 MA MA48944A patent/MA48944B1/fr unknown
- 2018-05-31 KR KR1020197038894A patent/KR102612650B1/ko active Active
- 2018-05-31 TW TW107118696A patent/TWI770184B/zh active
- 2018-05-31 CA CA3065147A patent/CA3065147A1/en active Pending
- 2018-05-31 EP EP18728624.0A patent/EP3630725B1/en active Active
- 2018-05-31 PT PT187286240T patent/PT3630725T/pt unknown
- 2018-05-31 IL IL270961A patent/IL270961B2/en unknown
- 2018-05-31 RS RS20260062A patent/RS67675B1/sr unknown
- 2018-05-31 FI FIEP18728624.0T patent/FI3630725T3/fi active
- 2018-05-31 WO PCT/EP2018/064365 patent/WO2018220131A1/en not_active Ceased
- 2018-05-31 HR HRP20251697TT patent/HRP20251697T1/hr unknown
- 2018-05-31 AU AU2018278247A patent/AU2018278247B2/en active Active
- 2018-05-31 CN CN201880035373.9A patent/CN110799497A/zh active Pending
- 2018-05-31 LT LTEPPCT/EP2018/064365T patent/LT3630725T/lt unknown
- 2018-05-31 SI SI201831279T patent/SI3630725T1/sl unknown
- 2018-05-31 JP JP2019566190A patent/JP6937850B2/ja active Active
- 2018-05-31 MY MYPI2019007035A patent/MY201196A/en unknown
- 2018-05-31 US US16/618,036 patent/US11306058B2/en active Active
- 2018-05-31 EA EA201992807A patent/EA201992807A1/ru unknown
-
2019
- 2019-11-22 PH PH12019502635A patent/PH12019502635A1/en unknown
- 2019-11-28 CL CL2019003478A patent/CL2019003478A1/es unknown
-
2021
- 2021-08-31 JP JP2021140904A patent/JP7373529B2/ja active Active
- 2021-09-20 US US17/479,341 patent/US11713297B2/en active Active
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