DK421183A - Fremgangsmaade til fremstilling af alfa-aryl-alfa-pyridylalkansyrer - Google Patents

Fremgangsmaade til fremstilling af alfa-aryl-alfa-pyridylalkansyrer Download PDF

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Publication number
DK421183A
DK421183A DK421183A DK421183A DK421183A DK 421183 A DK421183 A DK 421183A DK 421183 A DK421183 A DK 421183A DK 421183 A DK421183 A DK 421183A DK 421183 A DK421183 A DK 421183A
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DK
Denmark
Prior art keywords
sup
lower alkyl
alfa
hydrogen
aryl
Prior art date
Application number
DK421183A
Other languages
English (en)
Other versions
DK157854B (da
DK157854C (da
DK421183D0 (da
Inventor
Ikuo Ueda
Masanobu Nagano
Atsushi Akahane
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of DK421183D0 publication Critical patent/DK421183D0/da
Publication of DK421183A publication Critical patent/DK421183A/da
Publication of DK157854B publication Critical patent/DK157854B/da
Application granted granted Critical
Publication of DK157854C publication Critical patent/DK157854C/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57Nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56Amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK421183A 1982-09-30 1983-09-15 Analogifremgangsmaade til fremstilling af alfa-aryl-alfa-(2-pyridyl)-alkansyrederivater DK157854C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP57172936A JPS5980664A (ja) 1982-09-30 1982-09-30 α−アリ−ル−α−ピリジル脂肪酸誘導体およびその製法
JP17293682 1982-09-30

Publications (4)

Publication Number Publication Date
DK421183D0 DK421183D0 (da) 1983-09-15
DK421183A true DK421183A (da) 1984-03-31
DK157854B DK157854B (da) 1990-02-26
DK157854C DK157854C (da) 1990-07-23

Family

ID=15951089

Family Applications (1)

Application Number Title Priority Date Filing Date
DK421183A DK157854C (da) 1982-09-30 1983-09-15 Analogifremgangsmaade til fremstilling af alfa-aryl-alfa-(2-pyridyl)-alkansyrederivater

Country Status (14)

Country Link
US (1) US4564621A (da)
EP (1) EP0105458B1 (da)
JP (1) JPS5980664A (da)
KR (1) KR900004694B1 (da)
AT (1) ATE48130T1 (da)
CA (1) CA1246573A (da)
DE (1) DE3380876D1 (da)
DK (1) DK157854C (da)
ES (1) ES526026A0 (da)
FI (1) FI80878C (da)
GR (1) GR78525B (da)
HU (1) HU193046B (da)
NO (1) NO162017C (da)
ZA (1) ZA837069B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60112762A (ja) * 1983-11-21 1985-06-19 Fujisawa Pharmaceut Co Ltd α−アリ−ル−α−ピリジル脂肪酸誘導体およびその製法
US4810703A (en) * 1984-10-19 1989-03-07 A. H. Robins Company, Incorporated 1-((aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-alpha, alpha-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles
US4783537A (en) * 1985-11-13 1988-11-08 Pennwalt Corporation α-(aminoalkyl)-arylacetic acid derivatives
US5202331A (en) * 1990-04-18 1993-04-13 Fujisawa Pharmaceutical Co., Ltd. Therapeutic agent for dysuria comprising alpha-phenyl-alpha-pyridylalkanoic acid derivatives
CA2436323C (en) * 2001-01-24 2012-02-21 Cadila Healthcare Ltd. Process for preparing clopidogrel
EP2563123B1 (en) 2010-04-30 2018-04-25 Merck Sharp & Dohme Corp. Novel beta 3 adrenergic receptor agonists

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA501690A (en) * 1954-04-20 Schering Corporation Pyridyl substituted alkanes
NL70757C (da) * 1947-10-13
GB771814A (en) * 1954-06-04 1957-04-03 Pharmacia Ab New butyryl amides and processes for their manufacture
US2991289A (en) * 1958-02-05 1961-07-04 Merck Ag E Derivatives of 1-aminopropane
GB915804A (en) * 1958-04-12 1963-01-16 Degussa Process for the production of basically substituted carboxylic acid amides
FR2485M (fr) * 1961-05-17 1964-04-27 Searle & Co Nouveaux régulateurs cardiaques.
US3225054A (en) * 1962-07-03 1965-12-21 Searle & Co 4-dipropylamino-2-aryl-2-pyridylalkanamides
JPS5248862B2 (da) * 1971-08-16 1977-12-13

Also Published As

Publication number Publication date
FI80878C (fi) 1990-08-10
EP0105458A3 (en) 1985-11-27
NO162017C (no) 1989-10-25
GR78525B (da) 1984-09-27
FI80878B (fi) 1990-04-30
DK157854B (da) 1990-02-26
DK157854C (da) 1990-07-23
ATE48130T1 (de) 1989-12-15
HU193046B (en) 1987-08-28
JPS635025B2 (da) 1988-02-01
DE3380876D1 (en) 1989-12-28
KR840006238A (ko) 1984-11-22
ES8603421A1 (es) 1985-12-16
KR900004694B1 (ko) 1990-07-02
ES526026A0 (es) 1985-12-16
NO833529L (no) 1984-04-02
FI833369A0 (fi) 1983-09-21
EP0105458A2 (en) 1984-04-18
ZA837069B (en) 1984-05-30
CA1246573A (en) 1988-12-13
US4564621A (en) 1986-01-14
FI833369A (fi) 1984-03-31
JPS5980664A (ja) 1984-05-10
NO162017B (no) 1989-07-17
DK421183D0 (da) 1983-09-15
EP0105458B1 (en) 1989-11-23

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