KR970009800A - 경구 투여용 약제학적 조성물 - Google Patents

경구 투여용 약제학적 조성물 Download PDF

Info

Publication number
KR970009800A
KR970009800A KR1019960023834A KR19960023834A KR970009800A KR 970009800 A KR970009800 A KR 970009800A KR 1019960023834 A KR1019960023834 A KR 1019960023834A KR 19960023834 A KR19960023834 A KR 19960023834A KR 970009800 A KR970009800 A KR 970009800A
Authority
KR
South Korea
Prior art keywords
composition
weight
pharmaceutical composition
sugar
composition according
Prior art date
Application number
KR1019960023834A
Other languages
English (en)
Other versions
KR100451269B1 (ko
Inventor
예트카 빈프리트
하거 외르그-크리스티안
뒤르 만프레트
Original Assignee
헨리히 베.레쉬케, 라인홀트 뮐러
뢰네-포울렌크 로러 게엠베하
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 헨리히 베.레쉬케, 라인홀트 뮐러, 뢰네-포울렌크 로러 게엠베하 filed Critical 헨리히 베.레쉬케, 라인홀트 뮐러
Publication of KR970009800A publication Critical patent/KR970009800A/ko
Application granted granted Critical
Publication of KR100451269B1 publication Critical patent/KR100451269B1/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08—Oxides; Hydroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/12—Magnesium silicate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/42—Phosphorus; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

하나 이상의 제산성 활성 물질 및 추가의 성분을 포함하는 경구 투여용 약제학적 조성물이 기술되어 있다.
본 발명 조성물을 방부제가 거의 없도록 액체 내지 반고체 경도를 가진다. 추가의 성분으로서, 본 발명의 조성물은 즉시 사용가능한 조성물에 대해 45중량% 이상의 당 및/또는 당 알콜 및 40중량% 이하의 약제학적으로 무해한 용매를 포함한다.

Description

경구 투여용 약제학적 조성물
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (12)

  1. 하나 이상의 제산성 활성 물질과 추가의 성분을 포함하는 경구 투여용 약제학적 조성물에 있어서, 액체 내지 반고체의 경도를 가지고, 방부제가 거의 없으며, 즉시 사용가능한 조성물에 대해 추가의 성분으로서 45중량% 이상의 당 및/또는 당 알콜, 및 40중량% 이하의 약제학적으로 무해한 용매를 포함하는 특징으로 하는 경구 투여용 약제학적 조성물.
  2. 제1항에 있어서, 액체 내지 반고체 조성물의 고체 물질함량이 즉시 사용가능한 조성물에 대해 최대 88중량%인 약제학적 조성물.
  3. 제1항 또는 제2항에 있어서, 조성물이 약제학적으로 무해한 용매로서 물을 포함하는 약제학적 조성물.
  4. 제1항 내지 제3항 중 어느 한 항에 있어서, 조성물이 즉시 사용가능한 조성물에 대해 12중량% 내지 35중량%의 물을 포함하는 약제학적 조성물.
  5. 제1항 내지 제4항 중 어느 한 항에 있어서, 조성물이 즉시 사용가능한 조성물에 대해 5중량% 내지 43중량%, 바람직하게는 12중량% 내지 30중량%의 제산성 활성 성분을 포함하는 약제학적 조성물.
  6. 제1항 내지 제5항 중 어느 한 항에 있어서, 조성물이 제산성 활성 물질로서 수산화 알루미늄, 수산화 마그네슘, 삼규한 마그네슘, 탄산 마그네슘, 인산 마그네슘, 탄산 칼슘, 인산 칼슘, 나트륨 시트레이트, 산화 마그네슘, 마갈드레이트, 하이드로탈사이트, 탄산수소나트륨 및/또는 염기성 탄산 비스무트를 함유하는 약제학적 조성물.
  7. 제1항 내지 제6항 중 어느 한 항에 있어서, 조성물이 즉시 사용가능한 조성물에 대해 당 및/또는 당 알콜을 45중량% 내지 80중량%, 바람직하게는 48중량% 내지 70중량%의 농도로 함유하는 약제학적 조성물.
  8. 제1항 내지 제7항 중 어느 한 항에 있어서, 조성물이 당알콜로서 솔비톨 및/또는 말티톨을 포함하는 약제학적 조성물.
  9. 제1항 내지 제8항 중 어느 한 항에 있어서, 조성물이 당으로서 수크로즈를 포함하는 약제학적 조성물.
  10. 제1항 내지 제9항 중 어느 한 항에 있어서, 조성물이 젤라틴성 경도를 가지는 약제학적 조성물.
  11. 제1항 내지 제10항 중 어느 한 항에 있어서, 조성물이 성분으로서 2중량% 내지 8중량%의 글리세롤, 0.2중량% 내지 2중량%의 농후제, 특히 크산탄 검, 구아 검 및/ 또는 셀룰로오즈 유도체, 바람직하게는 미소결정질 셀룰로오즈, 메틸 셀룰로오즈, 하이드록시에틸 셀룰로오즈, 메틸하이드록시프로필 셀룰로오즈, 및 /또는 하이드록시프로필 셀룰로오즈 및 0.05중량% 내지 0.7중량%의 방향족 물질을 추가로 포함하는 약제학적 조성물.
  12. 제1항 내지 제11항 중 어느 한 항에 있어서, 조성물이 주요 성분으로서 12중량% 내지 28중량%의 제산성 활성 물질, 각 활성 물질의 혼합물, 46중량% 내지 58중량%의 당 및/또는 당 알콜, 18중량% 내지 30중량%의 물을 포함하는 약제학적 조성물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019960023834A 1995-08-14 1996-06-21 경구투여용약제학적제산제조성물 KR100451269B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19529862A DE19529862A1 (de) 1995-08-14 1995-08-14 Pharmazeutische, oral anwendbare Zubereitung
DE19529862.4 1995-08-14

Publications (2)

Publication Number Publication Date
KR970009800A true KR970009800A (ko) 1997-03-27
KR100451269B1 KR100451269B1 (ko) 2005-08-17

Family

ID=7769445

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019960023834A KR100451269B1 (ko) 1995-08-14 1996-06-21 경구투여용약제학적제산제조성물

Country Status (9)

Country Link
US (2) US5858413A (ko)
EP (1) EP0761207A3 (ko)
JP (1) JPH0952835A (ko)
KR (1) KR100451269B1 (ko)
AU (1) AU698992B2 (ko)
CA (1) CA2179682C (ko)
DE (1) DE19529862A1 (ko)
TW (1) TW501930B (ko)
ZA (1) ZA965222B (ko)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7051086B2 (en) 1995-07-27 2006-05-23 Digimarc Corporation Method of linking on-line data to printed documents
US5914135A (en) * 1997-04-16 1999-06-22 Mcneil-Ppc, Inc. Liquid antacid compositions
AU2004201831B2 (en) * 1998-09-21 2006-11-02 Mcneil-Ppc, Inc. Heat stable antacid and antigas suspensions
US7163705B2 (en) * 1998-12-15 2007-01-16 Wm. Wrigley Jr. Company Coated chewing gum product and method of making
US6586023B1 (en) 1998-12-15 2003-07-01 Wm. Wrigley Jr. Company Process for controlling release of active agents from a chewing gum coating and product thereof
US6627234B1 (en) 1998-12-15 2003-09-30 Wm. Wrigley Jr. Company Method of producing active agent coated chewing gum products
US6531114B1 (en) 1999-04-06 2003-03-11 Wm. Wrigley Jr. Company Sildenafil citrate chewing gum formulations and methods of using the same
US6800578B2 (en) 1999-01-29 2004-10-05 Akzo Nobel Nv Process for producing anionic clay using boehmite which has been peptized with an acid
US6426090B1 (en) * 1999-04-06 2002-07-30 Wm. Wrigley Jr. Company Over-coated product including tableted center and medicament
US6355265B1 (en) 1999-04-06 2002-03-12 Wm. Wrigley Jr. Company Over-coated chewing gum formulations
US7935362B2 (en) * 1999-04-06 2011-05-03 Wm. Wrigley Jr. Company Over-coated product including consumable center and medicament
US6322806B1 (en) 1999-04-06 2001-11-27 Wm. Wrigley Jr. Company Over-coated chewing gum formulations including tableted center
US20020159956A1 (en) * 1999-04-06 2002-10-31 Ream Ronald L. Over-coated chewing gum formulations
US6773716B2 (en) 1999-04-06 2004-08-10 Wm. Wrigley Jr. Company Over-coated chewing gum formulations
RU2219912C2 (ru) * 1999-04-06 2003-12-27 Вм. Ригли Дж. Компани Композиции жевательной резинки с внешним покрытием
US6245913B1 (en) 1999-06-30 2001-06-12 Wockhardt Europe Limited Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
US6569472B1 (en) 2000-09-01 2003-05-27 Wm. Wrigley Jr. Company Coated chewing gum products containing antacid and method of making
US6541048B2 (en) 1999-09-02 2003-04-01 Wm. Wrigley Jr. Company Coated chewing gum products containing an acid blocker and process of preparing
US6663849B1 (en) 2000-09-01 2003-12-16 Wm. Wrigley Jr. Company Antacid chewing gum products coated with high viscosity materials
US6645535B2 (en) 1999-09-02 2003-11-11 Wm. Wrigley Jr. Company Method of making coated chewing gum products containing various antacids
US9387168B2 (en) 1999-09-20 2016-07-12 Jack Barreca Chewing gum with tomatidine
US9253991B2 (en) 1999-09-20 2016-02-09 Jack Barreca Chewing gum with B vitamins
US6491540B1 (en) * 1999-09-20 2002-12-10 Jack Barreca Center-filled supplement gum
US6350480B1 (en) 1999-12-30 2002-02-26 Wm. Wrigley Jr. Company Chewing gum product including a hydrophilic gum base and method of producing
US6572900B1 (en) 2000-06-09 2003-06-03 Wm. Wrigley, Jr. Company Method for making coated chewing gum products including a high-intensity sweetener
US7115288B2 (en) * 2000-06-09 2006-10-03 Wm. Wrigley Jr. Company Method for making coated chewing gum products with a coating including an aldehyde flavor and a dipeptide sweetener
US6444241B1 (en) 2000-08-30 2002-09-03 Wm. Wrigley Jr. Company Caffeine coated chewing gum product and process of making
US6579545B2 (en) 2000-12-22 2003-06-17 Wm. Wrigley Jr. Company Coated chewing gum products containing an antigas agent
SG104293A1 (en) * 2002-01-09 2004-06-21 Micron Technology Inc Elimination of rdl using tape base flip chip on flex for die stacking
US20030232092A1 (en) * 2002-06-14 2003-12-18 Hasenmayer Donald L. Liquid antacid compositions
US20040219229A1 (en) * 2003-04-30 2004-11-04 Tim Clarot Migraine relief composition and methods of using and forming same
US7198653B2 (en) 2003-07-31 2007-04-03 Delavau Llc Calcium carbonate granulation
US20050100637A1 (en) 2003-11-12 2005-05-12 Robert Murray Carbohydrate and electrolyte replacement composition
ES2278511B1 (es) * 2005-07-28 2008-06-16 Laboratorios Almirall S.A. Comprimidos con perfil de disolucion mejorado.
US9138414B1 (en) 2006-09-15 2015-09-22 Delavau Llc Calcium supplement having enhanced absorption
US20100094075A1 (en) * 2008-10-10 2010-04-15 Hologic Inc. Expandable medical devices with reinforced elastomeric members and methods employing the same
US8435590B2 (en) * 2008-11-24 2013-05-07 Stokely-Van Camp, Inc. Use of novel carbohydrates and carbohydrate blends to provide a sports beverage with increased absorption
US8992893B2 (en) 2011-04-19 2015-03-31 Arms Pharmaceutical, Llc Method of inhibiting harmful microorganisms and barrier-forming composition therefor
US10426761B2 (en) 2011-04-19 2019-10-01 Arms Pharmaceutical, Llc Method for treatment of disease caused or aggravated by microorganisms or relieving symptoms thereof
WO2013058996A1 (en) 2011-10-19 2013-04-25 R.P. Scherer Technologies, Llc Two phase pharmaceutical delivery system
WO2014107572A1 (en) * 2013-01-04 2014-07-10 ARMS Pharmaceutical LLC Body surface treatment composition and method
EP3302566A1 (en) 2015-05-29 2018-04-11 Johnson & Johnson Consumer Inc. Use of organic citrus extract with high antimicrobial capacity as a preservative system in liquids, emulsions, suspensions, creams and antacids
RU2715906C2 (ru) 2015-05-29 2020-03-04 Джонсон энд Джонсон Консьюмер Инк. Применение органического экстракта цитрусовых с высокой противомикробной активностью и ксилита в качестве системы консервантов в жидкостях, эмульсиях, суспензиях, кремах и антацидах

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3041239A (en) * 1959-05-28 1962-06-26 Johnson & Johnson Stable aqueous salicylamide composition and method of preparing same
DE1617527A1 (de) * 1966-09-06 1971-04-08 Hoffmann La Roche Arzneimittelzubereitung und deren Herstellung
GB1435892A (en) * 1972-07-04 1976-05-19 Beecham Group Ltd Aluminium complexes of guaiphenesin
US4145440A (en) * 1977-08-18 1979-03-20 The Upjohn Company Liquid suspension of an aluminum salt of ibuprofen
EP0094116A3 (en) * 1982-05-06 1984-08-01 The Procter & Gamble Company Therapeutic granules
CA1239349A (en) * 1983-10-10 1988-07-19 Eberhard F. Gottwald Pharmaceutical composition containing cimetidine
US5173305A (en) * 1985-03-06 1992-12-22 Grimberg Georges Serge Composition for protection of oesogastroduodenal mucous membrane
GB8623557D0 (en) * 1986-10-01 1986-11-05 Boots Co Plc Therapeutic agents
GB8710965D0 (en) * 1987-05-08 1987-06-10 Smith Kline French Lab Pharmaceutical compositions
KR100238565B1 (ko) * 1991-04-04 2000-02-01 데이비드 엠 모이어 상부 위장관 통증을 치료하기 위한 섭취가능한 약학적 조성물
US5272137A (en) * 1992-02-14 1993-12-21 Mcneil-Pfc, Inc. Aqueous pharmaceutical suspension for pharmaceutical actives
US5330760A (en) * 1992-08-27 1994-07-19 Sterling Winthrop Inc. Effervescent antacid
WO2005040948A1 (ja) * 2003-10-23 2005-05-06 Fujitsu Limited 加工情報作成装置、プログラム及び加工情報作成方法
JP6817860B2 (ja) * 2017-03-21 2021-01-20 株式会社Ｓｃｒｅｅｎホールディングス 基板処理装置および基板処理方法

Also Published As

Publication number Publication date
US5858413A (en) 1999-01-12
EP0761207A3 (de) 1998-03-25
AU5609296A (en) 1997-02-20
EP0761207A2 (de) 1997-03-12
DE19529862A1 (de) 1997-02-20
CA2179682C (en) 2004-01-27
JPH0952835A (ja) 1997-02-25
KR100451269B1 (ko) 2005-08-17
TW501930B (en) 2002-09-11
US6103274A (en) 2000-08-15
CA2179682A1 (en) 1997-02-15
ZA965222B (en) 1997-01-08
MX9602270A (es) 1997-10-31
AU698992B2 (en) 1998-11-19

Similar Documents

Publication Publication Date Title
KR970009800A (ko) 경구 투여용 약제학적 조성물
KR950007841A (ko) 트라마돌 염을 함유하는 서방성 약물 제제
KR970703132A (ko) 듀오카르마이신 유도체의 안정화 방법(method for stabilizing duocarmycin derivatives)
KR950701224A (ko) 경구 현탁액 제형을 위한 안정한 수화 세팔로스포린 건조 분말(Stable hydrated cephalosporin dry powder for aral suspension formulation)
US20030008851A1 (en) Acne treatment including dual-package system
BG106439A (en) Pharmaceutical composition of improved solubility and oral absorptivity, containing benzamide derivative
KR920021139A (ko) 약학 조성물
DE69927963D1 (de) Gelierbare pharmazeutische zusammensetzungen
KR900700093A (ko) 수용성 이부프로펜 제제 및 그 제조방법
KR880004807A (ko) 수산화알루미늄을 함유하는 이부프로펜 조성물
YU54499A (sh) Farmaceutski preparat za primenu na mukozu
KR970706021A (ko) N-치환-o-톨루이딘유도체로 이루어진 약용배합제 및 경피흡수형제제(MEDICINAL ADJUVANTS CONSISTIONG OF AN N-SUBSTITUED-o-TOLUIDING DERIVANTIVE, AND PERCUTANEOUSLY ABSORBALE PREPARATIONS COMPRISING THE ADJUVANTS)
KR850004389A (ko) 경피침투가 증진된 생리학적 활성제제의 제조방법
KR940003547A (ko) 제산제
KR960000247A (ko) 사이클로스포린a 함유 조성물 및 그의 제조방법
KR100278343B1 (ko) 인공 타액
PT99446B (pt) Processo para a preparacao de composicoes anti-placa aperfeicoadas, constituidas por uma combinacao de um alcool de morfoninoamino com sais metalicos
MXPA97002456A (en) Liquid antiacidal compositions containing calcium carbonate and possibly simeticone as active compounds and monobasic potassium phosphate and potassium bicarbonate as regula
BG64664B1 (bg) Нимезулидни гел системи за локално приложение
RU2006101686A (ru) Композиции для местного применения, восстанавливающие структуру ногтей
KR920000326A (ko) 사람에 있어서 몰핀 및 동족체의 진통 효과에 대한 내성 발생을 방지하기 위한 gm₁모노시알로강글리오사이드 및 이의 내부 에스테르 유도체의 용도
KR930001903A (ko) 유비데카레논 경구용 수용액 제제
HUP0000125A2 (hu) Folyékony alendronátkészítmények, valamint eljárás azok előállítására
JP2002226315A (ja) 義歯用口腔湿潤剤
US4594359A (en) Pharmaceutical compositions

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 20130906

Year of fee payment: 10

FPAY Annual fee payment

Payment date: 20140901

Year of fee payment: 11

FPAY Annual fee payment

Payment date: 20150819

Year of fee payment: 12

EXPY Expiration of term