KR900004694B1 - 신규 α-아릴-α-피리딜 알카노인산 유도체의 제조방법 - Google Patents

신규 α-아릴-α-피리딜 알카노인산 유도체의 제조방법 Download PDF

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Publication number
KR900004694B1
KR900004694B1 KR1019830004386A KR830004386A KR900004694B1 KR 900004694 B1 KR900004694 B1 KR 900004694B1 KR 1019830004386 A KR1019830004386 A KR 1019830004386A KR 830004386 A KR830004386 A KR 830004386A KR 900004694 B1 KR900004694 B1 KR 900004694B1
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KR
South Korea
Prior art keywords
compound
pyridyl
aryl
test
preparing
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KR1019830004386A
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English (en)
Korean (ko)
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KR840006238A (ko
Inventor
이꾸오 우에다
마사노부 나가노
아쓰시 아까하네
Original Assignee
후지사와 야꾸힝 고교 가부시끼가이샤
후지사와 도모기찌로
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Publication of KR840006238A publication Critical patent/KR840006238A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57—Nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56—Amides

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
KR1019830004386A 1982-09-30 1983-09-19 신규 α-아릴-α-피리딜 알카노인산 유도체의 제조방법 Expired KR900004694B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP57172936A JPS5980664A (ja) 1982-09-30 1982-09-30 α−アリ−ル−α−ピリジル脂肪酸誘導体およびその製法
JP172936/1982 1982-09-30
JP172936/1982? 1982-09-30

Publications (2)

Publication Number Publication Date
KR840006238A KR840006238A (ko) 1984-11-22
KR900004694B1 true KR900004694B1 (ko) 1990-07-02

Family

ID=15951089

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830004386A Expired KR900004694B1 (ko) 1982-09-30 1983-09-19 신규 α-아릴-α-피리딜 알카노인산 유도체의 제조방법

Country Status (14)

Country Link
US (1) US4564621A (Projectiles-308-BTHP-Match-168grs-Version-500-pieces--item-5993058.html)
EP (1) EP0105458B1 (Projectiles-308-BTHP-Match-168grs-Version-500-pieces--item-5993058.html)
JP (1) JPS5980664A (Projectiles-308-BTHP-Match-168grs-Version-500-pieces--item-5993058.html)
KR (1) KR900004694B1 (Projectiles-308-BTHP-Match-168grs-Version-500-pieces--item-5993058.html)
AT (1) ATE48130T1 (Projectiles-308-BTHP-Match-168grs-Version-500-pieces--item-5993058.html)
CA (1) CA1246573A (Projectiles-308-BTHP-Match-168grs-Version-500-pieces--item-5993058.html)
DE (1) DE3380876D1 (Projectiles-308-BTHP-Match-168grs-Version-500-pieces--item-5993058.html)
DK (1) DK157854C (Projectiles-308-BTHP-Match-168grs-Version-500-pieces--item-5993058.html)
ES (1) ES8603421A1 (Projectiles-308-BTHP-Match-168grs-Version-500-pieces--item-5993058.html)
FI (1) FI80878C (Projectiles-308-BTHP-Match-168grs-Version-500-pieces--item-5993058.html)
GR (1) GR78525B (Projectiles-308-BTHP-Match-168grs-Version-500-pieces--item-5993058.html)
HU (1) HU193046B (Projectiles-308-BTHP-Match-168grs-Version-500-pieces--item-5993058.html)
NO (1) NO162017C (Projectiles-308-BTHP-Match-168grs-Version-500-pieces--item-5993058.html)
ZA (1) ZA837069B (Projectiles-308-BTHP-Match-168grs-Version-500-pieces--item-5993058.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60112762A (ja) * 1983-11-21 1985-06-19 Fujisawa Pharmaceut Co Ltd α−アリ−ル−α−ピリジル脂肪酸誘導体およびその製法
US4810703A (en) * 1984-10-19 1989-03-07 A. H. Robins Company, Incorporated 1-((aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-alpha, alpha-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles
US4783537A (en) * 1985-11-13 1988-11-08 Pennwalt Corporation α-(aminoalkyl)-arylacetic acid derivatives
US5202331A (en) * 1990-04-18 1993-04-13 Fujisawa Pharmaceutical Co., Ltd. Therapeutic agent for dysuria comprising alpha-phenyl-alpha-pyridylalkanoic acid derivatives
JP5000841B2 (ja) * 2001-01-24 2012-08-15 カディラ ヘルスケア リミティド クロピドグレルの製造方法
US8748433B2 (en) 2010-04-30 2014-06-10 Merck Sharp & Dohme Corp. β3 adrenergic receptor agonists

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA501690A (en) * 1954-04-20 Schering Corporation Pyridyl substituted alkanes
NL70757C (Projectiles-308-BTHP-Match-168grs-Version-500-pieces--item-5993058.html) * 1947-10-13
FR1235903A (fr) * 1954-06-04 1960-11-10 Pharmacia Ab Procédé de préparation d'amides butyriles
US2991289A (en) * 1958-02-05 1961-07-04 Merck Ag E Derivatives of 1-aminopropane
GB915804A (en) * 1958-04-12 1963-01-16 Degussa Process for the production of basically substituted carboxylic acid amides
FR2485M (fr) * 1961-05-17 1964-04-27 Searle & Co Nouveaux régulateurs cardiaques.
US3225054A (en) * 1962-07-03 1965-12-21 Searle & Co 4-dipropylamino-2-aryl-2-pyridylalkanamides
JPS5248862B2 (Projectiles-308-BTHP-Match-168grs-Version-500-pieces--item-5993058.html) * 1971-08-16 1977-12-13

Also Published As

Publication number Publication date
FI80878B (fi) 1990-04-30
ES526026A0 (es) 1985-12-16
ATE48130T1 (de) 1989-12-15
FI80878C (fi) 1990-08-10
DK421183A (da) 1984-03-31
JPS635025B2 (Projectiles-308-BTHP-Match-168grs-Version-500-pieces--item-5993058.html) 1988-02-01
FI833369A7 (fi) 1984-03-31
EP0105458B1 (en) 1989-11-23
DE3380876D1 (en) 1989-12-28
ES8603421A1 (es) 1985-12-16
ZA837069B (en) 1984-05-30
KR840006238A (ko) 1984-11-22
HU193046B (en) 1987-08-28
DK421183D0 (da) 1983-09-15
EP0105458A2 (en) 1984-04-18
JPS5980664A (ja) 1984-05-10
NO162017B (no) 1989-07-17
EP0105458A3 (en) 1985-11-27
US4564621A (en) 1986-01-14
NO833529L (no) 1984-04-02
DK157854B (da) 1990-02-26
NO162017C (no) 1989-10-25
CA1246573A (en) 1988-12-13
FI833369A0 (fi) 1983-09-21
GR78525B (Projectiles-308-BTHP-Match-168grs-Version-500-pieces--item-5993058.html) 1984-09-27
DK157854C (da) 1990-07-23

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