LT3262932T - Pelės su genetiškai modifikuotu pagrindiniu histosuderinamumo kompleksu - Google Patents

Pelės su genetiškai modifikuotu pagrindiniu histosuderinamumo kompleksu

Info

Publication number
LT3262932T
LT3262932T LTEP17184955.7T LT17184955T LT3262932T LT 3262932 T LT3262932 T LT 3262932T LT 17184955 T LT17184955 T LT 17184955T LT 3262932 T LT3262932 T LT 3262932T
Authority
LT
Lithuania
Prior art keywords
mouse
genetically modified
compatibility complex
modified historical
historical
Prior art date
Application number
LTEP17184955.7T
Other languages
English (en)
Inventor
Lynn Macdonald
Andrew J. Murphy
Cagan Gurer
John Mcwhirter
Vera VORONINA
Faith HARRIS
Sean Stevens
Original Assignee
Regeneron Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharmaceuticals, Inc. filed Critical Regeneron Pharmaceuticals, Inc.
Publication of LT3262932T publication Critical patent/LT3262932T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/072—Animals genetically altered by homologous recombination maintaining or altering function, i.e. knock in
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/15—Animals comprising multiple alterations of the genome, by transgenesis or homologous recombination, e.g. obtained by cross-breeding
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Environmental Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
LTEP17184955.7T 2011-10-28 2012-10-26 Pelės su genetiškai modifikuotu pagrindiniu histosuderinamumo kompleksu LT3262932T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161552587P 2011-10-28 2011-10-28
US201161552582P 2011-10-28 2011-10-28
US201261700908P 2012-09-14 2012-09-14

Publications (1)

Publication Number Publication Date
LT3262932T true LT3262932T (lt) 2019-08-26

Family

ID=47178940

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP17184955.7T LT3262932T (lt) 2011-10-28 2012-10-26 Pelės su genetiškai modifikuotu pagrindiniu histosuderinamumo kompleksu
LTEP12787255.4T LT2770821T (lt) 2011-10-28 2012-10-26 Genetiškai modifikuotą didįjį audinių dermės kompleksą turinčios pelės

Family Applications After (1)

Application Number Title Priority Date Filing Date
LTEP12787255.4T LT2770821T (lt) 2011-10-28 2012-10-26 Genetiškai modifikuotą didįjį audinių dermės kompleksą turinčios pelės

Country Status (27)

Country Link
US (3) US9615550B2 (lt)
EP (4) EP3563680B1 (lt)
JP (4) JP6154391B2 (lt)
KR (3) KR102295746B1 (lt)
CN (3) CN113564188B (lt)
AU (3) AU2012324016C1 (lt)
BR (1) BR112014009259A2 (lt)
CA (2) CA3074400C (lt)
CY (2) CY1119657T1 (lt)
DK (2) DK3262932T3 (lt)
ES (3) ES2651517T3 (lt)
HK (1) HK1249712B (lt)
HR (2) HRP20171761T1 (lt)
HU (2) HUE035652T2 (lt)
IL (3) IL232097A (lt)
LT (2) LT3262932T (lt)
MX (3) MX391222B (lt)
MY (2) MY164836A (lt)
NZ (1) NZ734532A (lt)
PL (2) PL2770821T3 (lt)
PT (2) PT2770821T (lt)
RS (2) RS56656B1 (lt)
SG (2) SG11201400933VA (lt)
SI (2) SI2770821T1 (lt)
SM (2) SMT201900478T1 (lt)
WO (1) WO2013063346A1 (lt)
ZA (1) ZA201403085B (lt)

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Publication number Publication date
JP2017143840A (ja) 2017-08-24
ES2651517T3 (es) 2018-01-26
EP3563680A1 (en) 2019-11-06
MX2014004895A (es) 2014-09-12
CN104039132B (zh) 2017-06-16
ES2962287T3 (es) 2024-03-18
PT2770821T (pt) 2017-12-18
MX376167B (es) 2025-03-07
KR20180128494A (ko) 2018-12-03
RS59082B1 (sr) 2019-09-30
SMT201900478T1 (it) 2019-09-09
IL261239B (en) 2019-11-28
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PL3262932T3 (pl) 2019-10-31
MY164836A (en) 2018-01-30
HUE035652T2 (en) 2018-05-28
MX391222B (es) 2025-03-21
AU2012324016C1 (en) 2018-02-15
CN107254480B (zh) 2021-08-10
LT2770821T (lt) 2017-12-11
KR102074145B1 (ko) 2020-02-07
US9615550B2 (en) 2017-04-11
AU2012324016B2 (en) 2016-01-28
EP3262932B1 (en) 2019-05-15
HK1249712B (en) 2020-06-26
HRP20171761T1 (hr) 2017-12-29
EP3262932A1 (en) 2018-01-03
NZ623456A (en) 2016-05-27
SMT201700576T1 (it) 2018-01-11
ZA201403085B (en) 2025-07-30
EP3563680B1 (en) 2023-08-30
EP3563680C0 (en) 2023-08-30
AU2012324016A1 (en) 2013-05-16
NZ719373A (en) 2018-06-29
CN104039132B9 (zh) 2017-09-05
RS56656B1 (sr) 2018-03-30
CA3074400A1 (en) 2013-05-02
WO2013063346A1 (en) 2013-05-02
DK3262932T3 (da) 2019-08-05
ES2741649T3 (es) 2020-02-11
KR101921126B1 (ko) 2018-11-23
US20200375160A1 (en) 2020-12-03
MY178723A (en) 2020-10-20
AU2017279797C1 (en) 2021-07-15
SI3262932T1 (sl) 2019-09-30
AU2016202688A1 (en) 2016-05-19
EP2770821A1 (en) 2014-09-03
CY1121869T1 (el) 2020-10-14
HK1200272A1 (en) 2015-08-07
JP2014532412A (ja) 2014-12-08
BR112014009259A2 (pt) 2020-10-27
HUE045879T2 (hu) 2020-01-28
US10869466B2 (en) 2020-12-22
AU2012324016A8 (en) 2016-03-03
JP6574457B2 (ja) 2019-09-11
KR20140089560A (ko) 2014-07-15
CN113564188B (zh) 2025-03-04
JP6154391B2 (ja) 2017-06-28
AU2016202688B2 (en) 2017-09-28
DK2770821T3 (da) 2017-11-27
IL232097A (en) 2017-06-29
IL261239A (en) 2018-10-31
HRP20191420T1 (hr) 2019-11-15
SI2770821T1 (en) 2018-01-31
AU2017279797A1 (en) 2018-01-25
CN107254480A (zh) 2017-10-17
SG10201603188SA (en) 2016-05-30
IL252022A0 (en) 2017-06-29
JP2019068857A (ja) 2019-05-09
SG11201400933VA (en) 2014-04-28
EP4311833A3 (en) 2024-05-01
CY1119657T1 (el) 2018-04-04
MX355725B (es) 2018-04-27
EP4311833A2 (en) 2024-01-31
EP2770821B1 (en) 2017-09-13
PL2770821T3 (pl) 2018-02-28
CN113564188A (zh) 2021-10-29
JP6866409B2 (ja) 2021-04-28
AU2017279797B2 (en) 2020-10-22
PT3262932T (pt) 2019-08-26
MX2020010763A (es) 2022-04-01
KR20200013810A (ko) 2020-02-07
US20130111617A1 (en) 2013-05-02
CA3074400C (en) 2025-03-25
NZ734532A (en) 2022-12-23
CN104039132A (zh) 2014-09-10
KR102295746B1 (ko) 2021-09-01
JP2020146041A (ja) 2020-09-17
CA2850387A1 (en) 2013-05-02
US20170164590A1 (en) 2017-06-15

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