KR927003535A - 7-클로로퀴놀린-8-카르복실산의 정제 방법 - Google Patents

7-클로로퀴놀린-8-카르복실산의 정제 방법 Download PDF

Info

Publication number
KR927003535A
KR927003535A KR1019920701839A KR920701839A KR927003535A KR 927003535 A KR927003535 A KR 927003535A KR 1019920701839 A KR1019920701839 A KR 1019920701839A KR 920701839 A KR920701839 A KR 920701839A KR 927003535 A KR927003535 A KR 927003535A
Authority
KR
South Korea
Prior art keywords
carboxylic acid
chloroquinoline
base
process according
purifying
Prior art date
Application number
KR1019920701839A
Other languages
English (en)
Other versions
KR100325558B1 (ko
Inventor
게르노트 라이쎈베버
크누트 코브
빈프리드 리샤르쯔
Original Assignee
바르쯔, 스타인호프
바스프 악티엔게젤샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 바르쯔, 스타인호프, 바스프 악티엔게젤샤프트 filed Critical 바르쯔, 스타인호프
Publication of KR927003535A publication Critical patent/KR927003535A/ko
Application granted granted Critical
Publication of KR100325558B1 publication Critical patent/KR100325558B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Quinoline Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Forms Removed On Construction Sites Or Auxiliary Members Thereof (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

내용 없음

Description

7-클로로퀴놀린-8-카르복실산의 정제 방법
[도면의 간단한 설명]
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (5)

  1. 물과 혼화성인 저급 알코올에 의해 재결정시킴으로써 일반식(I)과 7-클로로퀴놀린-8-카르복실산을 정제하는 방법에 있어서, 재결정을 소량의 염기 존재하에 수행함을 특징으로 하는 방법.
    식중, X는 수소, 할겐, 또는 저급 알킬기이다.
  2. 제1항에 있어서, 알칼리 금속 또는 알칼리 토금속 수산화물을 염기로서 사용함을 특징으로 하는 방법.
  3. 제1항 또는 2항에 있어서, 1-메톡시-2-프로판올을 용매로서 사용함을 특징으로 하는 방법.
  4. 제3항에 있어서, 재결정화되는 퀴놀린카르복실산을 계의 자생 압력하에 130내지 170℃에서 용해시킴을 특징으로 하는 방법.
  5. 제1항 내지 제4항중 어느 한 항에 있어서, 정제되는 7-클로로-8-퀴놀린 카르복실산을 기준으로 0.1 내지 1중랑%의 염기를 사용함을 특징으로 하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019920701839A 1990-02-03 1991-01-25 7-클로로퀴놀린-8-카르복실산의정제방법 KR100325558B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4003174A DE4003174A1 (de) 1990-02-03 1990-02-03 Verfahren zur reinigung von 7-chlor-chinolin-8-carbonsaeuren
DEP4003174.8 1990-02-03
PCT/EP1991/000143 WO1991011436A1 (de) 1990-02-03 1991-01-25 Verfahren zur reinigung von 7-chlor-chinolin-8-carbonsäuren

Publications (2)

Publication Number Publication Date
KR927003535A true KR927003535A (ko) 1992-12-18
KR100325558B1 KR100325558B1 (ko) 2002-08-14

Family

ID=6399333

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920701839A KR100325558B1 (ko) 1990-02-03 1991-01-25 7-클로로퀴놀린-8-카르복실산의정제방법

Country Status (11)

Country Link
US (1) US5310915A (ko)
EP (1) EP0513056B1 (ko)
JP (1) JP2957273B2 (ko)
KR (1) KR100325558B1 (ko)
AT (1) ATE130852T1 (ko)
CA (1) CA2068429C (ko)
DE (2) DE4003174A1 (ko)
DK (1) DK0513056T3 (ko)
ES (1) ES2080294T3 (ko)
GR (1) GR3018488T3 (ko)
WO (1) WO1991011436A1 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102796042A (zh) * 2012-06-13 2012-11-28 江苏绿利来股份有限公司 一种催化氧化合成二氯喹啉酸的方法
CN102796043B (zh) * 2012-06-13 2014-08-27 江苏绿利来股份有限公司 一种二氯喹啉酸盐的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3108873A1 (de) * 1981-03-09 1982-09-16 Basf Ag, 6700 Ludwigshafen Dichlorchinolinderivate, ihre herstellung, ihre verwendung als herbizide und mittel dafuer
DE3202736A1 (de) * 1982-01-28 1983-08-04 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von chinolinmonocarbonsaeuren
US4497651A (en) * 1982-02-17 1985-02-05 Basf Aktiengesellschaft Dichloroquinoline derivatives for use as herbicides
DE3703113A1 (de) * 1987-02-03 1988-08-11 Basf Ag Verfahren zur herstellung von substituierten 3-alkyl-chinolin-8-carbonsaeuren
EP0282778B1 (de) * 1987-03-03 1992-05-13 BASF Aktiengesellschaft Verfahren zur Herstellung von 7-Chlor-chinolin-8-carbonsäuren

Also Published As

Publication number Publication date
US5310915A (en) 1994-05-10
DE59106994D1 (de) 1996-01-11
ES2080294T3 (es) 1996-02-01
WO1991011436A1 (de) 1991-08-08
JPH05503932A (ja) 1993-06-24
CA2068429A1 (en) 1991-08-04
ATE130852T1 (de) 1995-12-15
DE4003174A1 (de) 1991-08-08
EP0513056A1 (de) 1992-11-19
JP2957273B2 (ja) 1999-10-04
DK0513056T3 (da) 1995-12-27
CA2068429C (en) 2002-04-16
GR3018488T3 (en) 1996-03-31
EP0513056B1 (de) 1995-11-29
KR100325558B1 (ko) 2002-08-14

Similar Documents

Publication Publication Date Title
KR850000406A (ko) 4-클로로-2-페닐이미다졸-5-아세트산유도체의 제조방법
KR850006939A (ko) 아실트리펩타이드의 제조방법
KR840004106A (ko) 4급 6,11-디하이드로-디벤조-[b,e]-티에핀-11-N-알킬-노르스코핀 에테르의 제조방법
KR830006228A (ko) 이미다졸 유도체의 제조방법
KR860000243A (ko) 아민유도체의 제조방법
KR830007626A (ko) 2-(1,4-벤조디옥산-2-일알킬) 이미다졸류의 제조방법
KR860003239A (ko) 퀴놀론 카복실산 유도체의 제조방법
KR927003535A (ko) 7-클로로퀴놀린-8-카르복실산의 정제 방법
KR870001191A (ko) 퀴논론카복실산 유도체의 제조방법
KR870007127A (ko) 퀴놀론 카복실산 유도체의 제조방법
KR880011103A (ko) 5-아미노-4,6-디할로게노피리딘의 제조방법
KR830004320A (ko) 퀴나졸린 유도체의 제조방법
KR840004053A (ko) 페닐알카노산의 제조방법
KR830007693A (ko) 7-아미노 세펨 화합물을 제조하는 개량방법
KR840002406A (ko) 3위치가 티오메틸 복소환 그룹에 의해 치환된 신규의 세팔로스포린유도체의 제조방법세
KR830009043A (ko) 4-(1-이미다졸일메틸)신남산 하이드로클로라이드 모노하이드레이트의 제조방법
KR840000901A (ko) 옥센돌론 수성 현탁제의 제조방법
KR870003093A (ko) 퀴놀론카복실산 유도체의 제조방법
KR920019742A (ko) L-프롤린 유도체의 제조방법
KR900018123A (ko) 광학적 활성인 d-2-n-펜아세틸아미노-4-메틸 포스피노부티르산의 라세미화 방법
KR830001890A (ko) 카바졸 유도체의 제조방법
KR840003639A (ko) 이속사졸로피리미딘 유도체의 제조방법
KR950008482A (ko) 1,2,3,4-테트라히드로퀴놀린-8-술폰산 클로라이드 및 산, 그의 제법과 합성중간체로서 그의 사용
KR850006428A (ko) 에리드로마이신 아세트산염의 제조방법
KR920009792A (ko) 3-아미노-4-메틸렌피롤리딘 유도체의 제조방법

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E601 Decision to refuse application
J201 Request for trial against refusal decision
J301 Trial decision

Free format text: TRIAL DECISION FOR APPEAL AGAINST DECISION TO DECLINE REFUSAL REQUESTED 19981230

Effective date: 19990410

J2X1 Appeal (before the patent court)

Free format text: APPEAL AGAINST DECISION TO DECLINE REFUSAL

J2X2 Appeal (before the supreme court)

Free format text: APPEAL BEFORE THE SUPREME COURT FOR APPEAL AGAINST DECISION TO DECLINE REFUSAL

J303 Written judgement (supreme court)

Free format text: JUDGMENT (SUPREME COURT) FOR APPEAL AGAINST DECISION TO DECLINE REFUSAL REQUESTED 19991115

Effective date: 20010925

J302 Written judgement (patent court)

Free format text: JUDGMENT (PATENT COURT) FOR APPEAL AGAINST DECISION TO DECLINE REFUSAL REQUESTED 19990514

Effective date: 19991028

J301 Trial decision

Free format text: TRIAL DECISION FOR APPEAL AGAINST DECISION TO DECLINE REFUSAL REQUESTED 20011022

Effective date: 20011116

S901 Examination by remand of revocation
GRNO Decision to grant (after opposition)
GRNT Written decision to grant
G170 Re-publication after modification of scope of protection [patent]
FPAY Annual fee payment

Payment date: 20100204

Year of fee payment: 9

EXPY Expiration of term