KR20230157430A - Cns 및 전신 질병을 치료하기 위한 line-1 억제제 - Google Patents
Cns 및 전신 질병을 치료하기 위한 line-1 억제제 Download PDFInfo
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- KR20230157430A KR20230157430A KR1020237034983A KR20237034983A KR20230157430A KR 20230157430 A KR20230157430 A KR 20230157430A KR 1020237034983 A KR1020237034983 A KR 1020237034983A KR 20237034983 A KR20237034983 A KR 20237034983A KR 20230157430 A KR20230157430 A KR 20230157430A
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- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
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- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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Landscapes
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| PCT/US2022/020362 WO2022197689A1 (en) | 2021-03-15 | 2022-03-15 | Line-1 inhibitors to treat cns and systemic diseases |
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| US20250170158A1 (en) * | 2022-02-22 | 2025-05-29 | Rome Therapeutics, Inc. | Methods of treating medical conditions using censavudine or a related compound |
| IL315480A (en) | 2022-03-15 | 2024-11-01 | Rome Therapeutics Inc | Compounds and methods for treating disease |
| WO2023178128A1 (en) * | 2022-03-15 | 2023-09-21 | Rome Therapeutics, Inc. | Methods of treating medical conditions using islatravir or a related compound |
| CA3246792A1 (en) * | 2022-03-30 | 2023-10-05 | Transposon Therapeutics, Inc. | NUCLEOSIDE LINE-1 INHIBITORS |
| WO2024129788A1 (en) * | 2022-12-13 | 2024-06-20 | Brown University | Small molecule inhibitors of the line-1 endonuclease domain |
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| EP2965760A1 (en) * | 2014-07-09 | 2016-01-13 | Université de Montpellier | Combination of antiretroviral agents for use in the prevention or treatment of chronic inflammatory diseases |
| CN105012305A (zh) * | 2015-07-24 | 2015-11-04 | 福建广生堂药业股份有限公司 | 拉米夫定及其药用盐治疗老年性黄斑部病变的用途 |
| RU2726210C2 (ru) * | 2018-12-27 | 2020-07-09 | Общество С Ограниченной Ответственностью "Пролонгированные Лекарства" | Комбинация противовирусных средств, набор и способ лечения на ее основе |
| EP3914604B1 (en) * | 2019-01-25 | 2026-03-04 | Brown University | Compositions comprising censavudine or elvucitabine for treating age-associated inflammation and disorders |
| TW202104210A (zh) * | 2019-04-17 | 2021-02-01 | 美商基利科學股份有限公司 | Hiv蛋白酶抑制劑 |
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| AU2022237405A1 (en) | 2023-11-02 |
| UA130707C2 (uk) | 2026-04-22 |
| WO2022197689A1 (en) | 2022-09-22 |
| MA62910A1 (fr) | 2023-12-29 |
| EP4308237A1 (en) | 2024-01-24 |
| DOP2023000192A (es) | 2024-02-29 |
| CL2023002746A1 (es) | 2024-04-05 |
| EP4308237A4 (en) | 2025-03-05 |
| US20240173346A1 (en) | 2024-05-30 |
| CN117355312A (zh) | 2024-01-05 |
| MX2023010657A (es) | 2023-09-21 |
| BR112023018714A2 (pt) | 2023-10-24 |
| IL305869A (en) | 2023-11-01 |
| CA3211369A1 (en) | 2022-09-22 |
| JP2024511973A (ja) | 2024-03-18 |
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