KR880003985A - 블록 공중합체 및 시약운반시스템으로 이것의 사용 - Google Patents

블록 공중합체 및 시약운반시스템으로 이것의 사용 Download PDF

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Publication number
KR880003985A
KR880003985A KR870009842A KR870009842A KR880003985A KR 880003985 A KR880003985 A KR 880003985A KR 870009842 A KR870009842 A KR 870009842A KR 870009842 A KR870009842 A KR 870009842A KR 880003985 A KR880003985 A KR 880003985A
Authority
KR
South Korea
Prior art keywords
block
copolymer
oxide
delivery system
cyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR870009842A
Other languages
English (en)
Korean (ko)
Inventor
제임즈 케이시 도널드
로우재티 루이스
켄드릭 재릿트 피이터
Original Assignee
원본미기재
아메리칸 사이아나밋드 캄파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/903,801 external-priority patent/US4882168A/en
Priority claimed from US06/903,797 external-priority patent/US4716203A/en
Application filed by 원본미기재, 아메리칸 사이아나밋드 캄파니 filed Critical 원본미기재
Publication of KR880003985A publication Critical patent/KR880003985A/ko
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/64Polyesters containing both carboxylic ester groups and carbonate groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
KR870009842A 1986-09-05 1987-09-04 블록 공중합체 및 시약운반시스템으로 이것의 사용 Ceased KR880003985A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/903,801 US4882168A (en) 1986-09-05 1986-09-05 Polyesters containing alkylene oxide blocks as drug delivery systems
US06/903,797 US4716203A (en) 1986-09-05 1986-09-05 Diblock and triblock copolymers
US903801 1986-09-05
US903797 1986-09-05

Publications (1)

Publication Number Publication Date
KR880003985A true KR880003985A (ko) 1988-05-31

Family

ID=27129378

Family Applications (1)

Application Number Title Priority Date Filing Date
KR870009842A Ceased KR880003985A (ko) 1986-09-05 1987-09-04 블록 공중합체 및 시약운반시스템으로 이것의 사용

Country Status (13)

Country Link
EP (1) EP0258780B1 (enExample)
KR (1) KR880003985A (enExample)
AU (1) AU605172B2 (enExample)
BR (1) BR8704648A (enExample)
CA (1) CA1283988C (enExample)
DE (1) DE3786309T2 (enExample)
DK (1) DK462287A (enExample)
ES (1) ES2058081T3 (enExample)
FI (1) FI873840A7 (enExample)
GR (1) GR3008526T3 (enExample)
HU (1) HU205711B (enExample)
IL (1) IL83764A (enExample)
NZ (1) NZ221647A (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL9401703A (nl) * 1994-10-14 1996-05-01 Rijksuniversiteit Kauwgom.
US5665428A (en) * 1995-10-25 1997-09-09 Macromed, Inc. Preparation of peptide containing biodegradable microspheres by melt process
US5702717A (en) * 1995-10-25 1997-12-30 Macromed, Inc. Thermosensitive biodegradable polymers based on poly(ether-ester)block copolymers
DE19726412A1 (de) * 1997-06-21 1998-12-24 Merck Patent Gmbh Implantatmaterial mit einer Träger-Wirkstoff-Kombination
ATE290037T1 (de) * 1997-10-03 2005-03-15 Macromed Inc Biologisch abbaubare triblock-poly(lactide-co- glycolide)-polyethylenglycol-copolymere mit umgekehrter thermischer gelierung
US6117949A (en) * 1998-10-01 2000-09-12 Macromed, Inc. Biodegradable low molecular weight triblock poly (lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
US6004573A (en) * 1997-10-03 1999-12-21 Macromed, Inc. Biodegradable low molecular weight triblock poly(lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
US6201072B1 (en) 1997-10-03 2001-03-13 Macromed, Inc. Biodegradable low molecular weight triblock poly(lactide-co- glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
US7662409B2 (en) 1998-09-25 2010-02-16 Gel-Del Technologies, Inc. Protein matrix materials, devices and methods of making and using thereof
US7018645B1 (en) 2000-04-27 2006-03-28 Macromed, Inc. Mixtures of various triblock polyester polyethylene glycol copolymers having improved gel properties
WO2002076227A1 (en) 2001-03-23 2002-10-03 Gumlink A/S Coated degradable chewing gum with improved shelf life and process for preparing same
US20040180111A1 (en) * 2001-03-23 2004-09-16 Lone Andersen Degradable resin substitute for chewing gum
JP2004535431A (ja) 2001-06-22 2004-11-25 サザン バイオシステムズ, インコーポレイテッド ゼロ次長期放出同軸インプラント
EP1476489B8 (en) * 2002-02-15 2008-10-08 Nektar Therapeutics Al, Corporation Hydrolytically degradable alkylene oxide based polymers
WO2003092468A2 (en) 2002-04-29 2003-11-13 Gel-Del Technologies, Inc. Biomatrix structural containment and fixation systems and methods of use thereof
CN1290893C (zh) * 2002-05-03 2006-12-20 詹森药业有限公司 聚合物微乳状液
US7649023B2 (en) 2002-06-11 2010-01-19 Novartis Ag Biodegradable block copolymeric compositions for drug delivery
BR122012021252B8 (pt) 2002-09-06 2021-05-25 Cerulean Pharma Inc polímeros à base de ciclodextrina para o fornecimento de agentes terapêuticos ligados a eles por covalência
WO2004028266A1 (en) 2002-09-24 2004-04-08 Gumlink A/S Biodegradable chewing gum comprising at least one high molecular weight biodegradable polymer
US8293295B2 (en) 2002-09-24 2012-10-23 Gumlink A/S Chewing gum comprising at least two different biodegradable polymers
ATE405170T1 (de) 2003-05-06 2008-09-15 Gumlink As Methode zur herstellung von kaugummigranulat und komprimierten kaugummiprodukten, sowie ein kaugummigranuliersystem
DK1474995T3 (da) 2003-05-06 2013-02-18 Gumlink As Fremgangsmåde til fremstilling af tyggegummigranulater, et gummisammensætningsekstruder- og granuleringssystem og et tyggegummiprodukt
US8465537B2 (en) 2003-06-17 2013-06-18 Gel-Del Technologies, Inc. Encapsulated or coated stent systems
EP1660013A4 (en) 2003-08-26 2011-07-20 Gel Del Technologies Inc BIOMATERIAL AND PROTEIN BIOCOACERVATES, METHODS OF MAKING AND USING THEM
CA2548822C (en) 2003-12-08 2015-08-11 Gel-Del Technologies, Inc. Mucoadhesive drug delivery devices and methods of making and using thereof
JP2010516625A (ja) 2007-01-24 2010-05-20 インサート セラピューティクス, インコーポレイテッド 制御された薬物送達のためのテザー基を有するポリマー−薬物コンジュゲート
AU2008345047A1 (en) 2007-12-26 2009-07-09 Gel-Del Technologies, Inc. Biocompatible protein particles, particle devices and methods thereof
WO2010057177A2 (en) 2008-11-17 2010-05-20 Gel-Del Technologies, Inc. Protein biomaterial and biocoacervate vessel graft systems and methods of making and using thereof
CA2774015A1 (en) 2009-09-15 2011-03-24 Cerulean Pharma Inc. A cdp-camptothecin conjugate, particle or composition and uses thereof
CN103037903A (zh) 2010-05-18 2013-04-10 天蓝制药公司 用于治疗自身免疫性疾病或其它疾病的组合物和方法
WO2014055493A1 (en) 2012-10-02 2014-04-10 Cerulean Pharma Inc. Methods and systems for polymer precipitation and generation of particles
US20230285576A1 (en) 2020-08-05 2023-09-14 Ellipses Pharma Ltd Treatment of cancer using a cyclodextrin-containing polymer-topoisomerase inhibitor conjugate and a parp inhibitor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3736646A (en) * 1971-10-18 1973-06-05 American Cyanamid Co Method of attaching surgical needles to multifilament polyglycolic acid absorbable sutures
US4047533A (en) * 1976-09-20 1977-09-13 American Cyanamid Company Absorbable surgical sutures coated with polyoxyethylene-polyoxypropylene copolymer lubricant
US4429080A (en) * 1982-07-01 1984-01-31 American Cyanamid Company Synthetic copolymer surgical articles and method of manufacturing the same
US4438253A (en) * 1982-11-12 1984-03-20 American Cyanamid Company Poly(glycolic acid)/poly(alkylene glycol) block copolymers and method of manufacturing the same
US4452973A (en) * 1982-11-12 1984-06-05 American Cyanamid Company Poly(glycolic acid)/poly(oxyethylene) triblock copolymers and method of manufacturing the same

Also Published As

Publication number Publication date
ES2058081T3 (es) 1994-11-01
FI873840L (fi) 1988-03-06
NZ221647A (en) 1990-09-26
HUT52945A (en) 1990-09-28
BR8704648A (pt) 1988-04-26
FI873840A7 (fi) 1988-03-06
FI873840A0 (fi) 1987-09-04
IL83764A0 (en) 1988-02-29
DE3786309D1 (de) 1993-07-29
CA1283988C (en) 1991-05-07
AU7797087A (en) 1988-03-10
EP0258780B1 (en) 1993-06-23
DK462287D0 (da) 1987-09-04
DK462287A (da) 1988-03-06
AU605172B2 (en) 1991-01-10
IL83764A (en) 1991-05-12
GR3008526T3 (enExample) 1993-10-29
DE3786309T2 (de) 1994-02-10
HU205711B (en) 1992-06-29
EP0258780A2 (en) 1988-03-09
EP0258780A3 (en) 1988-05-18

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