KR20230147619A - 외인적으로 도입된 사이토카인을 발현하는 조작된 면역이펙터 세포 - Google Patents

외인적으로 도입된 사이토카인을 발현하는 조작된 면역이펙터 세포 Download PDF

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KR20230147619A
KR20230147619A KR1020237027889A KR20237027889A KR20230147619A KR 20230147619 A KR20230147619 A KR 20230147619A KR 1020237027889 A KR1020237027889 A KR 1020237027889A KR 20237027889 A KR20237027889 A KR 20237027889A KR 20230147619 A KR20230147619 A KR 20230147619A
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antigen
cell
domain
ccl
polypeptide
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Korean (ko)
Inventor
샤오후 판
지에 마오
퀴우추안 주앙
창지앙 장
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난징 레전드 바이오테크 씨오., 엘티디.
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Publication of KR20230147619A publication Critical patent/KR20230147619A/ko
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
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    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
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KR1020237027889A 2021-02-26 2022-02-25 외인적으로 도입된 사이토카인을 발현하는 조작된 면역이펙터 세포 Pending KR20230147619A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNPCT/CN2021/078227 2021-02-26
CN2021078227 2021-02-26
PCT/CN2022/077964 WO2022179613A1 (en) 2021-02-26 2022-02-25 Engineered immune effector cells expressing exogenously introduced cytokines

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KR20230147619A true KR20230147619A (ko) 2023-10-23

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KR1020237027889A Pending KR20230147619A (ko) 2021-02-26 2022-02-25 외인적으로 도입된 사이토카인을 발현하는 조작된 면역이펙터 세포

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US (1) US20240316201A1 (enExample)
EP (1) EP4298210A4 (enExample)
JP (1) JP2024507958A (enExample)
KR (1) KR20230147619A (enExample)
CN (1) CN116964195A (enExample)
WO (1) WO2022179613A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026022768A1 (ko) * 2024-07-24 2026-01-29 (주)티카로스 안전하며 효과적인 유전자세포치료 시스템

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