SG11201601828XA - Humanized il-15 animals - Google Patents
Humanized il-15 animalsInfo
- Publication number
- SG11201601828XA SG11201601828XA SG11201601828XA SG11201601828XA SG11201601828XA SG 11201601828X A SG11201601828X A SG 11201601828XA SG 11201601828X A SG11201601828X A SG 11201601828XA SG 11201601828X A SG11201601828X A SG 11201601828XA SG 11201601828X A SG11201601828X A SG 11201601828XA
- Authority
- SG
- Singapore
- Prior art keywords
- humanized
- animals
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
- A01K67/027—New breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0278—Humanized animals, e.g. knockin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5443—IL-15
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2207/00—Modified animals
- A01K2207/15—Humanized animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/072—Animals genetically altered by homologous recombination maintaining or altering function, i.e. knock in
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/035—Animal model for multifactorial diseases
- A01K2267/0387—Animal model for diseases of the immune system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
- C12N2015/8527—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic for producing animal models, e.g. for tests or diseases
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361891013P | 2013-10-15 | 2013-10-15 | |
PCT/US2014/060568 WO2015057758A1 (en) | 2013-10-15 | 2014-10-15 | Humanized il-15 animals |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201601828XA true SG11201601828XA (en) | 2016-04-28 |
Family
ID=51830649
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201607768YA SG10201607768YA (en) | 2013-10-15 | 2014-10-15 | Humanized il-15 animals |
SG11201601828XA SG11201601828XA (en) | 2013-10-15 | 2014-10-15 | Humanized il-15 animals |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201607768YA SG10201607768YA (en) | 2013-10-15 | 2014-10-15 | Humanized il-15 animals |
Country Status (28)
Country | Link |
---|---|
US (5) | US9155290B2 (en) |
EP (3) | EP2908626B1 (en) |
JP (3) | JP6492095B2 (en) |
KR (1) | KR102376041B1 (en) |
CN (2) | CN109090037B (en) |
AU (2) | AU2014337526B2 (en) |
BR (1) | BR112016008175A2 (en) |
CA (1) | CA2926090C (en) |
CY (2) | CY1118675T1 (en) |
DK (2) | DK2908626T3 (en) |
ES (2) | ES2715949T3 (en) |
HK (1) | HK1210659A1 (en) |
HR (2) | HRP20170380T1 (en) |
HU (2) | HUE043969T2 (en) |
IL (2) | IL244525B (en) |
LT (2) | LT2908626T (en) |
MX (1) | MX2016004781A (en) |
NZ (1) | NZ718655A (en) |
PL (2) | PL3138397T3 (en) |
PT (2) | PT3138397T (en) |
RS (2) | RS55472B1 (en) |
RU (1) | RU2674910C2 (en) |
SG (2) | SG10201607768YA (en) |
SI (2) | SI3138397T1 (en) |
SM (1) | SMT201700024B (en) |
TR (1) | TR201904342T4 (en) |
WO (1) | WO2015057758A1 (en) |
ZA (1) | ZA201601676B (en) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP4049535A1 (en) | 2009-10-06 | 2022-08-31 | Regeneron Pharmaceuticals, Inc. | Genetically modified mice and engraftment |
RU2730643C2 (en) | 2011-02-15 | 2020-08-24 | Ридженерон Фармасьютикалз, Инк. | Humanised m-csf mice |
KR102594390B1 (en) | 2012-09-07 | 2023-10-27 | 예일 유니버시티 | Genetically modified non-human animals and methods of use thereof |
CN104918483B (en) | 2012-11-05 | 2018-05-11 | 再生元制药公司 | Generation and the method using genetically modified non-human animal |
EP2908626B1 (en) | 2013-10-15 | 2016-12-07 | Regeneron Pharmaceuticals, Inc. | Humanized il-15 animals |
EP3636073B1 (en) | 2014-05-05 | 2023-11-15 | Regeneron Pharmaceuticals, Inc. | Humanized c5 and c3 animals |
NO2785538T3 (en) | 2014-05-07 | 2018-08-04 | ||
CN113045639A (en) | 2014-05-19 | 2021-06-29 | 再生元制药公司 | Genetically modified non-human animals expressing human EPO |
CA2967834C (en) | 2014-12-05 | 2024-01-16 | Regeneron Pharmaceuticals, Inc. | Non-human animals having a humanized cluster of differentiation 47 gene |
FI3282835T3 (en) * | 2015-04-13 | 2023-07-20 | Regeneron Pharma | Humanized sirpa-il15 knockin mice and methods of use thereof |
KR102487839B1 (en) | 2016-02-04 | 2023-01-12 | 리제너론 파마슈티칼스 인코포레이티드 | Non-human animals with an engineered ANGPTL8 gene |
KR20230021759A (en) | 2016-02-29 | 2023-02-14 | 리제너론 파마슈티칼스 인코포레이티드 | Rodents having a humanized tmprss gene |
DK3476865T3 (en) | 2016-06-28 | 2023-12-18 | Biocytogen Pharmaceuticals Beijing Co Ltd | PROCEDURE FOR CONSTRUCTION OF PD-1 GENE-MODIFIED HUMANIZED ANIMAL MODEL AND USE THEREOF |
US11317611B2 (en) | 2016-08-31 | 2022-05-03 | Biocytogen Pharmaceuticals (Beijing) Co., Ltd. | Genetically modified non-human animal with human or chimeric PD-L1 |
CN107815467B (en) | 2016-08-31 | 2021-03-16 | 百奥赛图(北京)医药科技股份有限公司 | Preparation method and application of humanized gene modified animal model |
WO2018041120A1 (en) | 2016-08-31 | 2018-03-08 | Beijing Biocytogen Co., Ltd | Genetically modified non-human animal with human or chimeric tigit |
CN107815468B (en) | 2016-08-31 | 2021-03-16 | 百奥赛图(北京)医药科技股份有限公司 | Preparation method and application of humanized gene modified animal model |
CN108070613B (en) | 2016-11-11 | 2020-03-13 | 百奥赛图江苏基因生物技术有限公司 | Preparation method and application of humanized gene modified animal model |
WO2018086594A1 (en) | 2016-11-11 | 2018-05-17 | Beijing Biocytogen Co., Ltd | Genetically modified non-human animal with human or chimeric tim-3 |
CN108239659B (en) | 2016-12-23 | 2020-03-03 | 百奥赛图江苏基因生物技术有限公司 | Preparation method and application of humanized gene modified animal model |
CN108424928B (en) | 2016-12-30 | 2021-03-16 | 百奥赛图(北京)医药科技股份有限公司 | Preparation method and application of humanized gene modified animal model |
CN108467873B (en) | 2017-03-17 | 2020-03-13 | 百奥赛图江苏基因生物技术有限公司 | Preparation method and application of CD132 gene-deleted immunodeficiency animal model |
WO2018177441A1 (en) | 2017-03-31 | 2018-10-04 | Beijing Biocytogen Co., Ltd | GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC SIRPα |
CN108588126B (en) | 2017-03-31 | 2020-04-10 | 北京百奥赛图基因生物技术有限公司 | Preparation method and application of humanized modified animal model of CD47 gene |
CN109136261B (en) | 2017-06-19 | 2021-03-16 | 百奥赛图(北京)医药科技股份有限公司 | Preparation method and application of humanized CD28 gene modified animal model |
CN109136274B (en) | 2017-06-19 | 2021-04-23 | 百奥赛图江苏基因生物技术有限公司 | Preparation method and application of humanized CD40 gene modified animal model |
CN109136275B (en) | 2017-06-19 | 2021-03-16 | 百奥赛图(北京)医药科技股份有限公司 | Preparation method and application of humanized GITR gene modified animal model |
CN112118734A (en) * | 2017-08-09 | 2020-12-22 | 杰克逊实验室 | Immunodeficient mice expressing human interleukin 15 |
WO2019072241A1 (en) | 2017-10-13 | 2019-04-18 | Beijing Biocytogen Co., Ltd | Genetically modified non-human animal with human or chimeric pd-1 |
CN109913493B (en) | 2017-12-12 | 2021-03-16 | 百奥赛图江苏基因生物技术有限公司 | Preparation method and application of humanized CD3 gene modified animal model |
CN116200426A (en) | 2018-07-16 | 2023-06-02 | 瑞泽恩制药公司 | Non-human animal model of DITRA disease and uses thereof |
CN111057721B (en) | 2018-10-12 | 2021-03-16 | 百奥赛图(北京)医药科技股份有限公司 | Preparation method and application of humanized IL-4 and/or IL-4R alpha modified animal model |
CN111304247B (en) | 2018-12-20 | 2021-03-16 | 百奥赛图江苏基因生物技术有限公司 | Preparation method and application of humanized LAG-3 gene modified animal model |
WO2020135518A1 (en) * | 2018-12-25 | 2020-07-02 | Biocytogen Jiangsu Co., Ltd. | Genetically modified non-human animal with human or chimeric il15 |
CN114107385A (en) * | 2019-01-17 | 2022-03-01 | 百奥赛图(北京)医药科技股份有限公司 | Humanized transgenic animal |
SG11202108454RA (en) | 2019-04-04 | 2021-09-29 | Regeneron Pharma | Non-human animals comprising a humanized coagulation factor 12 locus |
WO2020247452A1 (en) | 2019-06-04 | 2020-12-10 | Regeneron Pharmaceuticals, Inc. | Non-human animals comprising a humanized ttr locus with a beta-slip mutation and methods of use |
BR112021022722A2 (en) | 2019-06-07 | 2022-01-04 | Regeneron Pharma | Non-human animal, non-human animal cell, non-human animal genome, humanized non-human animal albumin gene, targeting vector, method of evaluating the activity of a reagent, and, method of optimizing the activity of a reagent |
WO2021129766A1 (en) * | 2019-12-25 | 2021-07-01 | 江苏集萃药康生物科技股份有限公司 | Il-15 humanized mouse model and use thereof |
KR20220133248A (en) * | 2020-01-28 | 2022-10-04 | 리제너론 파마슈티칼스 인코포레이티드 | Non-Human Animals Comprising Humanized PNPLA3 Locus and Methods of Use |
CN111485001A (en) * | 2020-04-14 | 2020-08-04 | 澎立生物医药技术(上海)有限公司 | Construction method of humanized immune system mouse with NK (Natural killer) cell and ADCC (advanced Charge coupled device) capabilities |
CN112481303B (en) * | 2021-02-09 | 2021-05-25 | 百奥赛图(北京)医药科技股份有限公司 | IL15RA gene humanized non-human animal and construction method and application thereof |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001239750A1 (en) * | 2000-02-08 | 2001-08-20 | Genaissance Pharmaceuticals, Inc. | Haplotypes of the interleukin 15 gene |
US7759541B2 (en) * | 2004-12-13 | 2010-07-20 | Iti Life Sciences | Transgenic animals for assessing drug metabolism and toxicity |
NZ563263A (en) * | 2005-05-17 | 2010-04-30 | Univ Connecticut | Composition and methods for immunomodulation in an organism |
HUE057994T2 (en) * | 2008-06-27 | 2022-06-28 | Merus Nv | Antibody producing transgenic murine animal |
RU2425880C2 (en) * | 2009-07-30 | 2011-08-10 | Учреждение Российской академии наук Институт общей генетики им. Н.И. Вавилова РАН | Method of producing transgene mice |
EP4049535A1 (en) | 2009-10-06 | 2022-08-31 | Regeneron Pharmaceuticals, Inc. | Genetically modified mice and engraftment |
HUE038684T2 (en) * | 2009-12-21 | 2018-11-28 | Regeneron Pharma | Humanized fc gamma r mice |
RU2730643C2 (en) | 2011-02-15 | 2020-08-24 | Ридженерон Фармасьютикалз, Инк. | Humanised m-csf mice |
PT3590332T (en) * | 2011-10-28 | 2022-05-27 | Regeneron Pharma | Genetically modified mice expressing chimeric major histocompatibility complex (mhc) ii molecules |
US9043996B2 (en) * | 2011-10-28 | 2015-06-02 | Regeneron Pharmaceuticals, Inc. | Genetically modified major histocompatibility complex animals |
CN108866101A (en) | 2011-10-28 | 2018-11-23 | 瑞泽恩制药公司 | Humanization IL-6 and IL-6 receptor |
RS56656B1 (en) | 2011-10-28 | 2018-03-30 | Regeneron Pharma | Genetically modified major histocompatibility complex mice |
US8962913B2 (en) | 2012-06-18 | 2015-02-24 | Regeneron Pharmaceuticals, Inc. | Humanized IL-7 rodents |
KR102594390B1 (en) | 2012-09-07 | 2023-10-27 | 예일 유니버시티 | Genetically modified non-human animals and methods of use thereof |
CN104918483B (en) | 2012-11-05 | 2018-05-11 | 再生元制药公司 | Generation and the method using genetically modified non-human animal |
EP2958937B1 (en) | 2013-02-22 | 2018-08-15 | Regeneron Pharmaceuticals, Inc. | Mice expressing humanized major histocompatibility complex |
SG10201902547SA (en) | 2013-09-23 | 2019-04-29 | Regeneron Pharma | Non-human animals having a humanized signal-regulatory protein gene |
EP2908626B1 (en) | 2013-10-15 | 2016-12-07 | Regeneron Pharmaceuticals, Inc. | Humanized il-15 animals |
-
2014
- 2014-10-15 EP EP14790452.8A patent/EP2908626B1/en active Active
- 2014-10-15 RS RS20161140A patent/RS55472B1/en unknown
- 2014-10-15 EP EP18206034.3A patent/EP3461331A1/en not_active Withdrawn
- 2014-10-15 ES ES16192440T patent/ES2715949T3/en active Active
- 2014-10-15 CA CA2926090A patent/CA2926090C/en active Active
- 2014-10-15 WO PCT/US2014/060568 patent/WO2015057758A1/en active Application Filing
- 2014-10-15 CN CN201810808707.3A patent/CN109090037B/en active Active
- 2014-10-15 RS RS20190349A patent/RS58465B1/en unknown
- 2014-10-15 SI SI201431130T patent/SI3138397T1/en unknown
- 2014-10-15 US US14/514,454 patent/US9155290B2/en active Active
- 2014-10-15 NZ NZ718655A patent/NZ718655A/en unknown
- 2014-10-15 SG SG10201607768YA patent/SG10201607768YA/en unknown
- 2014-10-15 DK DK14790452.8T patent/DK2908626T3/en active
- 2014-10-15 JP JP2016549191A patent/JP6492095B2/en active Active
- 2014-10-15 AU AU2014337526A patent/AU2014337526B2/en active Active
- 2014-10-15 DK DK16192440.2T patent/DK3138397T3/en active
- 2014-10-15 TR TR2019/04342T patent/TR201904342T4/en unknown
- 2014-10-15 SI SI201430109T patent/SI2908626T1/en unknown
- 2014-10-15 ES ES14790452.8T patent/ES2613379T3/en active Active
- 2014-10-15 MX MX2016004781A patent/MX2016004781A/en unknown
- 2014-10-15 PL PL16192440T patent/PL3138397T3/en unknown
- 2014-10-15 PT PT16192440T patent/PT3138397T/en unknown
- 2014-10-15 KR KR1020167009228A patent/KR102376041B1/en active IP Right Grant
- 2014-10-15 HU HUE16192440A patent/HUE043969T2/en unknown
- 2014-10-15 EP EP16192440.2A patent/EP3138397B1/en active Active
- 2014-10-15 HU HUE14790452A patent/HUE033272T2/en unknown
- 2014-10-15 LT LTEP14790452.8T patent/LT2908626T/en unknown
- 2014-10-15 PL PL14790452T patent/PL2908626T3/en unknown
- 2014-10-15 CN CN201480056455.3A patent/CN105744829B/en active Active
- 2014-10-15 BR BR112016008175A patent/BR112016008175A2/en not_active Application Discontinuation
- 2014-10-15 RU RU2016116847A patent/RU2674910C2/en active
- 2014-10-15 LT LTEP16192440.2T patent/LT3138397T/en unknown
- 2014-10-15 SG SG11201601828XA patent/SG11201601828XA/en unknown
- 2014-10-15 PT PT147904528T patent/PT2908626T/en unknown
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2015
- 2015-09-01 US US14/842,342 patent/US20150366175A1/en not_active Abandoned
- 2015-11-20 HK HK15111500.3A patent/HK1210659A1/en unknown
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2016
- 2016-03-10 ZA ZA2016/01676A patent/ZA201601676B/en unknown
- 2016-03-10 IL IL24452516A patent/IL244525B/en active IP Right Grant
-
2017
- 2017-01-04 CY CY20171100008T patent/CY1118675T1/en unknown
- 2017-01-16 SM SM201700024T patent/SMT201700024B/en unknown
- 2017-03-07 HR HRP20170380TT patent/HRP20170380T1/en unknown
- 2017-12-06 US US15/832,976 patent/US10561125B2/en active Active
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2018
- 2018-10-16 JP JP2018194898A patent/JP6600061B2/en active Active
-
2019
- 2019-03-18 CY CY20191100323T patent/CY1121405T1/en unknown
- 2019-03-20 HR HRP20190542TT patent/HRP20190542T1/en unknown
- 2019-10-03 JP JP2019182817A patent/JP2019216750A/en active Pending
- 2019-10-10 IL IL269907A patent/IL269907B/en active IP Right Grant
-
2020
- 2020-01-02 US US16/732,400 patent/US11503813B2/en active Active
- 2020-12-08 AU AU2020286186A patent/AU2020286186A1/en active Pending
-
2022
- 2022-10-17 US US18/047,014 patent/US20230189772A1/en active Pending
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GB201318283D0 (en) | Antibodies |