KR870001986B1 - 세팔로스포린 유도체의 제조방법 - Google Patents

세팔로스포린 유도체의 제조방법 Download PDF

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Publication number
KR870001986B1
KR870001986B1 KR1019830000871A KR830000871A KR870001986B1 KR 870001986 B1 KR870001986 B1 KR 870001986B1 KR 1019830000871 A KR1019830000871 A KR 1019830000871A KR 830000871 A KR830000871 A KR 830000871A KR 870001986 B1 KR870001986 B1 KR 870001986B1
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KR
South Korea
Prior art keywords
methyl
compound
formula
group
carboxylate
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Expired
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KR1019830000871A
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English (en)
Korean (ko)
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KR840004118A (ko
Inventor
아부라키 심페이
카마치 하지메
나리타 유키오
준오쿠무라
유키나이토 타카
Original Assignee
브리스톨-마이어즈 리써어치 인스티튜트 리미티드
지우리오 비타
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Publication date
Priority claimed from US06/354,851 external-priority patent/US4406899A/en
Application filed by 브리스톨-마이어즈 리써어치 인스티튜트 리미티드, 지우리오 비타 filed Critical 브리스톨-마이어즈 리써어치 인스티튜트 리미티드
Publication of KR840004118A publication Critical patent/KR840004118A/ko
Application granted granted Critical
Publication of KR870001986B1 publication Critical patent/KR870001986B1/ko
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019830000871A 1982-03-04 1983-03-04 세팔로스포린 유도체의 제조방법 Expired KR870001986B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US354,851 1982-03-04
US354851 1982-03-04
US06/354,851 US4406899A (en) 1982-03-04 1982-03-04 Cephalosporins
US35753482A 1982-03-12 1982-03-12
US357,534 1982-03-12
US357534 1982-03-12

Publications (2)

Publication Number Publication Date
KR840004118A KR840004118A (ko) 1984-10-06
KR870001986B1 true KR870001986B1 (ko) 1987-10-24

Family

ID=26998584

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830000871A Expired KR870001986B1 (ko) 1982-03-04 1983-03-04 세팔로스포린 유도체의 제조방법

Country Status (29)

Country Link
KR (1) KR870001986B1 (enrdf_load_stackoverflow)
AT (2) AT382155B (enrdf_load_stackoverflow)
AU (1) AU562776B2 (enrdf_load_stackoverflow)
BE (1) BE896086A (enrdf_load_stackoverflow)
CA (1) CA1213882A (enrdf_load_stackoverflow)
CH (1) CH654313A5 (enrdf_load_stackoverflow)
CS (1) CS249512B2 (enrdf_load_stackoverflow)
DD (1) DD210280A5 (enrdf_load_stackoverflow)
DE (1) DE3307550A1 (enrdf_load_stackoverflow)
DK (1) DK156900C (enrdf_load_stackoverflow)
EG (1) EG15934A (enrdf_load_stackoverflow)
ES (2) ES520224A0 (enrdf_load_stackoverflow)
FI (1) FI74973C (enrdf_load_stackoverflow)
FR (1) FR2522659B1 (enrdf_load_stackoverflow)
GB (1) GB2116180B (enrdf_load_stackoverflow)
GR (1) GR77916B (enrdf_load_stackoverflow)
HU (1) HU193158B (enrdf_load_stackoverflow)
IE (1) IE56647B1 (enrdf_load_stackoverflow)
IL (1) IL68011A0 (enrdf_load_stackoverflow)
IT (1) IT1170307B (enrdf_load_stackoverflow)
LU (1) LU84674A1 (enrdf_load_stackoverflow)
MY (1) MY8700943A (enrdf_load_stackoverflow)
NL (2) NL193284C (enrdf_load_stackoverflow)
NZ (1) NZ203312A (enrdf_load_stackoverflow)
PH (1) PH18002A (enrdf_load_stackoverflow)
PT (1) PT76330B (enrdf_load_stackoverflow)
SE (1) SE453091B (enrdf_load_stackoverflow)
SU (1) SU1250173A3 (enrdf_load_stackoverflow)
YU (2) YU43822B (enrdf_load_stackoverflow)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3409431A1 (de) * 1983-10-08 1985-04-18 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3404906A1 (de) * 1984-02-11 1985-08-14 Bayer Ag, 5090 Leverkusen 1-oxadethiacephalosporinderivate sowie verfahren zu ihrer herstellung
DE3419013A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Neue cephalosporine und verfahren zu ihrer herstellung
GB8424692D0 (en) * 1984-10-01 1984-11-07 Glaxo Group Ltd Chemical compounds
US4698336A (en) * 1985-01-30 1987-10-06 Eisai Co., Ltd. 3-(pyrrolidinio)methyl-3-cephem derivatives
FR2585705B1 (fr) * 1985-08-05 1989-01-13 Bristol Myers Co Sels de cephalosporine et compositions injectables
US4910301A (en) * 1985-08-05 1990-03-20 Bristol-Myers Company Cefepime cephalosporin salts
US4808617A (en) * 1985-12-18 1989-02-28 Bristol-Myers Company Lyophilized or precipitated cephalosporin zwitterion and salt combination
DE3789466T2 (de) * 1986-03-17 1994-07-28 Fujisawa Pharmaceutical Co 3,7-Disubstituierte-3-Cephemverbindungen und Verfahren zu ihrer Herstellung.
CA2011116C (en) * 1989-03-06 1999-11-16 Murray A. Kaplan Lyophilized bmy-28142 dihydrochloride for parenteral use
DK0503453T3 (da) 1991-03-08 2001-07-16 Biochemie Gmbh Fremgangsmåde til fremstilling af cephalosporiner og mellemprodukter i denne fremgangsmåde
MY108872A (en) * 1991-09-10 1996-11-30 Bristol Myers Squibb Co Preparation of a cephalosporin antibiotic using the syn-isomer of a thiazolyl intermediate.
YU81692A (sh) * 1991-09-10 1995-03-27 Bristol-Myers Co. Postupak za proizvodnju cefalosporinskog antibiotika
US5523400A (en) * 1993-04-16 1996-06-04 Hoffmann-La Roche Inc. Cephalosporin antibiotics
JP4616844B2 (ja) * 2003-12-23 2011-01-19 サンド・ゲーエムベーハー セファロスポリン合成に使用するための中間体の生成プロセス

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2715385A1 (de) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
GB1591439A (en) * 1976-10-01 1981-06-24 Glaxo Operations Ltd 7-syn (oxyimino -acylamido) cephalosporins
AR228726A1 (es) * 1978-05-26 1983-04-15 Glaxo Group Ltd Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato
DK452579A (da) * 1978-10-27 1980-04-28 Glaxo Group Ltd Fremgangsmaade til fremstilling af cephalosporinforbindelser eller salte eller metalbolisk labile estere deraf
US4443444A (en) * 1980-08-11 1984-04-17 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds

Also Published As

Publication number Publication date
EG15934A (en) 1987-10-30
SE453091B (sv) 1988-01-11
NL193284C (nl) 1999-05-06
DE3307550C2 (enrdf_load_stackoverflow) 1988-11-24
ATA228285A (de) 1987-05-15
SU1250173A3 (ru) 1986-08-07
IL68011A0 (en) 1983-06-15
IT8347826A0 (it) 1983-03-01
NZ203312A (en) 1985-12-13
YU44777B (en) 1991-02-28
FR2522659B1 (fr) 1986-10-24
NL193284B (nl) 1999-01-04
GB2116180A (en) 1983-09-21
CH654313A5 (de) 1986-02-14
DK156900C (da) 1990-03-12
GB8305940D0 (en) 1983-04-07
GB2116180B (en) 1985-09-18
IT1170307B (it) 1987-06-03
SE8301178D0 (sv) 1983-03-03
DK86283A (da) 1983-09-05
DD210280A5 (de) 1984-06-06
YU43822B (en) 1989-12-31
AU1130483A (en) 1983-09-08
LU84674A1 (fr) 1983-11-17
NL990039I1 (nl) 2000-01-03
YU149685A (en) 1986-02-28
FI830689L (fi) 1983-09-05
HU193158B (en) 1987-08-28
PH18002A (en) 1985-02-28
AT382155B (de) 1987-01-26
NL8300755A (nl) 1983-10-03
PT76330B (en) 1986-02-04
ES8403919A1 (es) 1984-04-01
CA1213882A (en) 1986-11-12
FI830689A0 (fi) 1983-03-01
SE8301178L (sv) 1983-09-05
CS249512B2 (en) 1987-03-12
ES526397A0 (es) 1985-09-16
ES8507557A1 (es) 1985-09-16
IE56647B1 (en) 1991-10-23
KR840004118A (ko) 1984-10-06
BE896086A (fr) 1983-09-05
DK86283D0 (da) 1983-02-24
IE830455L (en) 1983-09-04
ES520224A0 (es) 1984-04-01
FR2522659A1 (fr) 1983-09-09
GR77916B (enrdf_load_stackoverflow) 1984-09-25
MY8700943A (en) 1987-12-31
YU52383A (en) 1986-02-28
ATA76183A (de) 1986-06-15
DK156900B (da) 1989-10-16
FI74973B (fi) 1987-12-31
DE3307550A1 (de) 1983-09-15
NL990039I2 (nl) 2000-04-03
AT384612B (de) 1987-12-10
PT76330A (en) 1983-04-01
FI74973C (fi) 1988-04-11
AU562776B2 (en) 1987-06-18

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