KR830007552A - 3-(피리드-3- 또는 -4-일알킬) 인돌의 제조방법 - Google Patents

3-(피리드-3- 또는 -4-일알킬) 인돌의 제조방법 Download PDF

Info

Publication number
KR830007552A
KR830007552A KR1019810004911A KR810004911A KR830007552A KR 830007552 A KR830007552 A KR 830007552A KR 1019810004911 A KR1019810004911 A KR 1019810004911A KR 810004911 A KR810004911 A KR 810004911A KR 830007552 A KR830007552 A KR 830007552A
Authority
KR
South Korea
Prior art keywords
compound
formula
alkyl
coo
cooh
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1019810004911A
Other languages
English (en)
Korean (ko)
Inventor
에드워드 크로쓰 피터
피터 딕킨슨 로저
Original Assignee
윌리암 존 윌슨
화이자 코포레이숀
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 윌리암 존 윌슨, 화이자 코포레이숀 filed Critical 윌리암 존 윌슨
Publication of KR830007552A publication Critical patent/KR830007552A/ko
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
KR1019810004911A 1980-12-15 1981-12-14 3-(피리드-3- 또는 -4-일알킬) 인돌의 제조방법 Withdrawn KR830007552A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8040081 1980-12-15
GB8040081 1980-12-15

Publications (1)

Publication Number Publication Date
KR830007552A true KR830007552A (ko) 1983-10-21

Family

ID=10517993

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019810004911A Withdrawn KR830007552A (ko) 1980-12-15 1981-12-14 3-(피리드-3- 또는 -4-일알킬) 인돌의 제조방법

Country Status (22)

Country Link
US (1) US4363912A (enExample)
EP (1) EP0054417B1 (enExample)
JP (1) JPS57181082A (enExample)
KR (1) KR830007552A (enExample)
AR (1) AR229110A1 (enExample)
AU (1) AU525296B2 (enExample)
CA (1) CA1143737A (enExample)
CS (1) CS228527B2 (enExample)
DD (1) DD202290A5 (enExample)
DE (1) DE3167879D1 (enExample)
DK (1) DK552581A (enExample)
ES (1) ES8308872A1 (enExample)
FI (1) FI814003A7 (enExample)
GR (1) GR76355B (enExample)
IE (1) IE51949B1 (enExample)
IL (1) IL64534A0 (enExample)
NO (1) NO814264L (enExample)
PH (1) PH17576A (enExample)
PL (1) PL133634B1 (enExample)
PT (1) PT74123B (enExample)
YU (1) YU293481A (enExample)
ZA (1) ZA818665B (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS229934B2 (en) * 1981-07-07 1984-07-16 Pfizer Production method subst.indolylacryte acid derivative
US4460777A (en) * 1981-11-19 1984-07-17 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4478842A (en) * 1981-11-19 1984-10-23 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4536505A (en) * 1983-05-17 1985-08-20 Ciba-Geigy Corporation Certain N-(pyridyl) indoles
US4511573A (en) * 1983-05-17 1985-04-16 Ciba-Geigy Corporation 3-Substituted-2-(heteroaryl) indoles
GB8524157D0 (en) * 1984-10-19 1985-11-06 Ici America Inc Heterocyclic amides
US4609733A (en) * 1984-12-27 1986-09-02 Ciba-Geigy Corporation 3-keto-substituted-N-pyridylindoles
GB8609175D0 (en) * 1986-04-15 1986-05-21 Ici America Inc Heterocyclic carboxamides
ATE269861T1 (de) * 1998-03-31 2004-07-15 Inst For Pharm Discovery Inc Substituierte indolalkansäure
TNSN99224A1 (fr) * 1998-12-01 2005-11-10 Inst For Pharm Discovery Inc Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique
WO2001051489A2 (en) * 2000-01-14 2001-07-19 The Institutes For Pharmaceutical Discovery, Llc Methods for lowering uric acid levels
ES2268480T3 (es) * 2002-12-10 2007-03-16 Wyeth Derivados del acido 3-alquilo- y 3-arilalquilo-1h-indol-1-il-acetico sustituidos como inhibidores del inhibidor del activador del plasminogeno-1 (pai-1).
GB0324763D0 (en) * 2003-10-23 2003-11-26 Oxagen Ltd Use of compounds in therapy
EP2046740B1 (en) 2006-07-22 2012-05-23 Oxagen Limited Compounds having crth2 antagonist activity
KR20100067677A (ko) * 2007-09-24 2010-06-21 알러간, 인코포레이티드 스핑고신-1-포스페이트 (ｓｐ1) 생물학적 활성을 갖는 아릴 또는 헤테로아릴 기를 함유하는 인돌 화합물
AU2009204700B2 (en) * 2008-01-18 2013-07-04 Atopix Therapeutics Limited Compounds having CRTH2 antagonist activity
US7750027B2 (en) * 2008-01-18 2010-07-06 Oxagen Limited Compounds having CRTH2 antagonist activity
JP2011509991A (ja) * 2008-01-22 2011-03-31 オキサジェン リミテッド Ｃｒｔｈ２アンタゴニスト活性を有する化合物
WO2009093026A1 (en) 2008-01-22 2009-07-30 Oxagen Limited Compounds having crth2 antagonist activity
GB201322273D0 (en) 2013-12-17 2014-01-29 Atopix Therapeutics Ltd Process
GB201407820D0 (en) * 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form
GB201407807D0 (en) * 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5173M (enExample) * 1966-02-11 1967-06-19
FR7337M (enExample) * 1968-01-11 1969-10-13
GB2045244B (en) 1979-03-07 1983-01-26 Pfizer Ltd 3-1-(imidazolylalkyl) indoles
US4322533A (en) * 1980-03-17 1982-03-30 Lesher George Y 1H-Indole-2,3-dione derivatives

Also Published As

Publication number Publication date
CA1143737A (en) 1983-03-29
DK552581A (da) 1982-06-16
PT74123A (en) 1982-01-01
AR229110A1 (es) 1983-06-15
JPS57181082A (en) 1982-11-08
FI814003L (fi) 1982-06-16
IL64534A0 (en) 1982-03-31
NO814264L (no) 1982-06-16
ZA818665B (en) 1982-10-27
PH17576A (en) 1984-10-01
FI814003A7 (fi) 1982-06-16
ES507960A0 (es) 1983-10-01
AU525296B2 (en) 1982-10-28
CS228527B2 (en) 1984-05-14
PL133634B1 (en) 1985-06-29
EP0054417A1 (en) 1982-06-23
IE51949B1 (en) 1987-04-29
EP0054417B1 (en) 1984-12-19
US4363912A (en) 1982-12-14
PL234253A1 (en) 1983-05-23
DD202290A5 (de) 1983-09-07
DE3167879D1 (en) 1985-01-31
AU7848881A (en) 1982-06-24
YU293481A (en) 1984-10-31
GR76355B (enExample) 1984-08-06
PT74123B (en) 1983-12-19
ES8308872A1 (es) 1983-10-01
IE812928L (en) 1982-06-15

Similar Documents

Publication Publication Date Title
KR830007552A (ko) 3-(피리드-3- 또는 -4-일알킬) 인돌의 제조방법
EP0744400A3 (en) Process for the preparation of 4-trifluoromethylnicotinic acid
PL291470A1 (en) Method of obtaining novel urea derivatives
PH15864A (en) 2-(2-alkoxy-methyl)-2-hydroxy-6-7 benzomorphans and salts thereof
GB1542112A (en) Process for the preparation of 2-phenylethanol or derivatives thereof
ES8703451A1 (es) Procedimiento para preparar acido 1,2-ditiolan-3-pentanoico (acido tioctico)
EP0711762A4 (en) METHOD FOR PRODUCING TETRAZOLIC COMPOUNDS AND INTERMEDIATE PRODUCTS USED THEREOF
KR850000438A (ko) 페녹시 유도체의 제조방법
ES8200643A1 (es) Derivador del acido ciclohexano carboxilico
KR890014435A (ko) 페녹시알킬카복실산 유도체 및 이의 제조방법
US3979506A (en) Radioactive compounds for labeling proteins
KR850002459A (ko) 디히드록시벤즈아미드 유도체 및 그 제조방법
KR840000529A (ko) 인돌 유도체의 제조방법
JPS5551041A (en) Phenyl-fatty acid derivative
GB1432649A (enExample)
JPS5549352A (en) Cyclic iminocarboxylic acid derivative and its salt
IE792508L (en) Piperidylindoles
GB1446632A (en) 5-endo-benzoyloxy-n-amino-c2-4 alkyl- bicyclo-2,2,1-heptane - 2,3-d-endo-carboxylic acid imides
KR840001974A (ko) 1-[3-(6-플루오로-1,2-벤즈이속사졸-3-일)프로필]-4-(치환된)-피페라진 및-피레리딘의 제조방법
NZ503916A (en) Method of synthesis of pyrrole and indole amides
JPH11193290A5 (enExample)
US6437169B1 (en) 1-naphthol compound and method for preparing compound having acidic proton using the same
JPS57130972A (en) Preparation of indole derivative
IE831074L (en) Preparation of thiophene-2-acetic acids
JPS5785386A (en) Novel quinolinic acid imide a compound

Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19811214

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination