KR860001813A - 트리사이클릭 퀴놀린 유도체의 제조방법 - Google Patents
트리사이클릭 퀴놀린 유도체의 제조방법 Download PDFInfo
- Publication number
- KR860001813A KR860001813A KR1019850005555A KR850005555A KR860001813A KR 860001813 A KR860001813 A KR 860001813A KR 1019850005555 A KR1019850005555 A KR 1019850005555A KR 850005555 A KR850005555 A KR 850005555A KR 860001813 A KR860001813 A KR 860001813A
- Authority
- KR
- South Korea
- Prior art keywords
- quinoline derivative
- general formula
- alkyl
- hydrogen
- tricyclic quinoline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (3)
- 하기 일반식(Ⅱ)의 락탐을 환원시킴을 특징으로 하여 하기 일반식(Ⅰ)의 트리사이클릭 퀴놀린 유도체 또는 약학적으로 허용되는 이의 염을 제조하는 방법.상기식에서(여기서, R1및 R2는 독립적으로 수소 또는 C1~3알킬이다)이고, R은 수소, C1~3직쇄 알킬 또는 알릴이고, 일반식(Ⅱ)에서, 두 비-방향족 환의 환-융합은 트란스이다.
- 제1항에 있어서,R이 수소 또는 C1~3직쇄 알킬인 제조방법.
- 제1 또는 제2항에 있어서, 환원을 수소화 리튬 알루미늄으로 수행하는 제조방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/637,354 US4537965A (en) | 1984-08-03 | 1984-08-03 | Method of preparing 4aR,8aR-5-permissibly substituted-6-oxo-octahydro-1H(and 2H)-pyrazolo[3,4-g]quinolines, useful as intermediates |
US637354 | 1984-08-03 | ||
US637665 | 1984-08-03 | ||
US06/637,665 US4537964A (en) | 1984-08-03 | 1984-08-03 | Method of preparing permissibly-substituted 1H(and 2H)pyrazolo[3,4-g]quinolines; pyrimido[4,5,g]quinolines; thiazolo[4,5,g]quinolines and intermediates therefore |
US637.354 | 1984-08-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR860001813A true KR860001813A (ko) | 1986-03-22 |
KR870000623B1 KR870000623B1 (ko) | 1987-03-26 |
Family
ID=27092807
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019850005555A KR870000623B1 (ko) | 1984-08-03 | 1985-08-01 | 트리사이클릭 퀴놀린 유도체의 제조방법 |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0171277A3 (ko) |
KR (1) | KR870000623B1 (ko) |
AR (1) | AR242033A1 (ko) |
AU (1) | AU579172B2 (ko) |
DK (1) | DK349385A (ko) |
EG (1) | EG17490A (ko) |
ES (1) | ES8604157A1 (ko) |
FI (1) | FI852975L (ko) |
GR (1) | GR851893B (ko) |
HU (1) | HUT40656A (ko) |
IL (1) | IL75992A0 (ko) |
NZ (1) | NZ212947A (ko) |
PT (1) | PT80898B (ko) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI78091C (fi) * | 1983-09-26 | 1989-06-12 | Lilly Co Eli | Analogifoerfarande foer framstaellning av saosom dopaminoagonister anvaendbara pyrimido/4,5-g/kinolinderivat. |
PH22541A (en) * | 1984-08-02 | 1988-10-17 | Lilly Co Eli | Octahydro-oxazolo(4,5-g)quinolines |
US4762843A (en) * | 1986-09-15 | 1988-08-09 | Warner-Lambert Company | Hetero [f] fused carbocyclic pyridines as dopaminergic agents |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4198415A (en) * | 1979-01-22 | 1980-04-15 | Eli Lilly And Company | Prolactin inhibiting octahydro pyrazolo[3,4-g]quinolines |
ES524452A0 (es) * | 1982-11-03 | 1985-04-16 | Lilly Co Eli | Un procedimiento para la preparacion de derivados de pirazolo-quinolinas. |
ES8501395A1 (es) * | 1982-11-03 | 1984-12-01 | Lilly Co Eli | Un procedimiento para la obtencion de un tautomero de pirazoloquinolinas |
FI78091C (fi) * | 1983-09-26 | 1989-06-12 | Lilly Co Eli | Analogifoerfarande foer framstaellning av saosom dopaminoagonister anvaendbara pyrimido/4,5-g/kinolinderivat. |
US4525584A (en) * | 1984-08-03 | 1985-06-25 | Eli Lilly And Company | 4aR,8aS,9R-5,6-Permissibly substituted-9-hydroxy-octahydro-1H(and 2H) pyrazolo[3,4-g]quinoline |
-
1985
- 1985-08-01 GR GR851893A patent/GR851893B/el unknown
- 1985-08-01 HU HU852955A patent/HUT40656A/hu unknown
- 1985-08-01 EG EG461/85A patent/EG17490A/xx active
- 1985-08-01 KR KR1019850005555A patent/KR870000623B1/ko not_active IP Right Cessation
- 1985-08-01 AR AR85301158A patent/AR242033A1/es active
- 1985-08-01 NZ NZ212947A patent/NZ212947A/xx unknown
- 1985-08-01 PT PT80898A patent/PT80898B/pt not_active IP Right Cessation
- 1985-08-01 DK DK349385A patent/DK349385A/da not_active Application Discontinuation
- 1985-08-01 IL IL75992A patent/IL75992A0/xx not_active IP Right Cessation
- 1985-08-01 FI FI852975A patent/FI852975L/fi not_active Application Discontinuation
- 1985-08-02 AU AU45738/85A patent/AU579172B2/en not_active Ceased
- 1985-08-02 ES ES545860A patent/ES8604157A1/es not_active Expired
- 1985-08-02 EP EP85305537A patent/EP0171277A3/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
PT80898A (en) | 1985-09-01 |
EP0171277A3 (en) | 1987-11-19 |
GR851893B (ko) | 1985-12-03 |
ES8604157A1 (es) | 1986-01-16 |
KR870000623B1 (ko) | 1987-03-26 |
DK349385D0 (da) | 1985-08-01 |
IL75992A0 (en) | 1985-12-31 |
FI852975A0 (fi) | 1985-08-01 |
AU4573885A (en) | 1986-02-06 |
ES545860A0 (es) | 1986-01-16 |
HUT40656A (en) | 1987-01-28 |
DK349385A (da) | 1986-02-04 |
AU579172B2 (en) | 1988-11-17 |
EP0171277A2 (en) | 1986-02-12 |
PT80898B (pt) | 1987-12-30 |
EG17490A (en) | 1992-06-30 |
FI852975L (fi) | 1986-02-04 |
NZ212947A (en) | 1988-07-28 |
AR242033A1 (es) | 1993-02-26 |
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