NO162017C - Analogifremgangsmaate for fremstilling av terapeutisk aktive alfa-aryl-alfa-pyridylalkansyrederivater. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive alfa-aryl-alfa-pyridylalkansyrederivater.

Info

Publication number
NO162017C
NO162017C NO833529A NO833529A NO162017C NO 162017 C NO162017 C NO 162017C NO 833529 A NO833529 A NO 833529A NO 833529 A NO833529 A NO 833529A NO 162017 C NO162017 C NO 162017C
Authority
NO
Norway
Prior art keywords
sup
lower alkyl
alfa
aryl
hydrogen
Prior art date
Application number
NO833529A
Other languages
English (en)
Other versions
NO833529L (no
NO162017B (no
Inventor
Ikuo Ueda
Masanobu Nagano
Atsushi Akahane
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of NO833529L publication Critical patent/NO833529L/no
Publication of NO162017B publication Critical patent/NO162017B/no
Publication of NO162017C publication Critical patent/NO162017C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57Nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56Amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
NO833529A 1982-09-30 1983-09-29 Analogifremgangsmaate for fremstilling av terapeutisk aktive alfa-aryl-alfa-pyridylalkansyrederivater. NO162017C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57172936A JPS5980664A (ja) 1982-09-30 1982-09-30 α−アリ−ル−α−ピリジル脂肪酸誘導体およびその製法

Publications (3)

Publication Number Publication Date
NO833529L NO833529L (no) 1984-04-02
NO162017B NO162017B (no) 1989-07-17
NO162017C true NO162017C (no) 1989-10-25

Family

ID=15951089

Family Applications (1)

Application Number Title Priority Date Filing Date
NO833529A NO162017C (no) 1982-09-30 1983-09-29 Analogifremgangsmaate for fremstilling av terapeutisk aktive alfa-aryl-alfa-pyridylalkansyrederivater.

Country Status (14)

Country Link
US (1) US4564621A (no)
EP (1) EP0105458B1 (no)
JP (1) JPS5980664A (no)
KR (1) KR900004694B1 (no)
AT (1) ATE48130T1 (no)
CA (1) CA1246573A (no)
DE (1) DE3380876D1 (no)
DK (1) DK157854C (no)
ES (1) ES526026A0 (no)
FI (1) FI80878C (no)
GR (1) GR78525B (no)
HU (1) HU193046B (no)
NO (1) NO162017C (no)
ZA (1) ZA837069B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60112762A (ja) * 1983-11-21 1985-06-19 Fujisawa Pharmaceut Co Ltd α−アリ−ル−α−ピリジル脂肪酸誘導体およびその製法
US4810703A (en) * 1984-10-19 1989-03-07 A. H. Robins Company, Incorporated 1-((aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-alpha, alpha-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles
US4783537A (en) * 1985-11-13 1988-11-08 Pennwalt Corporation α-(aminoalkyl)-arylacetic acid derivatives
US5202331A (en) * 1990-04-18 1993-04-13 Fujisawa Pharmaceutical Co., Ltd. Therapeutic agent for dysuria comprising alpha-phenyl-alpha-pyridylalkanoic acid derivatives
ATE349451T1 (de) * 2001-01-24 2007-01-15 Cadila Healthcare Ltd Verfahren zur herstellung von clopidogrel
AU2011245499B2 (en) 2010-04-30 2014-09-25 Merck Sharp & Dohme Corp. Novel beta 3 adrenergic receptor agonists

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA501690A (en) * 1954-04-20 Schering Corporation Pyridyl substituted alkanes
NL70757C (no) * 1947-10-13
GB771814A (en) * 1954-06-04 1957-04-03 Pharmacia Ab New butyryl amides and processes for their manufacture
US2991289A (en) * 1958-02-05 1961-07-04 Merck Ag E Derivatives of 1-aminopropane
GB915804A (en) * 1958-04-12 1963-01-16 Degussa Process for the production of basically substituted carboxylic acid amides
FR2485M (fr) * 1961-05-17 1964-04-27 Searle & Co Nouveaux régulateurs cardiaques.
US3225054A (en) * 1962-07-03 1965-12-21 Searle & Co 4-dipropylamino-2-aryl-2-pyridylalkanamides
JPS5248862B2 (no) * 1971-08-16 1977-12-13

Also Published As

Publication number Publication date
ES8603421A1 (es) 1985-12-16
EP0105458A3 (en) 1985-11-27
CA1246573A (en) 1988-12-13
JPS5980664A (ja) 1984-05-10
EP0105458A2 (en) 1984-04-18
NO833529L (no) 1984-04-02
FI80878B (fi) 1990-04-30
KR900004694B1 (ko) 1990-07-02
FI80878C (fi) 1990-08-10
KR840006238A (ko) 1984-11-22
ES526026A0 (es) 1985-12-16
DK157854B (da) 1990-02-26
JPS635025B2 (no) 1988-02-01
DK421183D0 (da) 1983-09-15
DK421183A (da) 1984-03-31
US4564621A (en) 1986-01-14
DE3380876D1 (en) 1989-12-28
EP0105458B1 (en) 1989-11-23
HU193046B (en) 1987-08-28
FI833369A (fi) 1984-03-31
DK157854C (da) 1990-07-23
GR78525B (no) 1984-09-27
FI833369A0 (fi) 1983-09-21
ATE48130T1 (de) 1989-12-15
NO162017B (no) 1989-07-17
ZA837069B (en) 1984-05-30

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