KR860001083A - 신규의 모르포리놀의 제법 - Google Patents

신규의 모르포리놀의 제법 Download PDF

Info

Publication number
KR860001083A
KR860001083A KR1019850004786A KR850004786A KR860001083A KR 860001083 A KR860001083 A KR 860001083A KR 1019850004786 A KR1019850004786 A KR 1019850004786A KR 850004786 A KR850004786 A KR 850004786A KR 860001083 A KR860001083 A KR 860001083A
Authority
KR
South Korea
Prior art keywords
hydrogen
morpholinol
process according
resulting
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1019850004786A
Other languages
English (en)
Korean (ko)
Inventor
보만샤우 메타 나리만 (외 1)
Original Assignee
미첼 피터 젝슨
더 웰컴 파운데이숀 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 미첼 피터 젝슨, 더 웰컴 파운데이숀 리미티드 filed Critical 미첼 피터 젝슨
Publication of KR860001083A publication Critical patent/KR860001083A/ko
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
KR1019850004786A 1984-07-05 1985-07-04 신규의 모르포리놀의 제법 Withdrawn KR860001083A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB84-17170 1984-07-05
GB848417170A GB8417170D0 (en) 1984-07-05 1984-07-05 Heterocyclic pharmaceutical compounds

Publications (1)

Publication Number Publication Date
KR860001083A true KR860001083A (ko) 1986-02-22

Family

ID=10563453

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019850004786A Withdrawn KR860001083A (ko) 1984-07-05 1985-07-04 신규의 모르포리놀의 제법

Country Status (12)

Country Link
EP (1) EP0170430A1 (enExample)
JP (1) JPS6124578A (enExample)
KR (1) KR860001083A (enExample)
AU (1) AU4459585A (enExample)
DK (1) DK307385A (enExample)
ES (1) ES8609286A1 (enExample)
FI (1) FI852657A7 (enExample)
GB (1) GB8417170D0 (enExample)
GR (1) GR851645B (enExample)
HU (1) HUT39437A (enExample)
IL (1) IL75720A0 (enExample)
ZA (1) ZA855072B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8924528D0 (en) * 1989-10-31 1989-12-20 Wellcome Found Heterocyclic pharmaceutical compounds,preparation and use
GB9108629D0 (en) * 1991-04-23 1991-06-12 Wellcome Found Heterocyclic pharmaceutical compounds,preparation and use
US7098206B2 (en) 1998-01-21 2006-08-29 Smithkline Beecham Corporation Pharmaceutically active morpholinol
BR9907203A (pt) 1998-01-21 2000-10-17 Glaxo Group Ltd "composto, composições farmacêuticas, uso de um composto, e, processo de tratametno de depressão, distúrbio de hiperatividade por deficiência de atenção (adhd), obesidade, enxaqueca, dor, disfunção sexual, doença de parkinson, doença de alzeheimer, ou vìcio de cocaìna ou de produtos contendo nicotina (especialmente tabaco) em um indivìduo animal ou humano. "
US6998400B2 (en) 1998-01-22 2006-02-14 Smithkline Beecham Corporation Pharmaceutically active morpholinol
US6855820B2 (en) 1999-01-20 2005-02-15 Smithkline Beecham Corporation Pharmaceutically active morpholinol
US6734213B2 (en) 1999-01-20 2004-05-11 Smithkline Beecham Corporation Pharmaceutically active morpholinol
US7241805B2 (en) 2005-06-27 2007-07-10 Biovail Laboratories, Inc. Modified release formulations of a bupropion salt
KR101014438B1 (ko) * 2008-09-26 2011-02-14 동아제약주식회사 탁산 유도체의 제조방법
CA2800220C (en) 2010-05-21 2019-04-30 Research Triangle Institute Phenylmorpholines and analogues thereof
CA2800219C (en) 2010-05-21 2019-03-12 Research Triangle Institute 1 - phenylmorpholine derivatives as hydroxybupropion analogues for treating drug dependence

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3117967A (en) * 1962-04-02 1964-01-14 Smith Kline French Lab 2-biphenylyl-2-hydroxy-morpholinium halides
FR2553413B1 (fr) * 1983-10-17 1986-03-21 Lafon Labor Derives de 4-alkyl-2-hydroxy-3-methyl-2-phenyl-morpholine, procede de preparation et utilisation en therapeutique

Also Published As

Publication number Publication date
JPS6124578A (ja) 1986-02-03
ES8609286A1 (es) 1986-07-16
GB8417170D0 (en) 1984-08-08
EP0170430A1 (en) 1986-02-05
DK307385A (da) 1986-01-06
ES544862A0 (es) 1986-07-16
FI852657L (fi) 1986-01-06
HUT39437A (en) 1986-09-29
AU4459585A (en) 1986-01-09
FI852657A7 (fi) 1986-01-06
FI852657A0 (fi) 1985-07-04
DK307385D0 (da) 1985-07-04
GR851645B (enExample) 1985-11-26
IL75720A0 (en) 1985-11-29
ZA855072B (en) 1987-02-25

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Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19850704

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid