CN118055925A - 化合物或其药学上允许的盐的制造方法 - Google Patents
化合物或其药学上允许的盐的制造方法 Download PDFInfo
- Publication number
- CN118055925A CN118055925A CN202280067043.4A CN202280067043A CN118055925A CN 118055925 A CN118055925 A CN 118055925A CN 202280067043 A CN202280067043 A CN 202280067043A CN 118055925 A CN118055925 A CN 118055925A
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- CN
- China
- Prior art keywords
- compound
- formula
- crystal
- following
- synthesis route
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021164171 | 2021-10-05 | ||
| JP2021-164171 | 2021-10-05 | ||
| PCT/JP2022/037098 WO2023058645A1 (ja) | 2021-10-05 | 2022-10-04 | 化合物又はその薬学的に許容される塩の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN118055925A true CN118055925A (zh) | 2024-05-17 |
Family
ID=85803498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202280067043.4A Pending CN118055925A (zh) | 2021-10-05 | 2022-10-04 | 化合物或其药学上允许的盐的制造方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20240262805A1 (https=) |
| EP (1) | EP4414362A4 (https=) |
| JP (1) | JPWO2023058645A1 (https=) |
| KR (1) | KR20240073943A (https=) |
| CN (1) | CN118055925A (https=) |
| AU (1) | AU2022361862A1 (https=) |
| CA (1) | CA3234498A1 (https=) |
| IL (1) | IL311879A (https=) |
| MX (1) | MX2024004049A (https=) |
| TW (1) | TW202330490A (https=) |
| WO (1) | WO2023058645A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116947658B (zh) * | 2023-07-28 | 2025-10-28 | 南通华祥医药科技有限公司 | 一种1-氨基-2-甲基-2-丙醇的合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3269772B1 (en) * | 2015-03-10 | 2020-11-11 | Unimatec Co., Ltd. | Fluorine-containing boric acid/pvb composite |
| ES2856125T3 (es) | 2016-02-05 | 2021-09-27 | Ea Pharma Co Ltd | Derivado de sulfonamida y composición farmacéutica que contiene la misma |
| TW201731824A (zh) * | 2016-02-05 | 2017-09-16 | Ea Pharma Co Ltd | α４β７整合蛋白抑制劑 |
| JP2019031449A (ja) * | 2017-08-04 | 2019-02-28 | Ｅａファーマ株式会社 | スルホンアミド誘導体及びそれを含有する医薬組成物 |
-
2022
- 2022-10-04 WO PCT/JP2022/037098 patent/WO2023058645A1/ja not_active Ceased
- 2022-10-04 AU AU2022361862A patent/AU2022361862A1/en active Pending
- 2022-10-04 CA CA3234498A patent/CA3234498A1/en active Pending
- 2022-10-04 TW TW111137652A patent/TW202330490A/zh unknown
- 2022-10-04 EP EP22878513.5A patent/EP4414362A4/en active Pending
- 2022-10-04 JP JP2023552896A patent/JPWO2023058645A1/ja active Pending
- 2022-10-04 MX MX2024004049A patent/MX2024004049A/es unknown
- 2022-10-04 CN CN202280067043.4A patent/CN118055925A/zh active Pending
- 2022-10-04 KR KR1020247014478A patent/KR20240073943A/ko active Pending
- 2022-10-04 IL IL311879A patent/IL311879A/en unknown
-
2024
- 2024-04-02 US US18/624,295 patent/US20240262805A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP4414362A4 (en) | 2025-09-03 |
| IL311879A (en) | 2024-06-01 |
| WO2023058645A1 (ja) | 2023-04-13 |
| CA3234498A1 (en) | 2023-04-13 |
| AU2022361862A1 (en) | 2024-04-18 |
| JPWO2023058645A1 (https=) | 2023-04-13 |
| KR20240073943A (ko) | 2024-05-27 |
| US20240262805A1 (en) | 2024-08-08 |
| MX2024004049A (es) | 2024-04-25 |
| TW202330490A (zh) | 2023-08-01 |
| EP4414362A1 (en) | 2024-08-14 |
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| PB01 | Publication | ||
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| SE01 | Entry into force of request for substantive examination | ||
| REG | Reference to a national code |
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