BR0311824A - Esterilização, estabilização e preservação de biológicos funcionais - Google Patents

Esterilização, estabilização e preservação de biológicos funcionais

Info

Publication number
BR0311824A
BR0311824A BR0311824-0A BR0311824A BR0311824A BR 0311824 A BR0311824 A BR 0311824A BR 0311824 A BR0311824 A BR 0311824A BR 0311824 A BR0311824 A BR 0311824A
Authority
BR
Brazil
Prior art keywords
preservation
sterilization
biologicals
functional
sterilized
Prior art date
Application number
BR0311824-0A
Other languages
English (en)
Inventor
Ernest K Manders
Christian D Manders
Original Assignee
Promethean Lifesciemces
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Promethean Lifesciemces filed Critical Promethean Lifesciemces
Publication of BR0311824A publication Critical patent/BR0311824A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0278Physical preservation processes
    • A01N1/0294Electromagnetic, i.e. using electromagnetic radiation or electromagnetic fields
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Electromagnetism (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

"ESTERILIZAçãO, ESTABILIZAçãO E PRESERVAçãO DE BIOLóGICOS FUNCIONAIS". Métodos são descritos para a esterilização de materiais biológicos em funcionamento, entidades bioquímicas e moléculas biologicamente ativas e para sua preservação para armazenamento em temperatura ambiente. Contaminantes biológicos são significativamente reduzidos no título ou eliminados enquanto mantendo a preservação da integridade funcional dos produtos esterilizados e estabilizados derivados dos presentes métodos. Esses materiais podem ser principalmente estruturais na função, tal como osso, ou podem demonstrar função molecular ativa, como no caso da hemoglobina e anticorpos. Tratamentos para estabilizar os biológicos esterilizados incluem a alteração da temperatura do material, controle da taxa da dose de radiação, otimização do tempo de irradiação, controle do conteúdo de oxigênio, o uso de estabilizadores, especificação de pH, inclusão de solventes particulares e alteração do tipo da radiação aplicada. Um produto biológico esterilizado e estabilizado tratado desse modo pode ser armazenado em temperatura ambiente, dessa maneira tornando-o muito mais disponível e mais fácil para usar contra biológicos liofilizados, congelados convencionais ou armazenados a frio.
BR0311824-0A 2002-06-07 2003-06-06 Esterilização, estabilização e preservação de biológicos funcionais BR0311824A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38717702P 2002-06-07 2002-06-07
PCT/US2003/017669 WO2003103390A1 (en) 2002-06-07 2003-06-06 Sterilization, stabilization and preservation of functional biologics

Publications (1)

Publication Number Publication Date
BR0311824A true BR0311824A (pt) 2005-03-15

Family

ID=29736277

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0311824-0A BR0311824A (pt) 2002-06-07 2003-06-06 Esterilização, estabilização e preservação de biológicos funcionais

Country Status (11)

Country Link
US (1) US20040126880A1 (pt)
EP (1) EP1511377A1 (pt)
JP (1) JP2005533041A (pt)
KR (1) KR20070118200A (pt)
CN (1) CN1665388A (pt)
AU (1) AU2003237391B2 (pt)
BR (1) BR0311824A (pt)
CA (1) CA2487826A1 (pt)
MX (1) MXPA04012771A (pt)
WO (1) WO2003103390A1 (pt)
ZA (1) ZA200409859B (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100316727A1 (en) * 2003-07-31 2010-12-16 Latino Joseph S Treatment of inflammatory disorders with ozone
US20050189302A1 (en) * 2003-07-31 2005-09-01 Latino Joseph S. Viral inactivation using ozone
US20100318014A1 (en) * 2003-07-31 2010-12-16 Latino Joseph S Treatment of acute ischemic brain stroke with ozone
US20100316730A1 (en) * 2003-07-31 2010-12-16 Latino Joseph S Treatment of cardiovascular diseases with ozone
JP5096148B2 (ja) * 2004-06-07 2012-12-12 コア・ダイナミクス・リミテッド 生物学的試料の殺菌方法
US20070134814A1 (en) * 2005-12-09 2007-06-14 Kajander E O Methods and compositions for the detection of calcifying nano-particles, identification and quantification of associated proteins thereon, and correlation to disease
WO2007106582A2 (en) * 2006-03-15 2007-09-20 Promethean Lifesciences, Inc. Preparation and storage of stable, biologically active materials
WO2008128161A2 (en) * 2007-04-13 2008-10-23 University Of Florida Research Foundation Inc. Identification of cardiac specific myosin light chain kinase
US11284616B2 (en) 2010-05-05 2022-03-29 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US9199016B2 (en) 2009-10-12 2015-12-01 New Health Sciences, Inc. System for extended storage of red blood cells and methods of use
US20110250670A1 (en) * 2010-04-08 2011-10-13 University Of Calcutta Light energy-induced stability of biomaterials
EP2555799B1 (en) * 2010-04-08 2018-03-07 University Of Calcutta Light energy-induced stability of biomaterials
EP4091645A1 (en) 2010-08-25 2022-11-23 Hemanext Inc. Method for enhancing red blood cell quality and survival during storage
EP4218412A1 (en) * 2010-11-05 2023-08-02 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US9067004B2 (en) 2011-03-28 2015-06-30 New Health Sciences, Inc. Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly
CN103732056B (zh) * 2011-07-05 2016-08-17 新健康科学股份有限公司 用于红细胞之延长贮藏的系统及使用方法
PT3533507T (pt) 2011-08-10 2022-07-25 Hemanext Inc Dispositivo de filtragem integrado para depleção de leucócitos, oxigénio e/ou co2 e separação de plasma
KR101446265B1 (ko) * 2011-10-17 2014-11-03 메디칸(주) 면역성이 제거된 생체지방소재 및 이의 제조방법
US9877476B2 (en) 2013-02-28 2018-01-30 New Health Sciences, Inc. Gas depletion and gas addition devices for blood treatment
JP6997622B2 (ja) 2015-03-10 2022-02-04 ヘマネクスト インコーポレイテッド 使い捨ての酸素低減キット、器具及びそれらの使用方法
JP7175611B2 (ja) 2015-04-23 2022-11-21 ヘマネクスト インコーポレイテッド 嫌気性血液保存容器
EP3297641A4 (en) 2015-05-18 2019-02-06 New Health Sciences, Inc. METHODS FOR TOTAL BLOOD STORAGE AND CORRESPONDING COMPOSITIONS
CN109195632A (zh) 2016-05-27 2019-01-11 新健康科学股份有限公司 厌氧血液储存和病原体失活方法
JP7110360B2 (ja) 2017-10-09 2022-08-01 テルモ ビーシーティー バイオテクノロジーズ,エルエルシー 凍結乾燥方法
WO2019126494A1 (en) * 2017-12-20 2019-06-27 Cook Regentec Llc Pathogen reduced platelet compositions and related methods
US11604026B2 (en) 2019-03-14 2023-03-14 Terumo Bct Biotechnologies, Llc Lyophilization loading tray assembly and system
AU2021262493A1 (en) * 2020-05-01 2022-12-08 Askel Healthcare Ltd. Method for preparing a three-dimensional scaffold for medical use

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179338A (en) * 1977-09-19 1979-12-18 Gordon Maurice R Microbiological medium suitable for sterilization by ionizing radiation
US4620908A (en) * 1983-10-03 1986-11-04 Biocell Laboratories, Inc. Method for destroying microbial contamination in protein materials
NL8700067A (nl) * 1986-02-07 1987-09-01 Argatom Ing Constr Werkwijze voor het verkrijgen van geconserveerd vlees.
US4866282A (en) * 1986-08-26 1989-09-12 Baxter International Inc. Irradiation of blood products
US4878891A (en) * 1987-06-25 1989-11-07 Baylor Research Foundation Method for eradicating infectious biological contaminants in body tissues
GB8807187D0 (en) * 1988-03-25 1988-04-27 Harrison J F Improvements in/relating to inactivation of infectious agents
US4874690A (en) * 1988-08-26 1989-10-17 Cryopharm Corporation Lyophilization of red blood cells
US5418130A (en) * 1990-04-16 1995-05-23 Cryopharm Corporation Method of inactivation of viral and bacterial blood contaminants
JP2894458B2 (ja) * 1990-08-02 1999-05-24 川澄化学工業 株式会社 検査用血液保存容器
JPH04285561A (ja) * 1991-03-14 1992-10-09 Terumo Corp 医療用材料の滅菌方法および医療用器具の製造方法
US5534026A (en) * 1992-04-02 1996-07-09 The Penn State Research Foundation Preparation of inexpensive, HIV-free human skin allograft
US5362442A (en) * 1993-07-22 1994-11-08 2920913 Canada Inc. Method for sterilizing products with gamma radiation
JP3765108B2 (ja) * 1994-09-30 2006-04-12 三菱ウェルファーマ株式会社 静脈注射用グロブリン製剤
ATE244024T1 (de) * 1996-02-05 2003-07-15 Asahi Medical Co Sterilisationsschutzmittel und verfahren zur sterilisation
JP3656242B2 (ja) * 1999-10-26 2005-06-08 スズキ株式会社 車両のモータ制御装置
US20030012687A1 (en) * 2000-03-23 2003-01-16 Macphee Martin J. Methods of sterilizing biological materials
US6682695B2 (en) * 2001-03-23 2004-01-27 Clearant, Inc. Methods for sterilizing biological materials by multiple rates
US6696060B2 (en) * 2001-06-14 2004-02-24 Clearant, Inc. Methods for sterilizing preparations of monoclonal immunoglobulins
US20030031584A1 (en) * 2001-08-10 2003-02-13 Wilson Burgess Methods for sterilizing biological materials using dipeptide stabilizers
US20030064000A1 (en) * 2001-09-24 2003-04-03 Wilson Burgess Methods of sterilizing biological mixtures using stabilizer mixtures
US20030190272A1 (en) * 2002-04-08 2003-10-09 Dennis Raine Sterilization containers and methods for radiation sterilization of liquid products

Also Published As

Publication number Publication date
AU2003237391B2 (en) 2007-08-30
ZA200409859B (en) 2006-08-30
WO2003103390A1 (en) 2003-12-18
MXPA04012771A (es) 2005-05-27
EP1511377A1 (en) 2005-03-09
US20040126880A1 (en) 2004-07-01
AU2003237391A1 (en) 2003-12-22
KR20070118200A (ko) 2007-12-13
JP2005533041A (ja) 2005-11-04
CN1665388A (zh) 2005-09-07
CA2487826A1 (en) 2003-12-18

Similar Documents

Publication Publication Date Title
BR0311824A (pt) Esterilização, estabilização e preservação de biológicos funcionais
US4623717A (en) Pasteurized therapeutically active protein compositions
US7494502B2 (en) Alteration of the skin and nail for the prevention and treatment of skin and nail infections
Drampalos et al. Single stage treatment of diabetic calcaneal osteomyelitis with an absorbable gentamicin-loaded calcium sulphate/hydroxyapatite biocomposite: The Silo technique
KR960703625A (ko) 제품의 살균방법(method for sterilizing products)
BRPI0515073A (pt) composição para conservação de madeira, e, método para conservar madeira
DE60201783D1 (de) Pharmazeutische Zusammensetzung enthaltend nicht-MHC-abhängige T-Zellen/NK-Zellen und MHC-abhängige Zellen zur Behandlung von Tumoren
BR0309890A (pt) Composição farmacêutica contendo plasma sanguìneo, ou soro sanguìneo utilizada no tratamento de lesões, bem como seu método e processo de aplicação
DE69433901D1 (de) Verbindungen und pharmazeutische zusammensetzungen zur behandlung und prophylaxe bakterieller infektionen
BR0209057A (pt) Composições herbicidas contendo benzoilciclohexanodionas e protetores
BR9712680A (pt) Composição e método para tratamento de plantas com substâncias quìmicas exógenas
CY1106771T1 (el) Φαρμακευτικη συνθεση η οποια χρησιμοποιειται για τον ελεγχο της γλυκοζης του αιματος σε ασθενεις με διαβητη τυπου 2
Persichini et al. Cysteine nitrosylation inactivates the HIV-1 protease
ATE92343T1 (de) Sterilisation von behaeltern mittels wasserstoffperoxid, persaeuren und uv-strahlung.
Takhtfooladi et al. Effects of light-emitting diode (LED) therapy on skeletal muscle ischemia reperfusion in rats
DK1187530T3 (da) Forbedret opbevaring og holdbarhed af blodprodukter
Reich et al. Sporicidal efficacy of genipin: a potential theoretical alternative for biomaterial and tissue graft sterilization
DE60109897D1 (de) Zur inaktivierung von infektiösen proteinen behandelte zusammensetzungen
CS445488A1 (en) Biological preparation for osteo- and chondropathies,physiopathological disorders and diseases arisen on base of mineral deficiency in human organism treatment
ATE499944T1 (de) Verwendung von einem extrakt von einem nicht- photosynthetischen faserigen bakterium zur beförderung der herstellung von superoxid- dismutase
CA2440914A1 (en) Process for sterilization of protein containing biological compositions
BR0110077A (pt) Compostos e composições antipicornavirais, seus usos farmacêuticos, e materiais para a sua sìntese
BR0312835A (pt) Derivado de ácido benzóico substituìdo por 3-heterociclila, agente, processos de combate de vegetação indesejada e de dessecação/desfolhamento de plantas, e, uso de derivados de ácido benzóico substituìdo por 3-heterociclila
US20070191793A1 (en) Method and material for reducing biofilm
Furuta et al. Radiation sterilization of enzyme hybrids with biodegradable polymers

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2157 DE 08/05/2012.