KR960703625A - 제품의 살균방법(method for sterilizing products) - Google Patents

제품의 살균방법(method for sterilizing products) Download PDF

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Publication number
KR960703625A
KR960703625A KR1019960700298A KR19960700298A KR960703625A KR 960703625 A KR960703625 A KR 960703625A KR 1019960700298 A KR1019960700298 A KR 1019960700298A KR 19960700298 A KR19960700298 A KR 19960700298A KR 960703625 A KR960703625 A KR 960703625A
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South Korea
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product
blood
treated according
kgy
ethanol
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KR1019960700298A
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English (en)
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KR100389846B1 (ko
Inventor
에스. 켄트 랜들
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이.에이. 호톤
스터웨이즈 파이어니어 인코포레이티드
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029Radiation
    • A61L2/0035Gamma radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029Radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029Radiation
    • A61L2/0076Radiation using a photocatalyst or photosensitiser
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20Targets to be treated
    • A61L2202/22Blood or products thereof

Abstract

비루스, 박테리아, 이스트, 곰팡이, 미코플라즈마 및 기생충과 같은 생물학적 오염체를 제거하는 제품의 살균방법이 개시된다. 본 방법은 고체 20% 이하를 함유하는 형태로 제품을 제공하고 이어서 제품을 확장된 시간에 걸쳐 감마선 조사로서 조사하는 것을 포함한다. 일반적으로 제품을 10시간 보다 적지 않은 기간 동안 조사한다. 제품에서 낮은 수준의 고체에 관련하여 연장된 조사 시간은 실제로 제품에 대한 손상을 감소시킨다. 본 방법은 혈액 및 혈액 성분과 같은 과민 물질을 살균하는데 유용하다.

Description

제품의 살균방법(METHOD FOR STERILIZING PRODUCTS)
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (20)

  1. a) 20%중량 이하의 고형분을 가진 형태로 살균될 제품을 제공한다음: b) 약 20~32kGy의 총 조사량을 제공하는데 충분한 비율에서 10시간 보다 적지 않은 기간 동안 제품을 감마선 조사로서 조사하는 것으로 이루어진 제품의 살균방법.
  2. 제1항에 있어서, 주위 온도에서 방법을 수행하는 살균방법.
  3. 제1항에 있어서, 조사를 약 0.5kGy/hr~3.0kGy/hr의 비율에서 제공하는 살균방법.
  4. 제1항에 있어서, 제품을 약 20~40시간의 기간 동안 조사하는 살균방법.
  5. 제1항에 있어서, 제품을 약 20~30시간의 기간 동안 조사하는 살균방법.
  6. 제1항에 있어서, 제품이 유기 제품인 살균방법.
  7. 제1항에 있어서, 제품이 생물학적 제품인 살균방법.
  8. 제1항에 있어서, 제품이 혈액 또는 그의 성분인 살균방법.
  9. 제8항에 있어서, 혈액 또는 혈액 성분을 처음에 에탄올로서 처리하는 살균방법.
  10. 제9항에 있어서, 에탄올이 최종 농도 0.01%로 존재하며 혈액 또는 혈액 제품을 조사 전에 생리적으로 허용되는 희석제에서 희석하여 적어도 1:10의 최종 희석액을 얻는 살균방법.
  11. 제10항에 있어서, 생리적으로 허용되는 희석제가 pH 약 6.4~6.7인 개질된 시트레이트 포스페이트 덱스트로스 용액인 살균방법.
  12. 제1항에 있어서, 단계(a)에서 제품을 시트레이트 포스페이트 덱스트로스 용액으로서 희석하는 살균방법.
  13. 제12항에 있어서, 시트레이트 포스페이트 덱스트로스 용액이 약 0.01% v/v 에탄올을 함유하는 살균방법.
  14. 제1항에 있어서, 제품이 덱스트로스를 함유하는 살균방법.
  15. 제1항에 있어서, 제품이 단백질인 살균방법.
  16. 제15항에 있어서, 제품이 항체인 살균방법.
  17. 제1항의 방법에 따라 처리된 유기 제품.
  18. 제1항의 방법에 따라 처리된 생물학적 제품.
  19. 제1항의 방법에 따라 처리된 혈액 제품 또는 그의 성분.
  20. 제1항의 방법에 따라 처리된 덱스트로스 함유 제품.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019960700298A 1993-07-22 1994-07-22 조사과민제품의살균방법 KR100389846B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US095,698 1993-07-22
US095698 1993-07-22
US08/095,698 US5362442A (en) 1993-07-22 1993-07-22 Method for sterilizing products with gamma radiation

Publications (2)

Publication Number Publication Date
KR960703625A true KR960703625A (ko) 1996-08-31
KR100389846B1 KR100389846B1 (ko) 2003-10-30

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US (6) US5362442A (ko)
EP (1) EP0710124B1 (ko)
JP (1) JPH09500553A (ko)
KR (1) KR100389846B1 (ko)
AT (1) ATE235262T1 (ko)
AU (1) AU687425B2 (ko)
BR (1) BR9407138A (ko)
CA (1) CA2167528C (ko)
DE (1) DE69432351T2 (ko)
DK (1) DK0710124T3 (ko)
ES (1) ES2197907T3 (ko)
FI (1) FI960281A (ko)
NZ (1) NZ269786A (ko)
PT (1) PT710124E (ko)
WO (1) WO1995003071A1 (ko)

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