ATA29687A - Verfahren zur herstellung von neuen trifluormethyl substituierten tetracyclischen chinazolinonen und ihrer saeureadditionssalze - Google Patents
Verfahren zur herstellung von neuen trifluormethyl substituierten tetracyclischen chinazolinonen und ihrer saeureadditionssalzeInfo
- Publication number
- ATA29687A ATA29687A AT0029687A AT29687A ATA29687A AT A29687 A ATA29687 A AT A29687A AT 0029687 A AT0029687 A AT 0029687A AT 29687 A AT29687 A AT 29687A AT A29687 A ATA29687 A AT A29687A
- Authority
- AT
- Austria
- Prior art keywords
- chinazolinones
- trifluormethyl
- acid addition
- addition salts
- producing new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/829,594 US4760065A (en) | 1986-02-13 | 1986-02-13 | Trifluoromethyl substituted tetracyclic quinazolin-ones having tranquilizing activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA29687A true ATA29687A (de) | 1989-08-15 |
| AT390062B AT390062B (de) | 1990-03-12 |
Family
ID=25254954
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0029687A AT390062B (de) | 1986-02-13 | 1987-02-12 | Verfahren zur herstellung von neuen trifluormethyl substituierten tetracyclischen chinazolinonen und ihrer saeureadditionssalze |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4760065A (de) |
| JP (1) | JPS62223183A (de) |
| KR (1) | KR870007900A (de) |
| AT (1) | AT390062B (de) |
| AU (1) | AU597936B2 (de) |
| BE (1) | BE1002099A3 (de) |
| CH (1) | CH671019A5 (de) |
| DE (1) | DE3702943A1 (de) |
| DK (1) | DK69787A (de) |
| ES (1) | ES2004215A6 (de) |
| FI (1) | FI870510A (de) |
| FR (1) | FR2601013A1 (de) |
| GB (1) | GB2186574B (de) |
| GR (1) | GR870232B (de) |
| HU (1) | HU198932B (de) |
| IL (1) | IL81536A0 (de) |
| IT (1) | IT1216790B (de) |
| LU (1) | LU86769A1 (de) |
| NL (1) | NL8700233A (de) |
| NZ (1) | NZ219242A (de) |
| SE (1) | SE8700566L (de) |
| ZA (1) | ZA871077B (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ281628B6 (cs) * | 1991-07-29 | 1996-11-13 | Warner-Lambert Company | Deriváty chinazolinu a farmaceutické přípravky na jejich bázi |
| US6133002A (en) | 1997-09-25 | 2000-10-17 | Dsm N.V. | Process for preparing optically active 2-amino-ω-oxoalkanoic acid derivatives |
| EP2447239A1 (de) * | 2010-10-29 | 2012-05-02 | Saltigo GmbH | Kupfer-katalysiertes Verfahren zur Herstellung von substituiertem oder nichtsubstituiertem trifluormethyliertem Aryl und Heteroarylverbindungen |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3280117A (en) * | 1964-04-20 | 1966-10-18 | Sandoz Ag | Tricyclic quinazolinones |
| US3631046A (en) * | 1969-05-28 | 1971-12-28 | Sandoz Ag | Tetracyclic quinazolin-ones |
| US3598823A (en) * | 1969-05-28 | 1971-08-10 | Sandoz Ag | Tricyclic quinazolinones |
| US3772230A (en) * | 1969-05-28 | 1973-11-13 | Sandoz Ag | Polyhydro-imidazo(1,5-a)pyrimidine-3(2h)-thione and pyrido(1,2-c)pyrimidine-1-thione |
| US4000275A (en) * | 1969-11-24 | 1976-12-28 | Eli Lilly And Company | Immunosuppressants |
| BE760013A (fr) * | 1969-12-18 | 1971-06-08 | Smith Kline French Lab | Imidazo et pyrimido -(2,1-b)quinazolines, leurs procedes de preparationet compositions pharmaceutiques en contenant |
| US3868372A (en) * | 1971-07-09 | 1975-02-25 | Sandoz Ag | Organomercapto-substituted polyhydro imidazo{8 1,5-a{9 pyridenes and pyride{8 1,2-c{9 pyrimidines |
| US3963720A (en) * | 1972-10-27 | 1976-06-15 | Sandoz, Inc. | Tetracyclic imidazo [2,1-b] quinazolinone derivatives |
| FR2512674B1 (fr) * | 1981-09-16 | 1986-01-10 | Sandoz Sa | Nouveaux derives tricycliques de la quinazolinone, leur preparation et medicaments contenant ces derives |
| US4452787A (en) * | 1981-09-16 | 1984-06-05 | Sandoz, Inc. | 1-Substituted tricyclic quinazolinones having biological activity as tranquilizers |
| PH19788A (en) * | 1981-09-16 | 1986-07-02 | Sandoz Ag | 1-substituted tricyclic quinazolinones,pharmaceutical composition containing same and method of use thereof |
| PH17745A (en) * | 1981-09-16 | 1984-11-27 | Sandoz Ag | Trifluoromethyl substituted tricyclic quinazolinones |
-
1986
- 1986-02-13 US US06/829,594 patent/US4760065A/en not_active Expired - Fee Related
-
1987
- 1987-01-30 NL NL8700233A patent/NL8700233A/nl not_active Application Discontinuation
- 1987-01-30 HU HU87305A patent/HU198932B/hu not_active IP Right Cessation
- 1987-01-30 CH CH346/87A patent/CH671019A5/de not_active IP Right Cessation
- 1987-01-31 DE DE19873702943 patent/DE3702943A1/de not_active Withdrawn
- 1987-02-09 FR FR8701669A patent/FR2601013A1/fr active Pending
- 1987-02-09 FI FI870510A patent/FI870510A/fi not_active Application Discontinuation
- 1987-02-10 GB GB8702938A patent/GB2186574B/en not_active Expired - Lifetime
- 1987-02-11 DK DK069787A patent/DK69787A/da not_active Application Discontinuation
- 1987-02-11 NZ NZ219242A patent/NZ219242A/en unknown
- 1987-02-11 GR GR870232A patent/GR870232B/el unknown
- 1987-02-11 IL IL81536A patent/IL81536A0/xx unknown
- 1987-02-11 AU AU68694/87A patent/AU597936B2/en not_active Ceased
- 1987-02-11 ES ES8700334A patent/ES2004215A6/es not_active Expired
- 1987-02-12 KR KR870001150A patent/KR870007900A/ko not_active Application Discontinuation
- 1987-02-12 AT AT0029687A patent/AT390062B/de not_active IP Right Cessation
- 1987-02-12 LU LU86769A patent/LU86769A1/fr unknown
- 1987-02-12 JP JP62028370A patent/JPS62223183A/ja active Pending
- 1987-02-12 SE SE8700566A patent/SE8700566L/xx not_active Application Discontinuation
- 1987-02-12 IT IT8747634A patent/IT1216790B/it active
- 1987-02-12 BE BE8700112A patent/BE1002099A3/fr active
- 1987-02-13 ZA ZA871077A patent/ZA871077B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK69787D0 (da) | 1987-02-11 |
| CH671019A5 (de) | 1989-07-31 |
| US4760065A (en) | 1988-07-26 |
| AU597936B2 (en) | 1990-06-14 |
| ES2004215A6 (es) | 1988-12-16 |
| AU6869487A (en) | 1987-08-20 |
| SE8700566L (sv) | 1987-08-14 |
| SE8700566D0 (sv) | 1987-02-12 |
| IT1216790B (it) | 1990-03-14 |
| HUT43607A (en) | 1987-11-30 |
| GB2186574B (en) | 1990-03-28 |
| IT8747634A0 (it) | 1987-02-12 |
| AT390062B (de) | 1990-03-12 |
| LU86769A1 (fr) | 1987-09-15 |
| IL81536A0 (en) | 1987-09-16 |
| BE1002099A3 (fr) | 1990-07-03 |
| FR2601013A1 (fr) | 1988-01-08 |
| KR870007900A (ko) | 1987-09-22 |
| DK69787A (da) | 1987-08-14 |
| GR870232B (en) | 1987-06-12 |
| GB2186574A (en) | 1987-08-19 |
| JPS62223183A (ja) | 1987-10-01 |
| HU198932B (en) | 1989-12-28 |
| FI870510A (fi) | 1987-08-14 |
| GB8702938D0 (en) | 1987-03-18 |
| FI870510A0 (fi) | 1987-02-09 |
| ZA871077B (en) | 1988-09-28 |
| DE3702943A1 (de) | 1987-08-20 |
| NL8700233A (nl) | 1987-09-01 |
| NZ219242A (en) | 1990-04-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| ELJ | Ceased due to non-payment of the annual fee | ||
| REN | Ceased due to non-payment of the annual fee |