KR970005180B1 - Ldl-결합 과산화물에 의해 유발된 맥관성 병변증 예방을 위한 마그네슘-피리독살-5'-포스페이트-글루타민산염을 함유한 약학 조성물 - Google Patents
Ldl-결합 과산화물에 의해 유발된 맥관성 병변증 예방을 위한 마그네슘-피리독살-5'-포스페이트-글루타민산염을 함유한 약학 조성물 Download PDFInfo
- Publication number
- KR970005180B1 KR970005180B1 KR1019910008233A KR910008233A KR970005180B1 KR 970005180 B1 KR970005180 B1 KR 970005180B1 KR 1019910008233 A KR1019910008233 A KR 1019910008233A KR 910008233 A KR910008233 A KR 910008233A KR 970005180 B1 KR970005180 B1 KR 970005180B1
- Authority
- KR
- South Korea
- Prior art keywords
- ldl
- phosphate
- pharmaceutical composition
- peroxides
- pyridoxal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/32—Manganese; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4016963A DE4016963A1 (de) | 1990-05-25 | 1990-05-25 | Verwendung von magnesium-pyridoxal-5'-phosphat-glutaminat zur verhinderung von erkrankungen, die sich infolge von gefaessschaeden ergeben |
| DEP4016963.4 | 1990-05-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR910019616A KR910019616A (ko) | 1991-12-19 |
| KR970005180B1 true KR970005180B1 (ko) | 1997-04-14 |
Family
ID=6407228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019910008233A Expired - Fee Related KR970005180B1 (ko) | 1990-05-25 | 1991-05-22 | Ldl-결합 과산화물에 의해 유발된 맥관성 병변증 예방을 위한 마그네슘-피리독살-5'-포스페이트-글루타민산염을 함유한 약학 조성물 |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US5372999A (enExample) |
| EP (1) | EP0458287B1 (enExample) |
| JP (1) | JPH07119174B2 (enExample) |
| KR (1) | KR970005180B1 (enExample) |
| CN (1) | CN1050750C (enExample) |
| AT (1) | ATE142884T1 (enExample) |
| AU (1) | AU651108B2 (enExample) |
| CA (1) | CA2043228C (enExample) |
| CZ (1) | CZ280683B6 (enExample) |
| DE (2) | DE4016963A1 (enExample) |
| DK (1) | DK0458287T3 (enExample) |
| EG (1) | EG19730A (enExample) |
| ES (1) | ES2091262T3 (enExample) |
| GR (1) | GR3021077T3 (enExample) |
| HR (1) | HRP931445B1 (enExample) |
| HU (1) | HU219223B (enExample) |
| IE (1) | IE76728B1 (enExample) |
| IL (1) | IL98156A (enExample) |
| IN (1) | IN173057B (enExample) |
| LT (1) | LT3335B (enExample) |
| LV (1) | LV10046B (enExample) |
| MD (1) | MD306C2 (enExample) |
| MX (1) | MX171883B (enExample) |
| RU (1) | RU2041713C1 (enExample) |
| SI (1) | SI9110925A (enExample) |
| SK (1) | SK278896B6 (enExample) |
| UA (1) | UA26973A1 (enExample) |
| ZA (1) | ZA913692B (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19527820A1 (de) * | 1995-07-28 | 1997-01-30 | Leniger Follert Elfriede Prof | Arzneimittel zur Behandlung von Ulcera, insbesondere bei arteriellen und venösen Durchblutungsstörungen der Extremitäten, bei chronisch venöser Insuffizienz und Lymphödem |
| DE19532625C2 (de) * | 1995-09-04 | 2000-04-20 | Steigerwald Arzneimittelwerk | Verfahren zur Herstellung von Magnesium-pyridoxal-5'-phosphat-glutamat und dabei erhaltene Zwischenprodukte |
| US6043259A (en) * | 1998-07-09 | 2000-03-28 | Medicure Inc. | Treatment of cardiovascular and related pathologies |
| EP1169322B8 (en) | 1999-03-08 | 2006-09-13 | Medicure Inc. | Pyridoxal analogues for the treatment of disorders caused by a deficiency in vitamin b6 |
| AU5840200A (en) | 1999-07-13 | 2001-01-30 | Medicure Inc. | Treatment of diabetes and related pathologies |
| AU783855B2 (en) | 1999-08-24 | 2005-12-15 | Medicure International Inc. | Compositions for the treatment of cardiovascular diseases containing pyridoxal compounds and cardiovascular compounds |
| WO2001064692A1 (en) | 2000-02-29 | 2001-09-07 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
| US7442689B2 (en) * | 2000-02-29 | 2008-10-28 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
| JP2003528146A (ja) | 2000-03-28 | 2003-09-24 | メディキュア インターナショナル インコーポレイテッド | 脳血管疾患の治療 |
| RU2163132C1 (ru) * | 2000-06-01 | 2001-02-20 | Научно-исследовательский центр традиционной фитотерапии | Способ лечения сердечно-сосудистых заболеваний фитопрепаратом и лекарственный сбор для лечения сердечно-сосудистых заболеваний |
| US6897228B2 (en) * | 2000-07-07 | 2005-05-24 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: new uses |
| US6548519B1 (en) | 2001-07-06 | 2003-04-15 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: novel uses |
| DE60128912T9 (de) | 2000-07-07 | 2008-06-26 | Medicure International Inc. | Pyridoxin- und pyridoxalanaloga als cardiovasculäre therapeutika |
| US20070060549A1 (en) * | 2004-08-10 | 2007-03-15 | Friesen Albert D | Combination therapies employing ace inhibitors and uses thereof for the treatment of diabetic disorders |
| JP2008517956A (ja) | 2004-10-28 | 2008-05-29 | メディキュア・インターナショナル・インコーポレーテッド | 二重の抗血小板性/抗凝固性ピリドキシン類似体 |
| US7459468B2 (en) | 2004-10-28 | 2008-12-02 | Medicure International, Inc. | Aryl sulfonic pyridoxines as antiplatelet agents |
| CA2680801A1 (en) | 2007-03-14 | 2008-09-18 | Sierra Molecular Corporation | Compositions, systems, and methods for preservation and/or stabilizationof a cell and/or macromolecule |
| RU2484843C1 (ru) * | 2012-04-03 | 2013-06-20 | Алексей Кириллович Пехтерев | Лекарственный сбор растений для лечения сердечно-сосудистых заболеваний |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE246172C (enExample) | ||||
| DE2461742C2 (de) * | 1974-12-28 | 1983-01-27 | Steigerwald Arzneimittelwerk Gmbh, 6100 Darmstadt | Pyridoxin-5'-phosphorsäureester-Derivate sowie deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| DE3807895A1 (de) * | 1988-03-10 | 1989-09-21 | Knoll Ag | Erzeugnisse, enthaltend einen calciumantagonisten und einen lipidsenker |
-
1990
- 1990-05-25 DE DE4016963A patent/DE4016963A1/de active Granted
-
1991
- 1991-05-13 IN IN362CA1991 patent/IN173057B/en unknown
- 1991-05-15 ZA ZA913692A patent/ZA913692B/xx unknown
- 1991-05-16 IL IL9815691A patent/IL98156A/en active IP Right Grant
- 1991-05-22 EG EG32091A patent/EG19730A/xx active
- 1991-05-22 AT AT91108217T patent/ATE142884T1/de not_active IP Right Cessation
- 1991-05-22 ES ES91108217T patent/ES2091262T3/es not_active Expired - Lifetime
- 1991-05-22 EP EP91108217A patent/EP0458287B1/en not_active Expired - Lifetime
- 1991-05-22 DK DK91108217.0T patent/DK0458287T3/da active
- 1991-05-22 DE DE69122170T patent/DE69122170T2/de not_active Expired - Fee Related
- 1991-05-22 KR KR1019910008233A patent/KR970005180B1/ko not_active Expired - Fee Related
- 1991-05-23 SI SI9110925A patent/SI9110925A/sl unknown
- 1991-05-24 SK SK1563-91A patent/SK278896B6/sk unknown
- 1991-05-24 MX MX025919A patent/MX171883B/es unknown
- 1991-05-24 UA UA4895539A patent/UA26973A1/uk unknown
- 1991-05-24 RU SU914895539A patent/RU2041713C1/ru active
- 1991-05-24 HU HU756/91A patent/HU219223B/hu not_active IP Right Cessation
- 1991-05-24 CA CA002043228A patent/CA2043228C/en not_active Expired - Fee Related
- 1991-05-24 CZ CS911563A patent/CZ280683B6/cs not_active IP Right Cessation
- 1991-05-24 JP JP3149739A patent/JPH07119174B2/ja not_active Expired - Lifetime
- 1991-05-24 AU AU77301/91A patent/AU651108B2/en not_active Ceased
- 1991-05-24 IE IE178391A patent/IE76728B1/en not_active IP Right Cessation
- 1991-05-25 CN CN91104365A patent/CN1050750C/zh not_active Expired - Fee Related
-
1993
- 1993-04-02 US US08/041,896 patent/US5372999A/en not_active Expired - Fee Related
- 1993-05-14 LV LVP-93-343A patent/LV10046B/en unknown
- 1993-05-31 LT LTIP580A patent/LT3335B/lt not_active IP Right Cessation
- 1993-11-26 HR HRP-925/91A patent/HRP931445B1/xx not_active IP Right Cessation
-
1994
- 1994-11-25 MD MD94-0391A patent/MD306C2/ro active IP Right Grant
-
1996
- 1996-09-19 GR GR960402156T patent/GR3021077T3/el unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
St.27 status event code: A-0-1-A10-A12-nap-PA0109 |
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| R17-X000 | Change to representative recorded |
St.27 status event code: A-3-3-R10-R17-oth-X000 |
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| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
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| A201 | Request for examination | ||
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
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| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
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| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
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| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
St.27 status event code: A-1-2-D10-D21-exm-PE0902 |
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| T11-X000 | Administrative time limit extension requested |
St.27 status event code: U-3-3-T10-T11-oth-X000 |
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| T11-X000 | Administrative time limit extension requested |
St.27 status event code: U-3-3-T10-T11-oth-X000 |
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| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
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| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
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| G160 | Decision to publish patent application | ||
| PG1605 | Publication of application before grant of patent |
St.27 status event code: A-2-2-Q10-Q13-nap-PG1605 |
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| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
St.27 status event code: A-1-2-D10-D22-exm-PE0701 |
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| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
St.27 status event code: A-2-4-F10-F11-exm-PR0701 |
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| PR1002 | Payment of registration fee |
St.27 status event code: A-2-2-U10-U11-oth-PR1002 Fee payment year number: 1 |
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| LAPS | Lapse due to unpaid annual fee | ||
| PC1903 | Unpaid annual fee |
St.27 status event code: A-4-4-U10-U13-oth-PC1903 Not in force date: 20000806 Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE |
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St.27 status event code: N-4-6-H10-H13-oth-PC1903 Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE Not in force date: 20000806 |