KR820002345B1 - 에탐부톨술폰산 유도체의 제조방법 - Google Patents

에탐부톨술폰산 유도체의 제조방법 Download PDF

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Publication number
KR820002345B1
KR820002345B1 KR1019810002455A KR810002455A KR820002345B1 KR 820002345 B1 KR820002345 B1 KR 820002345B1 KR 1019810002455 A KR1019810002455 A KR 1019810002455A KR 810002455 A KR810002455 A KR 810002455A KR 820002345 B1 KR820002345 B1 KR 820002345B1
Authority
KR
South Korea
Prior art keywords
etambutol
formula
reaction
methanesulfonate
mol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR1019810002455A
Other languages
English (en)
Korean (ko)
Inventor
박상우
김원태
Original Assignee
한국과학기술원
임관
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 한국과학기술원, 임관 filed Critical 한국과학기술원
Priority to KR1019810002455A priority Critical patent/KR820002345B1/ko
Priority to US06/387,037 priority patent/US4450274A/en
Priority to JP57107679A priority patent/JPS588065A/ja
Application granted granted Critical
Publication of KR820002345B1 publication Critical patent/KR820002345B1/ko
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/86—Hydrazides; Thio or imino analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
KR1019810002455A 1981-07-07 1981-07-07 에탐부톨술폰산 유도체의 제조방법 Expired KR820002345B1 (ko)

Priority Applications (3)

Application Number Priority Date Filing Date Title
KR1019810002455A KR820002345B1 (ko) 1981-07-07 1981-07-07 에탐부톨술폰산 유도체의 제조방법
US06/387,037 US4450274A (en) 1981-07-07 1982-06-10 Preparation of ethambutol-diisoniazide methane sulfonic acid salt
JP57107679A JPS588065A (ja) 1981-07-07 1982-06-24 エタンブト−ルスルホン酸誘導体の製造方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019810002455A KR820002345B1 (ko) 1981-07-07 1981-07-07 에탐부톨술폰산 유도체의 제조방법

Publications (1)

Publication Number Publication Date
KR820002345B1 true KR820002345B1 (ko) 1982-12-23

Family

ID=19221302

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019810002455A Expired KR820002345B1 (ko) 1981-07-07 1981-07-07 에탐부톨술폰산 유도체의 제조방법

Country Status (3)

Country Link
US (1) US4450274A (enExample)
JP (1) JPS588065A (enExample)
KR (1) KR820002345B1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2211035C1 (ru) * 2002-03-18 2003-08-27 Государственное федеральное учреждение Уральский научно-исследовательский институт фтизиопульмонологии Противотуберкулезный препарат
US7456222B2 (en) * 2002-05-17 2008-11-25 Sequella, Inc. Anti tubercular drug: compositions and methods
CN101404986B (zh) * 2002-05-17 2011-09-28 赛奎拉公司 用于诊断和治疗感染性疾病的组合物和制药方法
US20040033986A1 (en) * 2002-05-17 2004-02-19 Protopopova Marina Nikolaevna Anti tubercular drug: compositions and methods
EP1670314A4 (en) * 2003-09-05 2009-02-25 Sequella Inc METHODS AND COMPOSITIONS INCLUDE DIAMINE AS A NEW THERAPEUTIC FOR TUBERCULOSIS
US20090281054A1 (en) * 2008-05-06 2009-11-12 Venkata Reddy Compositions and methods comprising capuramycin analogues

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES369952A1 (es) * 1969-07-28 1971-07-16 Ferrer Labor Procedimiento de fabricacion de un nuevo derivado dihidra- cinico de accion antituberculosa.

Also Published As

Publication number Publication date
JPS612668B2 (enExample) 1986-01-27
JPS588065A (ja) 1983-01-18
US4450274A (en) 1984-05-22

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KR890000993B1 (ko) 3-{{{2-{(엔-알킬아미노이미노메틸)아미노}-4-티아졸릴}메틸}티오}-엔-(아랄킬아미노술포닐)프로판이미드아미드 유도체의 제조방법

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