KR900011757A - 피리디늄 니트레이트, 그의 제조방법 및 용도 - Google Patents
피리디늄 니트레이트, 그의 제조방법 및 용도 Download PDFInfo
- Publication number
- KR900011757A KR900011757A KR1019900001020A KR900001020A KR900011757A KR 900011757 A KR900011757 A KR 900011757A KR 1019900001020 A KR1019900001020 A KR 1019900001020A KR 900001020 A KR900001020 A KR 900001020A KR 900011757 A KR900011757 A KR 900011757A
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- formula
- general formula
- following general
- inhibiting
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (5)
- 하기 일반식(I)의 화합물.
- (a)활성 성분으로서, 혈소판 활성화 인자의 활성을 억제하기 위한 유효량의 제1항에 다르는 화합물, 및 (b)제약학적으로 허용 가능한 담체 또는 부형제를 함유함을 특징으로 하는, 혈소판 활성화 인자의 활성을 억제하는데 적합한 제약학적 조성물.
- 혈소판 활성화 인자의 활성을 억제하기 위한 유효량의 제1항 화합물을 포유 동물에 투여함을 특징으로하는 포유 동물의 혈소판 활성화 인자의 활성 억제 방법.
- 제1항에 따르는 화합물의 포유 동물의 치료처지를 위한 용도.
- I)하기 일반식(II)의 화합물을 하기 일반식(III)의 화합물과 반응시킨 후 NO3-이온을 도입하거나,[상기 식중, Q1는 질소 원자에 용이하게 치환되는 기를 나타낸다.] II)하기 일반식(IV)의 화합물과 하기 일반식(V)의 화합물을 탈수 축합시키거나,III)하기 일반식(VI)의 화합물과 하기 일반식(VII)의 화합물을 탈수 축합시키거나,IV)하기 일반식(VIII)의 화합물을 하기 일반식(IX)의 화합물과 반응시키거나,[상기 식중, G는 할로게노 또는 페녹시기이다.]V)하기 일반식(X)의 화합물을 하기 일반식(XI)의 화합물과 반응시키는 것을 특징으로 하는 제1항의 화합물의 제조방법.[상기 식중, G는 할로게노 또는 페녹시기이다.]※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP021919-1989 | 1989-01-30 | ||
JP1-21919 | 1989-01-30 | ||
JP2191989 | 1989-01-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR900011757A true KR900011757A (ko) | 1990-08-02 |
KR0143413B1 KR0143413B1 (ko) | 1998-07-15 |
Family
ID=12068486
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019900001020A KR0143413B1 (ko) | 1989-01-30 | 1990-01-30 | 피리디늄 니트 레이트, 그의 제조방법 및 용도 |
Country Status (9)
Country | Link |
---|---|
US (1) | US4981860A (ko) |
EP (1) | EP0382380B1 (ko) |
JP (1) | JP2765155B2 (ko) |
KR (1) | KR0143413B1 (ko) |
AT (1) | ATE93855T1 (ko) |
CA (1) | CA2008771C (ko) |
DE (1) | DE69002959T2 (ko) |
DK (1) | DK0382380T3 (ko) |
ES (1) | ES2058779T3 (ko) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2068742B1 (es) * | 1993-02-11 | 1995-11-16 | Uriach & Cia Sa J | Nuevos derivados de piridinio. |
US5496855A (en) * | 1995-01-27 | 1996-03-05 | Smithkline Beecham Corp. | Anti-inflammatory compounds |
AU5514196A (en) * | 1995-04-27 | 1996-11-18 | Takeda Chemical Industries Ltd. | Agent for severe acute pancreatitis |
WO1998004547A1 (en) * | 1996-07-25 | 1998-02-05 | Takeda Chemical Industries, Ltd. | Crystalline pyridinium derivatives as paf-antagonists |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK160818C (da) * | 1983-12-30 | 1991-10-07 | Hoffmann La Roche | N-ring-holdige glycerolderivater, fremgangsmaade til fremstilling deraf, anvendelse deraf til fremstilling af et blodpladeaktiveringsfaktorhaemmende middel samt laegemidler indeholdende en saadan forbindelse |
DE3879024T2 (de) * | 1987-07-31 | 1993-10-07 | Takeda Chemical Industries Ltd | Pyridinium-Derivate, ihre Herstellung und Verwendung. |
-
1990
- 1990-01-25 US US07/470,244 patent/US4981860A/en not_active Expired - Fee Related
- 1990-01-26 DE DE90300837T patent/DE69002959T2/de not_active Expired - Fee Related
- 1990-01-26 ES ES90300837T patent/ES2058779T3/es not_active Expired - Lifetime
- 1990-01-26 DK DK90300837.3T patent/DK0382380T3/da active
- 1990-01-26 AT AT90300837T patent/ATE93855T1/de not_active IP Right Cessation
- 1990-01-26 EP EP90300837A patent/EP0382380B1/en not_active Expired - Lifetime
- 1990-01-29 CA CA002008771A patent/CA2008771C/en not_active Expired - Fee Related
- 1990-01-30 KR KR1019900001020A patent/KR0143413B1/ko not_active IP Right Cessation
- 1990-01-30 JP JP2020842A patent/JP2765155B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE93855T1 (de) | 1993-09-15 |
KR0143413B1 (ko) | 1998-07-15 |
EP0382380B1 (en) | 1993-09-01 |
EP0382380A1 (en) | 1990-08-16 |
US4981860A (en) | 1991-01-01 |
DE69002959D1 (de) | 1993-10-07 |
DE69002959T2 (de) | 1994-03-24 |
JP2765155B2 (ja) | 1998-06-11 |
DK0382380T3 (da) | 1994-01-10 |
JPH02275876A (ja) | 1990-11-09 |
CA2008771A1 (en) | 1990-07-30 |
ES2058779T3 (es) | 1994-11-01 |
CA2008771C (en) | 1999-03-23 |
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E902 | Notification of reason for refusal | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
LAPS | Lapse due to unpaid annual fee |