CN116761883A - 武装的塞尼卡谷病毒溶瘤性治疗组合物及其方法 - Google Patents

武装的塞尼卡谷病毒溶瘤性治疗组合物及其方法 Download PDF

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Publication number
CN116761883A
CN116761883A CN202280010849.XA CN202280010849A CN116761883A CN 116761883 A CN116761883 A CN 116761883A CN 202280010849 A CN202280010849 A CN 202280010849A CN 116761883 A CN116761883 A CN 116761883A
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cancer
armed
seq
nucleotide
saiikagavirus
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Chinese (zh)
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保罗·L·哈伦贝克
苏尼尔·哈达
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Seneca Therapy
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Seneca Therapy
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    • A61K35/768—Oncolytic viruses not provided for in groups A61K35/761 - A61K35/766
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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CN202280010849.XA 2021-01-19 2022-01-19 武装的塞尼卡谷病毒溶瘤性治疗组合物及其方法 Pending CN116761883A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163138999P 2021-01-19 2021-01-19
US63/138,999 2021-01-19
PCT/US2022/013001 WO2022159508A1 (en) 2021-01-19 2022-01-19 Armed seneca valley virus oncolytic therapy compositions and methods thereof

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CN116761883A true CN116761883A (zh) 2023-09-15

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US (1) US20240307470A1 (https=)
EP (1) EP4281549A4 (https=)
JP (1) JP2024503703A (https=)
KR (1) KR20230134524A (https=)
CN (1) CN116761883A (https=)
AU (1) AU2022210419A1 (https=)
CA (1) CA3207261A1 (https=)
IL (1) IL304280A (https=)
WO (1) WO2022159508A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240076343A1 (en) 2022-06-16 2024-03-07 Cephalon Llc Anti-pd-1 antibody-attenuated il-2 immunoconjugates and uses thereof
WO2024177972A2 (en) * 2023-02-20 2024-08-29 The Wistar Institute Of Anatomy And Biology Antibody-cytokine chimeras

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
US7638318B2 (en) * 2003-09-26 2009-12-29 Norvartis Ag Seneca Valley virus based compositions and methods for treating disease
SG192673A1 (en) * 2011-02-10 2013-09-30 Roche Glycart Ag Mutant interleukin-2 polypeptides
EA201892619A1 (ru) * 2011-04-29 2019-04-30 Роше Гликарт Аг Иммуноконъюгаты, содержащие мутантные полипептиды интерлейкина-2
RU2696312C2 (ru) * 2014-07-16 2019-08-01 Трансген Са Онколитический вирус для экспрессии модуляторов иммунологических контрольных точек
CN111201035A (zh) * 2017-06-19 2020-05-26 梅迪塞纳医疗股份有限公司 Il-2超激动剂、激动剂及其融合体的用途和方法
MX2021001883A (es) * 2018-08-16 2021-07-15 Musc Found For Res Dev Virus recombinantes del mixoma y usos de los mismos.
US20220000921A1 (en) * 2018-11-20 2022-01-06 Innovative Cellular Therapeutics Holdings, Ltd. Modified Cell Expressing Therapeutic Agent and Uses thereof
JP2022516318A (ja) * 2019-01-04 2022-02-25 オンコラス， インコーポレイテッド カプセル化ポリヌクレオチド及び使用方法
US20220119478A1 (en) * 2019-01-15 2022-04-21 Caerus Therapeutics, Corp. Advanced chimeric antigen receptor vectors for targeting solid tumors
CN111154806A (zh) * 2020-01-08 2020-05-15 深圳普菲科生命科技有限公司 一种嵌合外源超级细胞因子的溶瘤病毒载体系统及其在药物中的应用
CA3207860A1 (en) * 2021-01-11 2022-07-14 Seneca Therapeutics, Inc. Seneca valley virus combination therapy to treat a cancer refractory to a checkpoint inhibitor

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EP4281549A1 (en) 2023-11-29
EP4281549A4 (en) 2025-05-07
AU2022210419A1 (en) 2023-07-20
AU2022210419A9 (en) 2025-03-06
WO2022159508A1 (en) 2022-07-28
JP2024503703A (ja) 2024-01-26
CA3207261A1 (en) 2022-07-28
KR20230134524A (ko) 2023-09-21
US20240307470A1 (en) 2024-09-19
IL304280A (en) 2023-09-01

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