KR920008744B1 - Hiv 감염의 치료 및 진단용 모노클로날항체 및 펩티드 - Google Patents

Hiv 감염의 치료 및 진단용 모노클로날항체 및 펩티드 Download PDF

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Publication number
KR920008744B1
KR920008744B1 KR1019870009058A KR870009058A KR920008744B1 KR 920008744 B1 KR920008744 B1 KR 920008744B1 KR 1019870009058 A KR1019870009058 A KR 1019870009058A KR 870009058 A KR870009058 A KR 870009058A KR 920008744 B1 KR920008744 B1 KR 920008744B1
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KR
South Korea
Prior art keywords
hiv
peptide
antibody
amino acid
monoclonal antibodies
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Expired
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KR1019870009058A
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English (en)
Korean (ko)
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KR890002547A (ko
Inventor
캐틀린 스리버 매리
케이. 토머스 엘레인
엘. 코산드 웨슬리
에이치. 고스팅 라리
에스 딕킨슨 에드나
먹클루어 제넬라(엔엠아이)
제이. 토라도 조지
씨. 노윈스키 로버트
Original Assignee
제네틱 시스팀스 코포레이션
아이삭 자아코브스키
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Publication of KR890002547A publication Critical patent/KR890002547A/ko
Application granted granted Critical
Publication of KR920008744B1 publication Critical patent/KR920008744B1/ko
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Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B25/00Multi-stage pumps
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036Retroviridae, e.g. leukemia viruses
    • C07K16/1045Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1054Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • C12Q1/703Viruses associated with AIDS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16211Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • AIDS & HIV (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Mechanical Engineering (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1019870009058A 1986-08-20 1987-08-19 Hiv 감염의 치료 및 진단용 모노클로날항체 및 펩티드 Expired KR920008744B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US89827386A 1986-08-20 1986-08-20
US898273 1986-08-20
US4502687A 1987-05-01 1987-05-01
US45026 1987-05-01
US6799687A 1987-06-29 1987-06-29
US67996 1987-06-29

Publications (2)

Publication Number Publication Date
KR890002547A KR890002547A (ko) 1989-04-10
KR920008744B1 true KR920008744B1 (ko) 1992-10-09

Family

ID=27366600

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019870009058A Expired KR920008744B1 (ko) 1986-08-20 1987-08-19 Hiv 감염의 치료 및 진단용 모노클로날항체 및 펩티드

Country Status (28)

Country Link
JP (1) JPS6485928A (enrdf_load_stackoverflow)
KR (1) KR920008744B1 (enrdf_load_stackoverflow)
AT (1) AT398080B (enrdf_load_stackoverflow)
AU (1) AU616156B2 (enrdf_load_stackoverflow)
BE (1) BE1000811A4 (enrdf_load_stackoverflow)
CH (1) CH675728A5 (enrdf_load_stackoverflow)
CS (1) CS275838B6 (enrdf_load_stackoverflow)
DE (1) DE3727703A1 (enrdf_load_stackoverflow)
DK (1) DK433087A (enrdf_load_stackoverflow)
ES (1) ES2010727A6 (enrdf_load_stackoverflow)
FI (1) FI873553L (enrdf_load_stackoverflow)
FR (1) FR2603107B1 (enrdf_load_stackoverflow)
GB (1) GB2196634B (enrdf_load_stackoverflow)
GR (1) GR871298B (enrdf_load_stackoverflow)
HU (1) HU214439B (enrdf_load_stackoverflow)
IE (1) IE60671B1 (enrdf_load_stackoverflow)
IL (1) IL83580A (enrdf_load_stackoverflow)
IT (1) IT1222518B (enrdf_load_stackoverflow)
LU (1) LU86972A1 (enrdf_load_stackoverflow)
NL (1) NL8701950A (enrdf_load_stackoverflow)
NO (2) NO300462B1 (enrdf_load_stackoverflow)
NZ (1) NZ221440A (enrdf_load_stackoverflow)
OA (1) OA08652A (enrdf_load_stackoverflow)
PL (1) PL155084B1 (enrdf_load_stackoverflow)
PT (1) PT85567B (enrdf_load_stackoverflow)
SE (1) SE506025C2 (enrdf_load_stackoverflow)
YU (1) YU152587A (enrdf_load_stackoverflow)
ZW (1) ZW15487A1 (enrdf_load_stackoverflow)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP96A (en) * 1986-06-03 1990-08-12 The Usa Dept Of Commerce Small peptides which inhibit binding to T-4 receptors and act as immunogens.
AU625720B2 (en) * 1987-05-01 1992-07-16 Genetic Systems Corporation Monoclonal antibodies to specific antigenic regions of the human immunodeficiency virus and methods for use
US6657050B1 (en) 1987-05-29 2003-12-02 Tanox, Inc. Chimeric viral-neutralizing immunoglobulins
US5981278A (en) * 1987-05-29 1999-11-09 Tanox, Inc. Chimeric monoclonal antibodies which neutralize HIV-1 infection and their applications in therapy and prevention for AIDS
US5834599A (en) * 1987-05-29 1998-11-10 Tanox Biosystems, Inc. Immunoconjugates which neutralize HIV-1 infection
JP2520464B2 (ja) * 1987-05-29 1996-07-31 タノツクス・バイオシステムズ・インコーポレーテツド Hiv―1を中和するモノクロ―ナル抗体
JP2569185B2 (ja) * 1988-01-26 1997-01-08 アメリカ合衆国 抗hiv応答を喚起する合成抗原
CA1341285C (en) * 1988-02-12 2001-08-14 Chang Yi Wang Synthetic peptides for the detection of antibodies to hiv gp120 envelope protein for diagnosis of aids and pre-aids conditions and as vaccines
IL90048A0 (en) * 1988-04-25 1989-12-15 Merck & Co Inc Recombinant gag precursor of hiv,its preparation and its use as aids vaccine
EP0339504A3 (en) * 1988-04-26 1990-09-12 The Du Pont Merck Pharmaceutical Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
US5562905A (en) * 1988-04-26 1996-10-08 E. I. Du Pont De Nemours And Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
FR2632310B1 (fr) * 1988-06-06 1992-04-10 Pasteur Institut Peptides ayant des proprietes protectrices d'un virus pathogene du type hiv dans des cellules sensibles
FI911574A7 (fi) * 1988-10-03 1991-04-02 Repligen Corp Uusia HIV-proteiineja ja -peptidejä, jotka ovat käyttökelpoisia aidsin toteamisessa, ennaltaehkäisyssä ja hoidossa
CA2025481A1 (en) * 1989-09-19 1991-03-20 Peter J. Kniskern Vaccine for aids and hepatitis b
SE9000333D0 (sv) * 1990-01-31 1990-01-31 Britta Wahren Monoklonal antikropp
SE468168B (sv) * 1990-02-20 1992-11-16 Replico Medical Ab Hiv-1, p24 peptider, diagnostiska antigener och foerfarande foer saerskiljande diagnostik av preliminaert hiv-1 positiva serumprov
JPH03271233A (ja) * 1990-03-19 1991-12-03 Inst Pasteur ウイルスエンベロープ糖タンパク質及びその糖タンパク質の中和エピトープに対応するペプチドの間の相乗作用による、ウイルス性感染に対する防御の誘発
CA2047042A1 (en) * 1990-07-19 1992-01-20 John Hannah Cyclic hiv principal neutralizing determinant peptides
CA2047078A1 (en) * 1990-07-19 1992-01-20 Steven S. Bondy Cyclic hiv principal neutralizing determinant peptides
JPH05310785A (ja) * 1991-09-30 1993-11-22 Nitto Denko Corp Hiv関連環状ペプチドおよびこれを固定化した吸着体
DE69333537T2 (de) * 1992-03-27 2005-06-16 Advanced Immuni T, Inc. T-peptid und damit verwandte Peptide in der Behandlung von entzündungen einschlies slich der Multiplen Sklerose
PL1976548T3 (pl) 2005-12-09 2015-01-30 Vectus Biosystems Ltd Fragmenty VIP i ich kompozycje
US8253311B2 (en) 2008-09-02 2012-08-28 Ngk Spark Plug Co., Ltd Spark plug
KR102727239B1 (ko) * 2022-09-07 2024-11-07 한국세라믹기술원 산화 마그네슘 분말 및 그의 제조방법

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9328391B1 (en) * 1984-08-22 2016-05-03 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Cloning and expression of HIV-1 DNA
EP0201540B2 (en) * 1984-10-18 2001-10-31 Institut Pasteur Envelope antigens of lymphadenopathy associated virus and their applications
GB8501473D0 (en) * 1985-01-21 1985-02-20 Pasteur Institut Cloned dna sequences
CA1341423C (en) * 1984-10-31 2003-03-04 Paul A. Luciw Recombinant proteins of viruses associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome
EP0220234B1 (en) * 1985-04-08 1994-08-03 Genetic Systems Corporation EXPRESSION AND DIAGNOSTIC USE OF gag ENCODED PEPTIDES WHICH ARE IMMUNOLOGICALLY REACTIVE WITH ANTIBODIES TO LAV
IE64785B1 (en) * 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
NZ215867A (en) * 1985-04-19 1989-10-27 Hoffmann La Roche Aids envelope protein, dna vectors and method of production
EP0220273B2 (en) * 1985-04-29 2007-01-17 Bio-Rad Laboratories, Inc. Synthetic antigens for the detection of aids-related disease
GB8525615D0 (en) * 1985-10-17 1985-11-20 Hoffmann La Roche Polypeptides
JPS63501716A (ja) * 1985-10-24 1988-07-14 サウスウエスト・ファウンデ−ション・フォア・バイオメディカル・リサ−チ 合成ペプチドおよびaidsおよびarcの診断ならびにワクチン注射へのその使用
WO1987002988A1 (en) * 1985-11-07 1987-05-21 President And Fellows Of Harvard College T-cell lymphotrophic virus protein and assay
US4772547A (en) * 1986-02-03 1988-09-20 Hoffmann-La Roche Inc. HTLV-III envelope peptides
US4734362A (en) * 1986-02-03 1988-03-29 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof
US4925784A (en) * 1986-04-04 1990-05-15 Hoffmann-La Roche Inc. Expression and purification of an HTLV-III gag/env gene protein
DK169582B1 (da) * 1986-06-23 1994-12-12 Squibb Bristol Myers Co Humant monoklonalt antistof, der er i stand til at reagere med en epitop på LAV/HTLV-III kappeglycoproteinet gp41, cellelinier, som producerer sådant antistof, farmaceutisk præparat indeholdende antistoffet samt fremgangsmåde til bestemmelse af nærværelsen af LAV/HTLV-III i en biologisk prøve og fremgangsmåde til separering af specifikke antigendeterminanter af LAV/HTLV-III under anvendelse af ant
EP0255190A3 (en) * 1986-08-01 1990-08-29 Repligen Corporation Recombinant polypeptides and their uses, inclusing assay for aids virus
WO1988005051A1 (en) * 1986-12-30 1988-07-14 United States Of America, Represented By The Unite Synthetic peptides which induce cellular immunity of the aids virus and aids viral proteins

Also Published As

Publication number Publication date
FI873553A7 (fi) 1988-02-21
IT8721678A0 (it) 1987-08-19
CS275838B6 (en) 1992-03-18
IL83580A (en) 1992-11-15
AU616156B2 (en) 1991-10-24
NO934897L (no) 1993-12-29
IE872219L (en) 1988-02-20
NO873495D0 (no) 1987-08-19
GB2196634A (en) 1988-05-05
HU214439B (hu) 1998-03-30
NO873495L (no) 1988-02-22
SE506025C2 (sv) 1997-11-03
JPS6485928A (en) 1989-03-30
SE8703225D0 (sv) 1987-08-19
ZW15487A1 (en) 1988-09-14
NO934897D0 (no) 1993-12-29
BE1000811A4 (fr) 1989-04-11
IE60671B1 (en) 1994-08-10
GB2196634B (en) 1991-05-15
NO300462B1 (no) 1997-06-02
NL8701950A (nl) 1988-03-16
IL83580A0 (en) 1988-01-31
NO302176B1 (no) 1998-02-02
KR890002547A (ko) 1989-04-10
DK433087A (da) 1988-02-21
AT398080B (de) 1994-09-26
NZ221440A (en) 1991-11-26
AU7720187A (en) 1988-05-19
YU152587A (sh) 1992-09-07
ES2010727A6 (es) 1989-12-01
PT85567A (en) 1987-09-01
PL267401A1 (en) 1988-07-21
DE3727703A1 (de) 1988-05-05
FR2603107B1 (fr) 1992-04-24
OA08652A (fr) 1988-11-30
LU86972A1 (fr) 1988-03-02
DK433087D0 (da) 1987-08-19
ATA208987A (de) 1994-01-15
CH675728A5 (enrdf_load_stackoverflow) 1990-10-31
FI873553L (fi) 1988-02-21
PT85567B (pt) 1991-02-08
FI873553A0 (fi) 1987-08-17
PL155084B1 (en) 1991-10-31
GB8719587D0 (en) 1987-09-23
HUT44619A (en) 1988-03-28
SE8703225L (sv) 1988-02-21
IT1222518B (it) 1990-09-05
GR871298B (en) 1988-01-12
FR2603107A1 (fr) 1988-02-26
CS8706136A2 (en) 1990-08-14

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