KR910018554A - 발효법에 의한 d-이소구연산 (d-isocitric acid)의 제조방법 - Google Patents

발효법에 의한 d-이소구연산 (d-isocitric acid)의 제조방법 Download PDF

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KR910018554A
KR910018554A KR1019910005260A KR910005260A KR910018554A KR 910018554 A KR910018554 A KR 910018554A KR 1019910005260 A KR1019910005260 A KR 1019910005260A KR 910005260 A KR910005260 A KR 910005260A KR 910018554 A KR910018554 A KR 910018554A
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South Korea
Prior art keywords
candida
acid
isocitric acid
producing
isocitric
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KR1019910005260A
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KR940010304B1 (ko
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구니기 기노
야스히로 도미요시
요시유끼 구라쓰
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가또오 미끼오
교와 학꼬 고오교오 가부시끼가이샤
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/48—Tricarboxylic acids, e.g. citric acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/165—Yeast isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/72—Candida

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

내용 없음.

Description

발효법에 의한 d-이소구연산(d-isocitric acid)의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. 칸디다 속에 속하고, 모노후루오르 아세트산에 내성을 갖으며, 유일 탄소원인 d-이소구연산 존재하에서 생육불능이거나 또는 미약한 정도로만 생육 가능하고, d-이소구연산 생산능력을 갖는 미생물을, 배지중에서 배양액중에 d-이소구연산이 축적될때까지 배양하고, 배양역으로 부터 d-이소구연산을 회수하는 것이 특징인 발표법에 의한 d-이소구연산 제조방법.
  2. 제1항에 있어서, 상기 미생물이, 칸디다 리폴리티카, 칸디다 제일라노이데스, 칸디다 기아몬디, 칸디다 달비칸스, 칸디다 휴미콜라, 칸디다 파라실로시스 종, 또는 칸디다 브람프티종에 속하는 것이 특징인 발표법에 의한 d-이소구연산 제조방법.
  3. 제2항에 있어서, 상기 미생물이, 칸디다 제일 라노이데스 H-7728(FERM BP-2756)인 것이 특징인 발표법에 의한 d-이소구연산 제조방법.
  4. 칸디다 제일 라노이데스 H-7728(FERM BP-2756)의 생물학적으로 순수한 배양물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개되는 것임.
KR1019910005260A 1990-04-03 1991-04-02 발효법에 의한 d-이소구연산(d-isocitric acid)의 제조방법 KR940010304B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2-88876 1990-04-03
JP08887690A JP3165688B2 (ja) 1990-04-03 1990-04-03 発酵法によるｄ―イソクエン酸の製造法

Publications (2)

Publication Number Publication Date
KR910018554A true KR910018554A (ko) 1991-11-30
KR940010304B1 KR940010304B1 (ko) 1994-10-22

Family

ID=13955208

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019910005260A KR940010304B1 (ko) 1990-04-03 1991-04-02 발효법에 의한 d-이소구연산(d-isocitric acid)의 제조방법

Country Status (7)

Country Link
EP (1) EP0450491B1 (ko)
JP (1) JP3165688B2 (ko)
KR (1) KR940010304B1 (ko)
DE (1) DE69116198T2 (ko)
DK (1) DK0450491T3 (ko)
HU (1) HU210212B (ko)
IL (1) IL97672A (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012024435A1 (de) 2012-12-14 2014-07-10 Forschungszentrum Jülich GmbH Verfahren zur Identifizierung einer Zelle mit gegenüber ihrem Wildtyp erhöhten intrazellulären Konzentration eines bestimmten Metaboliten, wobei die Veränderung der Zelle durch Rekombi-neering erreicht wird, sowie ein Verfahren zur Herstellung einer gegenüber ihrem Wildtyp genetisch veränderten Produktionszelle mit optimierter Produktion eines bestimmten Metaboliten, ein Verfahren zur Herstellung dieses Metaboliten, sowie dafür geeignete Nukleinsäuren
CN110455975B (zh) * 2019-07-26 2021-12-07 成都青山利康药业有限公司 一种枸橼酸钠原料和/或含枸橼酸钠的药物中杂质的检测方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2065206A1 (de) * 1969-10-09 1972-11-02 Kyowa Hakko Kogyo Co. Ltd., Tokio Verfahren zur Herstellung von Citronensäure und Isocitronensäure auf mikrobiologischem Wege. Ausscheidung aus: 2048356
US3801455A (en) * 1971-07-02 1974-04-02 Takeda Chemical Industries Ltd Method for producing citric acid

Also Published As

Publication number Publication date
HUT61596A (en) 1993-01-28
KR940010304B1 (ko) 1994-10-22
DE69116198T2 (de) 1996-09-19
IL97672A0 (en) 1992-06-21
JPH03290195A (ja) 1991-12-19
EP0450491A3 (en) 1992-06-10
DE69116198D1 (de) 1996-02-22
DK0450491T3 (da) 1996-05-28
HU911081D0 (en) 1991-10-28
EP0450491A2 (en) 1991-10-09
JP3165688B2 (ja) 2001-05-14
IL97672A (en) 1995-07-31
EP0450491B1 (en) 1996-01-10
HU210212B (en) 1995-02-28

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