KR930004265A - 신규 치환 n-플루오로피리디늄술포네이트, 그의 중간체 및 그의 제조방법 - Google Patents

신규 치환 n-플루오로피리디늄술포네이트, 그의 중간체 및 그의 제조방법 Download PDF

Info

Publication number
KR930004265A
KR930004265A KR1019920013830A KR920013830A KR930004265A KR 930004265 A KR930004265 A KR 930004265A KR 1019920013830 A KR1019920013830 A KR 1019920013830A KR 920013830 A KR920013830 A KR 920013830A KR 930004265 A KR930004265 A KR 930004265A
Authority
KR
South Korea
Prior art keywords
alkyl
group
hydrogen atom
substituted
formula
Prior art date
Application number
KR1019920013830A
Other languages
English (en)
Other versions
KR100231610B1 (ko
Inventor
데루오 우메모또
긴지로 도미자와
Original Assignee
야마다 미노루
다이낑고오교 가부시끼가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 야마다 미노루, 다이낑고오교 가부시끼가이샤 filed Critical 야마다 미노루
Publication of KR930004265A publication Critical patent/KR930004265A/ko
Application granted granted Critical
Publication of KR100231610B1 publication Critical patent/KR100231610B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C07D213/71—Sulfur atoms to which a second hetero atom is attached
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)

Abstract

내용 없음.

Description

신규 치환 N-플루오로피리디늄술포네이트, 그의 중간체 및 그의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (10)

  1. 하기 식(Ⅰ)의 치환 N-플루오로피리디늄 술포네이트.
    [상기 식중, R1은 수소원자, 할로겐원자 또는 C1~C4알킬 또는 할로알킬기이고, R2은 C1~C4알킬 또는 할로알킬기이다].
  2. 제1항의 치환 N-플루오로피리디늄술포네이트로 구성된 플루오르화제.
  3. 하기 식(Ⅱ)의 이치환 피리딘-2-술폰산 또는 그의 염.
    [상기 식중, R2은 C1~C4알킬 또는 할로알킬이고, R3은 할로겐원자 또는 C1~C4알킬 또는 할로알킬기이며, M은 수소원자, 금속원소 또는 암모늄기이다].
  4. 하기 식(Ⅲ)의 할로알킬-치환 피리딘-2-술폰산 또는 그의 염.
    [상기 식중, R4은 C1~C4할로알킬기이며, M은 수소원자, 금속원소 또는 암모늄기이다].
  5. 하기 식(Ⅳ)의 알킬-치환 피리딘-2-술폰산 또는 그의 염.
    상기 식중, R5은 에틸기 또는 t-부틸기이고, M은 수소원자, 금속원소 또는 암모늄기이다].
  6. 하기 식(Ⅴ)의 치환 피리딘 술폰산을 하기 식(Ⅵ)의 아민 화합물의 존재하에 분자상 불소와 반응시킴을 특징으로 하는 제1항의 치환 N-플루오로피리디늄술포네이트(Ⅰ)의 제조방법.
    [상기 식중, R1은 수소원자, 할로겐원자 또는 C1~C4알킬 또는 할로알킬기이고, R2은 C1~C4알킬 또는 할로알킬기이며, R6,R7및 R8은 동일하거나 상이하며 각각은 수소원자 또는 C1~C8알킬 또는 아랄킬기이다].
  7. 하기 식(ⅩⅠ)의 치환 2-할로피리딘을 아황산염과 반응시키고 임의로 생성 화합물을 산으로 처리함을 특징으로 하는 하기 식(Ⅹ)의 치환 피리딘-2-술폰산 또는 그의 염의 제조방법.
    [상기 식중, R4은 C1~C4할로알킬기이고, R9은 수소원자, 할로겐원자 또는 C1~C4할로알킬기이며, M은 수소원자, 금속원소 또는 암모늄기이고, X은 할로겐원자이다].
  8. 제2항의 플루오르화제를 사용하여 화합물을 플루오르화하는 방법.
  9. 제8항에 있어서, 화합물이 유기 화합물인 방법.
  10. 제9항에 있어서, 유기 화합물이 친핵성 화합물인 방법.
    ※참고사항:최초출원 내용에 의하여 공개하는 것임.
KR1019920013830A 1991-08-01 1992-07-31 신규치환n-플루오로피리디늄술포네이트,그의중간체및그의제조방법 KR100231610B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP19298191 1991-08-01
JP91-192981 1991-08-01
JP3485492 1992-02-21
JP92-34854 1992-02-21

Publications (2)

Publication Number Publication Date
KR930004265A true KR930004265A (ko) 1993-03-22
KR100231610B1 KR100231610B1 (ko) 1999-11-15

Family

ID=26373722

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920013830A KR100231610B1 (ko) 1991-08-01 1992-07-31 신규치환n-플루오로피리디늄술포네이트,그의중간체및그의제조방법

Country Status (6)

Country Link
US (1) US5374732A (ko)
EP (1) EP0526849B1 (ko)
JP (1) JP3094677B2 (ko)
KR (1) KR100231610B1 (ko)
CA (1) CA2074991A1 (ko)
DE (1) DE69230358T2 (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0559660U (ja) * 1991-12-28 1993-08-06 京セラ株式会社 光ディスク
EP0787719B1 (en) * 1994-10-22 2001-08-16 Daikin Industries, Ltd. Conjugated n-fluoropyridinium salt polymer and use thereof
WO1997006170A1 (fr) * 1995-08-03 1997-02-20 Daikin Industries, Ltd. Procedes de production de sels de n,n'-difluorodiazoniabicyclo-alcanes, produits intermediaires utilises dans leur synthese, produits cibles et application des produits cibles
DE102004059916A1 (de) 2004-12-13 2006-06-14 Robert Bosch Gmbh Disc-Monopol-Antennenstruktur
WO2008119699A1 (en) 2007-03-30 2008-10-09 Fractus, S.A. Wireless device including a multiband antenna system
TWI753910B (zh) 2016-05-16 2022-02-01 美商拜歐斯瑞克斯公司 吡啶硫酮、其醫藥組合物及其治療增生性、炎性、神經退化性或免疫介導疾病之治療用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652574A (en) * 1984-11-14 1987-03-24 Nippon Kayaku Kabushiki Kaisha Certain mono-, di- or tri-substituted pyridyl esters of alkane sulfonic acids having insecticidal, acaricidal and nematocidal properties
US5081249A (en) * 1985-06-03 1992-01-14 Sagami Chemical Research Center N-fluoropyridinium-Sulfonates and a process for their preparation
CA1288777C (en) * 1985-06-03 1991-09-10 Teruo Umemoto N-fluoropyridinium salt and process for preparing same
JPH0233707A (ja) * 1988-07-22 1990-02-02 Hitachi Ltd フロッピディスク装置の制御方式および磁気記録媒体
JPH0819103B2 (ja) * 1989-04-18 1996-02-28 財団法人相模中央化学研究所 ２―ハロピリジン―６―スルホン酸及びその塩
US4935519A (en) * 1989-05-12 1990-06-19 Allied-Signal Inc. N-fluoropyridinium pyridine heptafluorodiborate
JPH0819105B2 (ja) * 1989-09-12 1996-02-28 財団法人相模中央化学研究所 Ｎ―フルオロピリジニウム―スルホナート

Also Published As

Publication number Publication date
JP3094677B2 (ja) 2000-10-03
JPH05294937A (ja) 1993-11-09
DE69230358T2 (de) 2000-05-11
KR100231610B1 (ko) 1999-11-15
EP0526849A1 (en) 1993-02-10
US5374732A (en) 1994-12-20
DE69230358D1 (de) 2000-01-05
CA2074991A1 (en) 1993-02-02
EP0526849B1 (en) 1999-12-01

Similar Documents

Publication Publication Date Title
KR860003206A (ko) 벤조일 페닐우레아의 제조방법
DE3773089D1 (de) Verfahren zur herstellung von thiazolidinedion-derivaten.
KR870002125A (ko) 피리딘 유도체의 제조방법
KR870003989A (ko) 치환 및 이치환 피리딘-2,3-디카르복실레이트의 제조방법과 치환된 니코티네이트의 제조방법
KR840005098A (ko) 피리딜(옥시/티오) 페녹시 화합물의 제조방법
KR870002056A (ko) 치환된 프로파르길옥시아세토니트릴 유도체의 제조 방법
KR860000243A (ko) 아민유도체의 제조방법
KR930004265A (ko) 신규 치환 n-플루오로피리디늄술포네이트, 그의 중간체 및 그의 제조방법
KR860006427A (ko) 신규한 탄화수소계 화합물의 제조방법
KR830006302A (ko) 신규 피리미딘 유도체의 제조방법
KR890002188A (ko) 술펜아미드 유도체 및 그의 제조방법
DE3887579D1 (de) Mercapto-substituierte Pyridine und Verfahren zu deren Herstellung.
KR860001814A (ko) 이미다조〔1.2-a〕퀴놀린 유도체의 제조방법
KR840000526A (ko) 니코티노일 벤조구아나민유도체 및 그 산부가염류의 제조방법
KR920000767A (ko) 2-페닐-6-(피리미딘-2-일) 피리딘 유도체의 제조방법, 여기에 사용된 중간 화합물, 및 이것의 제조방법
KR910011842A (ko) 피리딜옥시피리미딘 유도체들 및 이들의 제조방법과 활성성분으로서 이들을 포함하는 제초제 조성물
KR840006478A (ko) 벤조 트리아졸의 제조방법
KR910011845A (ko) 2-푸릴피리미딘 유도체의 제조방법
KR960022468A (ko) 클로로메틸피리딘의 제조방법
KR910000746A (ko) 1, 1-디옥소페닐실리노일 옥시메틸 d-6-[x-(메틸렌 아미노)페닐-아세트아미도]-페니실라네이트와 그의 파라-톨루엔술폰산염
KR890002011A (ko) 5-할로 게노-6-아미노-니코틴산 할라이드. 이의 제조방법 및 용도
KR880001635A (ko) 5-플루오로우라실 유도체, 그의 제조방법 및 용도
KR860003224A (ko) N-벤조일 페닐 우레아의 제조방법
KR890006595A (ko) 디할로겐 치환 티오시아노 피리미딘 유도체, 그의 제조방법 및 농원예용 살균제
KR860002473A (ko) 4-메틸-5-티오포름아미디노메틸이미다졸 디하이드로클로라이드의 제조방법

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 20080825

Year of fee payment: 10

LAPS Lapse due to unpaid annual fee