KR900018033A - 나프탈렌프로피온산 염 - Google Patents
나프탈렌프로피온산 염 Download PDFInfo
- Publication number
- KR900018033A KR900018033A KR1019890016130A KR890016130A KR900018033A KR 900018033 A KR900018033 A KR 900018033A KR 1019890016130 A KR1019890016130 A KR 1019890016130A KR 890016130 A KR890016130 A KR 890016130A KR 900018033 A KR900018033 A KR 900018033A
- Authority
- KR
- South Korea
- Prior art keywords
- carbon atoms
- amine
- hydroxyalkyl
- hydrogen
- compound
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (7)
- α-메틸-6-(2-퀴놀리닐메톡시)-2-나프탈렌아세트산, 아민 염[여기서, 아민은 일반식 NR1R2R3(여기서, R1은 수소, 페닐, 탄소수 1 내지 6의 알킬 또는 탄소수 1 내지 6의 하이드록시알킬이고, R2는 수소, 탄소수 1 내지 6의 하이드록시알킬이며, R3은 탄소수 1 내지 12의 하이드록시알킬이다)의 하이드록시알킬아민이다).
- S(+)-α-메틸-6-(2-퀴놀리닐메톡시)-2-나프탈렌 아세트산, 아민 염[여기서, 아민은 제1항에서 정의한 바와 같은 일반식 NR1R2R3의 하이드록시알킬아민이다).
- R(-)-α-메틸-6-(2-퀴놀리닐메톡시)-2-나프탈렌 아세트산, 아민 염[여기서, 아민은 제1항에서 정의한 바와 같은 일반식 NR1R2R3의 하이드록시알킬아민이다).
- 제1항 내지 3항중 어느 한 항에 있어서, R1및 R2가 1개 내지 3개의 탄소원자를 갖는 알킬 또는 하이드록시알킬 그룹이고, R3이 1개 내지 6개의 탄소원자를 갖는 하이드록시알킬 그룹인 화합물.
- 제1항 내지 4항중 어느 한 항에 있어서, 그룹R3이 폴리하이드록시 알킬 그룹인 화합물.
- 제1항 내지 3항중 어느 한항에 있어서, R1및 R2가 수소인 화합물.
- 제6항에 있어서, 아민이 트로메트아민인 화합물.※ 참고사항 : 최초출원내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US351,119 | 1989-05-12 | ||
US07/351,119 US4960892A (en) | 1988-06-10 | 1989-05-12 | Naphthalenepropionic acid derivatives as anti-inflammatory/anti-allergic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
KR900018033A true KR900018033A (ko) | 1990-12-20 |
Family
ID=23379653
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019890016130A KR900018033A (ko) | 1989-05-12 | 1989-11-08 | 나프탈렌프로피온산 염 |
Country Status (15)
Country | Link |
---|---|
US (1) | US4960892A (ko) |
EP (1) | EP0396839B1 (ko) |
JP (1) | JPH02311463A (ko) |
KR (1) | KR900018033A (ko) |
AT (1) | ATE104281T1 (ko) |
AU (1) | AU629868B2 (ko) |
CA (1) | CA1331001C (ko) |
DE (1) | DE68914646T2 (ko) |
DK (1) | DK169545B1 (ko) |
ES (1) | ES2063143T3 (ko) |
GB (1) | GB2231570B (ko) |
IE (1) | IE61967B1 (ko) |
IL (1) | IL92083A0 (ko) |
NZ (1) | NZ231255A (ko) |
ZA (1) | ZA898291B (ko) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5084575A (en) * | 1987-07-31 | 1992-01-28 | American Home Products Corporation | Quinoline substituted naphthalenepropionic acid derivatives as anti-inflammatory/antiallergic agents |
US5208344A (en) * | 1987-07-31 | 1993-05-04 | American Home Products Corporation | Naphthalenepropionic acid derivatives as anti-inflammatory/antiallergic agents |
JPH0317061A (ja) * | 1989-06-13 | 1991-01-25 | Kyorin Pharmaceut Co Ltd | 新規環状アントラニル酸酢酸誘導体 |
EP0540165A1 (en) * | 1991-10-03 | 1993-05-05 | Zeneca Limited | Alkanoic acid derivatives |
ES2058024B1 (es) * | 1992-11-10 | 1995-05-01 | Menarini Lab | Nuevo derivado arilpropionico, procedimiento de fabricacion del mismo y su utilizacion como analgesico. |
ES2124196B1 (es) * | 1997-06-04 | 1999-12-01 | Menarini Lab | Procedimiento para la fabricacion de una forma farmaceutica semisolida conteniendo dexketoprofeno trometamol y su utilizacion en el tratamiento topico de la inflamacion. |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3904682A (en) * | 1967-01-13 | 1975-09-09 | Syntex Corp | 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid |
DE2134672A1 (de) * | 1971-07-08 | 1973-01-25 | Josef Dipl Chem Dr Rer N Klosa | Wasserloesliches acetylsalicylsaeuresalz, dessen herstellung, zubereitung und anwendung |
US4097674A (en) * | 1975-03-17 | 1978-06-27 | Syntex Corporation | 2-Naphthylacetic acid derivatives |
HU185926B (en) * | 1979-09-27 | 1985-04-28 | Agostne Kahan | Process for preparing water soluble derivatives of non-steroid antiinflammatory compositions and pharmaceutical compositins containing such derivatives |
AT370721B (de) * | 1981-02-24 | 1983-04-25 | Ciba Geigy Ag | Verfahren zur herstellung von neuen salzen der 2- (2,6-dichloranilino)-phenylessigsaeure, der |
US4794188A (en) * | 1982-12-01 | 1988-12-27 | Usv Pharmaceutical Corporation | Certain unsymmetrical quinolinyl ethers having anti-inflammatory and anti-allergic activity |
US4661596A (en) * | 1985-02-21 | 1987-04-28 | American Home Products Corporation | Quinolinyl (or pyridinyl) methoxy substituted naphthalene compounds as antiallergic agents |
US4631287A (en) * | 1985-04-16 | 1986-12-23 | Usv Pharmaceutical Corp. | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
US4754043A (en) * | 1985-10-03 | 1988-06-28 | American Home Products Corporation | Oxazole and thiazole naphthalenes as antiallergic agents |
US4732978A (en) * | 1985-10-03 | 1988-03-22 | American Home Products Corporation | Novel substituted naphthyloxymethyl quinoline derivatives as anti-inflammatory and antiallergy agents |
US4772703A (en) * | 1986-01-27 | 1988-09-20 | American Home Products Corporation | 2-(phenoxymethyl)-quinazolines as antiallergic and antiinflammatory agents |
AU611699B2 (en) * | 1987-07-31 | 1991-06-20 | American Home Products Corporation | Naphthalene propionic acid derivatives |
IL133435A0 (en) * | 1997-06-12 | 2001-04-30 | Northrop Grumman Corp | Heat resistant composite structure |
-
1989
- 1989-05-12 US US07/351,119 patent/US4960892A/en not_active Expired - Lifetime
- 1989-09-26 CA CA000613074A patent/CA1331001C/en not_active Expired - Fee Related
- 1989-10-23 IL IL92083A patent/IL92083A0/xx not_active IP Right Cessation
- 1989-10-26 JP JP1279615A patent/JPH02311463A/ja active Pending
- 1989-10-31 ES ES89311231T patent/ES2063143T3/es not_active Expired - Lifetime
- 1989-10-31 EP EP89311231A patent/EP0396839B1/en not_active Expired - Lifetime
- 1989-10-31 AT AT89311231T patent/ATE104281T1/de active
- 1989-10-31 GB GB8924501A patent/GB2231570B/en not_active Expired - Fee Related
- 1989-10-31 DE DE68914646T patent/DE68914646T2/de not_active Expired - Fee Related
- 1989-10-31 ZA ZA898291A patent/ZA898291B/xx unknown
- 1989-11-01 IE IE351989A patent/IE61967B1/en not_active IP Right Cessation
- 1989-11-03 NZ NZ231255A patent/NZ231255A/xx unknown
- 1989-11-03 AU AU44361/89A patent/AU629868B2/en not_active Ceased
- 1989-11-08 KR KR1019890016130A patent/KR900018033A/ko not_active Application Discontinuation
-
1990
- 1990-05-10 DK DK117590A patent/DK169545B1/da not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0396839A3 (en) | 1991-06-05 |
EP0396839B1 (en) | 1994-04-13 |
JPH02311463A (ja) | 1990-12-27 |
DK117590A (da) | 1990-11-13 |
DK169545B1 (da) | 1994-11-28 |
IE893519L (en) | 1990-11-12 |
IL92083A0 (en) | 1990-07-12 |
CA1331001C (en) | 1994-07-26 |
DE68914646D1 (de) | 1994-05-19 |
DE68914646T2 (de) | 1994-07-21 |
ZA898291B (en) | 1991-06-26 |
US4960892A (en) | 1990-10-02 |
GB2231570B (en) | 1992-05-20 |
AU4436189A (en) | 1990-11-15 |
NZ231255A (en) | 1991-02-26 |
ATE104281T1 (de) | 1994-04-15 |
GB2231570A (en) | 1990-11-21 |
EP0396839A2 (en) | 1990-11-14 |
ES2063143T3 (es) | 1995-01-01 |
DK117590D0 (da) | 1990-05-10 |
GB8924501D0 (en) | 1989-12-20 |
IE61967B1 (en) | 1994-11-30 |
AU629868B2 (en) | 1992-10-15 |
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