KR840000491A - 설피민의 제조방법 - Google Patents
설피민의 제조방법 Download PDFInfo
- Publication number
- KR840000491A KR840000491A KR1019820003316A KR820003316A KR840000491A KR 840000491 A KR840000491 A KR 840000491A KR 1019820003316 A KR1019820003316 A KR 1019820003316A KR 820003316 A KR820003316 A KR 820003316A KR 840000491 A KR840000491 A KR 840000491A
- Authority
- KR
- South Korea
- Prior art keywords
- group
- formula
- carbon atoms
- compound
- reaction
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 12
- 150000001875 compounds Chemical class 0.000 claims 10
- 238000000034 method Methods 0.000 claims 10
- 125000000217 alkyl group Chemical group 0.000 claims 6
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 5
- 125000003545 alkoxy group Chemical group 0.000 claims 4
- 239000002253 acid Substances 0.000 claims 3
- 125000005843 halogen group Chemical group 0.000 claims 3
- -1 mercapto compound Chemical class 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- 150000001447 alkali salts Chemical class 0.000 claims 2
- 150000001732 carboxylic acid derivatives Chemical class 0.000 claims 2
- 239000011541 reaction mixture Substances 0.000 claims 2
- 239000002904 solvent Substances 0.000 claims 2
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 claims 2
- 150000003462 sulfoxides Chemical class 0.000 claims 2
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 claims 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 1
- 125000002252 acyl group Chemical group 0.000 claims 1
- 125000002947 alkylene group Chemical group 0.000 claims 1
- 150000001408 amides Chemical class 0.000 claims 1
- 238000009835 boiling Methods 0.000 claims 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 1
- 239000007795 chemical reaction product Substances 0.000 claims 1
- 229910052801 chlorine Inorganic materials 0.000 claims 1
- 239000000460 chlorine Substances 0.000 claims 1
- 125000000753 cycloalkyl group Chemical group 0.000 claims 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 claims 1
- 125000005059 halophenyl group Chemical group 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 150000002440 hydroxy compounds Chemical class 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 125000001624 naphthyl group Chemical group 0.000 claims 1
- 230000000269 nucleophilic effect Effects 0.000 claims 1
- 150000007530 organic bases Chemical group 0.000 claims 1
- 239000007800 oxidant agent Substances 0.000 claims 1
- 125000004076 pyridyl group Chemical group 0.000 claims 1
- 125000001424 substituent group Chemical group 0.000 claims 1
- 150000003568 thioethers Chemical class 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEP31.29444.8 | 1981-07-25 | ||
| DE19813129444 DE3129444A1 (de) | 1981-07-25 | 1981-07-25 | "sulfoximine, deren herstellung und diese verbindungen enthaltende arzneimittel" |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR840000491A true KR840000491A (ko) | 1984-02-22 |
Family
ID=6137766
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019820003316A KR840000491A (ko) | 1981-07-25 | 1982-07-24 | 설피민의 제조방법 |
Country Status (19)
| Country | Link |
|---|---|
| JP (1) | JPS5824559A (da) |
| KR (1) | KR840000491A (da) |
| AR (1) | AR230745A1 (da) |
| AU (1) | AU556082B2 (da) |
| CA (1) | CA1175430A (da) |
| CS (1) | CS236488B2 (da) |
| DD (1) | DD202871A5 (da) |
| DE (2) | DE3129444A1 (da) |
| DK (1) | DK329582A (da) |
| ES (4) | ES514275A0 (da) |
| FI (1) | FI822550L (da) |
| GR (1) | GR76181B (da) |
| HU (1) | HU188188B (da) |
| NO (1) | NO822255L (da) |
| PL (1) | PL137725B1 (da) |
| PT (1) | PT75297A (da) |
| SU (1) | SU1158041A3 (da) |
| YU (1) | YU158182A (da) |
| ZA (1) | ZA825273B (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2712367C (en) * | 2008-01-17 | 2016-01-19 | Bayer Schering Pharma Aktiengesellschaft | Sulphoximine-substituted quinazoline derivatives as immunomodulators, their preparation and use as medicaments |
-
1981
- 1981-07-25 DE DE19813129444 patent/DE3129444A1/de not_active Withdrawn
-
1982
- 1982-06-30 NO NO822255A patent/NO822255L/no unknown
- 1982-07-16 SU SU823463928A patent/SU1158041A3/ru active
- 1982-07-20 FI FI822550A patent/FI822550L/fi not_active Application Discontinuation
- 1982-07-20 YU YU01581/82A patent/YU158182A/xx unknown
- 1982-07-21 PL PL1982237600A patent/PL137725B1/pl unknown
- 1982-07-21 DD DD82241832A patent/DD202871A5/de unknown
- 1982-07-21 AR AR290035A patent/AR230745A1/es active
- 1982-07-22 HU HU822373A patent/HU188188B/hu unknown
- 1982-07-22 CS CS825591A patent/CS236488B2/cs unknown
- 1982-07-22 DK DK329582A patent/DK329582A/da not_active Application Discontinuation
- 1982-07-22 PT PT75297A patent/PT75297A/pt unknown
- 1982-07-23 ZA ZA825273A patent/ZA825273B/xx unknown
- 1982-07-23 AU AU86378/82A patent/AU556082B2/en not_active Ceased
- 1982-07-23 GR GR68840A patent/GR76181B/el unknown
- 1982-07-23 CA CA000407915A patent/CA1175430A/en not_active Expired
- 1982-07-23 JP JP57128814A patent/JPS5824559A/ja active Pending
- 1982-07-23 ES ES514275A patent/ES514275A0/es active Granted
- 1982-07-24 KR KR1019820003316A patent/KR840000491A/ko unknown
- 1982-12-18 DE DE19823246980 patent/DE3246980A1/de not_active Withdrawn
-
1983
- 1983-01-07 ES ES518827A patent/ES8400411A1/es not_active Expired
- 1983-01-07 ES ES518828A patent/ES8400412A1/es not_active Expired
- 1983-01-07 ES ES518826A patent/ES518826A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ZA825273B (en) | 1984-03-28 |
| PL137725B1 (en) | 1986-07-31 |
| FI822550A0 (fi) | 1982-07-20 |
| JPS5824559A (ja) | 1983-02-14 |
| ES518827A0 (es) | 1983-10-16 |
| AR230745A1 (es) | 1984-06-29 |
| HU188188B (en) | 1986-03-28 |
| ES8305333A1 (es) | 1983-04-01 |
| DE3129444A1 (de) | 1983-02-10 |
| DD202871A5 (de) | 1983-10-05 |
| DE3246980A1 (de) | 1984-06-20 |
| CA1175430A (en) | 1984-10-02 |
| DK329582A (da) | 1983-01-26 |
| AU8637882A (en) | 1983-04-14 |
| GR76181B (da) | 1984-08-03 |
| ES514275A0 (es) | 1983-04-01 |
| ES8400410A1 (es) | 1983-10-16 |
| AU556082B2 (en) | 1986-10-23 |
| PT75297A (fr) | 1982-08-01 |
| SU1158041A3 (ru) | 1985-05-23 |
| NO822255L (no) | 1983-01-26 |
| CS236488B2 (en) | 1985-05-15 |
| ES518828A0 (es) | 1983-10-16 |
| ES518826A0 (es) | 1983-10-16 |
| FI822550L (fi) | 1983-01-26 |
| ES8400412A1 (es) | 1983-10-16 |
| ES8400411A1 (es) | 1983-10-16 |
| PL237600A1 (en) | 1983-03-28 |
| YU158182A (en) | 1984-08-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR840009098A (ko) | 플루오로 알콕시 화합물의 제조방법 | |
| GB1340911A (en) | 3,4-dihydro-1,2,3-oxathiazin-4-one derivatives and a process for their preparation | |
| KR870003100A (ko) | 벤즈이미다졸 유도체 | |
| Anzai | Alkyl‐and arylthiation of uracil and indole | |
| KR840000491A (ko) | 설피민의 제조방법 | |
| KR860001065A (ko) | 4-아세톡시-3-히드록시에틸아제티진-2-온유도체의 제조방법 | |
| KR830007554A (ko) | 인돌리논의 제조방법 | |
| KR840006487A (ko) | 세팔로스포린의 제조방법 | |
| KR850004749A (ko) | 디페닐 에테르 제초제의 제조방법 | |
| KR840004736A (ko) | 벤즈옥사진 -2- 온의 제조방법 | |
| KR840005723A (ko) | 티아졸유도체의 제조방법 | |
| KR840006335A (ko) | 치환된 벤젠설폰산 에스테르의 제조방법 | |
| KR840004089A (ko) | 구아니디노 헤테로사이클릭페닐아미딘의 제조방법 | |
| GB1156005A (en) | Process for the production of Aminophenyl Thioethers | |
| US3317575A (en) | Heterocycles having in the ring thereof an element from group v-a | |
| KR830007639A (ko) | 락탐 화합물의 제조방법 | |
| KR870010006A (ko) | 1-아릴-5-아미노-피라졸의 제조방법 | |
| KR860000295A (ko) | 옥시캄 유도체의 제조방법 | |
| KR840008647A (ko) | 대칭 1,4-디하이드로피리딘디카복실 에스테르의 제조방법 | |
| CA1210015A (en) | Industrial process for oxidizing thioethers or thiolcarboxylic acid derivatives | |
| KR870002152A (ko) | 1-데티아-2-티아 세팔로스포란산 유도체 및 이들의 염의 제조방법 | |
| US3118891A (en) | Disulfamic acids and related compounds | |
| KR910021360A (ko) | 하이드록시카보닐 유도체 및 이의 제조방법 | |
| KR850006422A (ko) | 세팔로스포린 유도체의 제조방법 | |
| KR840004759A (ko) | 페니실린과 세팔로스포린 화합물의 제조방법 및 이들의 제조에 사용한 새로운 중간체의 제조방법 |