KR20230134524A - 무장된 세네카 밸리 바이러스 종양용해 요법 조성물및 그의 방법 - Google Patents

무장된 세네카 밸리 바이러스 종양용해 요법 조성물및 그의 방법 Download PDF

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KR20230134524A
KR20230134524A KR1020237027681A KR20237027681A KR20230134524A KR 20230134524 A KR20230134524 A KR 20230134524A KR 1020237027681 A KR1020237027681 A KR 1020237027681A KR 20237027681 A KR20237027681 A KR 20237027681A KR 20230134524 A KR20230134524 A KR 20230134524A
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cancer
seq
armed
seneca valley
valley virus
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Korean (ko)
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폴 엘. 할렌벡
수닐 차다
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세네카 세라퓨틱스, 인크.
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    • A—HUMAN NECESSITIES
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/768—Oncolytic viruses not provided for in groups A61K35/761 - A61K35/766
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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    • A61K38/46—Hydrolases (3)
    • A61K38/50—Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
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KR1020237027681A 2021-01-19 2022-01-19 무장된 세네카 밸리 바이러스 종양용해 요법 조성물및 그의 방법 Pending KR20230134524A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163138999P 2021-01-19 2021-01-19
US63/138,999 2021-01-19
PCT/US2022/013001 WO2022159508A1 (en) 2021-01-19 2022-01-19 Armed seneca valley virus oncolytic therapy compositions and methods thereof

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KR20230134524A true KR20230134524A (ko) 2023-09-21

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US (1) US20240307470A1 (https=)
EP (1) EP4281549A4 (https=)
JP (1) JP2024503703A (https=)
KR (1) KR20230134524A (https=)
CN (1) CN116761883A (https=)
AU (1) AU2022210419A1 (https=)
CA (1) CA3207261A1 (https=)
IL (1) IL304280A (https=)
WO (1) WO2022159508A1 (https=)

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Publication number Priority date Publication date Assignee Title
US20240076343A1 (en) 2022-06-16 2024-03-07 Cephalon Llc Anti-pd-1 antibody-attenuated il-2 immunoconjugates and uses thereof
WO2024177972A2 (en) * 2023-02-20 2024-08-29 The Wistar Institute Of Anatomy And Biology Antibody-cytokine chimeras

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7638318B2 (en) * 2003-09-26 2009-12-29 Norvartis Ag Seneca Valley virus based compositions and methods for treating disease
SG192673A1 (en) * 2011-02-10 2013-09-30 Roche Glycart Ag Mutant interleukin-2 polypeptides
EA201892619A1 (ru) * 2011-04-29 2019-04-30 Роше Гликарт Аг Иммуноконъюгаты, содержащие мутантные полипептиды интерлейкина-2
RU2696312C2 (ru) * 2014-07-16 2019-08-01 Трансген Са Онколитический вирус для экспрессии модуляторов иммунологических контрольных точек
CN111201035A (zh) * 2017-06-19 2020-05-26 梅迪塞纳医疗股份有限公司 Il-2超激动剂、激动剂及其融合体的用途和方法
MX2021001883A (es) * 2018-08-16 2021-07-15 Musc Found For Res Dev Virus recombinantes del mixoma y usos de los mismos.
US20220000921A1 (en) * 2018-11-20 2022-01-06 Innovative Cellular Therapeutics Holdings, Ltd. Modified Cell Expressing Therapeutic Agent and Uses thereof
JP2022516318A (ja) * 2019-01-04 2022-02-25 オンコラス， インコーポレイテッド カプセル化ポリヌクレオチド及び使用方法
US20220119478A1 (en) * 2019-01-15 2022-04-21 Caerus Therapeutics, Corp. Advanced chimeric antigen receptor vectors for targeting solid tumors
CN111154806A (zh) * 2020-01-08 2020-05-15 深圳普菲科生命科技有限公司 一种嵌合外源超级细胞因子的溶瘤病毒载体系统及其在药物中的应用
CA3207860A1 (en) * 2021-01-11 2022-07-14 Seneca Therapeutics, Inc. Seneca valley virus combination therapy to treat a cancer refractory to a checkpoint inhibitor

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EP4281549A1 (en) 2023-11-29
EP4281549A4 (en) 2025-05-07
AU2022210419A1 (en) 2023-07-20
AU2022210419A9 (en) 2025-03-06
WO2022159508A1 (en) 2022-07-28
JP2024503703A (ja) 2024-01-26
CN116761883A (zh) 2023-09-15
CA3207261A1 (en) 2022-07-28
US20240307470A1 (en) 2024-09-19
IL304280A (en) 2023-09-01

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