KR930000528A - 아미노피롤리딘 백금화합물 및 그 제조방법 - Google Patents
아미노피롤리딘 백금화합물 및 그 제조방법 Download PDFInfo
- Publication number
- KR930000528A KR930000528A KR1019920009568A KR920009568A KR930000528A KR 930000528 A KR930000528 A KR 930000528A KR 1019920009568 A KR1019920009568 A KR 1019920009568A KR 920009568 A KR920009568 A KR 920009568A KR 930000528 A KR930000528 A KR 930000528A
- Authority
- KR
- South Korea
- Prior art keywords
- aminopyrrolidine
- platinum compound
- manufacturing
- aminopyrrolidine platinum
- platinum compounds
- Prior art date
Links
- LEKAINPIBRLOPK-UHFFFAOYSA-N platinum;pyrrolidin-1-amine Chemical class [Pt].NN1CCCC1 LEKAINPIBRLOPK-UHFFFAOYSA-N 0.000 title claims 6
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 239000012736 aqueous medium Substances 0.000 claims 1
- 229910052700 potassium Inorganic materials 0.000 claims 1
- 239000011591 potassium Substances 0.000 claims 1
- SBMSLRMNBSMKQC-UHFFFAOYSA-N pyrrolidin-1-amine Chemical compound NN1CCCC1 SBMSLRMNBSMKQC-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (4)
- 일반식(I)으로 이루어진 아미노피롤리딘 백금화합물 :상기식에서, R는 1-12 탄소원자수를 갖는 선형 알킬기이며, R1는 1-3 탄소원자수를 갖는 선형 알킬기이다.
- 제1항에 있어서, 적어도 한 아미노피롤리딘 백금화합물이 의약중량제 및/또는 보조제와 함께 의약조성물에 사용되는 아미노 피롤리딘 백금화합물.
- 제1항에 있어서, 종양치료를 위한 의약조성물 제조에 사용되는 아미노피롤리딘 백금화합물.
- 포타슘테트라클로로플라티나이트와 일반식(II)의 아미노 피롤리딘을 반응시켜서 아미노피롤리딘 백금화합물을 제조하는 방법 :상기식에서, R 및 R1는 수용성 매질에서 일반식(I)에 대해 규정된 것과 같다.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES09101355A ES2042364B1 (es) | 1991-06-05 | 1991-06-05 | Procedimiento de obtencion de nuevos derivados de platino con aminopirrolidinas. |
| ES9101355 | 1991-06-05 | ||
| ES09201002A ES2056721B1 (es) | 1991-06-05 | 1992-05-14 | Mejoras en el objeto de la patente de invencion n{ 9101355 que se refiere a procedimiento de obtencion de nuevos derivados de platino con aminopirrolidinas. |
| ES9201002 | 1992-05-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR930000528A true KR930000528A (ko) | 1993-01-15 |
| KR950007337B1 KR950007337B1 (ko) | 1995-07-10 |
Family
ID=26154552
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019920009568A KR950007337B1 (ko) | 1991-06-05 | 1992-06-02 | 아미노피롤리딘 백금화합물 및 그 제조방법 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0517225A1 (ko) |
| JP (1) | JPH05178872A (ko) |
| KR (1) | KR950007337B1 (ko) |
| CA (1) | CA2070508A1 (ko) |
| ES (1) | ES2056721B1 (ko) |
| IE (1) | IE921732A1 (ko) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2182482C1 (ru) * | 2000-09-19 | 2002-05-20 | РДИнновейшн Апс | Способ получения противоопухолевого средства |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU193809B (en) * | 1984-09-12 | 1987-12-28 | Chugai Pharmaceutical Co Ltd | Process for producing new platinum complexes |
| ATE86967T1 (de) * | 1988-01-09 | 1993-04-15 | Asta Medica Ag | 1,2-bis(aminomethyl)cyclobutan-platin-komplexe. |
| JPH01294683A (ja) * | 1988-02-04 | 1989-11-28 | Kanebo Ltd | 新規白金錯体および該化合物を有効成分とする抗腫瘍剤並びに該化合物製造用中間体 |
| AT392273B (de) * | 1988-04-07 | 1991-02-25 | Chugai Pharmaceutical Co Ltd | Verfahren zur herstellung von platinkomplexen |
-
1992
- 1992-05-14 ES ES09201002A patent/ES2056721B1/es not_active Expired - Fee Related
- 1992-06-02 KR KR1019920009568A patent/KR950007337B1/ko active IP Right Grant
- 1992-06-04 EP EP92109480A patent/EP0517225A1/en not_active Ceased
- 1992-06-04 CA CA002070508A patent/CA2070508A1/en not_active Abandoned
- 1992-06-05 JP JP4145925A patent/JPH05178872A/ja active Pending
- 1992-07-01 IE IE173292A patent/IE921732A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR950007337B1 (ko) | 1995-07-10 |
| IE921732A1 (en) | 1992-12-16 |
| JPH05178872A (ja) | 1993-07-20 |
| CA2070508A1 (en) | 1992-12-06 |
| ES2056721A1 (es) | 1994-10-01 |
| ES2056721B1 (es) | 1995-05-01 |
| EP0517225A1 (en) | 1992-12-09 |
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| A201 | Request for examination | ||
| E902 | Notification of reason for refusal | ||
| G160 | Decision to publish patent application | ||
| E701 | Decision to grant or registration of patent right | ||
| NORF | Unpaid initial registration fee |