KR20230157342A - 다중 치환기 실로시빈 유도체 및 사용 방법 - Google Patents
다중 치환기 실로시빈 유도체 및 사용 방법 Download PDFInfo
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- KR20230157342A KR20230157342A KR1020237031136A KR20237031136A KR20230157342A KR 20230157342 A KR20230157342 A KR 20230157342A KR 1020237031136 A KR1020237031136 A KR 1020237031136A KR 20237031136 A KR20237031136 A KR 20237031136A KR 20230157342 A KR20230157342 A KR 20230157342A
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- QKTAAWLCLHMUTJ-UHFFFAOYSA-N psilocybin Chemical class C1C=CC(OP(O)(O)=O)=C2C(CCN(C)C)=CN=C21 QKTAAWLCLHMUTJ-UHFFFAOYSA-N 0.000 title claims abstract description 482
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- UUEVFMOUBSLVJW-UHFFFAOYSA-N oxo-[[1-[2-[2-[2-[4-(oxoazaniumylmethylidene)pyridin-1-yl]ethoxy]ethoxy]ethyl]pyridin-4-ylidene]methyl]azanium;dibromide Chemical compound [Br-].[Br-].C1=CC(=C[NH+]=O)C=CN1CCOCCOCCN1C=CC(=C[NH+]=O)C=C1 UUEVFMOUBSLVJW-UHFFFAOYSA-N 0.000 claims description 214
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| PCT/CA2022/050206 WO2022170438A1 (en) | 2021-02-12 | 2022-02-11 | Multi-substituent psilocybin derivatives and methods of using |
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| US11312684B1 (en) | 2021-02-10 | 2022-04-26 | Eleusis Therapeutics Us, Inc. | Pharmaceutically acceptable salts of psilocin and uses thereof |
| CA3219577A1 (en) * | 2021-05-27 | 2022-12-01 | Nicholas Stuart William MILNE | Methods for producing tryptamine derivatives. |
| WO2023168023A1 (en) | 2022-03-04 | 2023-09-07 | Reset Pharmaceuticals, Inc. | Co-crystals or salts comprising psilocin |
| GB202315025D0 (en) * | 2023-09-29 | 2023-11-15 | Psylink Uab | Production and medical use of psilocybin and related compounds |
| WO2025099444A1 (en) * | 2023-11-09 | 2025-05-15 | Beckley Psytech Limited | N-Acetylserotonin (NAS) Analogues |
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| US3182071A (en) * | 1961-06-27 | 1965-05-04 | Warner Lambert Pharmaceutical | Acylated indole derivatives |
| US4803218A (en) * | 1982-09-29 | 1989-02-07 | Mcneilab, Inc. | 3-aminoalkyl-1H-indole-5-urea and amide derivatives |
| DK1859798T3 (en) * | 2001-03-29 | 2016-03-21 | Lilly Co Eli | N- (2-arylethyl) -BENZYLAMINER as antagonists of 5-HT6 receptor |
| ATE553190T1 (de) * | 2006-02-22 | 2012-04-15 | Brain Biotechnology Res & Information Network Ag | Neue halogenase |
| US10138205B2 (en) * | 2015-02-19 | 2018-11-27 | University Of Florida Research Foundation, Incorporated | Artificial self-sufficient cytochrome P450s |
| KR101934048B1 (ko) * | 2017-03-09 | 2019-03-26 | 고려대학교 산학협력단 | 플라빈-의존형 할로게나아제 및 이를 이용한 할로겐화 인돌 화합물의 제조방법 |
| US11591627B2 (en) * | 2018-03-21 | 2023-02-28 | University Of Florida Research Foundation, Incorporated | Modified bacteria for production of nitroaromatics |
| CA3132731A1 (en) * | 2019-03-07 | 2020-09-10 | University Of Padova | Compositions and methods of use comprising substances with neural plasticity actions administered at non-psychedelic/psychotomimetic dosages and formulations |
| WO2021226416A1 (en) * | 2020-05-08 | 2021-11-11 | Psilera Inc. | Novel compositions of matter and pharmaceutical compositions |
| WO2022047583A1 (en) * | 2020-09-02 | 2022-03-10 | Magicmed Industries Inc. | Nitrated psilocybin derivatives and use thereof for modulating 5-ht2a receptor and for treating a psychiatric disorder |
| WO2022115944A1 (en) * | 2020-12-01 | 2022-06-09 | Magicmed Industries Inc. | Carboxylated psilocybin derivatives and methods of using |
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| US12128058B2 (en) | 2024-10-29 |
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| EP4291549A4 (en) | 2025-01-22 |
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