KR20230167379A - 폴리하이드록시알칸산(pha)을 포함하는 미립자 및 그 제조방법 - Google Patents
폴리하이드록시알칸산(pha)을 포함하는 미립자 및 그 제조방법 Download PDFInfo
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- KR20230167379A KR20230167379A KR1020237036769A KR20237036769A KR20230167379A KR 20230167379 A KR20230167379 A KR 20230167379A KR 1020237036769 A KR1020237036769 A KR 1020237036769A KR 20237036769 A KR20237036769 A KR 20237036769A KR 20230167379 A KR20230167379 A KR 20230167379A
- Authority
- KR
- South Korea
- Prior art keywords
- pha
- acid
- fine particles
- microparticles
- polyhydroxyalkanoic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 235000010755 mineral Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 239000012046 mixed solvent Substances 0.000 description 1
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 1
- 235000019796 monopotassium phosphate Nutrition 0.000 description 1
- 229910000403 monosodium phosphate Inorganic materials 0.000 description 1
- 235000019799 monosodium phosphate Nutrition 0.000 description 1
- 125000001400 nonyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- JFNLZVQOOSMTJK-KNVOCYPGSA-N norbornene Chemical compound C1[C@@H]2CC[C@H]1C=C2 JFNLZVQOOSMTJK-KNVOCYPGSA-N 0.000 description 1
- 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 235000014593 oils and fats Nutrition 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 229920000620 organic polymer Polymers 0.000 description 1
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000003973 paint Substances 0.000 description 1
- 125000001147 pentyl group Chemical group C(CCCC)* 0.000 description 1
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- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920001020 poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) Polymers 0.000 description 1
- 229920001013 poly(3-hydroxybutyrate-co-4-hydroxybutyrate) Polymers 0.000 description 1
- 229920001652 poly(etherketoneketone) Polymers 0.000 description 1
- 229920000747 poly(lactic acid) Polymers 0.000 description 1
- 229920002791 poly-4-hydroxybutyrate Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
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- 229920000647 polyepoxide Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
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- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 description 1
- OTYBMLCTZGSZBG-UHFFFAOYSA-L potassium sulfate Chemical compound [K+].[K+].[O-]S([O-])(=O)=O OTYBMLCTZGSZBG-UHFFFAOYSA-L 0.000 description 1
- 229910052939 potassium sulfate Inorganic materials 0.000 description 1
- 235000011151 potassium sulphates Nutrition 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 235000003441 saturated fatty acids Nutrition 0.000 description 1
- 238000001878 scanning electron micrograph Methods 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
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- 239000011734 sodium Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
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- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- XYGBKMMCQDZQOZ-UHFFFAOYSA-M sodium;4-hydroxybutanoate Chemical compound [Na+].OCCCC([O-])=O XYGBKMMCQDZQOZ-UHFFFAOYSA-M 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
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- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 229920005992 thermoplastic resin Polymers 0.000 description 1
- 229920001187 thermosetting polymer Polymers 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 125000002889 tridecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 238000009966 trimming Methods 0.000 description 1
- PHYFQTYBJUILEZ-IUPFWZBJSA-N triolein Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC(OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCCCC PHYFQTYBJUILEZ-IUPFWZBJSA-N 0.000 description 1
- 239000011882 ultra-fine particle Substances 0.000 description 1
- 125000002948 undecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 238000004065 wastewater treatment Methods 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical compound [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 description 1
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 description 1
- 229910000368 zinc sulfate Inorganic materials 0.000 description 1
- 229960001763 zinc sulfate Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/12—Powdering or granulating
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
- C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L101/00—Compositions of unspecified macromolecular compounds
- C08L101/16—Compositions of unspecified macromolecular compounds the macromolecular compounds being biodegradable
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
- C08L67/04—Polyesters derived from hydroxycarboxylic acids, e.g. lactones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
- C12P7/625—Polyesters of hydroxy carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G2230/00—Compositions for preparing biodegradable polymers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2367/00—Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Derivatives of such polymers
- C08J2367/04—Polyesters derived from hydroxy carboxylic acids, e.g. lactones
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2201/00—Properties
- C08L2201/06—Biodegradable
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
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- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biological Depolymerization Polymers (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| JP2021064686 | 2021-04-06 | ||
| JPJP-P-2021-064686 | 2021-04-06 | ||
| PCT/JP2022/016649 WO2022215653A1 (ja) | 2021-04-06 | 2022-03-31 | ポリヒドロキシアルカン酸（ｐｈａ）を含む微粒子及びその製造方法 |
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| KR20230167379A true KR20230167379A (ko) | 2023-12-08 |
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| EP (1) | EP4321557A4 (https=) |
| JP (1) | JPWO2022215653A1 (https=) |
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| CN (1) | CN117460764A (https=) |
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| CN120192646B (zh) * | 2025-05-27 | 2025-12-26 | 都佰城新材料技术（上海）有限公司 | 一种pha纳米水性悬浮液及其制备方法与应用 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| KR100463619B1 (ko) | 2001-07-09 | 2004-12-30 | 산요덴키가부시키가이샤 | 차지펌프 회로의 제어 방법 |
| KR20170056908A (ko) | 2015-11-16 | 2017-05-24 | 한국항공우주연구원 | 다이어프램 방식 극저온 밸브 |
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| JP5133478B2 (ja) | 2001-06-12 | 2013-01-30 | ユニチカ株式会社 | 生分解性ポリエステル樹脂微粒子の製造方法 |
| TW200508393A (en) * | 2003-01-20 | 2005-03-01 | Kaneka Corp | Method of collecting highly pure polyhydroxyalkanoate from microbial cells |
| JP2004250629A (ja) * | 2003-02-21 | 2004-09-09 | Kanegafuchi Chem Ind Co Ltd | ポリヒドロキシアルカン酸の製造方法 |
| ES2362221T3 (es) | 2005-01-28 | 2011-06-29 | Tepha, Inc. | Embolización con partículas poli-4-hidroxibutirato. |
| WO2009060898A1 (ja) | 2007-11-07 | 2009-05-14 | Fuence Co., Ltd. | 固定化装置 |
| WO2009158724A2 (en) | 2008-06-27 | 2009-12-30 | Tepha, Inc. | Improved injectable delivery of microparticles and compositions therefore |
| CA2802212C (en) | 2010-06-15 | 2015-03-24 | Tepha, Inc. | Medical devices containing dry spun non-wovens of poly-4-hydroxybutyrate and copolymers |
| JP6065757B2 (ja) * | 2013-06-14 | 2017-01-25 | コニカミノルタ株式会社 | 静電荷像現像用トナー、その製造方法、及び画像形成方法 |
| JP6903009B2 (ja) * | 2015-09-30 | 2021-07-14 | 積水化成品工業株式会社 | 多孔質樹脂微粒子及びその製造方法 |
| US20190082719A1 (en) * | 2016-03-16 | 2019-03-21 | Kaneka Corporation | Feed composition, method for manufacturing zooplankton, zooplankton, and zooplankton growth promoter and survival rate enhancer |
| IT201700035338A1 (it) | 2017-03-30 | 2018-09-30 | Bio On Spa | Composizione cosmetica comprendente un poliestere biodegradabile e una fase oleosa. |
| US11332612B2 (en) * | 2017-04-05 | 2022-05-17 | Kaneka Corporation | Polyhydroxyalkanoate particles and aqueous dispersion of same |
| JP6319506B1 (ja) | 2017-11-02 | 2018-05-09 | オムロン株式会社 | 評価装置、評価システム、車両、およびプログラム |
| US20200268637A1 (en) * | 2019-02-26 | 2020-08-27 | Micro Powders, Inc. | Ultrafine Polyhydroxyalkanoates |
| US12534567B2 (en) * | 2019-04-26 | 2026-01-27 | Fuence Co., Ltd. | Polyhydroxyalkanoic acid and method for producing same |
| WO2021059762A1 (ja) * | 2019-09-25 | 2021-04-01 | 株式会社カネカ | ポリヒドロキシアルカン酸の製造方法 |
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2022
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- 2022-03-31 KR KR1020237036769A patent/KR20230167379A/ko active Pending
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- 2022-03-31 EP EP22784637.5A patent/EP4321557A4/en active Pending
- 2022-03-31 WO PCT/JP2022/016649 patent/WO2022215653A1/ja not_active Ceased
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100463619B1 (ko) | 2001-07-09 | 2004-12-30 | 산요덴키가부시키가이샤 | 차지펌프 회로의 제어 방법 |
| KR20170056908A (ko) | 2015-11-16 | 2017-05-24 | 한국항공우주연구원 | 다이어프램 방식 극저온 밸브 |
Non-Patent Citations (2)
| Title |
|---|
| [비특허문헌 0001] 헤세이 28년도 화학물질 안전 대책(마이크로 플라스틱 국내 배출 실태 조사) 보고서 헤세이 29년도 2월 JFE 테크노리서치 주식회사 헤세이 28년도 경제산업성 위탁 조사 보고서 |
| [비특허문헌 0002] Microparticals, Microspheres, and Microcapsules for Advanced, Drug, Deliver Pharm. 2019, 87,20 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN117460764A (zh) | 2024-01-26 |
| US20240368355A1 (en) | 2024-11-07 |
| EP4321557A4 (en) | 2025-04-16 |
| WO2022215653A1 (ja) | 2022-10-13 |
| EP4321557A1 (en) | 2024-02-14 |
| JPWO2022215653A1 (https=) | 2022-10-13 |
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