KR20240073943A - 화합물 또는 그의 약학적으로 허용되는 염의 제조 방법 - Google Patents

화합물 또는 그의 약학적으로 허용되는 염의 제조 방법 Download PDF

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Publication number
KR20240073943A
KR20240073943A KR1020247014478A KR20247014478A KR20240073943A KR 20240073943 A KR20240073943 A KR 20240073943A KR 1020247014478 A KR1020247014478 A KR 1020247014478A KR 20247014478 A KR20247014478 A KR 20247014478A KR 20240073943 A KR20240073943 A KR 20240073943A
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South Korea
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compound
crystal
formula
solvent
carbon atoms
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Pending
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KR1020247014478A
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English (en)
Korean (ko)
Inventor
료 미나미카와
아키라 마츠타니
유야 마가타
신지 가와니시
미즈키 가와히라
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이에이 파마 가부시키가이샤
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Publication of KR20240073943A publication Critical patent/KR20240073943A/ko
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1020247014478A 2021-10-05 2022-10-04 화합물 또는 그의 약학적으로 허용되는 염의 제조 방법 Pending KR20240073943A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021164171 2021-10-05
JPJP-P-2021-164171 2021-10-05
PCT/JP2022/037098 WO2023058645A1 (ja) 2021-10-05 2022-10-04 化合物又はその薬学的に許容される塩の製造方法

Publications (1)

Publication Number Publication Date
KR20240073943A true KR20240073943A (ko) 2024-05-27

Family

ID=85803498

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020247014478A Pending KR20240073943A (ko) 2021-10-05 2022-10-04 화합물 또는 그의 약학적으로 허용되는 염의 제조 방법

Country Status (11)

Country Link
US (1) US20240262805A1 (https=)
EP (1) EP4414362A4 (https=)
JP (1) JPWO2023058645A1 (https=)
KR (1) KR20240073943A (https=)
CN (1) CN118055925A (https=)
AU (1) AU2022361862A1 (https=)
CA (1) CA3234498A1 (https=)
IL (1) IL311879A (https=)
MX (1) MX2024004049A (https=)
TW (1) TW202330490A (https=)
WO (1) WO2023058645A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116947658B (zh) * 2023-07-28 2025-10-28 南通华祥医药科技有限公司 一种1-氨基-2-甲基-2-丙醇的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3269772B1 (en) * 2015-03-10 2020-11-11 Unimatec Co., Ltd. Fluorine-containing boric acid/pvb composite
ES2856125T3 (es) 2016-02-05 2021-09-27 Ea Pharma Co Ltd Derivado de sulfonamida y composición farmacéutica que contiene la misma
TW201731824A (zh) * 2016-02-05 2017-09-16 Ea Pharma Co Ltd α４β７整合蛋白抑制劑
JP2019031449A (ja) * 2017-08-04 2019-02-28 Ｅａファーマ株式会社 スルホンアミド誘導体及びそれを含有する医薬組成物

Also Published As

Publication number Publication date
EP4414362A4 (en) 2025-09-03
IL311879A (en) 2024-06-01
WO2023058645A1 (ja) 2023-04-13
CA3234498A1 (en) 2023-04-13
AU2022361862A1 (en) 2024-04-18
JPWO2023058645A1 (https=) 2023-04-13
CN118055925A (zh) 2024-05-17
US20240262805A1 (en) 2024-08-08
MX2024004049A (es) 2024-04-25
TW202330490A (zh) 2023-08-01
EP4414362A1 (en) 2024-08-14

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PA0105 International application

Patent event date: 20240430

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20250626

Comment text: Request for Examination of Application