NO913023L - Nye bicykliske aminosubstituerte forbindelser - Google Patents
Nye bicykliske aminosubstituerte forbindelserInfo
- Publication number
- NO913023L NO913023L NO91913023A NO913023A NO913023L NO 913023 L NO913023 L NO 913023L NO 91913023 A NO91913023 A NO 91913023A NO 913023 A NO913023 A NO 913023A NO 913023 L NO913023 L NO 913023L
- Authority
- NO
- Norway
- Prior art keywords
- compounds
- pct
- aminosubstituted
- alkyl
- new bicyclic
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
- C07C45/515—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an acetalised, ketalised hemi-acetalised, or hemi-ketalised hydroxyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Reproductive Health (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyrane Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO940861A NO177901C (no) | 1989-12-07 | 1994-03-10 | Substituerte 2-aminotetraliner og fremgangsmåte for deres fremstilling |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8904127A SE8904127D0 (sv) | 1989-12-07 | 1989-12-07 | New biocyclic amino-substituted compounds |
| PCT/SE1990/000806 WO1991009006A1 (en) | 1989-12-07 | 1990-12-05 | New bicyclic amino-substituted compounds |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO913023L true NO913023L (no) | 1991-08-02 |
| NO913023D0 NO913023D0 (no) | 1991-08-02 |
| NO176018B NO176018B (no) | 1994-10-10 |
| NO176018C NO176018C (no) | 1995-01-18 |
Family
ID=20377709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO913023A NO176018C (no) | 1989-12-07 | 1991-08-02 | Analogifremgangsmåte for fremstilling av terapeutisk aktive S-enantiomerer av substituerte 2-aminotetraliner |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5376687A (no) |
| EP (1) | EP0457883B1 (no) |
| JP (1) | JPH04503819A (no) |
| KR (1) | KR920701122A (no) |
| AT (1) | ATE137490T1 (no) |
| AU (1) | AU639742B2 (no) |
| CA (1) | CA2046292A1 (no) |
| DE (1) | DE69026816T2 (no) |
| DK (1) | DK0457883T3 (no) |
| ES (1) | ES2086528T3 (no) |
| FI (1) | FI913713A0 (no) |
| GR (1) | GR3020122T3 (no) |
| LT (1) | LT4035B (no) |
| LV (1) | LV10607B (no) |
| NO (1) | NO176018C (no) |
| RU (1) | RU2086537C1 (no) |
| SE (1) | SE8904127D0 (no) |
| WO (1) | WO1991009006A1 (no) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2691149B1 (fr) * | 1992-05-18 | 1994-07-08 | Adir | Nouveaux composes thiochromaniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. |
| IT1278045B1 (it) * | 1995-03-09 | 1997-11-17 | Sigma Tau Ind Farmaceuti | Uso di 2-amminotetraline-6,7-sostituite per la preparazione di composizioni farmaceutiche atte al trattamento dello shock, e di |
| US5646188A (en) * | 1995-07-05 | 1997-07-08 | Teva Pharmaceutical Industries, Ltd. | Polyamine derivatives of 1-aminoindan |
| US5807897A (en) * | 1996-03-01 | 1998-09-15 | Zeneca Limited | Aminotetralin derivative and compositions and method of use thereof |
| US6844368B1 (en) | 1998-12-22 | 2005-01-18 | Edward Roberts | Compounds useful in pain management |
| US6498196B1 (en) | 1998-12-22 | 2002-12-24 | Edward Roberts | Compounds useful in pain management |
| AU3092800A (en) * | 1998-12-22 | 2000-07-12 | Astra Pharma Inc. | Novel thio-aminotetralin compounds useful in pain management |
| CN1674880A (zh) * | 2002-08-15 | 2005-09-28 | 惠氏公司 | 用于治疗体温调节机能障碍的5HT2a受体的激动作用 |
| US20050032873A1 (en) * | 2003-07-30 | 2005-02-10 | Wyeth | 3-Amino chroman and 2-amino tetralin derivatives |
| WO2007088450A2 (en) * | 2006-02-01 | 2007-08-09 | Pfizer Products Inc. | Chromane antagonist of the h-3 receptor |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2803582A1 (de) * | 1978-01-27 | 1979-08-02 | Sandoz Ag | Neue tetralinderivate, ihre herstellung und verwendung |
| SE8004002L (sv) * | 1980-05-29 | 1981-11-30 | Arvidsson Folke Lars Erik | Terapeutiskt anvendbara tetralinderivat |
| DE3679378D1 (de) * | 1985-09-03 | 1991-06-27 | Ciba Geigy Ag | 3-amino-dihydro-(1)-benzopyrane und benzothiopyrane. |
| CA1331191C (en) * | 1988-03-25 | 1994-08-02 | Bengt Ronny Andersson | Therapeutically useful tetralin derivatives |
| CA1335591C (en) * | 1988-05-23 | 1995-05-16 | James Arthur Nixon | Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes |
| KR910700225A (ko) * | 1989-01-09 | 1991-03-14 | 로버트 에이. 아미테이지 | 할로 치환된 아미노테트랄린 |
| US5225596A (en) * | 1989-01-09 | 1993-07-06 | The Upjohn Company | Halo substituted aminotetralins |
| DE69032725T2 (de) * | 1989-05-31 | 1999-04-08 | Pharmacia & Upjohn Co., Kalamazoo, Mich. | ZNS-wirksame 8-Heterocyclyl-2-aminotetralin Derivate |
-
1989
- 1989-12-07 SE SE8904127A patent/SE8904127D0/xx unknown
-
1990
- 1990-12-05 US US07/741,438 patent/US5376687A/en not_active Expired - Fee Related
- 1990-12-05 DK DK91900976.1T patent/DK0457883T3/da active
- 1990-12-05 EP EP91900976A patent/EP0457883B1/en not_active Expired - Lifetime
- 1990-12-05 FI FI913713A patent/FI913713A0/fi not_active Application Discontinuation
- 1990-12-05 ES ES91900976T patent/ES2086528T3/es not_active Expired - Lifetime
- 1990-12-05 AT AT91900976T patent/ATE137490T1/de not_active IP Right Cessation
- 1990-12-05 RU SU905001681A patent/RU2086537C1/ru active
- 1990-12-05 KR KR1019910700844A patent/KR920701122A/ko not_active Ceased
- 1990-12-05 DE DE69026816T patent/DE69026816T2/de not_active Expired - Fee Related
- 1990-12-05 WO PCT/SE1990/000806 patent/WO1991009006A1/en not_active Ceased
- 1990-12-05 CA CA002046292A patent/CA2046292A1/en not_active Abandoned
- 1990-12-05 JP JP3501388A patent/JPH04503819A/ja active Pending
- 1990-12-05 AU AU69587/91A patent/AU639742B2/en not_active Ceased
-
1991
- 1991-08-02 NO NO913023A patent/NO176018C/no unknown
-
1993
- 1993-07-30 LV LVP-93-1008A patent/LV10607B/en unknown
- 1993-12-30 LT LTIP1733A patent/LT4035B/lt not_active IP Right Cessation
-
1996
- 1996-05-31 GR GR960401501T patent/GR3020122T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH04503819A (ja) | 1992-07-09 |
| NO176018C (no) | 1995-01-18 |
| KR920701122A (ko) | 1992-08-11 |
| ES2086528T3 (es) | 1996-07-01 |
| RU2086537C1 (ru) | 1997-08-10 |
| SE8904127D0 (sv) | 1989-12-07 |
| LTIP1733A (en) | 1995-08-25 |
| DE69026816T2 (de) | 1996-10-02 |
| AU639742B2 (en) | 1993-08-05 |
| FI913713A7 (fi) | 1991-08-05 |
| AU6958791A (en) | 1991-07-18 |
| EP0457883A1 (en) | 1991-11-27 |
| WO1991009006A1 (en) | 1991-06-27 |
| US5376687A (en) | 1994-12-27 |
| LV10607A (lv) | 1995-04-20 |
| DE69026816D1 (de) | 1996-06-05 |
| ATE137490T1 (de) | 1996-05-15 |
| LV10607B (en) | 1995-12-20 |
| LT4035B (en) | 1996-09-25 |
| GR3020122T3 (en) | 1996-08-31 |
| CA2046292A1 (en) | 1991-06-08 |
| NO913023D0 (no) | 1991-08-02 |
| EP0457883B1 (en) | 1996-05-01 |
| DK0457883T3 (da) | 1996-08-26 |
| NO176018B (no) | 1994-10-10 |
| FI913713A0 (fi) | 1991-08-05 |
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