KR870007900A - 태트라 사이클릭 퀴나졸리논 및 그의 제조방법 - Google Patents

태트라 사이클릭 퀴나졸리논 및 그의 제조방법 Download PDF

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Publication number
KR870007900A
KR870007900A KR870001150A KR870001150A KR870007900A KR 870007900 A KR870007900 A KR 870007900A KR 870001150 A KR870001150 A KR 870001150A KR 870001150 A KR870001150 A KR 870001150A KR 870007900 A KR870007900 A KR 870007900A
Authority
KR
South Korea
Prior art keywords
compound
pharmaceutically acceptable
acid addition
addition salt
acceptable acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR870001150A
Other languages
English (en)
Korean (ko)
Inventor
에듀아드 하트만 괴츠
조세프 호울리한 윌리암
칼 안드레아스 가이거 루돌프
Original Assignee
원본미기재
산도즈 파마슈티갈스 코포레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 원본미기재, 산도즈 파마슈티갈스 코포레이션 filed Critical 원본미기재
Publication of KR870007900A publication Critical patent/KR870007900A/ko
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
KR870001150A 1986-02-13 1987-02-12 태트라 사이클릭 퀴나졸리논 및 그의 제조방법 Withdrawn KR870007900A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US829594 1986-02-13
US06/829,594 US4760065A (en) 1986-02-13 1986-02-13 Trifluoromethyl substituted tetracyclic quinazolin-ones having tranquilizing activity

Publications (1)

Publication Number Publication Date
KR870007900A true KR870007900A (ko) 1987-09-22

Family

ID=25254954

Family Applications (1)

Application Number Title Priority Date Filing Date
KR870001150A Withdrawn KR870007900A (ko) 1986-02-13 1987-02-12 태트라 사이클릭 퀴나졸리논 및 그의 제조방법

Country Status (22)

Country Link
US (1) US4760065A (enExample)
JP (1) JPS62223183A (enExample)
KR (1) KR870007900A (enExample)
AT (1) AT390062B (enExample)
AU (1) AU597936B2 (enExample)
BE (1) BE1002099A3 (enExample)
CH (1) CH671019A5 (enExample)
DE (1) DE3702943A1 (enExample)
DK (1) DK69787A (enExample)
ES (1) ES2004215A6 (enExample)
FI (1) FI870510L (enExample)
FR (1) FR2601013A1 (enExample)
GB (1) GB2186574B (enExample)
GR (1) GR870232B (enExample)
HU (1) HU198932B (enExample)
IL (1) IL81536A0 (enExample)
IT (1) IT1216790B (enExample)
LU (1) LU86769A1 (enExample)
NL (1) NL8700233A (enExample)
NZ (1) NZ219242A (enExample)
SE (1) SE8700566L (enExample)
ZA (1) ZA871077B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2113115A1 (en) * 1991-07-29 1993-02-18 Vlad E. Gregor Quinazoline derivatives as acetylcholinesterase inhibitors
US6133002A (en) 1997-09-25 2000-10-17 Dsm N.V. Process for preparing optically active 2-amino-ω-oxoalkanoic acid derivatives
EP2447239A1 (en) * 2010-10-29 2012-05-02 Saltigo GmbH Copper-catalysed process for the production of substituted or unsubstituted trifluormethylated aryl and heteroaryl compounds

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3280117A (en) * 1964-04-20 1966-10-18 Sandoz Ag Tricyclic quinazolinones
US3631046A (en) * 1969-05-28 1971-12-28 Sandoz Ag Tetracyclic quinazolin-ones
US3598823A (en) * 1969-05-28 1971-08-10 Sandoz Ag Tricyclic quinazolinones
US3772230A (en) * 1969-05-28 1973-11-13 Sandoz Ag Polyhydro-imidazo(1,5-a)pyrimidine-3(2h)-thione and pyrido(1,2-c)pyrimidine-1-thione
US4000275A (en) * 1969-11-24 1976-12-28 Eli Lilly And Company Immunosuppressants
BE760013A (fr) * 1969-12-18 1971-06-08 Smith Kline French Lab Imidazo et pyrimido -(2,1-b)quinazolines, leurs procedes de preparationet compositions pharmaceutiques en contenant
US3868372A (en) * 1971-07-09 1975-02-25 Sandoz Ag Organomercapto-substituted polyhydro imidazo{8 1,5-a{9 pyridenes and pyride{8 1,2-c{9 pyrimidines
US3963720A (en) * 1972-10-27 1976-06-15 Sandoz, Inc. Tetracyclic imidazo [2,1-b] quinazolinone derivatives
PH19788A (en) * 1981-09-16 1986-07-02 Sandoz Ag 1-substituted tricyclic quinazolinones,pharmaceutical composition containing same and method of use thereof
PH17745A (en) * 1981-09-16 1984-11-27 Sandoz Ag Trifluoromethyl substituted tricyclic quinazolinones
FR2512674B1 (fr) * 1981-09-16 1986-01-10 Sandoz Sa Nouveaux derives tricycliques de la quinazolinone, leur preparation et medicaments contenant ces derives
US4452787A (en) * 1981-09-16 1984-06-05 Sandoz, Inc. 1-Substituted tricyclic quinazolinones having biological activity as tranquilizers

Also Published As

Publication number Publication date
US4760065A (en) 1988-07-26
CH671019A5 (enExample) 1989-07-31
NL8700233A (nl) 1987-09-01
SE8700566D0 (sv) 1987-02-12
GB2186574A (en) 1987-08-19
DK69787D0 (da) 1987-02-11
IT8747634A0 (it) 1987-02-12
JPS62223183A (ja) 1987-10-01
HU198932B (en) 1989-12-28
FI870510A7 (fi) 1987-08-14
GB8702938D0 (en) 1987-03-18
IL81536A0 (en) 1987-09-16
ES2004215A6 (es) 1988-12-16
ATA29687A (de) 1989-08-15
AT390062B (de) 1990-03-12
LU86769A1 (fr) 1987-09-15
AU597936B2 (en) 1990-06-14
HUT43607A (en) 1987-11-30
GB2186574B (en) 1990-03-28
GR870232B (en) 1987-06-12
DK69787A (da) 1987-08-14
FI870510L (fi) 1987-08-14
ZA871077B (en) 1988-09-28
IT1216790B (it) 1990-03-14
FR2601013A1 (fr) 1988-01-08
NZ219242A (en) 1990-04-26
DE3702943A1 (de) 1987-08-20
BE1002099A3 (fr) 1990-07-03
FI870510A0 (fi) 1987-02-09
SE8700566L (sv) 1987-08-14
AU6869487A (en) 1987-08-20

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Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19870212

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid